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2 The observation that the enzyme telomerase is up-regulated in 80-90% of cancer cells isolated from
3 ARHGAP36 isoforms capable of Gli activation are up-regulated in a subset of human medulloblastomas.
4 d fragment corresponding to VPE was found to be up-regulated in a cDNA-AFLP analysis of host response
8 or of death receptor-mediated apoptosis that is up-regulated in a variety of cancers, contributing to
11 bserved that all the secreted protease genes were up-regulated in a rot mutant, and we hypothesized t
13 eticulum stress, apoptosis, and inflammation were up-regulated in ACLF patients, compared to patients
14 n this study, we demonstrate that cytoglobin is up-regulated in activated myogenic progenitor cells,
17 r route of cortisol metabolism in horses and is up-regulated in adipose tissue in obesity in horses,
18 lly, we found that miR-130, whose expression is up-regulated in adipose tissues of DIO mice, could di
19 jasmonate, and jasmonate/ethylene pathways) were up-regulated in ago1 mutants, we demonstrate that j
20 in 2 (PLIN2) is a lipid-droplet protein that is up-regulated in alcoholic steatosis and associated wi
27 nd a 75-kDa NCX1 fragment along with calpain were up-regulated in aortic stenosis patients and rats w
28 lial-mesenchymal transition-associated genes are up-regulated in AR3Tg prostates, suggesting that AR3
29 ults demonstrate that calcineurin expression is up-regulated in areas of high infiltration/migration
32 Astrocyte-derived Neurotrophic Factor (MANF) was up-regulated in autoimmune diseases and inflammatory
33 w that the lymph vessel growth factor Vegf-c is up-regulated in Bacillus Calmette-Guerin- and Mycobac
35 = 0.04) and chemokine receptor 6 (P = 0.004) were up-regulated in biliary tissue of PSC patients with
37 ell growth and differentiation were found to be up-regulated in both the genotypes but more specifica
38 ) regulates various vascular pathologies and is up-regulated in both AD brains and AD mouse models; h
40 aterial, we confirmed that the MADS box gene is up-regulated in both needles and buds of cone-inducin
41 osin heavy chain 7 and natriuretic peptide B is up-regulated in both ventricles with right ventricula
42 ically in transgenic TRPM8(GFP) mouse colon, was up-regulated in both human- and murine-inflamed colo
43 iR-23a-5p, miR-146a-5p and miR-181c-5p) that were up-regulated in both human and rat epileptic tissue
46 PHD isoforms (PHD1, 2, and 3) were found to be up-regulated in C3H10T1/2 cells during RIAD, whereas
49 ein 90 (HSP90) is a molecular chaperone that is up-regulated in cancer and is required for the foldin
51 ne methyl transferase 1 (PRMT1) was shown to be up-regulated in cancers and important for cancer cell
54 ompanied by altered expression of Id2, which was up-regulated in cDC2s and pDCs from conditional knoc
57 of enzymes involved in cartilage degradation was up-regulated in chGRKO but not WT arthritic mice.
58 on, GPD2 and a gene encoding glycerol kinase were up-regulated in Chlamydomonas cells exposed to high
61 mechanical stress causing hypertrophy, Tln1 is up-regulated in CMs and is specifically detected at c
62 emonstrate that the Wnt/beta-catenin pathway is up-regulated in CNS endothelial cells in both human M
65 ness, and epithelial-mesenchymal transition, is up-regulated in colorectal cancer and a number of oth
67 c stress/abscisic acid (ABA)-inducible genes were up-regulated in cpl1-2, and the expression of some
69 -beta receptors and Smad-2/3 phosphorylation were up-regulated in D2J osteoblasts, suggesting that OA
70 nts of C. elegans germ granules (P granules) were up-regulated in daf-2 mutant worms, and knockdown o
74 re, we show that TCF1-mediated transcription is up-regulated in differentiating mESCs and that chemic
78 k type C2 (Npc2), alpha-galactosidase (Gla), are up-regulated in early adipogenesis, and are transcri
79 1,2 pathway, orthologous to Gwl-Arpp19/ENSA, is up-regulated in early G1 and helps promoting START by
80 onal analysis suggested that miR-200b, which is up-regulated in Elavl1Mo KO BMDMs, interacts with mye
82 of neurotensin (NT) and its receptor (NTR1) is up-regulated in experimental colitis and inflammatory
85 and other genes related to the immune system were up-regulated in GAgP, while genes with functions in
89 5 degrees C) stress, HdHIF-1alpha expression was up-regulated in gills at 4h, 24h and 96 h, and in he
90 omoters of microRNAs, previously observed to be up-regulated in GK rat islets, revealed putative CGCG
94 metalloproteinases (MMP-2 and MMP-9), which are up-regulated in heart tissue post-myocardial infarct
95 ha (PDGFRalpha), a tyrosine kinase receptor, is up-regulated in hepatic stellate cells (HSCs) during
96 n, we find that ARF6, MT1-MMP, and kinesin-1 are up-regulated in high-grade triple-negative breast ca
97 tified one and three GPCR-related genes that were up-regulated in highly resistant Culex mosquito str
99 es involved in "DNA mismatch repair" pathway were up-regulated in HPV-positive tumors compared to nor
101 ownregulated whereas EMT-associated proteins were up-regulated in HSP60-knockdowned U87 cells as conf
103 enzymes in U34 mcm(5)s(2)-tRNA modification, are up-regulated in human breast cancers and sustain met
104 Our studies suggest that levels of S1PR3 are up-regulated in human lung adenocarcinomas, at least
106 emical analysis showed that TRAF1 expression is up-regulated in human actinic keratosis and squamous
108 he matrix-specific protein periostin (POSTN) is up-regulated in human cancers and associated with can
110 s cell-cell contacts in epithelial cells and is up-regulated in human colon and gastric adenocarcinom
113 ithin the intronic region of the SPRY4 gene, is up-regulated in human melanoma cells compared to mela
114 lly through PRRs; metallothionein expression was up-regulated in human and mouse intestinal myeloid-d
116 global DNA methylation and NLRP3 expression was up-regulated in human chronic bladder inflammatory t
117 derived alveolar macrophages during fibrosis were up-regulated in human alveolar macrophages from fib
125 -10 was not expressed in healthy corneas but was up-regulated in inflamed corneas by infiltrating mac
131 factor that induces VSMC dedifferentiation, was up-regulated in IRS-1(-/-) mice, and the differentia
134 luding salicylic acid and jasmonic acid also were up-regulated in juvenile primordia; indeed, exogeno
135 inar-specific protein critical for function, is up-regulated in KGM-H via SOCE/NFAT-dependent gene ex
137 e down-regulated, whereas complexes II and V were up-regulated in KO-I/R compared with WT-I/R hearts.
138 encoding MADS box transcriptional regulators are up-regulated in leaves during the meristem transitio
139 ve previously shown that expression of CTRP6 is up-regulated in leptin-deficient mice and, conversely
140 ial carbonic anhydrase genes (CAH4 and CAH5) are up regulated in light, following which their levels
144 m, especially omega-6 fatty acid metabolism, are up-regulated in livers of mice after VSG while genes
145 and the fatty acid ratios of C17:1 and C18:2 were up-regulated in livers of oil-added ducks, while th
150 tabolite transporters were more abundant and were up-regulated in M. populorum growing on poplar wood
153 d molecule that has been shown previously to be up-regulated in many cancers and has been implicated
155 ing the DAPK1 and DAPK3 protein kinases, and is up-regulated in many cancers argues that a pro-surviv
157 throughout oligodendroglial development and is up-regulated in mature oligodendrocytes where it is l
158 Of these transcripts, the majority (54/57) were up-regulated in MD larvae, one of which encoded for
159 preferential translocation partner of HMGA2, was up-regulated in MED12 mutant lesions, suggesting a r
161 , a key regulator of the actin cytoskeleton, is up-regulated in melanoma, though its role in melanoma
165 r of lncRNAs expressed in late spermatocytes are up-regulated in mice deficient in the piRNA pathway.
166 ressed by IL-4 in other cell contexts and to be up-regulated in micro-dissected malignant cells from
168 , actin binding protein, annexin A2 (AnxA2), is up-regulated in migrating IECs and plays an important
169 or 6 (TRAF6), a verified target of miR-146a, was up-regulated in miR-146a(-/-) T cells following allo
170 nes PGC1alpha, PGC1beta, Nrf1, Nrf2 and TFAM were up-regulated in MitoQ- and SS31-treated mutant Htt
171 myelination, including c-Jun, Sox2, and Id2, were up-regulated in Miz1DeltaPOZ mice compared with con
173 nally, the expression of MMP9 and E-cadherin is up-regulated in mouse ESCs--key players in the epithe
174 ne protein in the endoplasmic reticulum that is up-regulated in mouse models of, and brains of patien
176 widely used ovarian cancer biomarker CA125, is up regulated in multiple malignancies and is associat
177 enzyme responsible for GlcCer biosynthesis, was up-regulated in muscle of SOD1(G86R) mice and ALS pa
179 ce prostate-specific membrane antigen (PSMA) is up-regulated in nearly all stages of prostate cancer
180 (Trib3, an ortholog of Drosophila Tribbles) is up-regulated in neurons both in vivo and in vitro Inc
182 rtant member of the BH3-only protein family, is up-regulated in neurons upon toxic beta-amyloid 1-42
184 study, we report that the expression of FUT8 is up-regulated in nonsmall cell lung cancer (NSCLC) and
186 ferase 1 (ST6Gal-I) sialyltransferase, which is up-regulated in numerous cancers, promotes the surviv
188 secreted from adipocytes, and its expression is up-regulated in obese and diabetic mice and humans.
190 gene, which encodes myelin protein zero and is up-regulated in oligodendroglia following axonal inju
191 ation markers and Wnt target gene expression were up-regulated in osteoblast-like cells derived from
198 ical membrane of gastrointestinal epithelia, is up-regulated in patients with inflammatory bowel dise
199 ich were modulated in response to IFN-gamma, were up-regulated in patients with acute Q fever, and th
200 d a spliced form of X-box binding protein 1, were up-regulated in PBMCs from lcSSc patients, with the
201 , we show that GABPalpha, an ETS factor that is up-regulated in PC, is an AR-interacting transcriptio
202 ngs demonstrate for the first time that Pin1 is up-regulated in PD and has a pathophysiological role
204 regulator gene SHORT VEGETATIVE PHASE (SVP) was up-regulated in PnWB-infected C. roseus plants, but
205 co-activator of both CAR and PPARbeta/delta, was up-regulated in Pparbeta/delta(+/+) liver following
207 containing phosphatase 2 (SHP-2), a PTP that was up-regulated in RA, was then analyzed by knockdown u
209 s and drug efflux pumps, but how these genes are up-regulated in response to de-differentiation is no
210 acterium Bacteroides thetaiotaomicron, which are up-regulated in response to rhamnose-containing glyc
211 that only express p47, we demonstrate it to be up-regulated in response to various stimuli, and to c
213 tumorigenic mammary epithelial cells, TRIM29 is up-regulated in response to hypoxic stress but not DN
214 we have found that the endosomal GTPase RhoB is up-regulated in response to inflammatory cytokines an
215 llergic airway diseases, such as asthma, and is up-regulated in response to many asthma-promoting exp
217 plasma membrane of Saccharomyces cerevisiae, is up-regulated in response to several ER stressors and
218 responsive to changes in glucose levels and was up-regulated in response to nicotinamide adenine din
221 -23 and related cytokines have been found to be up-regulated in rheumatoid arthritis, systemic lupus
223 regulated in rth3 and rth5 mutants, while it is up-regulated in rth2 mutants, suggesting that these g
224 sistent with these data, hepatic LDLR levels are up-regulated in SEC24A-deficient cells as a conseque
229 rtantly, CEFIP was located at the z-disc and was up-regulated in several models of cardiomyopathy.
230 We examined whether placental fractalkine is up-regulated in severe early-onset PE and whether the
231 upon the sleep homeostat, as protein levels are up-regulated in short-sleeping mutants and also in w
234 exes contained Alu RNAs, and Alu transcripts were up-regulated in SLE whole blood samples relative to
236 Recently, we discovered that, in addition to being up-regulated in spinal cords of ALS patients, the
237 , and chemokine-chemokine receptor signaling were up-regulated in spleen and drove macrophage alterat
238 h and repressor forms of Gli3, but not Gli2, were up-regulated in Spop mutants, and Ihh target genes
239 olved in the gluten-protein folding process, were up-regulated in superior (SP) and medium (MD) flour
240 ctor A number of putative targets of miR-205 were up-regulated in TECs lacking miR-205, consistent wi
243 oxidative phosphorylation and beta-oxidation are up-regulated in the daw mutants, indicating either a
244 holic steatohepatitis, CCL2 and its receptor are up-regulated in the liver, where they promote macrop
246 ore, endocytic and general trafficking genes are up-regulated in the mature cyst, potentially preserv
247 cytochrome P450 monooxygenases (P450s) that are up-regulated in the R strain are also induced by bot
249 d T1D, GHRH receptor expression was found to be up-regulated in the distal small intestine, a tissue
252 that in atherosclerosis, type VIII collagen is up-regulated in the absence of ApoE and functions to
253 wn for its role in mitochondrial biogenesis, is up-regulated in the absence of phosphatase and tensin
256 tively interferes with lung regeneration and is up-regulated in the emphysematous lungs of patients w
257 ically disordered cancer/testis antigen that is up-regulated in the fetal and diseased human prostate
258 R confirmation, we show that FGF9 expression is up-regulated in the hippocampus of individuals with M
260 e propose a model in which FLOWERING LOCUS T is up-regulated in the leaves under LDs and is then tran
261 the receptor for Stx, globotriaosylceramide, is up-regulated in the presence of butyrate in vitro, we
262 show that recently discovered NRAS isoform 2 is up-regulated in the setting of BRAF inhibitor resista
263 ssue injury, stromal-derived factor-1 (Sdf1) is up-regulated in the wound epidermis and recruits Cxcr
269 nematode's dorsal esophageal gland cell, and was up-regulated in the parasitic second-stage juvenile,
270 ) (Cdkn1c), encoding a cell cycle inhibitor, was up-regulated in the prospective palate of Lhx6(-/-);
272 h in turn controlled neutrophil recruitment, was up-regulated in the skin but absent from the ganglia
273 ranscriptional co-activator binding protein, was up-regulated in the soleus muscle of high sucrose di
274 as connexin43, ZO-1, occludin, and claudin11 were up-regulated in the absence of BT-IgSF, the functio
275 gnaling and inflammatory cytokine expression were up-regulated in the cerebral cortex of patients wit
277 auxin responsive genes promoting leaf growth were up-regulated in the F1 hybrids and hybrid mimics, s
280 thetic genes and bioenergetics-related genes were up-regulated in the high lignin genotype, suggestin
282 ve found that EphB2 transcripts and proteins were up-regulated in the liver, a result likely driven b
284 , including S100A12, S100A9, MMP8, and ARG1, were up-regulated in the peripheral blood of patients wi
287 -UTR and 3'-UTR of four proto-oncogenes that are up-regulated in their transcription, consistent with
289 e 2 immune response in the intestinal mucosa are up-regulated in treatment-naive pediatric patients w
290 e show that carbonic anhydrase (Car) enzymes are up-regulated in type 2-associated progenitor cells a
291 d that genes regulating responses to stimuli were up-regulated in type II cells, while pathways relat
293 eral antigen-presenting machinery components were up-regulated in U251MG cells after demethylating an
295 that >80% of differentially expressed genes are up-regulated in VDR(-/-) KSCs; thus, the VDR is a tr
299 nscription factor Ccm1 and various CAH genes are up-regulated in zinc deficiency, probably due to red
300 alcoholic steatosis in vivo and in vitro and was up-regulated in zone 3 hepatocytes in human alcoholi
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