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1 tion (GSIS), the effect of obestatin on GSIS is unclear.
2 emerging drug target, but its oncogenic role is unclear.
3 ino acid substitution, on the motor function is unclear.
4 membrane "reservoir" for the additional area is unclear.
5 mechanism on how auxin carries out this work is unclear.
6 pecially in organ-specific adult stem cells, is unclear.
7 ctors to RSV mortality in low-income regions is unclear.
8 an society, but whether it exists in rodents is unclear.
9 arability of results among different methods is unclear.
10 1, but the reason for this phenotypic change is unclear.
11 and reorganizes chromatin during DNA repair is unclear.
12 intense sensation associated with allodynia is unclear.
13 activity, although the underlying mechanism is unclear.
14 lations, but its effect on surgical outcomes is unclear.
15 scopy and the value of surveillance for them is unclear.
16 heir response to contemporary climate change is unclear.
17 ramming relates to embryonic differentiation is unclear.
18 faculty are changing their teaching methods is unclear.
19 of mature domains in targeting and secretion is unclear.
20 RK2's normal physiological role in the brain is unclear.
21 illin-resistant Staphylococcus aureus (MRSA) is unclear.
22 between African American and white subjects is unclear.
23 How cells decide which way to die is unclear.
24 es, but the role of individual-level factors is unclear.
25 al role of the TJ in the glomerular podocyte is unclear.
26 ts MRN activation at dysfunctional telomeres is unclear.
27 e effect of cannabis on medication adherence is unclear.
28 s) by which mutant HTT (mHTT) causes disease is unclear.
29 rst to interact with the cardiac parenchyma, is unclear.
30 pathology, although the underlying mechanism is unclear.
31 ing meiotic chromosome separation in oocytes is unclear.
32 ally translates into behavioural variability is unclear.
33 the pathophysiological role of T lymphocytes is unclear.
34 usions affects these long-range interactions is unclear.
35 e inflammatory response, but how this occurs is unclear.
36 okalaemia, however, the underlying mechanism is unclear.
37 reconstructive surgery among these patients is unclear.
38 appearing in a tissue, but what drives this is unclear.
39 etastatic microenvironment in distant organs is unclear.
40 upting chemicals (EDCs) on the immune system is unclear.
41 iquitous nature, the functional significance is unclear.
42 However, precisely how tau becomes toxic is unclear.
43 cers but how they promote cancer progression is unclear.
44 s, but how glia support neuronal cell bodies is unclear.
45 ferentiation, its role in dermal fibroblasts is unclear.
46 tivation of ethanol (EtOH)-induced steatosis is unclear.
47 nthesis and is highly homologous to CYP11B2, is unclear.
48 sing local, online and stable learning rules is unclear.
49 ich one is the major topoisomerase for mRNAs is unclear.
50 facilitating or protecting against apoptosis is unclear.
51 zation and fusion are then locally triggered is unclear.
52 activity, but the reason for this deficiency is unclear.
53 break repair and transcription processivity is unclear.
54 hieved during the development of vertebrates is unclear.
55 closely related to GRP, but its role in itch is unclear.
56 duction of downstream inflammatory cytokines is unclear.
57 ular diffusion of specific second messengers is unclear.
58 how ORC coordinates symmetrical MCM loading is unclear.
59 thality, although how lethality is triggered is unclear.
60 whether stimulus specific populations exist is unclear.
61 nts with different BRAF genetic backgrounds, is unclear.
62 hich its inactivation promotes tumorigenesis is unclear.
63 on and activity is regulated after secretion is unclear.
64 However, the mechanism is unclear.
65 ower and algal biomass substantially higher, is unclear.
66 asure similar constructs of clinical benefit is unclear.
67 ent inhibition of Pdc binding to Gtbetagamma is unclear.
68 ating renal processes linked to hypertension is unclear.
69 ain disease, but its role in the spinal cord is unclear.
70 enesis of systemic lupus erythematosus (SLE) is unclear.
71 hough the benefit of this treatment strategy is unclear.
72 nflammation and the subsequent tissue damage is unclear.
73 neity among cells, but how these are related is unclear.
74 , the mechanistic basis for this persistence is unclear.
75 its overall association with patient outcome is unclear.
76 Q tracts in many normal cytoplasmic proteins is unclear.
77 on loss in age-related macular degeneration, is unclear.
78 N-lambda acts to exert its antiviral effects is unclear.
79 ich Spata2 regulates the activation of RIPK1 is unclear.
80 nsive systolic blood pressure (SBP) lowering is unclear.
81 itant burden of health risk behaviors (HRBs) is unclear.
82 but how HSCs regain quiescence after stress is unclear.
83 branching form diversification in bryophytes is unclear.
84 D-1 in regulating pain and neuronal function is unclear.
85 icopathologic significance in thyroid cancer is unclear.
86 itically ill adults at high nutritional risk is unclear.
87 tive interactions revealed in the Y2H screen is unclear.
88 function, the role of which in lung immunity is unclear.
89 However, how it does so is unclear.
90 ic multimorbidity and allergic sensitization is unclear.
91 e cells code together a complex visual scene is unclear.
92 sequent risk of clinical episodes of malaria is unclear.
93 the regulation of early B cell lymphopoiesis is unclear.
94 gate formation, but the underlying mechanism is unclear.
95 y some gene mutations turn cells into losers is unclear.
96 hy, but how this arises at a molecular level is unclear.
97 DcpS inhibition leads to therapeutic benefit is unclear.
98 s, but the predictive power of this approach is unclear.
99 f trafficking for the more potent toxin STx2 is unclear.
100 ure and purpose of this preparatory activity is unclear.
101 ged 18 years and older with critical illness is unclear.
102 However, how ADS are recognized in cells is unclear.
103 ndscape of PT and TPS genes in plant genomes is unclear.
104 barrier to monitoring in different settings is unclear.
105 ery, although the nature of this association is unclear.
106 tional and evolutionary relationship to Ctr1 is unclear.
107 ons on Southern Hemisphere sub-polar islands is unclear.
108 ld-type allele contributes to leukemogenesis is unclear.
109 tablishes long-range signaling to leukocytes is unclear.
110 physiological and oncogenic functions of MYC is unclear.
111 oordinate/modulate several cellular pathways is unclear.
112 ars, but the potential magnitude of the loss is unclear.
113 irection of this association in older adults is unclear.
114 se prognosis than 1p/19q co-deleted tumours, is unclear.
115 associated with prior learning or experience is unclear.
116 balance inputs to attain specific responses is unclear.
117 matitis, but the signaling pathways involved are unclear.
118 on and functions during bacterial infections are unclear.
119 adult fibrosis, but the mechanisms of action are unclear.
120 DNMT1 and KIT orchestrate lung tumorigenesis are unclear.
121 nd neurocircuitry by which NPY decreases SNA are unclear.
122 ia, yet the rules that govern this selection are unclear.
123 However, how and where WNT1 acts in bone are unclear.
124 he underlying reasons for this mortality gap are unclear.
125 f immunosuppressive treatments with outcomes are unclear.
126 uditory attention, its neurobiological bases are unclear.
127 d mechanism(s) of low-pH inactivation of HSV are unclear.
128 t the mechanisms through which they interact are unclear.
129 the mechanisms that underlie this difference are unclear.
130 o the frequency and duration of surveillance are unclear.
131 ade modulates tumor evolution during therapy are unclear.
132 onal functions such as synaptic transmission are unclear.
133 y and metabolic dysfunction for reasons that are unclear.
134 s and atrophy, but the underlying mechanisms are unclear.
135 fter hypoxia or HIF-2alpha activation in CRC are unclear.
136 molecular mechanisms behind this gender bias are unclear.
137 t the underlying mechanisms of immune memory are unclear.
138 lying squamous cell carcinoma susceptibility are unclear.
139 ct hypoxia-mediated survival in GBM habitats are unclear.
140 cularly vulnerable to inflammatory processes are unclear.
141 nt-negative activity) in lung adenocarcinoma are unclear.
142 Thus, the functions of this modification are unclear.
143 iversity of B cell clones recruited into GCs are unclear.
144 s well, but their motivational underpinnings are unclear.
145 uts and the roles of particular ion channels are unclear.
146 mechanistic features underlying its function are unclear.
147 cular mechanisms and functional consequences are unclear.
148 ing effects of health system characteristics are unclear.
149 anisms by which ORMDL3 predisposes to asthma are unclear.
150 ancer, although its effects on tumorigenesis are unclear.
151 and the risk associated with these patterns are unclear.
152 ogical function and impact on miRNA networks are unclear.
153 pression, and cross-talk between CBS and CSE are unclear.
154 on is reversible and the possible mechanisms are unclear.
155 lthough its efficacy and mechanism of action are unclear.
156 viruses, but the mechanisms and consequences are unclear.
157 wering and its association with risk of ESRD are unclear.
158 nellar mechanisms underlying this capability are unclear.
159 (TSS), but its frequency of use and efficacy are unclear.
160 n of XB behavior in failing human myocardium are unclear.
161 Mechanisms underlying reservoir stability are unclear.
162 c pathways such as fatty acid beta-oxidation are unclear.
163 However, the precise mechanisms involved are unclear.
164 r functions in squamous cell carcinoma (SCC) are unclear.
165 e molecular details of this interaction have been unclear.
166 t its anatomical and compositional basis has been unclear.
167 pattern is transduced to daughter cells have been unclear.
168 role of lineage commitment factor Bcl11b has been unclear.
169 the reason that the fluids are oxidizing has been unclear.
172 associated impacts on fisheries productivity are unclear and could weaken the food security of hundre
173 ease-specific blood-brain barrier disruption is unclear, and this is an important future area of futu
174 y of minus-end-directed movement along actin is unclear as the underlying architecture of the local a
175 evelops in response to severe sepsis, but it is unclear as to how the proteolytic pathways that are i
176 ms of MV formation in Gram-positive bacteria are unclear, as these cells possess a single cytoplasmic
177 ype 35C from the closely related serotype 42 was unclear, as their reported cps loci are nearly ident
178 ciolosis is common in UK beef cattle, but it is unclear at what levels liver fluke burdens cause prod
179 ) Ca(2+)-permeable ion channels in platelets is unclear, despite the importance of shear stress in pl
182 for consolidating episodic memories, but it is unclear how CA1 activity patterns drive memory format
183 ss signals can induce either process, and it is unclear how cells 'assess' cellular damage and make a
184 repressive complexes modify histones but it is unclear how changes in chromatin states alter kinetic
187 require niches to maintain stemness, yet it is unclear how CSCs maintain stemness in the suboptimal
189 Batrachochytrium dendrobatidis (Bd), but it is unclear how dominant these anti-Bd bacteria are in sk
191 rate complex organ-like tissues; however, it is unclear how heterotypic interactions affect lineage i
192 dictate CNS function are multifaceted and it is unclear how irradiation induces persistent alteration
194 changes in SCN neuronal excitability, but it is unclear how mutations affecting post-translational mo
197 important for centrosome separation, but it is unclear how nuclear dynein forces are organized in an
198 temic lupus erythematosus (SLE); however, it is unclear how Ox40L contributes to SLE pathogenesis.
202 kinase C (PKC) phosphorylation, although it is unclear how store depletion stimulates this gating pa
204 ng for resources and instilling fear, but it is unclear how suppression of mesopredators varies with
206 aspects of this process are well studied, it is unclear how the cell controls the coordination of cel
207 the molecular control of cell movements, it is unclear how the different observed modes of collectiv
210 ent on the cellular NXF1/TAP pathway, but it is unclear how they are recruited to the export machiner
214 to aggregate local neuronal activity, but it is unclear how this relationship affects information enc
217 as the etiologic significance of results may be unclear (ie, the pneumonia may be caused by none, one
219 arction (AMI) without heart failure (HF), it is unclear if beta-blockers are associated with reduced
221 nomena are well described in vertebrates, it is unclear if invertebrates have distinct sleep stages.
222 d together by modular idempotent cloning, it is unclear if such simplified strategies scale to very l
225 bility in support to dental institutions, it is unclear if this net decline reflects a long-term tren
229 n lesion could cause such a complex disorder is unclear, leading many to speculate that concurrent de
231 or new infections, whereas an additional 34% were unclear since cultures were negative in one of the
232 small-diameter primary afferent neurons, it is unclear to what extent different NaV channel isoforms
235 ssumptions about fibril constitution, and it is unclear to-date what the molecular causes of this pol
237 iparatide and denosumab on BMD and fractures are unclear (very low SOE), and these medications may in
238 g pregnancy with child body composition have been unclear.We explored whether SCB intake during pregn
239 with artificially sweetened beverages (ASBs) is unclear.We aimed to evaluate the associations of ASB
240 homeostasis in response to glucose ingestion is unclear.We sought to determine the metabolic effects
241 te the conservation of this strategy, it has been unclear what selective pressure maintains the fitne
242 in trials, its definition is nonspecific; it is unclear what proportion represents arrhythmic deaths.
243 are increased in allergic asthmatics, but it is unclear what role airway basophils play in "TH2-low"
246 ters are variable within individuals, but it is unclear whether 1 semen sample could represent a man'
247 pe in the DENV3 envelope (E) protein, but it is unclear whether all interactions are needed for neutr
248 cell type involved in encapsulation, but it is unclear whether and how stem cells contribute to this
249 in PSAC/NPP establishment are unknown and it is unclear whether any of the RhopH proteins play a role
251 despite the castrate level of androgens, it is unclear whether AR signaling is significantly reprogr
252 N. cucumeris and T. putrescentiae exists, it is unclear whether both species share bacterial communit
255 lation/deamination and myeloperoxidation, it is unclear whether endogenous formaldehyde can initiate
258 of astrocyte morphology are unknown, and it is unclear whether impairing astrocytic infiltration of
259 ogenesis of congenital heart defects, but it is unclear whether individual common variants confer a l
262 lated overall sound intensity; therefore, it is unclear whether looming bias is truly a perceptual bi
266 common part of the physical examination, it is unclear whether performing screening pelvic examinati
268 a severe course of bipolar disorder, but it is unclear whether rapid cycling bipolar disorder is lin
271 ials have found the procedure to be safe, it is unclear whether safe adaptation of this approach from
273 atric surgical population are scarce, and it is unclear whether such preclinical findings are relevan
275 SD7A-Ab-positive patients is unknown, and it is unclear whether the clinical presentation differs bet
276 h allergic disease in young children, but it is unclear whether the effects persist to adolescence.
280 increase after hysterosalpingography, but it is unclear whether the type of contrast medium used (oil
281 als are present in many groups [1-8], but it is unclear whether their emergence is determined by thei
282 tric disorders such as schizophrenia, but it is unclear whether these abnormalities represent a cause
284 rtion of food products bear no label, and it is unclear whether these products are free from allergen
287 and EUE tend to correlate positively, but it is unclear whether they reflect different aspects of the
288 IFN-gamma, similar to Th1 cells; however, it is unclear whether they resemble Th1 or Th17 cells in te
290 ded for high-HIV-prevalence settings, but it is unclear whether this approach is sufficient to achiev
291 two structures significantly differ, and it is unclear whether this difference is due to an altered
293 A) has declined over the past decade, but it is unclear whether this represents a decline in S. aureu
298 and their origin and evolutionary trajectory are unclear, which greatly hinders functional studies.
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