コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 es isomerized by light to the all-trans form be replaced with 11-cis retinal to regenerate the visual
2 bstantially developed; the 3beta-alcohol can be replaced with 3beta-H-bond donors such as sulfamide,
4 hich expert knowledge and parameter tweaking are replaced with a probability-based hypothesis test.
6 ty of bacterial ribonuclease P-can sometimes be replaced with a highly divergent homolog, the cellula
7 able for generic recruitment, since it could be replaced with a nonviral membrane-binding domain with
8 en semantic and environmental context should be replaced with a novel conceptualization of hippocampu
12 in which the beta,gamma-bridging oxygen has been replaced with a CXY group are useful chemical probe
13 s from the conventional azobenzene class has been replaced with a five-membered heteroaromatic ring.
15 However, the ancestral Zinderia symbiont has been replaced with a novel symbiont closely related to S
16 Now, we report that B cells in which Sgamma1 is replaced with a 28 I-SceI target array, designed to i
19 y as a single point on a free energy surface is replaced with a bithermal property that is derived fr
20 ect BRE and is abolished when the pf1089 BRE is replaced with a BRE from a strong archaeal promoter.
21 knockin mouse model in which endogenous p35 is replaced with a calpain-resistant mutant p35 (Deltap3
22 ere the selenocysteine (Sec) in position 188 is replaced with a cysteine (a construct named cVIMP-Cys
23 an be stabilized if one of the pyrrole rings is replaced with a furan ring to afford stable oxasmarag
24 In this strategy a null mutation in any gene is replaced with a genetically stable transgene that con
27 is not observed when the oxygen of 5-O-CH(3) is replaced with a larger atom (selenium or sulfur).
30 the apolar moiety of sulfonamide inhibitors is replaced with a more open, hydrophilic pocket in Hpal
32 upling between H(+) and sugar translocation, is replaced with a neutral side chain, the pH effect is
33 t S(2)/S(1)/triplet pathways for spheroidene is replaced with a new pathway for spheroidenone involvi
34 atable version of IDH2(R172K), in which K172 is replaced with a photocaged lysine (PCK), via genetic
35 lic hydroxyl and the keto oxygen in pyruvate is replaced with a potentially stronger hydrophobic inte
36 a-helix of the consensus 455 face in Sma0114 is replaced with a segment that shows high flexibility o
39 e, the normal left-right alternating pattern is replaced with a synchronized hopping gait, and the co
40 in which one of the three disulfide bridges is replaced with a thioether linkage, and evaluate the b
41 n, which requires an A/T-rich (W-box) motif, is replaced with a zygotic TSS selection grammar charact
42 the terminal phenyl group of the dibemethin was replaced with a 2-pyridyl group and in which the 4-a
43 frameshifting also occurred when the C-chord was replaced with a canonical slippery sequence from HIV
44 hemically labile oxindole hydrazide scaffold was replaced with a chemically and metabolically stable
45 spensable thymidine T2.1 in the 8-17 DNAzyme was replaced with a deoxyuridine, resulting in minimal c
47 a new mouse model in which endogenous MerTK was replaced with a genetically engineered variant that
49 , and the chimera Dap2alpha, in which the SA was replaced with a hydrophilic segment, with the propen
51 d efficiently to the VCCs when the NC domain was replaced with a leucine zipper dimerization motif th
53 trapping system, the propane permeation tube was replaced with a methyl mercaptan tube (a toxic, reac
54 21F variant in which the proximal tryptophan was replaced with a non-oxidizable phenylalanine exhibit
55 e question on technical skill of endoscopist was replaced with a question on patient comfort during e
56 re produced in which the epsilon-globin gene was replaced with a second marked beta-globin gene (beta
57 llite sequence; cells in which this sequence was replaced with a synonymous nonmicrosatellite sequenc
58 ological sensor, the fibrin clot end-product was replaced with a synthetic material under the biologi
62 E-cYFP-TM, where GPI anchor addition domains were replaced with a single-pass transmembrane domain, f
64 ease in which the current expectant approach is replaced with active attempts to uncover MRD before e
65 Lys residue at P3' of Pro-sigma(K) could not be replaced with Ala unless a Lys was provided farther C
66 utant in which an inverted Cys-Pro motif had been replaced with Ala residues fails to bind hemin with
69 en the serine and acidic residues of the SRT were replaced with Ala, Leu, and Gly, trans-activation a
72 ression of an H3.3 mutant in which serine 31 is replaced with alanine, the equivalent residue in H3.2
74 eE but not NleE(49AAAA52) where each of GITR was replaced with alanine restored the ability of an nle
75 art of the predicted binding pocket (Phe342) was replaced with alanine, the apparent affinity of the
78 residues (Cys 85, Cys 101) within this motif were replaced with alanine, and the effects of these rep
79 ant in which three Lys residues (KKK191-193) were replaced with alanine, and/or its other mutants wit
81 proposed to bind to the incoming duplex DNA were replaced with alanines, resulting in apparent loss
84 energy, and CO2 emissions reduction if they were replaced with alternatives that consume less energy
85 xazine (PA-824), in which the OCH(2) linkage was replaced with amide, carbamate, and urea functionali
88 Kunitz-3 and C-terminal domains of TFPIalpha are replaced with an alternative C-terminus that directs
89 lization that the arylglycine cap of 2 could be replaced with an alkylglycine derivative and still ma
90 oxyl group of the 4-hydroxybenzoic acid must be replaced with an amino group at some point in the bio
93 in which the native metal of a metalloenzyme is replaced with an abiological metal with reactivity di
96 ignificantly reduced when the mp-Al2 O3 film is replaced with an mp-TiO2 electron extraction and tran
97 cadherin through a flexible linker or if it was replaced with an actin-binding domain of utrophin.
98 , and not rLumY21A, where a tyrosine in each was replaced with an alanine, showed 60-fold decreased b
100 idgehead anilino group from our first series was replaced with an alkoxy or 1-ethenyl group were desi
101 insert of an anthropomorphic cardiac phantom was replaced with an aortic aneurysm model containing a
102 The normal Faraday plate collector electrode was replaced with an electrode "needle" used to concentr
103 he middle Pro residue within the tripeptides was replaced with analogues of varying ring sizes (azeti
104 The decomposition in the manual pipeline can be replaced with any NMF algorithm, for further generali
106 in which the 8 lysine amino acids of p5 have been replaced with arginine residues predisposing the pe
107 equivalent residue to K305 in human NHA2 has been replaced with arginine, which is a mutation that ma
112 hiazole ring system of the natural substrate was replaced with benzimidazole, benzofuran, benzothioph
114 ferase from Bacillus subtilis (MazF-bs(arg)) were replaced with Can by using the single-protein produ
118 back was eliminated when extracellular Na(+) was replaced with choline and significantly reduced by a
119 duction such that the normal simple granules were replaced with compound granules separated by amylop
120 , BPA in many consumer products is gradually being replaced with compounds such as bisphenol S (BPS).
124 position in the M2 membrane-spanning segment was replaced with Cys in dupalpha7 or dupDeltaalpha7, an
129 he myeloid lineage in which XIAP alleles can be replaced with disease-associated XIAP variants expres
130 replaced by O(6)-Bn-dG and cytosine C(9) has been replaced with dPer to form the modified O(6)-Bn-dG:
131 ified DDD in which cytosine at position C(9) is replaced with dPer to form the dG:dPer (DDD-GY) [5'-d
132 were hypoplastic, and the exocrine pancreas was replaced with ductal metaplasia that had increased a
133 erve terminals in which dynamin 1 and 3 have been replaced with dynamin 1 harboring dephospho- or pho
135 rated that a recombinant VSV where G protein is replaced with EBOV GP (rVSV-EBOV) is safe and highly
137 the P. berghei csp gene coding sequence has been replaced with either full-length P. vivax VK210 or
138 tructed versions of hLigI in which serine 51 was replaced with either alanine (hLigI51A) to prevent p
139 sensitivity of strains in which YvcK Thr-304 was replaced with either an alanine or a glutamic acid r
140 t at the C24 position of the natural product was replaced with either carbamates or ethers to provide
142 dels in which the three PKA sites in cMyBP-C were replaced with either phospho-mimic (DDD) or phospho
143 binding motif ESEV (which affects virulence) was replaced with ESKV, and NS1-138F (which is highly co
146 3) to 12-20 mug/m(3), when synthetic filters were replaced with fiberglass filtration media in the HV
148 at chimeric rhabdoviruses in which G protein is replaced with filovirus GP, widely used as surrogate
149 e useful in deciding whether orchiectomy can be replaced with follow-up or less invasive organ-sparin
151 and analgesia when water for injection (WFI) was replaced with glucose 5% (G5) for (90)Y-resin micros
152 tein (Cp183-EEE), in which three CTD serines are replaced with glutamate to mimic phosphorylated prot
153 the S segment and one in which the NSs gene was replaced with green fluorescent protein (GFP), allow
154 ously described a mouse model in which mDPP4 was replaced with hDPP4 such that hDPP4 is expressed und
155 and the intracellular transcriptional module are replaced with heterologous protein domains, can serv
156 ackage the newly replicated genome, they can be replaced with histone variants that alter nucleosome
158 e of transmission until April 2014 (60%) and was replaced with hospital exposure in June 2014-July 20
160 del in which the endogenous mouse Fgfr3 gene was replaced with human FGFR3(G380R) (FGFR3(ACH)) cDNA,
163 bed above, in which the stainless steel tube is replaced with Hydroguard fused silica tubing (0.53 mm
164 sential for antimicrobial activity and could be replaced with hydrophobic aliphatic or aromatic group
165 ovirus vaccine (OPV) will eventually need to be replaced with inactivated poliovirus vaccines (IPV).
166 HMGB-1 is sufficient to prime microglia, IS was replaced with intracerebral administration of disulf
167 In two of the 18 systems, Pb valve weights were replaced with iron, which decreased the observed Pb
171 Expensive, ineffective membrane materials are replaced with laminar flow and a nonselective, porou
172 sembly remained defective when D231 and K178 were replaced with larger charged residues or when their
173 s of the eastern Pacific Ocean, amphibactins were replaced with lower concentrations (1-2 pM) of hydr
174 % deionized water of polysulfide electrolyte was replaced with methanol to improve the wettability an
175 cally altered when one of the cytosine bases is replaced with methyl-, hydroxymethyl-, formyl-, or ca
176 ors were inactive when the plasmid substrate was replaced with mRNA, suggesting they interfered with
177 alogues in which the intracyclic Trp residue was replaced with natural, unnatural, and constrained am
178 xperiment, and then two members of the group are replaced with new participants, and the newly formed
179 pounds, where the tetramethylpiperidine ring was replaced with new scaffolds, led to improved antivir
181 of an internally tagged Cse4 reveals that it is replaced with newly synthesized molecules in S phase,
182 ins almost unchanged when CH meta to B and N is replaced with nitrogen, and becomes slightly weaker w
185 MP-13 active site, the Zn(2+) chelating unit was replaced with nonchelating polar residues that bridg
187 ember of the theta-defensin subfamily, could be replaced with noncovalent Watson-Crick hydrogen bonds
189 ions, in which three hydrophilic amino acids are replaced with nonpolar residues, that leads to dewet
191 4) mice, in which the coding region for BDNF is replaced with NT4, we examined whether the different
192 SST) means and annual cycles in all the GCMs are replaced with observed data from the ~4-km NOAA Path
193 site of a minimal type I hammerhead ribozyme were replaced with oligo-U loops, severely crippling or
194 R study indicated that the allyl group could be replaced with other substituents, with the most activ
195 lication in commercial products is gradually being replaced with other related compounds, such as bis
197 ) mice in which the entire T-cell repertoire was replaced with ovalbumin (OVA)-specific CD8(+) or CD4
198 ocodone, in which the N-methyl functionality was replaced with oxygen, sulfur, sulfoxide, and sulfone
199 ral phenylcyclopropyl amide side chain of 2a was replaced with p-fluorophenylisoxazole-carbonyl moiet
200 ompared with that of wild-type FVIII when it was replaced with P3-P3' residues flanking Arg(740) and
201 enerated in which Tyr(99) or Tyr(138) of CaM was replaced with Phe, generating mutant CaM, Phe(99)-Ca
202 a Syn5 RNA polymerase in which tyrosine 564 is replaced with phenylalanine (Y564F) that further decr
205 e knock-in mice in which serines 325/328/330 were replaced with phosphomimetic glutamic acids (S3E) o
206 empirical parameters in existing models must be replaced with physics- and biology-based terms anchor
207 at upon HIPK2-mediated phosphorylation, TCF3 is replaced with positively acting TCF1 at a target prom
208 ice in which the weakest S region, Sepsilon, is replaced with prominent recombination hotspot Smu.
210 Recently fish meal and oil have increasingly been replaced with proteins and oils from vegetable sour
213 niques are being used, where native subunits are replaced with receptors containing targeted mutation
216 ctivity of another nucleophile when His(nuc) is replaced with residues containing a small side chain
217 d increased to 5.1% and 7.3% when rice flour was replaced with retrograded and retrograded debranched
218 ibly life-threatening adverse effects, might be replaced with safer alternatives that do not have a B
219 ctor or saline), and their cocaine solutions were replaced with saline for 14 days to allow for extin
220 ated mice in which either IGCR1 CBE1 or CBE2 was replaced with scrambled sequences that do not bind C
221 midine (DB75) in which the central furan has been replaced with selenophene and/or one or both of the
222 template gp5/trx in which Cys-313 or Cys-275 is replaced with serine have 50 and 90%, respectively, o
223 FixK2(C183S)-His6) was used in which Cys-183 was replaced with serine and the C terminus was fused wi
226 he two intracellular regions of the receptor were replaced with serines using site-directed mutagenes
227 he extracellular domains of the TCR and pMHC were replaced with short hybridizing strands of DNA.
230 the nanoparticles within a binary lattice to be replaced with 'spacer' entities that are constructed
231 ng of other noncanonical bases, RNase H2 can be replaced with specific nicking endonucleases in this
232 e of sperm development during which histones are replaced with sperm-specific protamines to repackage
235 riazolopyrimidines wherein the p-SF5-aniline was replaced with substituted 1,2,3,4-tetrahydro-2-napht
236 e termed codon optimization, in which codons are replaced with synonymous ones in order to increase p
237 n which all 62,214 instances of seven codons were replaced with synonymous alternatives across all pr
239 phenyl derivatives in which the central ring is replaced with tetrafluoro-, tetramethyl-, or di-tert-
240 RNA constructs in which specific G residues are replaced with (th) G, an emissive isomorphic G surro
241 egment, the open reading frame (ORF) of LACV is replaced with that derived from JCV and is flanked by
242 nted genome in which the NSs coding sequence was replaced with that for the Gn and Gc precursor.
244 ric virus in which the ULb' region of TB40/E was replaced with that of AD169 showed reduced effects o
245 Ad5/3 vector in which the knob region of Ad5 was replaced with that of Ad3, conferring partial resist
246 ytoplasmic signaling C-terminal tail of FPR2 was replaced with that of FPR1 retained the PBP10 sensit
248 ne hepatitis virus (MHV) in which the N gene was replaced with that of its close relative, bovine cor
249 ch the gH transmembrane and cytoplasmic tail were replaced with that of human CD4 protein permitted c
250 ich large genomic regions of S. lycopersicum are replaced with the corresponding segments from S. pen
251 is-acting form of K28, each nucleotide could be replaced with the corresponding 2F analog without los
252 ne domain (at the C terminus) of CerS5 could be replaced with the corresponding sequence of CerS2 wit
253 wever, the first 158 residues of CerS5 could be replaced with the equivalent region of CerS2 without
255 V-1 MONITOR Test, version 1.5 (Amplicor) has been replaced with the COBAS AmpliPrep/COBAS TaqMan HIV-
256 muscle excitation-contraction coupling, has been replaced with the corresponding but nonfunctional l
257 nal sequence downstream of the kinase domain being replaced with the corresponding CRAF sequence.
258 conserved N terminus of the mature PilA1His is replaced with the corresponding N domain of FlgA1 is
260 mice (AKBI), in which the IkappaBalpha gene is replaced with the IkappaBbeta cDNA, we show that Ikap
261 r partially labile systems whenever the time is replaced with the product lability degree times t.
262 ) of the N170K/K297G double mutant of hRPE65 was replaced with the corresponding cRPE65 fragment, the
263 coding sequence from the start to stop codon was replaced with the corresponding human genomic region
264 23-21c, where the C-terminal domain of FGF23 was replaced with the corresponding regions from FGF21.
266 residues N-terminal to the acetylation site was replaced with the corresponding sequences from other
267 Lung cancer cells in which endogenous PKM2 was replaced with the Cys(358) to Ser(358) oxidation-res
269 histocompatibility complex class II antigen was replaced with the human leukocyte antigen DR4 (HLA-D
270 e IL-15Ralpha intracellular signaling domain was replaced with the intracellular portion of the IL-2R
271 drift tube for an ion mobility spectrometer was replaced with the IonCCD providing images of ion pro
272 which the ospA open reading frame, on lp54, was replaced with the ospC gene or the ospB gene, encodi
275 ich the N-terminal transmembrane domain of S was replaced with the transmembrane domain of the HCV en
276 ubstitution where all non-exchangeable atoms were replaced with the corresponding heavy isotope ((13)
277 Experiments in which regions of Far1 or Far2 were replaced with the corresponding region of the other
278 utative DNA binding loop regions of APOBEC3G were replaced with the corresponding regions from APOBEC
280 egions around the first aspartate rich motif were replaced with the corresponding regions of FPP synt
281 sive to neurounina-1 when both alpha-repeats were replaced with the corresponding regions of NCX1.
282 1b laboratory (lab) strains (H77c and Con1) were replaced with the corresponding regions of specimen
283 second extracellular loops of CD81 and OCLN were replaced with the respective human sequences, which
284 C911 because bases 9 through 11 of the siRNA are replaced with their complement, was able to complete
285 ariant exchange, in which canonical histones are replaced with their variant counterparts, is an enti
290 anef were constructed in which env sequences were replaced with those of the heterologous strain E543
291 membrane and cytoplasmic tail (TMCT) domains were replaced with those of the HPIV1 F protein in an ef
292 moval was needed due to stent migration, and was replaced with three stents telescopically aligned to
293 DsbA2, a cis-proline residue at position 198 was replaced with threonine that enables formation of st
295 the Ala residues at different positions have been replaced with Trp residues, has been investigated.
296 sors interacted with PU.1 if wild-type RUNX1 was replaced with truncated variants associated with leu
297 ng faces of the outward-facing cavity walls, are replaced with Tyr or Phe, and reduced quenching is o
298 polymers where one of the four normal bases is replaced with various cationic, anionic or neutral an
300 In South Africa, sputum smear microscopy has been replaced with Xpert MTB/RIF as the initial diagnost
WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。