ライフサイエンスコーパス: be significantly downregulated

1 continue to be expressed, but ACY expression is significantly downregulated.

2 novo acute myeloid leukaemia (AML) where it is significantly downregulated.

3 K signaling, while invasion-associated genes are significantly downregulated.

4 TGF-beta1 and several collagen genes were significantly downregulated.

5 st and cell contractility-related molecules, were significantly downregulated.

6 gene MEFV was upregulated, CD40LG and PYDC1 were significantly downregulated.

7 Runx2 and its downstream genes Odam and Amtn were significantly downregulated.

8 osomal genes, and lysosomal gene expression, were significantly downregulated.

9 Specific colonocyte genes were significantly downregulated.

10 ficantly upregulated in SO, but 27 microRNAs were significantly downregulated.

11 were unaltered, and other astrocytic markers were significantly downregulated.

12 lion (DRG) of CHF rats whereas VR1 receptors were significantly downregulated.

13 OCN was significantly downregulated (70%) at the lowest dose

14 d respiratory electron transport pathways to be significantly downregulated after RK-33 or DDX3 knock

15 tudies have identified gene transcripts that are significantly downregulated and upregulated in the e

16 In Keap1MuKO mice, blood glucose levels were significantly downregulated and the levels of the g

17 henotypes: extracytoplasmic stress responses are significantly downregulated, and the production of o

18 miR-224 was significantly downregulated as ameloblasts different

19 f DFNA5 in four of five colon cancer tissues was significantly downregulated as compared to normal ti

20 BDNF itself was significantly downregulated at the RNA and protein l

21 r results showed that dendritic HCN channels were significantly downregulated at an acute time point

22 were significantly upregulated, and 29 genes were significantly downregulated at one or more time poi

23 metabolism (PCK2, PFKL, IDH2, ACY1, and ADA) are significantly downregulated because of the accumulat

24 scripts for TLR7, RelA, IFN-gamma, and IP-10 were significantly downregulated between 2- and 3-fold i

25 ding small RNA miR-188-3p that targets BACE1 was significantly downregulated both in the brains of AD

26 One of those genes (AtRALF23) is significantly downregulated by brassinolide (BL) trea

27 as significantly upregulated and hsa-miR-30c was significantly downregulated by Onconase treatment in

28 We found that OGG1 expression was significantly downregulated by the RUNX1-ETO fusion

29 ssion profiling identified seven miRNAs that were significantly downregulated by IL-6 overexpression

30 cribed non-canonical integrin beta3 pathway, were significantly downregulated by LSD1 silencing.

31 xisome profilerator-activated receptor gamma were significantly downregulated by TNF-alpha treatment.

32 ve voltage-gated fibroblast current (IKv,fb) was significantly downregulated (by ?44%), whereas the B

33 e AMP genes (DEFB1, DEFA5, DEFA6, and CAMP), was significantly downregulated compared to that of TNFA

34 RP2), a key factor for vascular development, was significantly downregulated during EC differentiatio

35 he structural neurofilament NF-H is found to be significantly downregulated following injury in both

36 In humans, LRP6 and Wnt signaling are significantly downregulated in AD brains, likely by

37 nes associated with each of these phenotypes are significantly downregulated in response to Dmel\Kdm4

38 or of apoptosis protein family, was found to be significantly downregulated in an inverse relationshi

39 We found FOXP1 to be significantly downregulated in both EZH2- and MEF2B-m

40 lon cancer, we found claudin-7 expression to be significantly downregulated in cancer samples.

41 iRNAs in blood in PTSD&Dep reveals miRNAs to be significantly downregulated in cases versus controls.

42 ed in healthy human ventricle and appears to be significantly downregulated in failing hearts.

43 OID CLEAVAGE DIOXYGENASE 8 gene was found to be significantly downregulated in SPL13 RNAi silencing p

44 00 calcium-binding protein A11 (S100/A11) to be significantly downregulated in the presence of IL-4 a

45 cells from DCIS tumors revealed that miR-140 is significantly downregulated in cancer stem-like cells

46 d in hematopoietic cells, and its expression is significantly downregulated in chronic lymphocytic le

47 protein of the CCN (CYR61/CTGF/NOV) family, is significantly downregulated in clinical samples of hu

48 or tight control of local RA concentrations, is significantly downregulated in embryos of diabetic mi

49 el regulatory system are shown as miR-515-5p is significantly downregulated in ER-positive (n = 146)

50 )-dependent protein kinase kinase 2 (CAMKK2) is significantly downregulated in individuals with schiz

51 induces an upregulation of p53; (ii) miR-124 is significantly downregulated in malignant prostatic ce

52 Here we show that miR-153 is significantly downregulated in maturation ameloblasts

53 We next show that RAB26 and RAB3D expression is significantly downregulated in Mist1(-)(/)(-) ZCs, su

54 The long noncoding RNA (lncRNA) MEG3 is significantly downregulated in pancreatic neuroendocr

55 Expression analysis indicated that KLF4 is significantly downregulated in prostate cancer cell l

56 sion of the Bmp4, Fgf10, Msx1 and Osr2 genes is significantly downregulated in the developing palatal

57 ox9 are significantly upregulated while Pax3 is significantly downregulated in the muscle progenitor

58 SMCs of the vascular wall and its expression is significantly downregulated in the vascular walls wit

59 L-6 and matrix metalloproteinase 3 secretion was significantly downregulated in activated FLS transfe

60 omosomal rearrangement, while its expression was significantly downregulated in another patient with

61 Here, we identified that miR-223 was significantly downregulated in chronically hypoxic m

62 MiR-146a expression was significantly downregulated in diabetic mouse wounds

63 further showed that Dkk4, a Wnt antagonist, was significantly downregulated in Fzd6(-/-) mice along

64 We previously reported that STAT1 expression was significantly downregulated in Gata1-knockdown murin

65 icate that the expression of NOTCH receptors was significantly downregulated in HLHS-iPSC-derived car

66 CLDN8 was significantly downregulated in IBD patients with inf

67 TLR3 was significantly downregulated in IEC in active CD but

68 miR-23a expression was significantly downregulated in macular RPE cells fro

69 evious miRNAome analysis showed gga-miR-219b was significantly downregulated in MDV-induced lymphoma,

70 expression (at both mRNA and protein levels) was significantly downregulated in neutrophils from seps

71 CIB2 was significantly downregulated in ovarian cancer and lo

72 We also found that miR-1296 was significantly downregulated in prostate cancer sampl

73 everse transcription-PCR revealed that WIF-1 was significantly downregulated in RCC samples and RCC c

74 Microarray analysis revealed that RORgammat was significantly downregulated in TCF-1(-/-) thymocytes

75 GABA(A) receptor clustering protein gephyrin was significantly downregulated in the BLA after fear ac

76 Interestingly, miR-205 expression was significantly downregulated in the brains of patient

77 e found that endogenous Osr2 mRNA expression was significantly downregulated in the developing tooth

78 lysis revealed that microRNA-193-3p (miR193) was significantly downregulated in the lung tissue and s

79 To this end, CCR7 expression by iDCs was significantly downregulated in tolerant mice and thi

80 AsFAR transcription levels were significantly downregulated in A. suturalis feeding

81 Expression levels of all 6 candidate miRNAs were significantly downregulated in blood of TCMVR patie

82 Collagen III and alpha-smooth muscle actin, were significantly downregulated in CXL HKCs.

83 , and CNN1, and endothelial cell marker CD31 were significantly downregulated in Drosha cKO mice comp

84 zed with glial glutamate transporters, which were significantly downregulated in ephrin-A2 KOs.

85 We found that DNMT1 and 3b levels were significantly downregulated in G(0)/G(1)while DNMT3

86 AKT2 and phospho-AKT levels were significantly downregulated in human thoracic AAD t

87 omoter activities of TGF-beta1 and -beta RII were significantly downregulated in KSFM compared with D

88 ere, we found that miR-218 expression levels were significantly downregulated in lung cancer tissues

89 We focused on mir-145 whose levels were significantly downregulated in malignant mesothelia

90 d, and a number of its putative mRNA targets were significantly downregulated in motor neurons after

91 iling displayed several important genes that were significantly downregulated in Myo-3M mice compared

92 Messenger RNA levels of SCO2 were significantly downregulated in myopic mouse retinae

93 gral transcriptional co-activator Pgc-1alpha were significantly downregulated in Ogg1(-/-) livers.

94 Dermally expressed genes were significantly downregulated in psoriatic biopsies,

95 proteins, which include p53, CHEK1 and BRCA1 were significantly downregulated in SZ.

96 We found 30 genes that were significantly downregulated in the dorsal horn of P

97 evealed that 18 of the 23 cytokines analyzed were significantly downregulated in the hemisphere contr

98 ransglutaminases (Tgms) and their substrates were significantly downregulated in the knockout mice.

99 mune response and inflammation-related genes were significantly downregulated in the omental adipose

100 important in extracellular matrix structure were significantly downregulated, including decorin, fib

101 In dry eye, 46 glycogenes were significantly downregulated, including five members

102 versely, the negative marker for MSCs, CD45, was significantly downregulated (median, -2.7).

103 , we find that two others, Ynl058c and Alk1, are significantly downregulated on DNA damage.

104 Moreover, vascular endothelial growth factor was significantly downregulated on ER alphaKO EPCs compa

105 ontrast, CDC42 and PAK1 messenger RNA levels were significantly downregulated specifically in deep la

106 beta-defensins tested, only beta-defensin 1 was significantly downregulated, suggesting beta-defensi

107 paralogs, miR-106a~363 and miR-106b~25, that are significantly downregulated upon syncytiotrophoblast

108 As miR-27b, miR-29b, miR-150, and miR-223 as being significantly downregulated upon CD4(+) T cell act

109 elevated temperature, the expression of LtpA was significantly downregulated when spirochetes were gr

110 omic analysis showed that ribosomal proteins were significantly downregulated whereas EMT-associated

111 Clinically, KLF14 transcription is significantly downregulated, whereas Plk4 transcripti

112 HSP-27 was significantly downregulated, whereas vimentin was up

113 th immune function and response to pathogens was significantly downregulated with the loss of RB.