ライフサイエンスコーパス: be thought to

1 Spatiotemporal variations of neurogenesis are thought to account for the evolution of brain shape.

2 New LINE-1 insertions are thought to accumulate mostly during human embryogene

3 tors of pentameric ligand-gated ion channels are thought to act on elements of the pathways that coup

4 vity versus other P2Y receptor subtypes, and is thought to act as an allosteric antagonist.

5 Although Tau interaction with membranes is thought to affect some of its physiological functions

6 d by abnormalities in prefrontal cortex that are thought to allow drug-associated cues to drive compu

7 genetically linked receptor-ligand pairs and are thought to allow for NK cell-mediated immunosurveill

8 current excitatory synaptic connections that are thought to amplify signals, form selective subnetwor

9 Late I-waves are thought to arise from trans-synaptic cortical inputs

10 This limit is thought to arise from the brain's capacity to flexibl

11 Hybrid dysfunction is thought to arise most commonly through negative inter

12 While these DEK-deficiency phenotypes were thought to arise from a moderate attenuation of non

13 The others (AGO1, AGO3 and AGO4) have been thought to assemble with microRNAs to form slicer-i

14 ccumulated within dystrophic neurites, which is thought to augment Abeta-induced synaptotoxicity by A

15 hanges in synaptic strength and connectivity are thought to be a major mechanism through which many g

16 Viral infections are thought to be a significant factor contributing to t

17 Although plant SnRKs are thought to be activated by upstream kinases, the ove

18 the sensorimotor system (e.g., spinal cord) are thought to be assembled sequentially [10-14], making

19 Visual hallucinations and illusions are thought to be caused by specific cognitive and highe

20 over half the neurons in the human brain and are thought to be critical for learning.

21 However, glacial iron inputs are thought to be dominated by icebergs.

22 Changes in land use are thought to be driving the rise in reported P knowles

23 These memories are thought to be encoded by alterations within specific

24 These signals are thought to be essential for proper biogenesis and fu

25 ells in the dentate gyrus of the hippocampus are thought to be essential to memory function by decorr

26 rotein splicing and their nested HEN domains are thought to be functionally independent because of th

27 tion units (gene bodies) in the human genome are thought to be heavily methylated.

28 Because fibroblasts are thought to be implicated in cGVHD-elicited fibrosis

29 Epigenetic mechanisms are thought to be important for balancing effector and m

30 ovirus (HCMV) envelope pentamer complex (PC) are thought to be important for preventing HCMV transmis

31 For example, gene-rich mitochondrial genomes are thought to be indicative of an ancient divergence, b

32 g., marine polychaetes and squids), minerals are thought to be indispensable for tooth-hardening and

33 locomotion and the change in cortical state are thought to be initiated by projections from the mese

34 netic driver genes have been identified that are thought to be involved in early stages of tumorigene

35 se independent collagen and laminin networks are thought to be linked by several additional extracell

36 duction.Protein-tyrosine phosphatases (PTPs) are thought to be major targets of receptor-activated re

37 tion, and validation of synaptic connections are thought to be mediated by interactions between pre-

38 st formation and function, and these effects are thought to be mediated by the transcription factor n

39 primates, posterior auditory cortical areas are thought to be part of a dorsal auditory pathway that

40 gomers of the amyloid-beta peptide (AbetaOs) are thought to be proximal neurotoxins involved in early

41 tic mutations in candidate driver (CD) genes are thought to be responsible for at least some cases of

42 d prevalence of neuroendocrine tumors (NETs) are thought to be rising, but updated epidemiologic data

43 Modern desert rodent communities are thought to be strongly structured by competitive int

44 opulations in present-day Pakistan and India are thought to be the descendants of such slaves, yet th

45 The beta1 and beta2 are thought to be the dominant myocyte ARs.

46 G(+)) bacteria, most commonly staphylococci, are thought to be the main pathogens.

47 Fibroblasts/myofibroblasts are thought to be the major cell type involved in encaps

48 stead, axon autonomous, intrinsic mechanisms are thought to be the primary driver for this type of ax

49 affolds, and hydrophobic membrane insertions are thought to be the primary drivers of fission.

50 Many of these changes are thought to be the result of increased reward-value c

51 As stem cells are thought to be the tumor precursor cells, visualizing

52 These patterns are thought to be ubiquitous across temperate forests, a

53 Pulsatile dynamics are thought to be widespread, and single-cell live imagi

54 For 20 years, this difference has been thought to be due to chemical impurities in the lab

55 s called active zone material (AZM) that has been thought to be involved in SV release.

56 ts activity was discovered in 1939, has long been thought to be monomorphic.

57 at, while all MutS-recognized mismatches had been thought to be repaired in a consistent manner, the

58 NRGs have generally been thought to be transported to axons and presynaptic

59 entations corresponding to recent experience is thought to be a critical mechanism supporting long-te

60 acked with the CO2-fixing enzyme Rubisco and is thought to be a crystalline or amorphous solid.

61 ortant for growth in intestinal mucus, which is thought to be a major source of nutrients for E. coli

62 ly to bile duct and lack of adequate HA flow is thought to be a risk factor for biliary complications

63 The formation and retrieval of a memory is thought to be accomplished by activation and reactiva

64 stent increase in synaptic transmission that is thought to be affected in Alzheimer's disease (AD).

65 Arsenite oxidase is thought to be an ancient enzyme, originating before t

66 resulting from deleterious gene combinations is thought to be an important step toward reproductive i

67 regulation in putaminal and pallidal regions is thought to be an underlying feature of this complicat

68 d inhibition of fear or behavioral responses is thought to be central to PTSD symptomatology, but its

69 ripples, and the cortical slow oscillations-is thought to be critical for memory consolidation durin

70 referred to as a transmission interface and is thought to be critical for the regulated channel acti

71 ecombination (HR)-mediated DNA repair, which is thought to be critical for tumor suppression.

72 The formation of functional spine synapses is thought to be critically dependent on presynaptic glu

73 ay induce at neighboring non-active synapses is thought to be detrimental for the specificity of memo

74 agment processing during DNA replication but is thought to be dispensable for DNA end resection.

75 STATEMENT: The neural representation of time is thought to be distributed across multiple functionall

76 Chronic pain is thought to be driven by changes in the excitability o

77 The underlying mechanism is thought to be due to chronic inflammation from indole

78 The principal source of this Fe is thought to be dust transported from southern mid-lati

79 Conformational freedom of the FMN domain is thought to be essential for the electron transfer (ET

80 regulation, and the ACC has motor areas and is thought to be important for error detection, the dial

81 itive selection, but the CD8(+)-lineage fate is thought to be induced by cytokines after TCR signalin

82 Decision confidence is thought to be intimately linked to the decision makin

83 NfnI is thought to be involved in maintaining the cellular re

84 s a key homeostatic plasticity mechanism and is thought to be involved in the regulation of cortical

85 isms are unknown, massive cytokine secretion is thought to be involved.

86 This side effect is thought to be mediated by free iodide in ICM formulat

87 ion in borderline personality disorder (BPD) is thought to be mediated through emotion dysregulation

88 lian cardiomyocyte regeneration after injury is thought to be minimal.

89 Although modified neuronal excitability is thought to be of significance, the contribution that

90 Autoimmunity is thought to be one of the most frequent causes of CSU.

91 The origin of these scars is thought to be perivascular cells entering lesions on

92 on.SIGNIFICANCE STATEMENT Visual information is thought to be processed in two distinctive pathways:

93 t V1.SIGNIFICANCE STATEMENT Our visual field is thought to be represented faithfully by the early vis

94 binding to endogenous proteins (haptenation) is thought to be required for activation of the immune s

95 Although increased intrinsic noise is thought to be responsible for a range of perceptual d

96 Fine particulate matter (PM2.5) is thought to be responsible for many of these health im

97 In addition, ToxR is thought to be responsive to various environmental cue

98 Sympatric speciation is thought to be strongly linked to resource specializat

99 t of as yet unknown structure, mycofactocin, is thought to be synthesized in this way via the mft gen

100 endent on intracellular Ca(2+) transport and is thought to be the cellular equivalent of learning and

101 An expansion of the cerebral neocortex is thought to be the foundation for the unique intellect

102 A key mechanism of this treatment is thought to be the generation of ketones, which provid

103 Their primary mechanism of action is thought to be the inhibition of phosphorylation of th

104 he ubiquitin-protein E3A ligase (UBE3A) gene is thought to be the predominant molecular cause of the

105 Antagonism of D2R signaling in the striatum is thought to be the primary mode of action of antipsych

106 Synaptic plasticity is thought to be the principal neuronal mechanism underl

107 bition of PI3K-dependent exocytosis of TRPC6 is thought to be the underlying mechanism, and recent st

108 Rev-erbbeta was thought to be a heme sensor based on a weak Kd value

109 Ulocladium was thought to be a strictly asexual genus of filamentou

110 form the conserved catalytic interface that was thought to be essential for ATP synthesis, and canno

111 Earlier, CHAOS was thought to be incompatible with life; however, with

112 ropherograms, because longitudinal diffusion was thought to be the only factor that contributes to ba

113 Actin was thought to be the sole cytoskeleton compartment pres

114 t that FISP may not have been the success it was thought to be.

115 cs) and apoptosis (cell life/death decision) were thought to be separate.

116 many years, the penicillin-binding proteins were thought to be the key enzymes required for wall syn

117 Females are thought to benefit from the nutrition contained in t

118 Alterations to the epigenome are thought to capture and mediate the effects of geneti

119 itory synaptic transmission, and this defect is thought to cause epileptic activity.

120 cis-regulatory elements of these regulators are thought to constitute the major driver of morphologi

121 While adult islets are thought to contain functionally mature beta cells, r

122 ine and terrestrial seeps and mud volcanoes) are thought to contribute around 52 teragrams of methane

123 d because COX- and 5-LOX-derived eicosanoids are thought to contribute to Abeta plaque deposition, th

124 In addition, we describe factors that are thought to contribute to escalation of commitment be

125 Defects in these events are thought to contribute to several human diseases.

126 c acid (KYNA) in the prefrontal cortex (PFC) are thought to contribute to the development of cognitiv

127 m infections are common in endemic areas and are thought to contribute to the maintenance of malaria

128 While epigenetic factors are thought to contribute to this process, the underlyin

129 lls after extracorporeal photopheresis (ECP) is thought to contribute to how ECP exerts its therapeut

130 Defective mitophagy is thought to contribute to normal aging and to various

131 rates the stress response, and excessive CRF is thought to contribute to the pathophysiology of these

132 ntifungals to hyphae within necrotic lesions is thought to contribute to therapeutic failure in invas

133 ns (PHBs) are highly conserved proteins that are thought to control the cell cycle, senescence and tu

134 nt derived from the anterior stripe of cells is thought to control growth and patterning of the Droso

135 The androgen receptor (AR) is thought to control the expression of morphogenetic ge

136 ns of the rostral ventromedial medulla (RVM) are thought to critically contribute to this process; ho

137 rane and cytosolic proteins in primary cilia is thought to depend on intraflagellar transport (IFT) a

138 Fine-grained coding of location is thought to depend on the hippocampus.

139 In Caenorhabditis elegans, the AWC neurons are thought to deploy a cGMP signaling cascade in the de

140 Furthermore, cells of the NP are thought to derive from the notochord, although adult

141 Finally, amphetamine, that is thought to disrupt DAT OF conformation, reduced the c

142 uadruplex region near the replication origin are thought to drive replication of mtDNA by generation

143 Although actomyosin forces have been thought to drive interface contraction, initiation

144 Ca(2+) binding to synaptotagmin-1, -2, or -9 is thought to drive fast synaptic transmission, whereas

145 e Pv or the dLGN, striate cortex projections are thought to either strongly "drive", or more subtly "

146 mbles into large 12-meric holoenzymes, which is thought to enable regulatory processes required for s

147 Dopamine neurons are thought to encode novelty in addition to reward pred

148 al disorder-a measure of urban deterioration-is thought to encourage crime and high-risk behaviors, l

149 Binocular mechanisms for visual processing are thought to enhance spatial acuity by combining match

150 e of plants to phosphate (Pi) deficiency and is thought to enhance a plant's ability to forage for th

151 independently, and many different mechanisms are thought to explain their effects on action and cogni

152 Lipid modification is thought to facilitate the interaction of the protein

153 This was thought to facilitate early ejection, but had not be

154 Dendritic cells (DCs) are thought to form a dendritic network across barrier s

155 They are thought to form higher-order protein complexes for t

156 ssemblies referred to as RNP granules, which are thought to form through multiple protein-protein int

157 Structured knowledge is thought to form, in part, through the extraction and

158 groups of 14-3-3s, one of which - epsilon - is thought to fulfill conserved cellular functions.

159 injection of a TRPV channel inhibitor, which are thought to function as an endocannabinoid receptor.

160 Conversely, deregulation of Dnmt3b is thought to generally promote tumorigenesis.

161 The brain is thought to generate internal predictions to optimize

162 ynaptic changes in auditory brain areas that are thought to give rise to auditory perception deficits

163 cell (CSC) subpopulations within tumors that are thought to give rise to recurrent cancer after thera

164 Different olfactory cortical regions are thought to harbor distinct sensory representations,

165 producers of indole-sulfur phytoalexins that are thought to have an important role in plant disease r

166 glacial period (115,000 to 11,650 years ago) are thought to have been driven by imbalances in the rat

167 Several phototrophic bacterial clades are thought to have evolved before oxygenic photosynthes

168 Large tertiary care hospitals (TCHs) are thought to have higher antimicrobial resistance (AMR

169 Mitochondria are thought to have originated as free-living prokaryote

170 Leprosy has long been thought to have a strong genetic component, and so

171 Neurite outgrowth inhibitor A (Nogo-A) is thought to have a role in the pathophysiology of amyo

172 Release of serotonin (5-HT) is thought to have an important role in the increase in

173 Although NO produced by iNOS is thought to have direct bactericidal activity against

174 This is thought to have evolutionary origins, highlighting ob

175 rodites) as found in Caenorhabditis elegans, is thought to have evolved from dioecy (males/females) t

176 This shift is thought to have important implications for stress-rel

177 The early diversification of Solanaceae is thought to have occurred in South America during its

178 own asteroids and comets in the Solar System is thought to have originated outside it, despite models

179 g other aspects of individual behaviour that are thought to impact the rate of population spread.

180 Senescent cells are thought to impair tissue function, and their genetic

181 This process is thought to impair osteogenic and hematopoietic regene

182 fferentiation of regulatory T cells (Tregs), was thought to imprint a unique and irreversible genetic

183 GNIFICANCE STATEMENT Seeing through two eyes is thought to improve visual acuity by enhancing sensiti

184 rill or small fish, and their large flippers are thought to increase their maneuverability and thus t

185 nal warming losses, where raised temperature is thought to increase maintenance energy demands and th

186 Malaria parasites are thought to influence mosquito attraction to human ho

187 Microbial products are thought to influence the progression of cholangiopat

188 beta-Amyloid (Abeta) aggregation is thought to initiate a cascade of neurodegenerative ev

189 n at immunoglobulin sites, their persistence is thought to interfere with DNA replication by slowing

190 Type 2 diabetes is thought to involve a compromised beta cell differenti

191 Coupling is thought to involve direct interactions between RNA po

192 Declarative memory recall is thought to involve the reinstatement of neural activi

193 Detailed memory retrieval is thought to involve the reinstatement of those represe

194 asodilatation and fluid extravasation, which are thought to lead to the life-threatening anaphylactic

195 The macronutrient phosphorus is thought to limit primary productivity in the oceans o

196 up of slowly dividing quiescent center cells is thought to limit stem cell activity to directly neigh

197 ch as those against oxidized lipid epitopes, are thought to mainly derive from T cell-independent inn

198 Circulating IL-6 is thought to maintain energy status during exercise by

199 ing the filling of holes in the valence band are thought to make important contributions to the low-e

200 onally, human primary visual cortex (V1) has been thought to mature within the first few years of lif

201 Cortico-basal ganglia circuits are thought to mediate goal-directed learning by a proce

202 gp120, including the tripeptide motif LDV/I, are thought to mediate gp120-alpha4beta7 binding.

203 ted widely among Gram-negative pathogens and are thought to mediate interstrain competition.

204 Classically, the CD56dim NK cell subset is thought to mediate antitumor responses, whereas the C

205 otein, cysteine- and glycine-rich protein 3, is thought to mediate cardiac mechanotransduction and st

206 This GABAA receptor subtype is thought to mediate sedation.

207 Hydration water on the surface of a protein is thought to mediate the thermodynamics of protein-liga

208 nsmembrane cargos to endosomes and lysosomes is thought to occur at the TGN through recognition of so

209 virus capsids are icosahedral, and assembly is thought to occur by the sequential addition of capsid

210 n depth in goldfish and zebrafish [1, 2] and is thought to occur in other species [3, 4].

211 elayed small bowel perforation following BAT is thought to occur secondary to mesenteric hematoma for

212 Histone H3 lysine 36 methylation (H3K36me) is thought to participate in a host of co-transcriptiona

213 ironment and their spatiotemporal variations are thought to play a central role in sculpting embryoni

214 neration in the multiple sclerosis brain and are thought to play a central role in the disease proces

215 in early steps of cortical circuit assembly are thought to play a critical role in vulnerability to

216 pendent changes in brain inhibitory circuits are thought to play a key role during the "critical peri

217 Ionotropic glutamate receptors are thought to play an essential role during development

218 Antibodies are thought to play an essential role in naturally acqui

219 (miRNAs) are often deregulated in cancer and are thought to play an important role in cancer developm

220 rans interactions between dynamin rungs that are thought to play critical roles in membrane constrict

221 allel pathways of olfactory bulb output that are thought to play distinct functional roles in odor co

222 eptors (D2Rs) in the prefrontal cortex (PFC) are thought to play important roles in behaviors, includ

223 tions with metal ions and phenolic compounds are thought to play important roles.

224 igation and episodic memory, the hippocampus is thought to play a critical role in disambiguating (pa

225 Dopamine is thought to play a critical role in reinforcement lear

226 letely understood, mitochondrial dysfunction is thought to play a crucial role in disease pathogenesi

227 ing local nucleosome-nucleosome interactions is thought to play a crucial role in regulating transcri

228 Although this event is thought to play a key role in priming RAF activation,

229 ellular spatial alteration in RNA metabolism is thought to play a key role.

230 ) in cirrhosis is multifactorial and ammonia is thought to play a key role.

231 transforming growth factor beta (TGF-beta), is thought to play a pivotal role.

232 Amyloid-beta (Abeta) is thought to play an essential pathogenic role in Alzhe

233 protein-coupled estrogen receptor 1 (GPER1), is thought to play important roles in breast cancer and

234 posi's sarcoma-associated herpesvirus (KSHV) is thought to play key roles in disease, including KSHV-

235 which act by reducing bone remodelling, and are thought to prevent perforations and maintain microst

236 ong development times of tropical birds have been thought to primarily reflect evolved physiological

237 Fe-mediated biological nitrogen fixation is thought to proceed via either a sequence of proton an

238 induced by Ca(2+) binding to synaptotagmin-7 is thought to produce delayed synaptic signaling, enabli

239 THC is thought to produce the main psychoactive effects of c

240 In general, Ras proteins are thought to promote cardiac hypertrophy, an important

241 nking by myosins and nonmotor cross-linkers, are thought to promote contractility.

242 wide range of histone methyltransferases and are thought to promote tumorigenesis.

243 vation of complement in the kidney have long been thought to promote inflammation and lupus nephritis

244 tion of numerous proteins, and this increase is thought to promote cell survival.

245 retained from whole genome duplication (WGD) is thought to promote evolutionary diversification.

246 SIGNIFICANCE STATEMENT: Reward motivation is thought to promote memory by supporting memory consol

247 pocampal neural representations during sleep is thought to promote systems consolidation of declarati

248 ing in the horizontal plane, and these cells are thought to provide animals with an internal compass.

249 ats (mangroves and tidal marshes) seagrasses are thought to provide coastal defence and encourage sed

250 Starvation induces liver autophagy, which is thought to provide nutrients for use by other organs

251 The LHb is thought to provide reward-related contextual informat

252 These intermediate movements are thought to reflect an unintentional averaging of the

253 GNIFICANCE STATEMENT Alpha-band oscillations are thought to reflect cortical excitability and are the

254 typed electrophysiological oscillations that are thought to reflect profound disruptions of activity

255 random subset from source communities, which is thought to reflect dispersal limitation.

256 Adaptation of prions to new species is thought to reflect the capacity of the host-encoded c

257 This pattern is thought to reflect trends in temperature variability:

258 Resident immune cells are thought to regulate adipocyte activity.

259 rons are heterogeneous, and distinct subsets are thought to regulate different behaviors.

260 es are membrane-less droplet organelles that are thought to regulate posttranscriptional gene express

261 These tripartite complexes are thought to regulate synapses.

262 , species that adopt a sit-and-wait strategy are thought to rely on visual cues primarily, while acti

263 cally connected cell assemblies or "engrams" are thought to represent memories of past experience.

264 All other division proteins are thought to require the Z-ring for recruitment to the

265 Hebbian plasticity is thought to require glutamate signalling.

266 Successful antitumor immunity is thought to require T cell entry into tumors, though m

267 that are resistant to conventional therapies are thought to reside in protective niches.

268 ts and up to four KCNE1 beta-subunits, which are thought to reside within external clefts of the chan

269 s and orientation map organization, mouse V1 is thought to respond to local orientation and visual mo

270 While eating disorders (EDs) are thought to result from a combination of environmenta

271 and their propagation along neural circuits are thought to result in neurodegeneration causing Alzhe

272 Cystic fibrosis (CF)-related diabetes (CFRD) is thought to result from beta-cell injury due in part t

273 encephalopathy is characterized by coma and is thought to result from mechanical microvessel obstruc

274 UPD is thought to result mostly from pre- or post-zygotic ch

275 the gas emission from these Arctic sediments was thought to result from gas hydrate dissociation, pos

276 Rods, active under dim illumination, are thought to saturate at higher (photopic) irradiances

277 s associated with a focus of Cdc42*GTP which is thought to self sustain by recruiting a complex conta

278 The organelles are thought to sequester a private cofactor pool, minimi

279 assemble into filamentous structures, which are thought to serve additional regulatory functions.

280 plastic counterparts, mammary TICs (MaTICs), are thought to serve as the TICs for the claudin-low sub

281 Magnetic honeycomb iridates are thought to show strongly spin-anisotropic exchange i

282 Although BM formation is thought to simply involve a process of self-assembly

283 l MoMLV pathogenesis.IMPORTANCE Retroviruses are thought to spread primarily via direct cell-to-cell

284 cluding Alzheimer's and Parkinson's disease, are thought to spread to increasingly larger areas of th

285 rough the breakdown of silicate minerals and is thought to stabilize Earth's long-term climate.

286 alized extracellular matrix (ECM) remodeling is thought to stabilize the cleavage furrow and maintain

287 sms to disperse throughout their environment is thought to strongly influence population structure an

288 Conversion of PrP(C) into PrP(Sc) is thought to take place at the cell surface or in endol

289 DTPs were thought to target RNA polymerase, but conflicting o

290 migration and scattering by mechanisms that are thought to tip a local balance of competing physical

291 Autosomal dominant mutations in STING are thought to trigger activation of IRF3 and subsequent

292 Histamine intolerance is thought to trigger manifold clinical symptoms after i

293 t mechanism by which the virus-infected cell was thought to undergo programmed cell death.

294 nges induced by long-term potentiation (LTP) are thought to underlie memory formation.

295 ), medial frontal cortex (MFC), and amygdala are thought to underlie several psychiatric conditions,

296 athic alpha-synuclein (alpha-syn) aggregates is thought to underlie the progression of neurodegenerat

297 AAA+ unfoldases are thought to unfold substrate through the central pore

298 Replicative hexameric helicases are thought to unwind duplex DNA by steric exclusion (SE

299 Cytotoxic T cells infiltrating tumors are thought to utilize HIF transcription factors during

300 oli, the lipid II transporter candidate FtsW is thought to work in concert with the PG synthases peni