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1 expression within the PTEN-null fibroblasts was sufficient to abrogate the observed increase in colo
3 Introduction of the shed ectodomain of NgR1 is sufficient to accelerate excitatory synapse formation
5 ded to test whether passive mechanisms alone are sufficient to account for the aggregate distribution
6 uid, and hence of the mobile repair factors, is sufficient to account for the extent of DNA damage an
7 by the present findings, we conclude that PS is sufficient to account for the perceptual organization
8 Simply knowing which neurons were activated is sufficient to accurately represent odor identity, wit
9 s model that 4 weeks of triple therapy could be sufficient to achieve SVR in patients with undetectab
10 y probed via second harmonic generation that is sufficient to achieve d33>10 pm V(-1), when incorpora
11 ngs, but it is unclear whether this approach is sufficient to achieve universal coverage of HIV testi
13 rone data and showed that small sample sizes were sufficient to achieve 80% power (16, 47, and 25 pat
14 es containing 2-3 nmol Cl injected on-column were sufficient to achieve a precision (sigma) of 0.1 mU
15 in pre-malignant B cells, Myc overexpression is sufficient to activate BCR and PI3K/Akt signaling pat
19 expression of relatively few genes, but this is sufficient to adjust the configuration of the respiro
20 process understanding and data availability is sufficient to advance with incorporating management i
22 clude that even minute levels of active AADC are sufficient to allow for substantial amounts of dopam
23 h is normally restricted to tight junctions, is sufficient to alter apical membrane identity through
24 t loss of FLG in the absence of inflammation is sufficient to alter the expression level of proteins
25 ether enhancing the activity of AgRP neurons is sufficient to attenuate fertility in vivo, we artific
27 apacity, while induction of cytosolic Ca(2+) is sufficient to attenuate thermogenic gene expression,
28 monstrated that selective hair cell ablation is sufficient to attract leukocytes into the spiral gang
30 e DNA and co-repressor binding domains alone are sufficient to avoid Rett syndrome-like defects and m
31 oughout the bead structure ( 150mg/mL) which is sufficient to be imaged under standard fluoroscopy an
32 s, precisely targeted at the decision point, were sufficient to bidirectionally influence impulsive c
35 15, restricts HCMV replication, and that IE1 is sufficient to blunt ISGylation in response to dsDNA s
36 dictates nuclear rigidity, and modulating it is sufficient to both induce and suppress nuclear blebs.
38 tably, artificial targeting of Fun30 to DSBs is sufficient to bypass the cell cycle regulation of lon
39 changes in corticosterone levels in chickens are sufficient to cause a specific change in decision ma
40 ubtle changes in the activity these channels are sufficient to cause devastating inherited neurologic
41 nel recognised that Zika virus alone may not be sufficient to cause either congenital brain abnormali
42 oprotein, but not a fusion defective mutant, is sufficient to cause CO2 sensitivity, which can occur
44 ned activation of EGFR in proximal epithelia is sufficient to cause spontaneous, progressive renal tu
45 emonstrate that an increase of SERT activity is sufficient to cause the apneas in Necdin-KO pups, and
46 nce that HMGB1 infusion into the hippocampus was sufficient to cause anhedonic behavior and by eviden
47 id degradation or fatty acid oxidation alone was sufficient to cause defective differentiation, while
48 confirmed that a Gln201Arg mutation in Wag31 was sufficient to cause resistance to APYS1, however, ne
51 ion and accumulation of NADPH to levels that are sufficient to combat oxidative stress in cancer cell
52 nd hypothesize that RNA bound to Tyr-315 may be sufficient to competitively inhibit ssDNA deaminase-d
54 transgenic zebrafish model to show that Myf5 is sufficient to confer tumor-propagating potential to R
56 3 into the susceptible wheat variety Fielder was sufficient to confer resistance to Ug99, confirming
58 future studies in FL and DLBCL, with 800 mg being sufficient to consistently achieve durable respons
59 toisomerization at the GluN1 clamshell hinge is sufficient to control glycine sensitivity and activat
61 BChl c; however, it is unknown whether BciD is sufficient to convert BChl c (or its precursor, bacte
62 gamma-tubulin ring complex (gamma-TuRC), and is sufficient to convert mitochondria to MTOCs independe
63 mary, MC3Rs expressed in Nkx2.1(+ve) neurons are sufficient to coordinate hypothalamic response and e
65 ological receptor-ligand pairs on the T cell are sufficient to create spatial organization at membran
67 g lipogenesis in cultured liver cancer cells is sufficient to decrease cell viability; however, it is
69 mutation in its ER-interacting LxxLL motifs was sufficient to delay tumor onset and to impair tumor
70 A one-dimensional array of these devices was sufficient to demonstrate an efficient Hamming dista
71 etre square quadrats (i.e. 25 x 25 m) should be sufficient to detect B. pseudomallei at a given locat
72 at a CCS-based resolving power of >300 that is sufficient to differentiate analyte ions with CCS dif
73 gnments of non-solvent-exchangeable protons, are sufficient to direct a DMD search for low-energy RNA
74 sions possessing minimal RNA residues, which are sufficient to direct specific nuclease activity in v
76 the notion that deficiencies in specific SGs are sufficient to disrupt normal cell function and point
78 RNAi-mediated blockade of AKT, HSF1 or HuR is sufficient to downregulate Rictor and inhibit GBM gro
80 anscriptional activator to an enhancer would be sufficient to drive target gene expression, even if t
81 the soma of CA2 compared with CA1 PNs, which is sufficient to drive action potential output from CA2
83 idence that its genetic inactivation in mice is sufficient to drive acute myeloid leukemia.Significan
84 It is not known whether cell proliferation is sufficient to drive epithelial cell migration during
85 In mouse urothelial organoids, PPAR agonism is sufficient to drive growth-factor-independent growth
86 ear receptor NR4A1 in rhabdomyosarcomas that is sufficient to drive high expression of PAX3-FOXO1A th
89 7-associated transcription factor RORgammat, is sufficient to drive switching of Th17 cells towards a
90 lular matrix during mesenchymal condensation is sufficient to drive tissue folding along programmed t
91 ta suggest that a small pool of active EGFRs is sufficient to drive tumorigenesis by signaling primar
92 naling through one of its receptors, Ptger4, was sufficient to drive a differentiation state morpholo
93 ining Braf(V600E) activation with Trp53 loss was sufficient to drive both ICC hyperplasia and formati
94 itical component of the BM microenvironment, was sufficient to drive hematopoietic aging phenotypes i
95 IST, we observed that Braf(V600E) activation was sufficient to drive ICC hyperplasia but not GIST tum
97 he test compound and 100 mug/mL of the probe were sufficient to effectively monitor the generation of
99 shortening in NOTCH1-haploinsufficient mice is sufficient to elicit age-dependent cardiovascular dis
100 s indicate that induction of SAUR expression is sufficient to elicit auxin-mediated expansion growth
101 erm antiretroviral therapy (ART) and may not be sufficient to eliminate reactivated latently infected
104 hibition alone, but not combined inhibition, is sufficient to enhance AML drug sensitivity, which pro
106 dless of urease production by this organism, was sufficient to enhance P. mirabilis urease activity a
107 assumed that the elimination of visual input was sufficient to enhance plasticity in the adult mouse
112 g during the first week of a growth stimulus is sufficient to ensure long-term myofiber hypertrophy.
113 the amount of autonomy residents do achieve is sufficient to ensure readiness for the entire spectru
115 demonstrates a central integration mechanism is sufficient to evoke painful thermal TCE, an essential
117 xpansion of intestinal Enterococcus faecalis is sufficient to exacerbate ethanol-induced liver diseas
118 hus, three hijackings of regulatory elements are sufficient to explain all aspects of the complex exp
119 h slight barrier lowering, these two effects are sufficient to explain the observed emission current
120 and the antibiotic-target complex half-life are sufficient to explain which treatment strategy is mo
121 ine residue on the DIV S2 helix was found to be sufficient to explain Pre1a's potent and selective in
122 re, we show that mixing between water masses is sufficient to explain the observed distribution of DO
123 f Pol III in the gut of adult worms or flies is sufficient to extend lifespan; in flies, longevity ca
126 A17 and the capsid-like scaffold protein D13 was sufficient to form similar ER-associated viral struc
127 mice, but IDH1 overexpression in these cells was sufficient to fully restore chemoresistance under lo
128 able to initiate the APR to brain injury and are sufficient to generate the associated sickness behav
129 cuitoids of purified excitatory interneurons were sufficient to generate oscillatory bursts with prop
130 A template preparation and RNA transcription are sufficient to give M2-seq helix signatures; these si
131 ether differences between the two treatments were sufficient to guide clinicians in their choice of o
132 that very short strings of, i.e., 10 items, are sufficient to have their complexity reliably estimat
133 orrelations appearing during evolution alone are sufficient to identify key aspects of this design.
134 ate that the accuracy of the combined method is sufficient to identify misassignments and suggest rev
136 ction of PMN-MPs into wounded colonic mucosa was sufficient to impair epithelial wound healing in viv
138 at short-term induction of Drp1, in midlife, is sufficient to improve organismal health and prolong l
139 te whether increased endogenous SL transport is sufficient to improve plant nutrition and productivit
140 grade desiccation tolerance, and these genes are sufficient to increase desiccation tolerance when ex
142 oreover, a monomeric-only mutant form of Bax is sufficient to increase lysosomal membrane permeabilit
143 ic using closed-loop optogenetic stimulation is sufficient to increase movement in the TST in stress-
144 s of one allele of TSC2 in human fibroblasts is sufficient to increase p53 levels and impair stem cel
145 mes by pharmacologically slowing endocytosis was sufficient to increase arrestin-mediated signaling b
146 he control of a guard-cell-specific promoter was sufficient to increase stomatal sensitivity to ABA a
149 st that subarachnoid clots in sulci/fissures are sufficient to induce spreading depolarizations and a
150 We find that localized mechanical forces are sufficient to induce the formation of transcellular
151 Furthermore, ectopic expression of Pt-Ets4 is sufficient to induce cell delamination and migration
153 form of KRAS (KrasG12D) in pancreata of mice is sufficient to induce formation of pancreatic intraepi
155 In primary human monocytes, where LPS alone is sufficient to induce mature IL-1beta, PGE2 boosted LP
156 an adenoma-like colonic epithelial cell line is sufficient to induce metabolic and gene expression pr
159 induced EndoMT in vitro, Hey2 overexpression is sufficient to induce phenotypic conversion of endothe
161 expression of Fat4 and Ds1 in the same cells is sufficient to induce polarization of Fat4-Ds1 complex
162 brief-burst activity in glutamatergic fibers is sufficient to induce postsynaptic AP firing in the ab
164 molecule ligand to show that MLKL activation is sufficient to induce the processing and release of bi
166 mRNA downregulation, only disruption of Myh6 was sufficient to induce a cardiac phenotype, irrespecti
174 Ps compared with those in control tissue and were sufficient to induce OSM production (P < .001) in p
175 tions observed during Amazon biomass burning were sufficient to induce severe adverse effects in huma
177 pharmacologic targeting of SPHK1 or YAP/TAZ was sufficient to inhibit neuroblastoma metastasis in vi
180 ajb1-Prkaca fusion gene in wild-type mice to be sufficient to initiate formation of tumors that have
181 ates that activation of the Nrp2 gene in MCs is sufficient to instruct their circuit formation from t
182 t brief activation of STN projection neurons was sufficient to interrupt or pause a self-initiated bo
184 based application to multiple chemicals, may be sufficient to justify the cost for some applications
185 ng synchrotron x-ray diffraction and that it is sufficient to kill S. aureus These results suggest th
187 stridia added to mouse infant gut microbiota are sufficient to limit colonization of pathogenic Enter
188 positive and negative FDS on visual signals is sufficient to maintain a diversity of morphs displayi
189 ctron flow through the cytochrome bd oxidase is sufficient to maintain respiration and ATP synthesis
190 sine triphosphatases (GTPases) Rab4 or Rab11 was sufficient to maintain GJs upon elevated IIS in cult
191 associated virus-short hairpin RNA construct was sufficient to markedly and persistently elevate inge
192 nally and to circadian centers in the brain, are sufficient to mediate both of these developmental pr
195 t beta2AR signaling in the airway epithelium is sufficient to mediate key features of the asthmatic r
196 l module of Arabidopsis phytochrome B (PHYB) is sufficient to mediate the degradation of PIF3 specifi
197 at transformation of additional HEI10 copies is sufficient to more than double euchromatic crossovers
198 c silencing of HA neurons during wakefulness is sufficient to not only impair arousal but to rapidly
200 find that mSWI/SNF (BAF) complex recruitment is sufficient to oppose Polycomb within minutes, leading
202 re, we show that a fragmented draft assembly is sufficient to perform mapping-by-sequencing in nonmod
203 tion following early-life pheromone exposure are sufficient to permanently enhance specific avoidance
204 nthesized IFN-beta helix 4 and found that it is sufficient to permeate model prokaryotic membranes us
206 surement of five metabolites of the pathways was sufficient to predict the Vineland score with an R2
207 lishing immune homeostasis, but they may not be sufficient to prevent tissue-specific autoimmune dise
208 lation study suggests that spatial structure is sufficient to prevent antisocial rewarding from deter
211 t, as treating an average of only 50 zygotes is sufficient to produce a correctly targeted allele in
212 e than 1000 effective sequences the accuracy is sufficient to produce accurate models of proteins as
213 , Wnt inhibitor, and Gsk3 inhibitor (GiWiGi) is sufficient to produce cells expressing epicardial mar
214 the admixture, showing that a few centuries is sufficient to produce detectable genetic structure in
215 ily visible stimulus being viewed by one eye is sufficient to produce shifts in subsequent predominan
216 Here we show that eight synthetic genes are sufficient to promote filament assembly and that the
218 factors Wnt2b, Gremlin1, and R-spondin1, and are sufficient to promote maintenance of Lgr5(+) IESCs i
219 d line spacing, we show that a 2-mum spacing is sufficient to promote cell shape elongation and migra
220 Genetic experiments show that ectopic dATM is sufficient to promote DNA synthesis in wild-type fat
222 we show that Arabidopsis thaliana HAP2/GCS1 is sufficient to promote mammalian cell-cell fusion.
224 -N-AS, SK-N-BE2, and SH-SY5Y), soluble HBEGF is sufficient to promote neuroblast differentiation and
225 te that myeloid-specific deficiency of PTP1B is sufficient to promote the development of acute myeloi
226 sion from the HRAS locus; repression of HRAS is sufficient to promote the transition of quiescent cel
227 ssion of RAGE on human prostate cancer cells was sufficient to promote bone marrow homing within a sh
228 of PGBD5 in primary immortalized human cells was sufficient to promote cell transformation in vivo.
229 , or pharmacological inactivation of EHMT1/2 was sufficient to promote pathological hypertrophy and f
231 , but not any of these kinases individually, is sufficient to protect neurons potently from degenerat
233 ter vaccination, and a single dose of 50 mug was sufficient to protect non-human primates against a c
234 gyrus of presymptomatic adolescent hAPP mice was sufficient to protect these mice from developing cog
235 adipose tissue from previously infected mice was sufficient to protect uninfected mice from lethal pa
236 infections have shown that antibodies alone are sufficient to provide broad protection against diver
237 ets are functionally competent in vitro, and are sufficient to provide enhanced protection to infecti
238 , fusion of short fragments of EWSR1 to FLI1 is sufficient to recapitulate BAF complex retargeting an
239 2 and MMP-9 pharmacologically or genetically is sufficient to recapitulate transient synaptic potenti
240 n untransformed epithelial cells using siRNA was sufficient to recapitulate the increased motility an
241 malities or GBS but agreed that the evidence was sufficient to recommend increased public health meas
242 s confirm that Q8 is a CysLT1 antagonist and is sufficient to reduce cellular levels of NF-kappaB and
243 D2-MSNs within ventrolateral striatum (VLS) is sufficient to reduce goal-directed behaviours without
245 dated in vivo by evidence that LZK silencing was sufficient to reduce tumor growth in a xenograft mod
247 ver, it is not clear if Dam1 phosphorylation is sufficient to regulate the stability of kinetochore a
248 d sensory, motor, and cognitive stimulation, is sufficient to rescue binocular matching to the level
249 ession of beta2ARs only in airway epithelium is sufficient to rescue IL-13-induced AHR, inflammation,
250 how that mitochondrial targeting of catalase is sufficient to rescue redox transients, SOCE, and Orai
251 ipocyte-specific increase of Lsd1 expression is sufficient to rescue the age-related transition of be
252 l, that over-expression of VEGF-A165 b alone is sufficient to rescue the increase in proteinuria, as
253 ein and demonstrate EIN2 C terminus (EIN2-C) is sufficient to rescue the levels of H3K14/23Ac of ein2
254 (Ppara), and treatment with a Ppara agonist is sufficient to rescue the loss of beige adipocytes cau
255 aspiration to show that anisotropic tension is sufficient to rescue the resolution, but not the form
256 ith even a threshold-activating amount of Ag is sufficient to rescue their entry into the GC response
258 n selectively in brainstem serotonin neurons was sufficient to rescue loss of TPH2 immunoreactivity a
259 hermore, leptin treatment for 9 days or more was sufficient to restore AgRP innervation to both the P
265 bile acid sequestration with cholestyramine was sufficient to reverse the observed heart dysfunction
266 GSK2334470 or the CDK2 inhibitor dinaciclib was sufficient to reverse these events and to restore th
268 demonstrate that loss of one allele of PTEN is sufficient to shift isoform dependency from p110alpha
269 others' milk, starting at 0.5 mo postpartum, was sufficient to shift the hedonic tone, which resulted
270 population of 5-HT2CR neurons within the VTA is sufficient to significantly reduce homeostatic feedin
272 s, brief periods of anesthesia with propofol were sufficient to significantly increase bacterial burd
273 hat a single methylated H3K36 per nucleosome was sufficient to silence cryptic transcription in vivo.
274 ration of synthetic miRNA-lipid formulations is sufficient to stimulate cardiac repair and restoratio
277 cluster models suggest a single zinc ion may be sufficient to support phosphoethanolamine transfer.
279 we suggest that environmental selection may be sufficient to suppress and stymy sexual conflict if i
280 D-L1 on MC38 colorectal adenocarcinoma cells is sufficient to suppress antitumor immunity, as deletio
281 rgeting of the oncogenic MUC1 subunit MUC1-C is sufficient to suppress PD-L1 expression in TNBC cells
283 These findings indicate that OCT4 expression is sufficient to sustain intrinsic signaling in a LIF-in
284 adaptive, and for seven species, plasticity is sufficient to track geographic variation in the optim
285 mild pressure conditions (7.4 GPa at 300 K) are sufficient to transform ammonia monohydrate from a p
286 that the acquisition of a virulence plasmid is sufficient to transition beneficial symbionts to phyt
287 echanisms, Src family kinase (SFK) signaling is sufficient to transmit the CSF-1 lineage instructive
291 ECM detachment of cells lacking alpha6beta4 is sufficient to trigger ferroptosis because GPX4 is sup
292 Oligomerization of the long isoform of RTN3 is sufficient to trigger fragmentation of ER tubules.
293 nifedipine, a l-type Ca(2+) channel blocker, is sufficient to trigger RRP but not SRP exocytosis.
295 erin that, when imposed in ectodermal cells, is sufficient to trigger their internalization without a
296 gth protein, indicating that binding to MinD is sufficient to trigger this conformational transition
297 demonstrated that two operational principles are sufficient to understand how this remarkable result
299 r studies indicate that CD40 in Muller cells is sufficient to upregulate retinal inflammatory markers
300 n cue that directs people to forget one item is sufficient to wipe the corresponding trace from the h
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