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1 ransformation and leukemogenesis continue to be under investigation.
2 ed and how PPARgamma2 stimulates lipogenesis is under investigation.
3  known and its signal transduction mechanism is under investigation.
4 on, and in patients with newly diagnosed APL is under investigation.
5 f other markers of ventricular dys-synchrony is under investigation.
6 nimal genomes to support cellular complexity is under investigation.
7 ttern of EBV Ag expression (type II latency) is under investigation.
8 nctional region forms coiled coil structures is under investigation.
9 e of the cleavage to the function of TRP-ML1 is under investigation.
10 sing results and translation into the clinic is under investigation.
11 n of lysine residues within histone proteins is under investigation.
12  other treatments in this patient population is under investigation.
13       The mechanism of NSP3-mediated tropism is under investigation.
14 in promoting sickle cell dehydration in vivo is under investigation.
15 f all 64 codons for the species whose genome is under investigation.
16 erapy protects joints from structural damage is under investigation.
17  and its role in early stages of the disease is under investigation.
18 tion potential of these c-kit-positive cells is under investigation.
19 in ionizing radiation resistance/sensitivity is under investigation.
20 The use of DLI to treat certain solid tumors is under investigation.
21 sm, especially the role of its PLP cofactor, is under investigation.
22 sociated with lithium's therapeutic efficacy is under investigation.
23 or cellular and viral RNAs exists in mammals is under investigation.
24 B recurrence following liver transplantation is under investigation.
25 decrease in the in vivo trimethylamine level is under investigation.
26         The fine structure of the B6 epitope is under investigation.
27 se of allogeneic bone marrow transplantation is under investigation.
28 hecins to redistribute their own drug target is under investigation.
29 y has been introduced and its clinical niche is under investigation.
30                       The molecular etiology is under investigation.
31 tion between CD33 expression and GO response is under investigation.
32  effect using third-party regulatory T cells is under investigation.
33 pathogenetic contribution of these mutations is under investigation.
34 , uterine-limited, high-grade leiomyosarcoma is under investigation.
35 servation with the proteins studied in flies is under investigation.
36                 The mechanism of this effect is under investigation.
37  by hydrolysis of the putative metabolite 16 is under investigation.
38 block in a small subset of 'at-risk' fetuses is under investigation.
39      Its role in pathogenesis or progression is under investigation.
40 umber of different therapies to inhibit AGEs are under investigation.
41  role and that of angiogenic blockade in CRT are under investigation.
42 phage migration inhibitory factor production are under investigation.
43                 The therapeutic implications are under investigation.
44                  New treatment interventions are under investigation.
45 tterning, genes encoding signaling molecules are under investigation.
46 romising new drugs targeting other receptors are under investigation.
47 rlying mechanism of this type of endocytosis are under investigation.
48                   Other antidiarrheal agents are under investigation.
49 ly described but poorly understood syndromes are under investigation.
50 lization as well as polymeric materials that are under investigation.
51 lexes and their role in MAP kinase signaling are under investigation.
52 e-specific proteins have been identified and are under investigation.
53 nd the mechanisms underlying their induction are under investigation.
54  mechanisms that up-regulate HDM2 expression are under investigation.
55 h has proven to be reliable, but new methods are under investigation.
56 human PAP, defects in GM-CSF function in PAP are under investigation.
57 geted to molecular lesions of leukemic cells are under investigation.
58  its relationship to hK2 and prostate cancer are under investigation.
59 yte growth and development factor (PEG-MGDF) are under investigation.
60 nt of humanized and bifunctional antibodies, are under investigation.
61 ng storage, alternative preservation methods are under investigation.
62 otherapy and the novel monoclonal antibodies are under investigation.
63 ath 1 and cytotoxic T-lymphocyte antigen 4), are under investigation.
64                   Other candidate prebiotics are under investigation.
65 e therapeutics relevant to the IFN-I pathway are under investigation.
66 n 50 years, many other immunological targets are under investigation.
67 tives such as galacto-oligosaccharides (GOS) are under investigation.
68 ontrol, and several immunotherapy strategies are under investigation.
69 ing the mechanism of inflammation (IL-1beta) are under investigation.
70 py agents, including Prostvac and ipilimumab are under investigation.
71  spectrum of dysfunctions associated with MS are under investigation.
72 umors with PET, and its isolated enantiomers are under investigation.
73            A variety of promising new agents are under investigation.
74 ccine strategies to capture these activities are under investigation.
75 ative imaging and cell analysis technologies are under investigation.
76 xtended dose schedules of ezatiostat tablets are under investigation.
77 mitted resistant virus on treatment outcomes are under investigation.
78 the cooperative movements involved in gating are under investigation.
79 agents and somatostatin-tagged radionuclides are under investigation.
80 iminary tests, many methods for improvements are under investigation.
81 nction, and CD8 differentiation and function are under investigation.
82 d at cytoprotection or reduction of fibrosis are under investigation.
83 ional approach to impedance microbiology has been under investigation.
84              Additional radiopharmaceuticals are under investigation and appear promising.
85 astrointestinal tract have been developed or are under investigation and could increase safety.
86  to address poor cell retention and survival are under investigation and include the following: coadm
87 ns that favor expression of the cydAB operon are under investigation and may be linked to the acid se
88  vascular endothelial growth factor receptor are under investigation and show promise as well.
89 combinant and purified coagulation therapies are under investigation, and provide clinicians specific
90               Bone marrow-derived stem cells are under investigation as a treatment for ischemic hear
91 f human bronchial epithelial (HBE) cells and are under investigation as agents for lung cancer preven
92 activating molecule 7, and kappa light chain are under investigation as CAR targets.
93 hanolamine (DSPE) as the targeting component are under investigation as mediators of drug and gene de
94  in poor prognosis of human solid tumors and are under investigation as molecular targets for cancer
95 n infection, and inhibitors of these systems are under investigation as next-generation antibiotics.
96    Small-molecule Tau aggregation inhibitors are under investigation as potential therapeutic agents
97                 A variety of biologic agents are under investigation as potential treatments for SLE.
98                           AK inhibitors have been under investigation as antinociceptive, antiinflamm
99 rCer is a water-soluble ceramide analog that is under investigation as a cancer drug.
100 bition of tumor-associated FAS hyperactivity is under investigation as a chemotherapeutic target.
101 Autologous skeletal myoblast transplantation is under investigation as a means to repair infarcted my
102 (LPS), is employed as a vaccine adjuvant and is under investigation as a non-specific immunomodulator
103 yrophosphoryldolichol (GlcNAc-P-P-dolichol), is under investigation as a possible site of metabolic r
104            The sodium/iodide symporter (NIS) is under investigation as a reporter for noninvasive ima
105 to Leu at position 34 in the FXIII A subunit is under investigation as a risk determinant of thrombos
106                                       HLA-DR is under investigation as a target for monoclonal antibo
107 vascular disease, because recombinant apoA-I is under investigation as a therapeutic agent and mutant
108  The epidermal growth factor receptor (EGFR) is under investigation as a therapeutic target for cance
109 ely used to monitor responses to therapy and is under investigation as a therapeutic target.
110                         Normobaric hyperoxia is under investigation as a treatment for acute ischaemi
111 saccharide (LPS) from Neisseria meningitidis is under investigation as a vaccine for prevention of me
112                                  Cabergoline is under investigation as an abortifacient in canid spec
113  functional anti-Env and anti-Tat activities are under investigation, as is a possible synergy betwee
114 ems are chosen for review here, all of which are under investigation at the Molecular Foundry, to ill
115                           Oral immunotherapy is under investigation but may be limited in future use
116            A number of prevention strategies are under investigation, but early introduction of peanu
117 promising new medical and surgical therapies are under investigation, but further research is require
118 of TRPV1 activation by selective antagonists is under investigation by several pharmaceutical compani
119 nal denervation and carotid barostimulation, are under investigation especially in patients with adva
120 ne or more concentric graphene cylinders and are under investigation for a variety of applications th
121 ents, and several novel treatment approaches are under investigation for high-risk or relapsed patien
122 ition to virologic effects, CCR5 antagonists are under investigation for immune-modulating effects an
123          Several perfusion balloon catheters are under investigation for local drug delivery; however
124 f action, such as cardiac myosin activators, are under investigation for patients with heart failure
125  plethora of endoscopic tools and procedures are under investigation for primary and revisional obesi
126 for treatment of pulmonary hypertension, and are under investigation for treatment of heart failure.
127  factor infected cell protein 34.5 (ICP34.5) are under investigation for use in the therapeutic treat
128 e molecular mechanisms of schizophrenia have been under investigation for decades; however, the exact
129       PDEF (prostate-derived Ets factor) has been under investigation for its role in tumor developme
130 eraction and ET between the two proteins has been under investigation for over 30 years, the second r
131                       Although this area has been under investigation for over a decade, the scope an
132 sed in the laboratory of Fujii-Kuriyama have been under investigation for several years because of th
133       Allogeneic bone marrow transplantation is under investigation for a range of nonmalignant indic
134 cellent in vivo activity in HAND models, and is under investigation for further development.
135                                 Radiotherapy is under investigation for its ability to enhance respon
136                                   Evolocumab is under investigation for its effects on cardiovascular
137 e (ERSR) and associated protein aggregation, is under investigation for its role in human diseases, i
138 '-fluorothymidine (FLT), a thymidine analog, is under investigation for monitoring cellular prolifera
139 re given shorter regimens, and weekly dosing is under investigation for preventive therapy and for th
140 tinib is an oral Janus kinase inhibitor that is under investigation for the treatment of psoriatic ar
141 oxin (RTX), an ultrapotent agonist of TRPV1, is under investigation for treatment of urinary bladder
142                                         AS01 is under investigation for use in several vaccines in cl
143        For this reason, pharmacologic agents are under investigation in an effort to reduce the need
144              Potential underlying mechanisms are under investigation in animal models and include eff
145               A multitude of novel therapies are under investigation in both the frontline and relaps
146 nd other agents recently approved for adults are under investigation in children.
147 proaches to active and passive immunotherapy are under investigation in clinical trials with the aim
148 talized cell lines, and marrow stromal cells are under investigation in experimental and clinical str
149 bulins, and thrombopoietin receptor agonists are under investigation in lower-risk MDS with thrombocy
150 able safety profiles in phase 2 trials; both are under investigation in ongoing phase 3 trials.
151  T-cell immunity in HIV-1-uninfected persons are under investigation in phase I to III clinical trial
152 g new agents or strategies of immunotherapy, are under investigation in trials enrolling patients wit
153 odobacter sphaeroides of diverse origin have been under investigation in our laboratory for their gen
154 of TRPV1 activation by selective antagonists is under investigation in an attempt to identify novel a
155         The diabetes mellitus drug metformin is under investigation in cardiovascular disease, but th
156  (RAPA), an inhibitor of cytokine responses, is under investigation in humans for graft-vs-host disea
157     Based on these results, this new vaccine is under investigation in phase 3 trials.
158 n-pump inhibitor is an attractive option and is under investigation in the AspECT trial.
159 e remissions in relapsed/refractory ALCL and is under investigation in the first-line setting.
160 ly used in the treatment of trypanosomiasis, is under investigation in the treatment of cancer.
161 outes for their removal from the environment are under investigation, including the use of biodegrada
162                           Now that therapies are under investigation, it is critical that a timely an
163          Gene therapy for ocular disease has been under investigation just over 15 years.
164                  The role of CYP7B1 in brain is under investigation; recent studies show that spastic
165    The roles of fatty acids in the skin have been under investigation since early reports of the phen
166 f MIS on gonadal, prostate, and breast cells is under investigation, the ability of MIS to modulate p
167             Various immunotherapy approaches are under investigation to alleviate or prevent food-ind
168                      Novel P2Y12 antagonists are under investigation to determine whether they can re
169 tes, and dual PPAR-alpha/PPAR-gamma agonists are under investigation to help correct atherogenic dysl
170 s immunomodulation, and reduce allergenicity are under investigation to improve the efficacy and safe
171 rventional approaches have been proposed and are under investigation to modulate neural plasticity, e
172 lear lens extraction and biphakia techniques are under investigation to offer refractive relief to th
173    For this reason, new pharmacologic agents are under investigation to protect the regionally and gl
174      To date, many small molecule approaches are under investigation to target CRAF, yet kinase-selec
175 ion of such new drugs within a CHOP backbone is under investigation to enhance response rates, allow
176 sumption, and rate-responsive pacing therapy is under investigation to improve exercise capacity in h
177 rtages persist, functional machine perfusion is under investigation to improve preservation of the do
178    Active amyloid-beta (Abeta) immunotherapy is under investigation to prevent or treat early Alzheim
179 od derived alpha-DCs in gastroduodenal tract is under investigation to understand whether excess cons
180        The reason for this close association is under investigation using mouse models.
181                       A number of new agents are under investigation with the goal of improving patie
182 ndrogen receptor and glucocorticoid receptor is under investigation with new insights emerging.
183 s such as chemotherapy and radiation therapy is under investigation, with promising results.

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