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8 gonistic selection among diploids, which has been shown to be a potent driver of the strata and reduc
10 2-(18)F-fluorodeoxysorbitol ((18)F-FDS) has been shown to be a promising agent with high selectivity
11 ace amine-associated receptor 1 (TAAR1), has been shown to be a promising target to prevent stimulant
13 MSA around the gastroesophageal junction has been shown to be a safe and effective therapy for gastro
14 tron emission tomography of the pancreas has been shown to be a surrogate imaging biomarker of pancre
15 imes (T1) by cardiac magnetic resonance have been shown to be a surrogate marker of diffuse myocardia
24 s Perspective, the "necessary nitrogen atom" is shown to be a versatile high-impact design element fo
26 ecombinant vesicular stomatitis virus (rVSV) was shown to be a highly effective and safe vector for t
27 sport in leaves under canopy solar radiation was shown to be a major contributor to this difference.
30 per point sampling and fluorescence staining was shown to be a rapid method, able to detect residual
31 HBoV1 is the first parvovirus whose NS1 has been shown to be able to activate all three PI3KKs (ATM,
32 of monocyte/macrophage (M) development, has been shown to be able to instruct the lineage choice of
33 ntroduced into Aedes aegyptimosquitoes, have been shown to be able to spread to high frequencies in m
34 r 2D capping layer with high Young's modulus is shown to be able to effectively suppress the dewettin
35 t of this pathway - i.e., the amygdala - has been shown to be abnormally activated in paradigms where
39 eks after radiation that have not previously been shown to be altered after radiation to the lung.
44 ides for insect control, and this fungus has been shown to be an effective pathogen of B. tabaci.
47 spectrometry combined with thermochemolysis is shown to be an excellent analytical tool to simultane
48 dition, digalactosyl diglyceride (DGDG) 36:4 was shown to be an effective marker differentiating betw
53 ique in a miniaturized droplet format, which is shown to be as reliable as its macroscopic test tube
56 (BCAAs) and aromatic amino acids (AAAs) have been shown to be associated with insulin resistance and
57 ium and the left atrial appendage which have been shown to be associated with ischaemic stroke risk.
59 aberrations (CAs) in blood lymphocytes have been shown to be associated with overall cancer risk and
60 e are patterns of reuse that have previously been shown to be associated with percolation errors.
62 ather in the Northern Hemisphere summer have been shown to be associated with the presence of high-am
63 ultiple cytokines simultaneously, which have been shown to be associated with viral control, could be
66 A resulted in dose-dependent mortality which was shown to be attributable to down-regulation of targe
67 ycle and an appended polyamine component and was shown to be both antimetastatic and cytotoxic to hum
68 ever, cells of the innate immune system have been shown to be capable of displaying long-term functio
69 ced actuators, because these have previously been shown to be capable of producing a wide range of mo
72 FT) calculations, the accelerated KMC method is shown to be capable of efficiently calculating hydrog
73 addition, the crosstalk reduction technique is shown to be capable of improving the coupling lengths
75 d in experiments with rat brain sections and was shown to be capable of visualizing and spatially cha
83 es, the phytochrome-PIF signaling module has been shown to be conserved from Physcomitrella patens to
86 lanocortin (POMC) neurons in particular have been shown to be critical regulators of metabolism and r
87 tercalated cells (ITCs) of the amygdala have been shown to be critical regulatory components of amygd
89 GOF mutant p53 in promoting lung metastasis is shown to be critically dependent on the transcription
90 loop, comprising 11-amino-acid residues, has been shown to be crucial for substrate transport, as dru
92 Urea-nucleobase stacking interactions have been shown to be crucial in urea-assisted RNA unfolding.
93 size and arrangement of the aromatic panels were shown to be crucial for achieving effective encapsu
98 glycolytic and glutamine metabolism pathways were shown to be deregulated in pancreatic ductal adenoc
99 l of 23,709 genes and 12 metagenomic species were shown to be differentially abundant between ankylos
100 revealed mutations in the gK locus, but UL21 was shown to be dispensable for UL20(Syn) and UL24(Syn)
101 rology, the various stages of lignin removal are shown to be distinguished through the observed morph
103 buse), an old alcohol-aversion drug that has been shown to be effective against diverse cancer types
104 l or subcutaneous allergen immunotherapy has been shown to be effective and to induce long-term toler
107 ementation or the fortification of foods has been shown to be effective in preventing and treating ir
108 upportive, and no specific therapeutics have been shown to be effective in reducing incidence or seve
111 es self-management education programmes have been shown to be efficacious and cost-effective in promo
112 eduction of LPA levels in plasma in vivo and was shown to be efficacious in a bleomycin-induced pulmo
115 embrane, whereas mammalian TPC channels have been shown to be endo/lysosomal Na(+)-selective or Ca(2+
116 a high degree of galactosyl substitution and was shown to be endo-acting generating a more diverse mi
117 hat regulates local protein translation, has been shown to be enriched in NL dendrites, suggesting it
118 sitive and negative SNV and INDEL calls that were shown to be enriched among discordant calls but als
119 cortex (dACC) and anterior insula (AI), have been shown to be equally sensitive to the detection of s
120 lecules NCAM and L1, which were the first to be shown to be essential not only in development but als
121 ransferases identified in mammals, Set1A has been shown to be essential for early embryonic developme
122 gulation of ICOS and ICOS ligand (ICOSL) has been shown to be essential for maintaining proper immune
123 n Stimulator of Interferon Genes (STING) has been shown to be essential for recognition of both viral
126 rminal acetylation, and phosphorylation have been shown to be essential for the regulated assembly an
128 Serotonin or 5-hydroxytryptamine (5-HT) has been shown to be essential in lots of physiological and
130 of the dxy orbital due to c-axis contraction is shown to be essential to explain the insulating phase
131 yeloid leukemia (CML), where BCL6 expression was shown to be essential for CML stem cell survival and
132 conserved ER membrane protein complex (EMC) was shown to be essential for efficient insertion in vit
133 One such protein, Cox16p, encoded by COX16, was shown to be essential for the activity and assembly
135 l metal/ceria and ceria/metal catalysts have been shown to be excellent systems for studying fundamen
136 vailable beta-carbonyl-substituted aldehydes are shown to be exceptional substrates for Rh-catalyzed
137 ptor expressed on myeloid cells (TREM)-2 has been shown to be expressed on DCs in several disease mod
139 wn contents of the (12)C lignin analogue and was shown to be extremely accurate (>99.9%, R(2) > 0.999
140 (64)Cu-DOTATATE is a new PET tracer that has been shown to be far superior to the SPECT tracer (111)I
141 e reaction between CH3O2 and OH radicals has been shown to be fast and to play an appreciable role fo
144 ethod is demonstrated for three proteins and is shown to be fully compatible with disulfide bridges,
145 side bisphosphonates (ANbPs) have previously been shown to be good inhibitors of human hypoxanthine-g
146 mpler-tissue exchange was isotropic, and PRC were shown to be good indicators of sampler-tissue equil
147 beta-cell states.Betaeta-cells have recently been shown to be heterogeneous with regard to morphology
148 , dual hydrogen-bond donating bistriflamides are shown to be highly effective in activating alpha,bet
150 In phase 1 and 2 studies, ceritinib has been shown to be highly active in both ALK inhibitor-nai
152 or pregnant women in the third trimester has been shown to be highly effective in reducing 90% of vac
153 factors are surprisingly relevant: PTSD has been shown to be highly heritable despite being definiti
158 y, in vitro-generated induced Tregs (iTregs) were shown to be highly plastic and capable of inducing
159 calibration burden; analyte response curves were shown to be highly repeatable for up to 7 months.
163 The proinflammatory effects of MSU crystals were shown to be IL-1-dependent using a caspase-1 inhibi
164 sanoids are a group of bioactive lipids that are shown to be important mediators of neutrophilic infl
165 ctin toxicity in host bacteria and which has been shown to be important for bacterial viability.
166 the meningeal spaces and choroid plexus) has been shown to be important for brain tissue maintenance
167 proteins with proapoptotic function, Bim has been shown to be important for clonal deletion in severa
169 se-causing pathogen Borrelia burgdorferi has been shown to be important for generating an inflammator
170 ype-A2), a tyrosine kinase receptor that has been shown to be important for lens development and to c
171 Beyond classical immune functions, they have been shown to be important for organogenesis, spermatoge
172 Innate regulation through TLR signaling has been shown to be important for promoting T cell subset d
174 orm, Orb2A, has a unique N-terminus that has been shown to be important for the formation of amyloid-
175 d RicT (previously YmcA, YlbF and YaaT) have been shown to be important regulatory proteins for multi
176 The extracellular amino terminus of gK has been shown to be important to the ability of the prototy
179 wide particle size distribution of PLGA NMP was shown to be important in producing a compact structu
182 signaling in the absence of TIEG1 expression is shown to be in part due to impaired beta-catenin nucl
183 re ambient pressure experimental data, which are shown to be inconsistent with a 9R phase for the low
187 late the immune response, they have recently been shown to be involved in lipid remodeling and scaven
189 ) family of transcription factors which have been shown to be involved in numerous signaling pathways
191 daptive immune response to pathogens, it has been shown to be involved in several non-infectious phys
196 ontally transferred genes, but some of these were shown to be involved in entry into anhydrobiosis.
198 y over the right prefrontal cortex-which has been shown to be linked to risk behavior-may lead to inc
199 ic reticulum, where ABA 8'-hydroxylases have been shown to be localized, and that it functions as an
200 velopment of CRTs is inflammation, which has been shown to be modulated by diet.We aimed to investiga
201 otide phosphorylase (PNPase), has previously been shown to be modulated by the Krebs cycle metabolite
204 s frequent administration at lower doses-has been shown to be more efficacious than maximum tolerated
209 Furthermore, Nedd8 binding site in Smurf is shown to be necessary for its ubiquitin ligase activi
210 Monocyte chemoactive protein 1 (MCP1) has been shown to be neuroprotective and is released by astr
211 is a programmed cell death pathway that has been shown to be of central pathophysiological relevance
213 a "historic" CA-MRSA from Western Australia, were shown to be only distantly related to recent USA300
215 ing rationale is that negative emotions have been shown to be particularly powerful in securing atten
220 isolated from the peripheral blood and have been shown to be powerful markers of disease progression
221 nvertase subtilisin/kexin type 9 (PCSK9) has been shown to be predictive of cardiovascular events (CV
223 alpha4beta7(high) CD4(+) T lymphocytes have been shown to be preferentially targeted by human immuno
226 the USPIO contrast agent labeled macrophages were shown to be present in the depot region of the GSK1
229 anistically, the observed enantioselectivity was shown to be primarily a function of differential fun
230 mphocyte ratio (PLR) and platelet count (PC) were shown to be prognostic in several solid malignancie
233 stem, energetic coupling between domains has been shown to be quantitatively equivalent to that betwe
235 sistance of activated/BRE-functionalized pCB is shown to be recovered only by covalent attachment of
238 s) of MICA, MICB, and UL16-binding protein 2 were shown to be regulated by RBPs and microRNAs, usuall
241 he first time that one of these adhesins has been shown to be required for binding of multiple glycan
242 tor functions.NFAT nuclear translocation has been shown to be required for CD8(+) T cell cytokine pro
245 unknown, unlike nucleosome reassembly which is shown to be required for other DNA repair processes.
248 rals, Fe(III) oxides particles have recently been shown to be responsible for the protection and buri
252 topoietic cell transplantation (HCT) has now been shown to be safe and effective for selected HIV-inf
253 cines based on mRNA coding for antigens have been shown to be safe and immunogenic in preclinical mod
254 treatment in concomitance with chemotherapy was shown to be safe and effective in influencing remiss
255 ed West Nile virus vaccine, rWN/DEN4Delta30, was shown to be safe and immunogenic in healthy adults a
256 e competitive antagonists of apelin receptor were shown to be safe and effective in reducing tumour e
261 Gs Conformational changes in Golf activation are shown to be similar to those in Gs Overall the curre
265 head box C1 (FOXC1) transcription factor has been shown to be specifically overexpressed in TNBC and
267 enchymal-transition (EMT) inducer (ILEI) has been shown to be strongly up-regulated in several cancer
268 ionally, the increase in failure probability is shown to be strongly affected by compounding effects.
270 acids, while PLFA molecular weight fractions are shown to be structurally similar by Fourier-transfor
271 ucuronides, and carbamoyl glucuronides, have been shown to be substrates or time-dependent inhibitors
272 roteins, as only a few sequence changes have been shown to be sufficient to alter resistance specific
273 The intertrapping column retention time is shown to be sufficiently reproducible for scheduled s
274 In particular, this class of receptors has been shown to be suitable for the effective complexation
275 acid (ATRA) plus arsenic trioxide (ATO) has been shown to be superior to ATRA plus chemotherapy in t
276 For primary PC, PSMA ligand PET imaging has been shown to be superior to cross-sectional imaging for
277 unless and until a full fixation-based model is shown to be superior to extant item-based models.
279 ed by ethanol precipitation of polyphosphate was shown to be superior to the other tested method vari
280 lization and tuning of its properties, as it is shown to be susceptible to a subsequent, highly selec
281 duction of O2 , and the formation of nanoDVD are shown to be synergistic with phototherapy to improve
285 mmunoglobulin-cytokine fusion molecules have been shown to be the new generation of immunomodulating
288 ted access to all particles, while diffusion was shown to be the only prevailing transport mechanism.
292 irus 1 (HSV-1) VC2 vaccine strain, which has been shown to be unable to enter into neurons and establ
294 re proinflammatory lipid mediators that have been shown to be upregulated in several diseases, includ
300 horylation, and this particular modification was shown to be vital for axonal growth and dendritic br
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