ライフサイエンスコーパス: be sensed by

1 ed to be mediated by peptide pheromones that are sensed by a class of G protein-coupled receptors, vo

2 These DAMPs are sensed by a pattern recognition receptor called NLRP

3 Changes in ligand concentrations are sensed by a protein assembly consisting of transmemb

4 In the nematode C. elegans, these cues are sensed by a small number of olfactory neurons, each

5 l pathogen-associated molecular patterns can be sensed by a growing number of host cell cytosolic pro

6 ct evidence suggests that oxygen tension may be sensed by a hemoprotein.

7 Matrix stiffness that is sensed by a cell or measured by a purely physical pro

8 Proliferation-associated DNA damage is sensed by a complex comprising caspase-8, FADD, c-FLI

9 Hcy is sensed by a constitutive protein complex composed of

10 We conclude that lumenal glucose is sensed by a glucose sensor, distinct from SGLT1, resi

11 Oxygen, an essential nutrient, is sensed by a multiple of cellular pathways that facili

12 CO2 is sensed by a population of olfactory sensory neurons i

13 that cyclic di-GMP in many bacterial species is sensed by a riboswitch class in messenger RNA that co

14 ry, in which a binding event in one protomer is sensed by a second symmetric protomer.

15 We find that spindle position is sensed by a system composed of MEN-inhibitory and -ac

16 One peptide, known as CSP, is sensed by a two-component signal transduction system

17 Virus infection is sensed by a variety of cellular pattern-recognition r

18 nerates microdomains of elevated Ca(2+) that are sensed by adjacent mitochondria.

19 provide evidence that elevated CO(2) levels are sensed by AECs and that AMPK mediates CO(2)-induced

20 Cytosolic DNA is sensed by AIM2-like receptors (ALRs) during bacterial

21 data suggest that chromatin assembly defects are sensed by an ATM-dependent intra-S phase chromatin q

22 arginine, glutamine, lysine, and methionine) are sensed by an indirect mechanism.

23 These viral DNAs are sensed by an unidentified host sensor that triggers

24 mary translation product ComS, is thought to be sensed by an intracellular receptor, ComR, after upta

25 A small subset of these compounds is sensed by animals and humans, and the volatile profil

26 r results show that components of food (fat) are sensed by antral cilia on endocrine cells, which mod

27 The IR radiation is sensed by applying a dc bias voltage to each antenna

28 hibition of Cu(II) reduction, responses that are sensed by ArcBA and CusRS respectively.

29 t the concentration of L-arginine in the LCV is sensed by ArgR to produce an intracellular transcript

30 together, our results indicate that Brucella is sensed by ASC inflammasomes that collectively orchest

31 The persisting complexes are sensed by ataxia telangiectasia mutated (ATM), a pro

32 ecular mechanisms by which stress conditions are sensed by bacteria, how related signals are discrimi

33 als, involved in interkingdom communication, are sensed by bacterial sensor kinases.

34 e hypothesized that anabolic nutrients would be sensed by both AMPK and mTOR, resulting in an acute a

35 g-like feedback loop where the produced IL-2 is sensed by both the activated CD4(+) T cell pool and b

36 Poly I:C is sensed by both TLR3 in the endosomes and melanoma dif

37 ciated gene 5 (MDA5) inside cells, rotavirus was sensed by both RIG-I and MDA5, alone and in combinat

38 The level of stored Ca2+ is sensed by Ca(2+)-permeant channels in the plasma memb

39 nges in intracellular calcium concentrations are sensed by calmodulin, a signal transduction protein

40 pothesis that adenosine and nitric oxide can be sensed by capillaries and are implicated in the remot

41 Thus, muscle contraction can be sensed by capillaries and the signalling mechanism fo

42 gical responses, indicating that eNAD(+) may be sensed by cell-surface receptors.

43 th diseases is how the loss of cell polarity is sensed by cell death machinery.

44 we reasoned that their metabolic by-products are sensed by cells of the immune system and affect the

45 rom strain, pressure, and fluid shear stress are sensed by cells through an unidentified mechanorecep

46 How physical force is sensed by cells and transduced into cellular signalin

47 Little is known, however, about how sulfate is sensed by cells.

48 ulp had low concentrations of S1P, while S1P was sensed by cells inside the white pulp near the margi

49 beta following ligand binding; changes which are sensed by cellular factors (coactivators) required f

50 Although several DNA viruses are sensed by cGAS, viral strategies targeting cGAS are

51 occurring changes in APS concentrations may be sensed by changes in the conformation of PAPSS2.

52 presence of recombination intermediates that are sensed by checkpoints.

53 with stark increases in succinate, which can be sensed by Cra.

54 that several gut microbial-derived products are sensed by dedicated host receptor systems to alter c

55 ualities (sweet, bitter, salty, sour, umami) are sensed by dedicated taste cells (TCs) that relay qua

56 Amino acid starvation is sensed by depletion of the aminoacylated tRNA pools,

57 Injury to a target organ is sensed by distant stem cells, which migrate to the si

58 fects of various types of DNA lesions, which are sensed by distinct pathways to recruit repair factor

59 tal stimuli such as temperature and pressure are sensed by dorsal root ganglion (DRG) neurons.

60 Body size is sensed by either stretch receptors or oxygen restrict

61 In Bacillus subtilis, this labile pool is sensed by equilibration with the metalloregulator Zur

62 primary product of oxidative metabolism, can be sensed by eukaryotic cells eliciting specific respons

63 In Arabidopsis, the hormone ethylene is sensed by five related receptors, all of the 'two-com

64 tors, and their intracellular concentrations are sensed by gene-regulatory mRNA domains (riboswitches

65 anscription, a variety of input signals must be sensed by genetic regulatory proteins.

66 that binding to SAalpha2,3 by H5N1 HPAIV may be sensed by human cells differently than binding to SAa

67 he intestine, diverse environmental cues can be sensed by immune cells, which must balance resistance

68 tudy, we explored whether acidic environment is sensed by immune cells as an inflammasome-activating

69 Thus, centromere tension can be sensed by increased spatial separation of Aurora B fr

70 Pathogens are sensed by innate immune receptors that initiate an e

71 s (damage-associated molecular patterns) can be sensed by innate cells, which drives type I interfero

72 Excessive nutrients can be sensed by innate pattern recognition receptors as dan

73 However, the mechanisms by which heme is sensed by innate immune cells contributing to these d

74 away from a directional light source, which is sensed by intracellular photoreceptors and mediated b

75 ER stress is sensed by Ire1, a transmembrane kinase/endoribonuclea

76 back mechanism in which the secreted hormone is "sensed" by its respective receptor and initiates syn

77 ry pathway is described in which excess iron is sensed by its ability to catalyze site-specific oxida

78 Gases are sensed by lung cells and can activate specific intra

79 is known about the signaling molecules that are sensed by LuxR solos.

80 cing enzyme heme oxygenase (HO1) and that CO is sensed by M. tuberculosis to initiate a dormancy prog

81 This second messenger is sensed by macromolecular targets inside the cell, bot

82 e cell-autonomous signals delivered by agrin are sensed by macrophages through the alpha-DC (DG) rece

83 Mate contact is sensed by male-specific sensilla of the tail, the ray

84 S. aureus is sensed by many pattern recognition receptors, includi

85 ith encephalomyocarditis virus (EMCV), which is sensed by MDA5, Trim13(-/-) mice produce increased am

86 Environmental arsenic is sensed by members of the ArsR/SmtB family.

87 nsduced into common metabolomic changes that are "sensed" by metabolite-responsive regulators, such a

88 ded by ligands of the semaphorin family that are sensed by migrating neuronal growth cones through pl

89 Calcium signals are sensed by mitochondria acting in concert with mitoch

90 rs of innate antiviral immune responses that are sensed by multiple classes of sensors, but other ind

91 hypocotyl photomorphogenesis, light signals are sensed by multiple photoreceptors, among which the r

92 w a vast array of extracellular signals that are sensed by multiple sensory transduction pathways whi

93 er the local submembrane [Ca]i ([Ca]sm) that is sensed by NCX dynamically during the action potential

94 This glutamatergic gliotransmission is sensed by neurons of the dorsal SCN via specific pre-

95 However, translocated bacterial products are sensed by nucleotide binding domain and leucine-rich

96 he concept that ribonucleotide depletion can be sensed by p53, resulting in a G(1) cell cycle block.

97 icrobe-associated molecular patterns (MAMPs) are sensed by pattern recognition receptors (PRRs) on ce

98 en- and damage-associated molecular patterns are sensed by pattern recognition receptors, including m

99 How poxviruses are sensed by pDCs to induce type I IFN production is no

100 released from necrotic cells are thought to be sensed by phagocytes leading to secretion of IL-1alph

101 oncentrations of magnesium, the ion known to be sensed by PhoQ.

102 -activated genes is induced by Fe(3+), which is sensed by PmrA cognate sensor PmrB, and by low Mg(2+)

103 erases and a subclass of sirtuins (writers), is sensed by proteins that contain binding modules (read

104 Natural sugars and artificial sweeteners are sensed by receptors in taste buds.

105 extracellular signal of the TGF-beta ligand is sensed by receptors and transmitted into the nucleus

106 ral cases, the pK(a) of a particular residue was sensed by resonances not only in that residue but al

107 t by the release of neurotransmitters, which are sensed by responding neurons through cognate recepto

108 Previously, it was unclear which signals are sensed by salmonellae to promote PhoQ-mediated virul

109 ditis elegans, gentle touch to the body wall is sensed by six mechanosensory neurons that express two

110 Streptomyces secrete dodecanoic acid, which is sensed by SRB-6.

111 emptying of IP(3)-sensitive ER Ca(2+) stores are sensed by STIM1 molecules which aggregate and move c

112 Cues from the external environment are sensed by surface receptors, and complex signaling m

113 A surprising discovery was that L-leucine is sensed by Tar as an attractant at low concentrations

114 tion of the cytosolic leaflet, both of which are sensed by the +ALPS motif.

115 ges in the luminal concentrations of alphaKG are sensed by the alphaKG receptor OXGR1 expressed in th

116 Here we review how viruses are sensed by the cGAS-STING signaling pathway as well a

117 Temporal changes in solute concentration are sensed by the chemotaxis system in Escherichia coli,

118 These environmental stimuli, which are sensed by the DosS heme group, result in autophospho

119 These ligands are sensed by the heme domain of sGC, which belongs to t

120 Here, we ask what properties of CFTR are sensed by the Hsp27-Ubc9 pathway by examining the ab

121 the effects of chemotherapy and radiotherapy are sensed by the immune system, their combination with

122 Infections with RNA viruses are sensed by the innate immune system through membrane-

123 the mechanism by which cyclic dinucleotides are sensed by the innate immune system.

124 ted through the VNO, whereas other chemicals are sensed by the MOE, recent evidence suggests that som

125 Here, we show that necrotic cells are sensed by the Nlrp3 inflammasome resulting in the su

126 d yeast cells secrete mating pheromones that are sensed by the partner which responds by growing a ma

127 The three signals are sensed by the QseC histidine kinase (HK) sensor.

128 pon translation of the NBD1 and R-domain and are sensed by the RMA-1 ubiquitin ligase complex.

129 Excessive caloric intake is thought to be sensed by the brain, which then activates thermogenes

130 Thus, signal input to the Frz system must be sensed by the conserved C-terminal module of FrzCD an

131 These proteins can also be sensed by the plant immune system, leading to restric

132 ce from the locations where disturbances had been sensed by the moving limb.

133 y concealing a pathogen-induced process from being sensed by the inflammasome.

134 Saccharomyces cerevisiae, extracellular [Pi] is "sensed" by the inositol-hexakisphosphate kinase (IP6

135 he methylation status of these two sequences is sensed by the action of two proteins, Lrp and PapI, a

136 In Caenorhabditis elegans, gentle touch is sensed by the anterior (ALM and AVM) and posterior (P

137 The released ASN is sensed by the bacteria, altering the expression of ap

138 ttle is known about how biomechanical stress is sensed by the cardiomyocyte sarcomere to transduce in

139 the addition of nocodazole and this process is sensed by the cell QCM biosensor.

140 ibosomal proteins, suggesting that collision is sensed by the cell to initiate downstream quality con

141 This "error" is sensed by the central nervous system via increases in

142 he channel, increasing the local stress that is sensed by the channels and stabilizing the expanded c

143 We find that nutrient stress is sensed by the class IV multidendritic cholinergic neu

144 ATP is sensed by the coupling/uncoupling of transcription of

145 At the instant a change in the color is sensed by the detector, the titrant flow rate FH is h

146 ne but it remains uncertain (1) how pressure is sensed by the endothelium and (2) how the vascular re

147 t in gonadotrophs an oscillatory Ca2+ signal is sensed by the exocytotic apparatus in a modified form

148 DNA damage is sensed by the highly conserved recombination protein

149 prevalent in T. vaginalis clinical isolates, is sensed by the human epithelial cells via Toll-like re

150 Here we examined how bee venom PLA2 is sensed by the innate immune system and induces a type

151 ow UV irradiation of epidermal keratinocytes is sensed by the innate immune system, but also show tha

152 ic groups of streptococci, the pheromone XIP is sensed by the intra-cellular regulator ComR, that in

153 ATP, released during cell damage/activation, is sensed by the ionotropic purinergic receptor P2X7 (P2

154 The defect in the top1 trf4-ts mutant is sensed by the MAD1-dependent spindle assembly checkpo

155 hat Comamonas DA1877 generates a signal that is sensed by the nematode.

156 we show that infection with Candida albicans is sensed by the Nlrp3 inflammasome, resulting in the su

157 y the PmrB protein, and in low Mg(2+), which is sensed by the PhoQ protein.

158 be activated independently by Fe(3+), which is sensed by the PmrB protein, and in low Mg(2+), which

159 We propose that this transition is sensed by the portal that is embedded in the capsid w

160 This depletion is sensed by the protein STIM1 in the endoplasmic reticu

161 Nitrite binding at type 2 Cu is sensed by the proton abstracting group Asp92 and the

162 hat IL-1beta produced by hematopoietic cells is sensed by the radioresistant compartment to promote b

163 We demonstrate that DHMA is sensed by the serine chemoreceptor Tsr and that the c

164 se1 during G1 produced a spindle defect that is sensed by the spindle assembly checkpoint.

165 ansfer imparts a polarity on the target that is sensed by the transposon.

166 ity on the channel's extracellular face that was sensed by the activation gating machinery.

167 The released DNA, in turn, was sensed by the DNA receptor absent in melanoma 2.

168 roducts, 2-monoacylglycerol and fatty acids, were sensed by the mice, and self-administration pattern

169 whereby a change in renal perfusion pressure is sensed by these cells and results in a change in reni

170 nt combinations lead to an intermediate that is sensed by these checkpoint functions.

171 zed with Staphylococcus aureus (S.a.), which are sensed by Toll-like receptor 2 (TLR2).

172 Pathogens are sensed by Toll-like receptors (TLRs) and a growing n

173 Nucleic acids from microbes are sensed by Toll-like receptors 7/9 (TLR7/9), which ar

174 LPS is sensed by Toll-like receptor 4 (TLR4) in complex with

175 RNA is sensed by Toll-like receptor members TLR3, TLR7 and T

176 Subunit misfolding in the absence of PapD was sensed by two parallel pathways: the Cpx two-compone

177 We speculate that urea can potentially be sensed by uropathogenic bacteria to initiate infectio

178 Changes in the intestinal microenvironment are sensed by vagal, spinal, and intrinsic primary affer

179 However, it is not known whether FAs are sensed by ventral tegmental area (VTA) dopamine (DA)

180 Depolarization is sensed by VSD-charged residues residing in the membra