1 he target sequences should be long enough to
be unique in a given genome.
2 Here, we
are unique in achieving continuous and high-resolution m
3 The Sup35 prion
was unique in allowing Hsp70-independent association of
4 The tongue representation appeared to
be unique in area 3b in that it also received inputs fro
5 These results
are unique in being a broad-scale calculation of the pro
6 However, the indigenous Andaman Islanders
are unique in being ASI-related groups without ANI ances
7 They
are unique in being sporadic, infectious and inherited,
8 Uch37
is unique in being a component of both the proteasome an
9 Thus, this study
is unique in being a direct demonstration that the prese
10 That response
is unique in being a measured manipulation of watershed
11 The cytokinesis protein Blt1p
is unique in being present continuously in nodes from ea
12 Mutant R194C
is unique in being rapidly inactivated at the harsher te
13 ygen cluster that is currently considered to
be unique in biology.
14 ed to other PTPs, KIM-PTPs have E loops that
are unique in both sequence and structure.
15 , whereas the fatty acid metabolic signature
is unique in cardiomyocytes derived from embryonic stem
16 Previously, we demonstrated that TbADAT2/3
is unique in catalyzing two different deamination reacti
17 Tsc1 deletion at this early stage
is unique in causing both seizures and compulsive groomi
18 9H mutation has a poor patient prognosis and
is unique in causing multisystemic smooth muscle dysfunc
19 These heterogeneous system capabilities
are unique in comparison with homogenous systems and pot
20 analysis revealed that ca. 21% of the genome
is unique in comparison to other strains of B. cenocepac
21 This ancient cell type
is unique in containing a giant secretory vesicle derive
22 os, and two cyanobacterial growth scenarios,
is unique in coupling climate projections with a hydrolo
23 The structure
is unique in delineating an ion-occupied ready to conduc
24 These findings
are unique in demonstrating dose-responsive changes in d
25 Our results
are unique in demonstrating that specific components of
26 Parallel to this, we
are unique in demonstrating that the stereotypic glomeru
27 Collectively, our data
are unique in demonstrating that TLR8 is required for se
28 These results
are unique in demonstrating the absolute requirement of
29 Here, we
are unique in describing the use of functionalized multi
30 Humans
are unique in developing large lexicons as their communi
31 Of various conifers, the larch balsam
was unique in displaying a marked TRPC6-prevalent mode o
32 loop (ECL2) and its interaction with ligands
is unique in each G protein-coupled receptor.
33 try remained stable across scanning days and
was unique in each individual in early visual cortex and
34 Coronaviruses (CoVs)
are unique in encoding a 3'-->5' exoribonuclease within
35 ational signatures (E1-E6), and Signature E4
is unique in ESCC linked to alcohol intake and genetic v
36 e neural crest gene regulatory network, thus
being unique in establishing a direct link of upstream e
37 This study
is unique in estimating electricity use for large-scale
38 ected via the loop (26)GQITPETQEK(35), which
is unique in eukaryotic V-ATPases.
39 European Bioinformatics Institute (EMBL-EBI)
is unique in Europe and is one of only two organisations
40 field, we identify an immune signature that
is unique in EVD fatalities.
41 These data
are unique in experimentally confirming the requisite co
42 As Arg183
is unique in family X pols, the design of CXY deoxyribon
43 d2 and its mammalian homologue E4B appear to
be unique in functioning as monomers.
44 expensive, newer generation antimicrobials,
is unique in global health and requires new approaches t
45 (54) (or sigma(N)) associated RNA polymerase
are unique in having conserved positions around -24 and
46 Copper-ATPase ATP7A
is unique in having a sequence rich in histidine and met
47 The zebrafish neuromuscular junction
is unique in having a very small quantal content and a h
48 The P2X7 receptor
is unique in having an intracellular carboxyl-terminal c
49 Thus, the ASE class
is unique in having both an on-cell and an off-cell.
50 This new species
is unique in having both narrow and cylindrical-to-sligh
51 Budding yeast
is unique in having only one kinetochore microtubule att
52 The interleukin 12 (IL-12) family
is unique in having the only heterodimeric cytokines, in
53 The vertebrobasilar system (VBS)
is unique in human anatomy in that two arteries merge in
54 The Th1 cytokine interferon-gamma
was unique in inducing Shh expression in astroglia and N
55 ing naive CD4(+) T cells, suggesting that DC
are unique in initiating T cell-dependent Ab responses.
56 BFDCA
is unique in integrating various aspects of DC patterns
57 H. pylori Fur
is unique in its ability to activate and repress gene ex
58 TAT1 or STAT2 protein, mumps virus V protein
is unique in its ability to also target STAT3 for ubiqui
59 pears from results of this study that Mg(2+)
is unique in its ability to assist efficiently the gener
60 ps is a robust and scalable platform, and it
is unique in its ability to capture and profile >75% of
61 ral bacterial pathogens tested, P gingivalis
is unique in its ability to citrullinate proteins.
62 n particular, the cranial neural crest (CNC)
is unique in its ability to contribute to both facial sk
63 The control method
is unique in its ability to detect single-molecule compl
64 nt than other Candida species, C. lusitaniae
is unique in its ability to develop resistance to amphot
65 ing statistical confidence measures, qvality
is unique in its ability to estimate both types of score
66 It
is unique in its ability to examine materials in real ti
67 The Kv2.1 voltage-gated potassium channel
is unique in its ability to form large clusters in the p
68 This virus
is unique in its ability to lethally infect both mammals
69 isease, angiogenesis, and insulin signaling,
is unique in its ability to produce hydrogen peroxide co
70 ditional imaging modalities, this technology
is unique in its ability to provide real-time feedback t
71 In contrast, FMRP
is unique in its ability to recognize G-quadruplexes, su
72 In the immune system, miR-155
is unique in its ability to shape the transcriptome of a
73 Of all tRNAs, initiator tRNA
is unique in its ability to start protein synthesis by d
74 ing three symmetry-equivalent lactone rings,
is unique in its ability to undergo highly selective and
75 Acidovorax sp. strain JS42
is unique in its ability to use 2-nitrotoluene as a sole
76 ell-conserved cosubstrate binding pocket but
is unique in its active site and putative alpha-tubulin
77 It
is unique in its application potential by making possibl
78 Among animals, Homo sapiens
is unique in its capacity for widespread cooperation and
79 It
is unique in its capacity to functionalize all types of
80 e that platelet-derived growth factor (PDGF)
is unique in its capacity to promote cell migration.
81 y, cardiovascular magnetic resonance imaging
is unique in its comprehensive tissue characterization,
82 nd extensible neuron classification endeavor
is unique in its detail, utility, and completeness.
83 2-oxidase (P2O), a flavoenzyme oxidase that
is unique in its formation of C4a-hydroperoxyflavin, was
84 Pd(DMSO)2(TFA)2
is unique in its high chemoselectivity for the conversio
85 RGS2
is unique in its in vitro potency and selectivity as a G
86 Mig-7 is an example of an atypical gene that
is unique in its induction, translation and apparent car
87 Each of the anti-adaptors
is unique in its interaction with RssB and sensitivity t
88 ound in abundance in all cells in nature, it
is unique in its likely role in the origin and survival
89 Although every viral IFN antagonist
is unique in its own right, four main mechanisms are emp
90 Panx1
is unique in its permeability to molecules up to 1 kDa i
91 It
is unique in its presentation and course.
92 Therefore, the ICP27 RGG box
is unique in its recognition of nucleic acid sequences c
93 unknown, and it has been suggested that HER2
is unique in its requirement for phosphorylation of Y877
94 The liver
is unique in its response to injury, simultaneously unde
95 The human Eg5 (HsEg5) protein
is unique in its sensitivity to allosteric agents even a
96 One alternative sigma factor, sigma(N),
is unique in its structure and functional mechanism, for
97 Our approach
is unique in its utilization of short reads only from 16
98 essed the transcription factor RORgammat and
was unique in its ability to generate all known ILC subs
99 The survey
was unique in its size, broadness and level of detail.
100 The material system
is unique in many ways, demonstrating for the first time
101 idized by AMADHs, meaning that these enzymes
are unique in metabolizing and detoxifying aldehyde prod
102 B. burgdorferi is known to
be unique in metal utilization, and little is known of t
103 The Tmem67(tm1(Dgen/H)) line
is unique in modelling the variable expressivity of phen
104 This study
is unique in nature as it is mediatorless, economical an
105 nzymes from marine sponges (phylum Porifera)
is unique in nature for catalyzing the formation of inor
106 In mammals, Rem2 has been found to
be unique in not only its structure, but also its tissue
107 CTD
is unique in numerous respects: curation focuses on envi
108 (Georgia), dated to 1.77 million years ago,
is unique in offering detailed insights into patterns of
109 eptor tyrosine kinases (RTKs), Eph receptors
are unique in possessing a sterile alpha motif (SAM doma
110 om Mycobacterium tuberculosis (GlmU(Mtb)) to
be unique in possessing a 30-residue extension at the C
111 Thus, among four Ras proteins, K-Ras4A
is unique in possessing a dual membrane-targeting motif.
112 Each axoneme
is unique in possessing a long, cytoplasmic portion as w
113 is distantly related to all other fungi, and
is unique in possessing both EF-1alpha and EFL genes.
114 Of the four human CCR8 ligands, CCL1
is unique in potentiating Treg cells.
115 Here, we
are unique in presenting a murine ischemic wound model t
116 We
are unique in presenting clear demonstration that gamma-
117 In summary, these results
are unique in presenting evidence demonstrating that the
118 Among echolocating vertebrates, odontocetes
are unique in producing high-frequency vocalizations at
119 The action of AMPs on spheroplasts
is unique in producing an intracellular fluorescence int
120 or symmetric dimethylarginine (SDMA), PRMT7
is unique in producing solely monomethylarginine (MMA) p
121 The sigma(54) promoters
are unique in prokaryotic genome and responsible for tra
122 dies from a breast cancer patient with lupus
were unique in protecting rat hippocampal neurons from g
123 The results presented herein
are unique in providing a complete picture of the chemic
124 Taken together, our results
are unique in providing a comprehensive understanding of
125 Our findings
are unique in providing an animal model to decipher the
126 These results
are unique in providing causal evidence that the posteri
127 These data
are unique in providing evidence of the biological signi
128 disorders for over two decades, our results
are unique in providing genetic evidence for a significa
129 ulum to the plasma membrane (ER-PM junction)
is unique in providing a direct communication link betwe
130 EMAGE
is unique in providing both text-based descriptions of g
131 This study
is unique in providing genome-wide evidence of distinct
132 Taxonomer
is unique in providing integrated nucleotide and protein
133 combination with site-directed spin labeling
is unique in providing nanometer-range distances and dis
134 The server
is unique in providing output for multiple alternative r
135 linear, peptide-like epitope, but one clone
was unique in recognizing a conformational epitope.
136 ADAM10 substrate N-cadherin, whereas Tspan14
was unique in reducing cleavage of the platelet collagen
137 We
are unique in reporting a repetition of Bateman using hi
138 Furthermore, we
are unique in reporting increased serine and glycine bio
139 We
are unique in reporting that asTF, but not flTF, strongl
140 These findings
are unique in representing a reported case of SCID cause
141 d any of these placental mammal clades would
be unique in representing a confirmed Mesozoic record of
142 These disorders
are unique in requiring exposure to a severe stressor, w
143 lation of TCRalphabeta-expressing cells that
are unique in several respects.
144 Among extant tetrapods, salamanders
are unique in showing a reversed preaxial polarity in pa
145 These results
are unique in showing that the effects of acidic deposit
146 USP21
is unique in showing clear association with both centros
147 To the best of our knowledge, this report
is unique in showing that exposure to a persistent patho
148 The psychotic major depression group
was unique in showing greater activation than both other
149 dicting response in all febrile patients and
was unique in showing increased levels among nonresponde
150 el plant Arabidopsis (Arabidopsis thaliana),
were unique in showing NLR expression skewed toward the
151 provides preclinical evidence that ON123300
is unique in simultaneously inhibiting key oncogenic pat
152 This PrD
is unique in size and composition: glutamine free, aspar
153 Spiders
are unique in synthesizing many different kinds of silk,
154 We show that MyoVc
is unique in taking variable size steps, which are frequ
155 st surface loops, H16.U4 monoclonal antibody
is unique in targeting the C-terminal arm of the L1 prot
156 red around intermetallic nanocrystals, which
are unique in terms of long-range atomic ordering, well-
157 CuFeS2 QDs
are unique in terms of their composition.
158 We show that each cancer
is unique in terms of its cellular organization, molecul
159 the populations in the Arabian Peninsula, it
is unique in terms of its relative high Asian genetic co
160 Each of the mutant proteins studied
is unique in terms of the properties of the MBD and the
161 of the last century or more, the 1980s event
was unique in terms of its global scope and scale; our o
162 Our findings
are unique in that a dominant role could be ascribed to
163 However, these results
are unique in that all these functions are detected in t
164 These subgroups
are unique in that each has experienced a long and persi
165 Smooth muscles
are unique in that force generation requires both intera
166 Cadherin repeats arranged in series
are unique in that linker regions also feature calcium-b
167 Prostate cancer (PCa)bone metastases
are unique in that majority of them induce excessive min
168 h insulins than to the molluscan hormone and
are unique in that posttranslational modifications chara
169 a prototype of early prosimian primates but
are unique in that sublaminae of striate cortex layer IV
170 t and weight in children with achondroplasia
are unique in that there is no overlap in the height dis
171 Hyaluronan synthases (HAS1-3)
are unique in that they are active only when located in
172 nt growth and development, mechanical forces
are unique in that they are an intrinsic result of cellu
173 n imposed loss in cell size, however T-cells
are unique in that they do not have a RVI response.
174 KSHV) and rhesus macaque rhadinovirus (RRV),
are unique in that they express viral homologues to cell
175 ins, family II pyrophosphatases (CBS-PPases)
are unique in that they generally contain an additional
176 pecies, members of the Bacillus cereus group
are unique in that they have a total of four cid-/lrg-li
177 Our cases
are unique in that they included 1 case of a superficial
178 alimentary canal, those of the adult corpus
are unique in that they lie close to the lumen and incre
179 Primate lentiviruses
are unique in that they produce several accessory protei
180 Polyfunctional ionogenic compounds
are unique in that they sorb to environmental solids at
181 are the antagonists GASP-1 and GASP-2, which
are unique in that they specifically antagonize myostati
182 The present findings
are unique in that they were obtained in systemically eu
183 Membrane fusion of hMPV appears to
be unique, in that fusion of some hMPV strains requires
184 This reaction
is unique in that 1) both 11-cis-retinol and all-trans-r
185 However, PKCdelta
is unique in that activation loop (Thr(507)) phosphoryla
186 us domains, it is suggested that the hPgn K3
is unique in that all other K3-type domains, including h
187 ng both induce a strong T cell response that
is unique in that among responding CD8 T cells, a T effe
188 The VEGA browser
is unique in that annotation is updated via the Human An
189 The case described herein
is unique in that anti-TNF-induced autoimmune disease oc
190 Human kinesin-14 KIFC1
is unique in that cancer cells with amplified centrosome
191 This pathway
is unique in that every major node is frequently mutated
192 of Bacteroides fragilis and related species
is unique in that extracytoplasmic proteins are glycosyl
193 Our system
is unique in that fibrillar tau forms without external m
194 The salticid visual system
is unique in that high-acuity and motion vision are proc
195 The first meiotic division
is unique in that homologous pairs of sister chromatids
196 This compound
is unique in that in the solid state it undergoes revers
197 By contrast, salty taste
is unique in that increasing salt concentration fundamen
198 halotolerant green alga Dunaliella bardawil
is unique in that it accumulates under stress two types
199 m of an endogenous apoptosis-inducing ligand-
is unique in that it activates two related proapoptotic
200 This labeling approach
is unique in that it allows myoVa, instead of its cargo,
201 Positron emission tomography (PET)
is unique in that it allows quantification of biochemica
202 This molecule, termed 2'3'-cGAMP,
is unique in that it binds to the adaptor protein STING
203 This assay
is unique in that it can effectively distinguish endopep
204 tion as transcriptional repressors, SMU.1349
is unique in that it can function as both.
205 Among all enzymes in nature, RNase P
is unique in that it can use either an RNA- or a protein
206 wuHMM
is unique in that it can utilize sequence divergence inf
207 Oral cancer
is unique in that it causes intense pain at the primary
208 The clade Aplanulata
is unique in that it comprises mostly solitary species,
209 -molecule RNA construct studied in this work
is unique in that it contains all of the structural elem
210 onal epithelium lining the vomeronasal organ
is unique in that it contains stem cells capable of gene
211 The behavior
is unique in that it depends neither on the nature of th
212 G(PA)C
is unique in that it enables real-time tracking of selec
213 es encoding DNA ligases (LIG), the LIG3 gene
is unique in that it encodes multiple DNA ligase polypep
214 Its eruption
is unique in that it exceeded the Eddington luminosity l
215 The countermeasure by influenza B virus
is unique in that it exhibits species specificity.
216 This approach
is unique in that it focuses on efficient localized, iso
217 Calbindin-D28k
is unique in that it functions as both a calcium buffer
218 pre-mRNA undergoes alternative splicing, but
is unique in that it harbors a rare twintron whereby one
219 Claudin-7
is unique in that it has a stronger basolateral membrane
220 cally important pathogen Helicobacter pylori
is unique in that it has been shown to function as a rep
221 Ag recognition by T cells
is unique in that it involves a coreceptor that binds at
222 ike other reverse transcriptases, telomerase
is unique in that it is a ribonucleoprotein complex, whe
223 It
is unique in that it is continuously activated at a low
224 14-3-3sigma
is unique in that it is expressed primarily in epithelia
225 Antizyme
is unique in that it is expressed via a novel programmed
226 c, nature of this neovascularization process
is unique in that it is initiated by pericyte and macrop
227 Acetylation of Lys-40 on alpha-tubulin
is unique in that it is located on the luminal surface o
228 Recognition of chi
is unique in that it is recognized as a specific sequenc
229 scularization, the developing nervous system
is unique in that it is secondarily vascularized by spro
230 Ssu72
is unique in that it is specific for Ser(P)(5) in one or
231 This enzyme
is unique in that it is the first hydroxymethylglutaryl
232 The LLDp
is unique in that it is the first place of binaural conv
233 modified sites, histone H3 lysine 56 (H3K56)
is unique in that it lies within the globular core domai
234 3DCOMB
is unique in that it makes use of both local and global
235 Our system
is unique in that it monitors both content and lipid mix
236 This joint EC analysis
is unique in that it not only uses residue coevolution i
237 cessing figurative language, such as idioms,
is unique in that it requires one to make associations b
238 Our institution
is unique in that it rests at an intersection of two of
239 Our institution
is unique in that it rests at an intersection of two of
240 activating Ly49H receptor of mouse NK cells
is unique in that it specifically recognizes a virally e
241 The TBSGC
is unique in that it uses biological importance as a pri
242 TRPV3
is unique in that its activity is sensitized upon repeti
243 The T cell antigen receptor (TCR)
is unique in that its affinity for ligand is unknown bef
244 entameric ligand-gated ion channels (pLGICs)
is unique in that its members display opposite permeant-
245 This mechanism of action
is unique in that no other approved antidiabetic drugs a
246 of YfcG suggests that the reductase activity
is unique in that no sulfhydryl groups in the YfcG prote
247 The strawberry fruit
is unique in that the edible flesh is actually enlarged
248 This on-chip assay
is unique in that the extraction can be automated using
249 However, the behaviour of CrMnFeCoNi
is unique in that the hcp phase is retained following de
250 The UK population
is unique in that the majority of patients have the T60A
251 ical stress can drive chemical reactions and
is unique in that the reaction product can depend on bot
252 somal protein S8 from Aquifex aeolicus (AS8)
is unique in that there is a 41-residue insertion in the
253 This is study in mice
is unique in that two enzymatic activities of pol beta h
254 The reproductive pattern in this complex
is unique, in that the female reproduces once and then d
255 thin the striatum, but this neurotransmitter
is unique, in that variation in dopamine tone is likely
256 A fifth position (alpha3Glu113)
was unique in that it discriminated between the two comp
257 However, (BDI)Al
was unique in that it exhibited a low-energy feature tha
258 P65
was unique in that it was not constitutively active but
259 lanet Sedna was discovered ten years ago and
was unique in that its closest approach to the Sun (peri
260 Plants
are unique in the apparent involvement of both a family
261 Niobium polyoxometalates (Nb-POMs)
are unique in the aqueous metal-oxo cluster landscape in
262 the knowledge of cortical microcircuitry and
are unique in the number of connections reported and the
263 These unusual features
are unique in the Trypanosomatida and make their Complex
264 of human cultural behavior and one which may
be unique in the animal kingdom.
265 tional activation in the liver that seems to
be unique in the fetus with IUGR.
266 The cumulative nature of human culture
is unique in the animal kingdom.
267 study reveals GH20C to be another tool that
is unique in the arsenal of S. pneumoniae and that it ma
268 PCs or T cells in both human and mice, which
is unique in the B7 family.
269 The field of solid organ transplantation
is unique in the breadth of the standardized data that a
270 re pruning the tree of life in a manner that
is unique in the history of life.
271 ) and K(+) transport by second-site mutation
is unique in the history of Na(+),K(+)-ATPase and points
272 fold but contains an extra beta-hairpin that
is unique in the structures of thermophilic inteins.
273 ive heterotrimer, Lymphotoxin(LT)alpha1beta2
is unique in the TNF superfamily.
274 o distort, bend, and stretch chemical bonds,
is unique in the way it activates chemical reactions.
275 urished from 1945 through the late 1960s and
was unique in the history of comparative psychology.
276 Tonga
was unique in the prehistoric Pacific for developing a m
277 screen uncovered two novel TBP variants that
are unique in their ability to bypass the requirement fo
278 Humans
are unique in their ability to communicate using spoken
279 CD326-CD56+ progenitors
are unique in their ability to generate all mesodermal l
280 Thus, meprin alpha and meprin beta
are unique in their ability to process and release both
281 SMR devices
are unique in their ability to provide mass-based measur
282 Adult urodeles (salamanders)
are unique in their ability to regenerate complex organs
283 Adult urodeles (salamanders)
are unique in their ability to regenerate complex tissue
284 Axolotls
are unique in their ability to regenerate the spinal cor
285 Species of Xenopus and one other amphibian
are unique in their ability to replace a missing lens fr
286 NRG1 isoforms, the type III isoforms of NRG1
are unique in their ability to signal via the intracellu
287 Ceria (CeO2 ) supports
are unique in their ability to trap ionic platinum (Pt),
288 IIIa (APH(2'')) aminoglycoside kinase family
are unique in their ability to utilize GTP as a cofactor
289 TNBC cells
are unique in their dependence on this transcriptional C
290 RV), two closely related gammaherpesviruses,
are unique in their expression of viral homologs of cell
291 n phage genomes, we find that most orthologs
are unique in their genomes (having no diverged duplicat
292 ate receptor family, NMDA-sensitive channels
are unique in their requirement that both glycine and gl
293 pectrally covariant regions of cortex, which
were unique in their spectral signatures, provided a hig
294 OSM
is unique in this family as it can signal using heterodi
295 o imply that the voltage sensor of domain IV
is unique in this linkage and in the ability to initiate
296 The present study
is unique in this regard, in that both neural and behavi
297 and hip joint mobility or that Ichthyostega
was unique in this respect.
298 n systems, the metazoan mitochondrial system
is unique in using a single methionine tRNA (tRNA(Met))
299 characterized RecA modulator proteins, PsiB
is unique in using sequestration as an inhibitory mechan
300 The concept described herein
is unique in utilizing new nucleoside analogues with elo