ライフサイエンスコーパス: be specific for

1 Oxidation was specific for 11-cis-retinol and 9-cis-retinol.

2 T cell lines were specific for 15 immunodominant peptides and derived

3 HSV-1 glycoprotein B, whereas the other half are specific for 18 subdominant epitopes.

4 This effect is specific for 4-AP compared with its heterocyclic base

5 Both radioligands were specific for 5-HT7R, as binding could be blocked by

6 m CBir1 flagellin TCR transgenic mice, which are specific for a commensal Ag, increased intestinal pI

7 this protocol, ubiquitinated substrates that are specific for a given ligase can be isolated for mass

8 Vbeta5(+) regulatory T cells (Tregs), which are specific for a mouse endogenous retroviral superanti

9 SSCs, not many definitive markers exist that are specific for a rare subset of SSCs that self-renew a

10 y found in serum or cerebrospinal fluid that is specific for a cytosolic intermediate filament protei

11 ystalline state, the remote site in solution is specific for a divalent cation, binding both calcium

12 these demyelinating/axopathic autoantibodies is specific for a subset of patients with multiple scler

13 The test is specific for A-T, independent of the type of ATM muta

14 infection in mice, we demonstrate that LLPCs were specific for a single dominant neutralizing epitope

15 TCR Tg mice in which the CD4 T cells (CA30) were specific for a Vkappa peptide encoded by the kappaT

16 The 4 new risk loci for AAA seem to be specific for AAA compared with other cardiovascular d

17 gnetic resonance imaging contrast probe that is specific for Abeta oligomers.

18 gagement of Galphaq A representative peptide was specific for active Galphaq because it did not bind

19 Frank neuron loss in the entorhinal cortex is specific for AD, and related structural and functiona

20 AtGALT2 is specific for AGPs because substrates lacking AGP pept

21 (+) T cells in nonimmunized foster pups that are specific for Ags against which the foster dam was im

22 This inhibitory effect is specific for AICD through suppressing NFAT1-regulated

23 can be inhibited by MK2206, a compound that is specific for Akt.

24 cteristic motif at the N-terminus appears to be specific for Al-responsive ALMTs.

25 The probe is specific for ALKBH3 over its related homologue ALKBH2

26 The LC-MS/MS method was specific for all five tested SULTs, whereas Western

27 due to the binding of E. coli ORN 178, which is specific for alpha-mannoside.

28 Thus, GVOGEA is specific for alpha1beta1.

29 s, approximately 0.15% of renal CD4(+) cells were specific for alpha3IV-NC1.

30 These effects were shown to be specific for alpha4beta1 integrin and not other integ

31 This pathway, which is specific for alphavbeta6, because it is not regulated

32 attenuation of lung inflammation during ALI were specific for alveolar-epithelial expressed HIF1A.

33 In C57BL/6J mice, half of these cells are specific for an immunodominant epitope on HSV-1 glyc

34 tate kinetic analysis establishes the enzyme is specific for an intact steroid ring system versus hex

35 This inward vesiculation is specific for AnxA2 and not shared with other PI(4,5)P

36 at reducing Abeta production should ideally be specific for APP cleavage.

37 Enhanced learning was specific for appetitive tasks, as aversive learning

38 The effect was specific for ArfGAP3 and dependent on its GAP activi

39 hosphorylated substrates showed that AtPyrP2 is specific for ARPP.

40 permease mutants clearly show that CgAcr3-1 is specific for As(III).

41 EV source with a specific miRNA cargo, which are specific for ASH-related liver injury.

42 The MthRnl adenylation reaction is specific for ATP and either ssDNA or RNA.

43 tion of mCD8alpha:chIgalpha-expressing cells was specific for B cells and required active signaling d

44 The association of beta-Pix and SNX27 is specific for beta-Pix isoforms terminating in the typ

45 This defect was specific for beta1 integrins, as adhesion and polari

46 The imaging findings were found to be specific for bilateral non-gestational pure primary o

47 ost cells tested, whereas pathway y1869-1873 was specific for binding to macrophages.

48 The inhibitory activity was specific for blue light, and the inhibiting light wa

49 believe to be modulated by oxytocin, may not be specific for borderline personality disorder but rath

50 ical blood flow with tvortex less than 14.3% was specific for borderline mPAP.

51 However, these binding sites are specific for both cholesterol and beta2AR, as shown

52 The results of this study are specific for breath-hold perfusion CT of HCC and may

53 lonal antibodies, only two unique antibodies were specific for C-PfCSP, highlighting the rare occurre

54 rences between GLTP superfamily members that are specific for C1P versus glycolipid.

55 did not occur in CA1, suggesting this effect is specific for CA2.

56 eria and features of fusion transcripts that are specific for cancer.

57 Bacterial AlkC and AlkD are specific for cationic alkylated nucleobases and have

58 CCR5 antagonists, Schering-C (SCH-C), which is specific for CCR5, and TAK-779, a dual inhibitor of C

59 The Cas6-1 subtype is specific for CD-family CRISPR repeats, generating crR

60 This effect was specific for CD4 T cells, as memory CD8 T cells surv

61 ikingly, the in vivo regulatory role of Gfi1 was specific for CD8(+), and not CD4(+) T cells or immat

62 tion of ACD11, a lipid transfer protein that is specific for ceramide 1-phosphate (C1P) and phyto-C1P

63 g of Hsp90, Hsp70, and CHIP in a manner that is specific for changes in the heme/substrate binding cl

64 Anserine was found to be specific for chicken intake, whereas trimethylamine-N

65 nnel in lipid membranes and that the channel is specific for chitooligosaccharides.

66 ly 25% of synovial IgG-expressing B cells to be specific for citrullinated autoantigens in the invest

67 the development of precision medicines that are specific for clinical targets.

68 nsplants not only increase over time without being specific for CNI toxicity but are affected by samp

69 Activity assays indicate that sCoaT is specific for Co(2+).

70 rating that the effects of tat-cyclotraxin-B are specific for cocaine reinforcement.

71 om human butyrylcholinesterase (BChE), which is specific for cocaine hydrolysis, and obtain a much hi

72 antiproliferative effect was demonstrated to be specific for compound 19, endowed with the best combi

73 This reciprocal relationship is specific for copper, indicating that cell necrosis is

74 Of the one third of these transcripts that were specific for CRPC, we defined a novel lncRNA termed

75 PSCu10 is specific for Cu(2+), and it has no cleavage in the pr

76 difficulty in developing an immunoassay that is specific for D-dimer arises from the inherent heterog

77 The resulting assay was specific for d-(+)-maltose versus other sugar analog

78 We concluded that IgE was specific for D-[Asp/Glu], not D-Asp or D-Glu, and th

79 This adaptation persisted for 3-4 d, was specific for DA neurons of the VTA, and occurred in

80 Transport effects were specific for DA mitochondria, which were smaller an

81 e sensitivity to amino-terminal substitution was specific for DAT, because replacing the SERT N and/o

82 s finding suggests that the OB domain, which is specific for DEAH/RHA helicases, plays an important r

83 The FISH probes were specific for detection of HMPV positive-sense RNA (

84 ther these effects are ubiquitous or if they are specific for different cognitive systems.

85 nomenon, which remain to be clarified, could be specific for different GPCRs.

86 iquitin conjugates, half of which prefer, or are specific for, DIX54-Ub, including Cezanne and CYLD.

87 By using primers that are specific for DNA methylation patterns in beta cells,

88 This defect is specific for DNA molecules because inactive mutants f

89 HWTX-IV is specific for domain II, and we identify five residues

90 Patients' antibodies were found to be specific for DPPX, without reacting with DPP10 or Kv4

91 homotypic interactions between epitopes that are specific for each subgroup of patients with homogene

92 hich identifies the two free parameters that are specific for each subject.

93 m-property with a complex genetic basis that is specific for each chromosomal locus, and it can be in

94 is provided in different contexts, learning is specific for each context.

95 onsensus slopes of the calibration lines and is specific for each signal produced by a well-defined s

96 This effect is specific for EGFR versus other Hsp90 client proteins.

97 at observed in the activating complexes, yet is specific for eIF4AIII.

98 T cells from the HIV-coinfected cohort that were specific for epitopes of HCMV phosphoprotein-65, te

99 erformed to determine whether tracer binding was specific for ERs.

100 e sera were seen in IFA but were resolved to be specific for established HCoVs by discriminative test

101 rthologue) as a central assembly factor that is specific for established MKS module components and de

102 ardiac uptake of the PET tracer (18)F-FBzBMS is specific for ET-A expression in rats, shows infarct-r

103 a profound decline in serum antibodies that were specific for exogenous antigen or DNA, frequencies

104 known whether such an interconnected network is specific for faces or whether there are similar netwo

105 enotype of microsatellite signal instability is specific for FANCJ apart from the intact FA pathway,

106 s to be determined whether these alterations are specific for fatigue or whether they relate to other

107 defect is observed in TTD and not in XP and is specific for fibroblasts, which are the main producer

108 The effect is specific for FLT3-mutant cells and is ascribed to the

109 The sensing is specific for fluoride among various other anions.

110 in this range of concentrations, rubreserine was specific for folate biosynthesis.

111 ber of neurons, choice-differential activity was specific for free, internally generated economic cho

112 mocortical circuits and whether this deficit is specific for frontal regions.

113 This effect was specific for glucocorticoids and dependent on the gl

114 nditions (KD = 2.1-5.7 muM) and that binding is specific for Grb7-SH2 over closely related domains (l

115 ons, 68/69 were confirmed by blotting, which was specific for greater than 275 repeats.

116 ed a synergistic tumor killing activity that was specific for HCC in HBx transgenic mice.

117 D) to determine whether any observed changes were specific for HD.

118 ant for cell growth and division rather than being specific for hematopoiesis.

119 (+) BC into low and high-risk subgroups, and was specific for HER2(+):estrogen receptor alpha-negativ

120 This anxiolytic effect was specific for high anxiety as MitoQ treatment did not

121 diatric population, marked hyperferritinemia is specific for HLH.

122 tibody antigen-binding fragments (Fab), that is specific for HT-2 toxin and has a positive readout.

123 8 receptor antagonist domain Abs (dAbs) that are specific for human CD28.

124 fH downregulation of the AP via fHbp or NspA is specific for human fH.

125 t to other Src kinases, and this interaction was specific for human but not mouse proteins.

126 This unique repair function of Mph1 is specific for ICL damage and does not extend to other

127 This enhancement is specific for IL-17A but not for IL-17F, IL-22, and CC

128 Transcriptional silencing was specific for IL-1beta because expression of other pr

129 nclude the development of nanomaterials that are specific for immune cell subsets and can be used as

130 ric and/or cooperative effects as the latter are specific for individual cases only.

131 we have gained into treatment paradigms that are specific for individual phenotypes of achalasia and

132 The emerging parietal representation is specific for individual episodes of experience, predi

133 Inhibition is specific for influenza virus, as inhibition of Sendai

134 cKL activity in vitro was specific for interactions with FGF23 and was FGFR de

135 rated that the SusC and the MFS transporters are specific for internalization of linear xylo-oligosac

136 This is specific for iTreg development, because frequency of

137 e influenza A virus strains and confirmed to be specific for its intended subtype.

138 downstream kinase activation by alphavbeta6 is specific for JNK1, with no involvement of p38 or ERK

139 This interaction is specific for K(V)10.1 and does not occur with K(V)10.

140 The imaging findings were found to be specific for Kimura disease.

141 This effect is specific for Kv1.1 because coexpression of Kv1.4 chan

142 The identified conserved complex might be specific for leaf growth in the second dimension, sin

143 the typical type II CHIs currently known to be 'specific' for legume plants.

144 The imaging findings were found to be specific for leiomyomatosis peritonealis disseminata

145 ly established LTK ligand FAM150A (AUG-beta) is specific for LTK and only weakly binds to ALK.

146 termining region Y-box 11 (SOX11) expression is specific for mantle cell lymphoma (MCL) as compared w

147 Wnt2-Wnt7b cooperation is specific for mesenchymal cell lineages and the combin

148 Here we define a pathway that is specific for METTL3 and is implicated in the maintena

149 These effects are specific for Mfn2, as the loss of Mfn1 yielded no co

150 bleeds on in vivo magnetic resonance imaging are specific for microhaemorrhages in cerebral amyloid a

151 288K variant show that its mutator phenotype is specific for misincorporating opposite template A up

152 and diffusion-tensor MR imaging alterations were specific for motor neuron disease phenotypes, with

153 The hydroxamates were specific for MPO in neutrophils and more potent tow

154 r proper RBC morphology, and that the effect is specific for MPP1.

155 ncated peptide (SSTNIGF1R-T) that appears to be specific for multiple myeloma cells.

156 nal patterns for month of birth suggested to be specific for multiple sclerosis (increased in the spr

157 re normally exclusively expressed in HSCs or are specific for multipotent progenitors and erythropoie

158 It was confirmed to be specific for Mycobacterium bovis and M.caprae cells.

159 ding evidence that the IatP-IatA transporter is specific for myo-inositol.

160 nthesis since the A domains of MbtE and MbtF are specific for N(6)-acyl-N(6)-hydroxy-l-Lys and N(6)-h

161 It is specific for Na(+) over K(+), and it is not exhibited

162 utination assay (CSF-TPHA) titer of >/=1:640 is specific for neurosyphilis diagnosis.

163 their surface, a marker that was thought to be specific for NK cells and associated with cytolytic e

164 Three of the TIL TCRs were specific for non-mutated self-antigens, two of whic

165 All sdAb were specific for NP and those tested required the C-ter

166 eurological disease severity and appeared to be specific for NPC1.

167 that none of the new HCV helicase inhibitors were specific for NS3h.

168 all five tested SULTs, whereas Western blot was specific for only two isoforms.

169 we identified multiple genomic regions that are specific for, or absent from, type III strains compa

170 tment, olfactory marker protein (OMP), which is specific for ORNs, was not detected in nasal lavage s

171 etermine whether the phosphorylation changes were specific for osmosignaling or involved cross talk w

172 ng interferon responses in monocytes and DCs is specific for p30, and represent an essential early st

173 Moreover, these effects were specific for pain, as self-report and ERP measures

174 The emitted signal was specific for PARP1 expression and, most importantly,

175 The cytotoxicity of the VIP derivatives is specific for pathogens, because they do not affect th

176 roadly applicable conjugation chemistry that is specific for Pcl and orthogonal to all other reactive

177 effect is absent in LPS-activated cells and is specific for PGE2 because it cannot be reproduced by

178 s is catalyzed by PHEOPHYTINASE (PPH), which is specific for pheophytin (i.e. magnesium-free chloroph

179 ereas the transporter at blood brain barrier is specific for phospholipid form of DHA.

180 The effect of PriB is specific for PriA-PAS association, but not for PriA-d

181 The similarity was specific for promoter regions and cerebellum and fro

182 we highlight that increased serum ATX levels are specific for pruritus of cholestasis, but not prurit

183 This current decrease is specific for PSA above a limit of quantification in t

184 A newly identified NB predicted to be specific for Pseudomonas aeruginosa (pyocin Sn) was p

185 nt genetic alteration in thyroid cancers and is specific for PTC, characteristics that make it the mo

186 This inhibition of G(q) signaling was specific for PTHR signaling, compared with other G(q

187 Low serum erythropoietin (EPO) values were specific for PV, but normal EPO values were found a

188 The reduction in glucose production was specific for pyruvate; glucose production from glyce

189 This effect was specific for RA because control cells showed opposit

190 EHop-016 is specific for Rac1 and Rac3 at concentrations of </=5

191 Akt-mediated activation in macrophages was specific for Rac1 because Akt did not increase activ

192 are guanine nucleotide exchange factors that are specific for Ras or Rap, and are important regulator

193 This observation was specific for RASFs as a reverse behavior was observe

194 ligase seven in absentia homolog (SIAH) that is specific for regulation of protesome-dependent DCC de

195 enhancer of CCND1 (encoding cyclin D1) that is specific for renal cancers characterized by inactivat

196 ults show that one of the nitrate reductases is specific for respiration and denitrification while th

197 Matrilin-1 and epiphycan were specific for rib and trachea, whereas asporin was p

198 etects all tested Rickettsia spp.; the other is specific for Rickettsia rickettsii.

199 ass 1 RNA pseudoknots, such as aptamer T1.1, are specific for RTs from only a few viral clades.

200 is catalyzed by allantoinase, an enzyme that is specific for (S)-allantoin, an allantoin racemase is

201 NK cells lacking KIRs that are specific for self HLA are therefore "unlicensed" and

202 Ssu72 is unique in that it is specific for Ser(P)(5) in one orientation of the CTD

203 activity-based probe (fluorophosphate) that is specific for serine hydrolases.

204 xpress Valpha2/Vbeta5 regions of the TCR and are specific for SIINFEKL peptide (chicken ovalbumin (OV

205 nt has raised hopes for therapies that would be specific for single-gene disorders and identify cellu

206 g, electrograms that exhibit MES and PMI may be specific for sites critical to reentry.

207 This effect was specific for slow wave activity, and not for sleep d

208 results show that ligand decorated liposomes are specific for Sn, since they are taken up by bone mar

209 This modulation of theta rhythmicity, which was specific for social stimuli, appeared to reflect a b

210 Other product ions were found to be specific for some structures.

211 Both BvhAT and BvhATpin transposons are specific for species of the genus Beta and closely r

212 similar pattern of down-regulated genes that are specific for spermatogenesis between the two hybrids

213 zation required NMDA receptor activation and was specific for stimuli that induced LTP.

214 rculating HIV-1 isolates while antibody 2909 is specific for strain SF162.

215 ies revealed that the antigenic lipopeptides are specific for strains of the M. tuberculosis complex.

216 d from two components (PlyCA and PlyCB) that is specific for streptococcal species.

217 nd Glu; and (iii) that some isoforms of Ate1 are specific for substrates bearing N-terminal Cys resid

218 rning per se, we here show that D2 receptors are specific for support of a consolidated form of odor

219 re surprisingly few distinct chemotypes that are specific for SUR1-containing KATP channels.

220 as HLA class I hyperexpression and insulitis were specific for T1D and persisted in a small portion o

221 but it is challenging to find peptides that are specific for targeted pests.

222 equires glucose monomycolate (GMM) antigens, is specific for TCR structure, and is blocked by a recom

223 The biosensor is specific for Tdp1 even in complex biological samples,

224 The biosensor was determined to be specific for TGF-beta1 with an experimental detection

225 tor-binding subunit and the remaining fourth are specific for the assembled glycoprotein complex, req

226 lude the genes encoding inhibitory KIRs that are specific for the C1 and C2 epitopes of HLA-C.

227 ddition, we analyzed those alterations which are specific for the combination of both stresses.

228 Recently developed antibodies that are specific for the complex of the prototypical invaria

229 Some of the package functions are specific for the domestic dog (Canis familiaris) dat

230 High-affinity interactions with MED25 are specific for the ETV1/4/5 subfamily as other ETS fac

231 king advantage of the types of queries which are specific for the high-throughput molecular profiling

232 nsgenic mice in which >98% of CD8(+) T cells are specific for the immunodominant HSV-1 epitope (gBT-I

233 that aid RNAP during the transcription cycle are specific for the individual domain or only conserved

234 novel nonlipid and drug-like compounds that are specific for the LPA(2) receptor subtype.

235 Although beta-agarases are specific for the neutral agarobiose moieties, the re

236 d from humans with previous dengue infection are specific for the nonstructural and the prM structura

237 s by the major stromal molecular motor Hsp70 are specific for the physicochemical properties of the T

238 tructure and that some of these correlations are specific for the pre-diabetic state.

239 fined conditions show that TRIM32 and TRIM25 are specific for the Ubc5 family of E2-conjugating prote

240 croscopy revealed that AtTIP1;3 and AtTIP5;1 are specific for the vacuoles of the vegetative and sper

241 it might be important for the RPE signal to be specific for the action that led to that error.

242 This assay was found to be specific for the detection of EBOV, as no nonspecific

243 cyclovir, a nucleoside analog, is thought to be specific for the human herpesviruses because it requi

244 Here we show that Tfr cells can be specific for the immunizing antigen, irrespective of

245 ht-related responses, 87 genes were found to be specific for the response of young developing leaves

246 These antibodies were found to be specific for the same, presumably single, non-MHC ant

247 The assay was demonstrated to be specific for the target bacteria when compared with o

248 the MassMatrix algorithm) was designed that is specific for the analysis of glycopeptide anions by U

249 man chimeric IgE antibody (MOv18 IgE), which is specific for the cancer-associated antigen folate rec

250 tional knockout, using Hoxb7-driven Cre that is specific for the collecting ducts and a subset of dis

251 s to a similar monooxygenase, CYP92C6, which is specific for the conversion of (E,E)-geranyllinalool

252 MlghC is specific for the double C3/C5 epimer generated by Mlg

253 trand breaks observed with TOT treatment and is specific for the EpRE-containing region of the QR gen

254 the FSC lineage, and that Wingless signaling is specific for the FSC niche whereas Hedgehog signaling

255 The recombinant mAb 131 is specific for the gamma-subunit of the fetal AChR to w

256 This effect is specific for the GluA2 subunit of the AMPAR and requi

257 Transgenerational inheritance of lifespan is specific for the H3K4me3 methylation complex and is a

258 genetic manipulation of SRC-2 in this study is specific for the heart and thereby eliminating potent

259 The resulting hydrophobic moment vector is specific for the instantaneous conformation, and it t

260 We generated a CAR that is specific for the kappa light chain (kappa.CAR) and th

261 vered a new polysaccharide lyase family that is specific for the l-rhamnose-alpha1,4-d-glucuronic aci

262 ropin releasing hormone, and an agonist that is specific for the mutant.

263 O-1) and end-binding protein-1 (EB-1), which is specific for the plus end of microtubules demonstrate

264 3-triggered wave of cell mitosis after birth is specific for the retinal DA cells.

265 es not contain the conserved sequence motif, is specific for the rRNA binding site of S8.

266 MspJI is specific for the sequence 5(h)mC-N-N-G or A and cleav

267 phoethanolamine or glycerophosphocholine and is specific for the sn-2-deacylated form of plasmalogen.

268 indicates that the entry to the binding site is specific for the sugar-phosphate backbone and/or conf

269 ,3)-Gal and have demonstrated that the ELISA is specific for the target and can be used to determine

270 tinates human blood group A erythrocytes and is specific for the unique glycan N,N'-diacetyllactosedi

271 cating that the effect of helix 12 extension is specific for the vesicle-priming step.

272 We demonstrate that omptin cleavage is specific for the Y. pestis and Y. pseudotuberculosis

273 The targeted neuronal ensemble was specific for the cue-induced response because stress

274 The biosensor was specific for the detection of synthetic AbetaO and g

275 BioC was specific for the malonyl moiety and was inhibited by

276 ded dominance in the caudomedial nidopallium was specific for the song-learning phase and was memory-

277 for retrieval of the memory, and the memory was specific for the spatial pattern of neurons artifici

278 The assay was specific for the targeted bacteria when investigated

279 DNA methylation activity was specific for the targeted region and heritable acros

280 The sensitizing effect of Poly I:C was specific for the TLR-3 pathway because mice deficien

281 Tolerance induction was specific for the tolerogenic vaccine Ag PLP178-191 o

282 erestingly, the impairment in LTP in KO mice was specific for the type of LTP that depends on the neu

283 ing from the progressive engineering process was specific for the XID mutant allele versus the wild-t

284 01, CD8(+) T cells that expressed CD45RA and were specific for the pp65 protein (NLVPMVATV epitope) h

285 independent of transcription, and appears to be specific for these membrane proteins.

286 The regulation of beta-catenin by GSKIP is specific for this AKAP as AKAP220, which also binds P

287 n ( approximately 30% of splenic CD8 T cells were specific for this peptide at the peak of the respon

288 both HREC and abiotic surfaces, Com control was specific for those structures produced on HREC.

289 es, and IgG eluted from one of these samples was specific for THSD7A.

290 n of selected high-risk sonographic features was specific for thyroid malignancy.

291 cy of CD73-expressing immune cells seemed to be specific for TLR9 deficiency and was MyD88 independen

292 nthesis, their AspRS enzymes were thought to be specific for tRNA(Asp).

293 s II-restricted CD4(+) T-cell responses that are specific for tumors.

294 r serendipitous discovery that this activity was specific for tyrosine in vitro, and how this in turn

295 Of these, Phep_2830 is known to be specific for unsaturated heparin disaccharides.

296 enes with distinct expression patterns: some are specific for vestibular hair cells, others for cochl

297 nd N-cadherin, the effect of TRPM7 silencing was specific for vimentin protein expression and STAT3 p

298 -violent offenders, indicating that findings were specific for violent offending, and not largely att

299 While 10 findings thought to be specific for whiplash trauma were significantly (P<.0

300 n-fusion events, suggesting that this effect is specific for Wnt-5a alone.