ライフサイエンスコーパス: beating

1 an the current state-of-the-art method (bead beating).

2 nvestigations of factors controlling ciliary beating.

3 as embryonic lethal within days of the heart beating.

4 e loss of ODAs and severely impaired ciliary beating.

5 ng that increased ASL height but not ciliary beating.

6 ectron microscopy, but with dyskinetic cilia beating.

7 uid/mucus homeostasis and epithelial ciliary beating.

8 ng it with enzymatic crosslinking suppresses beating.

9 dynein arms (ODAs) that power cilia/flagella beating.

10 arms (ODAs), which power cilia and flagella beating.

11 find that CSAP is required for proper cilia beating.

12 discrimination for stimuli with and without beating.

13 critical regulator of ciliary and flagellar beating.

14 nternally generated flows and self-organized beating.

15 tion of dynein activity required for ciliary beating.

16 els, absent dynein arms, and loss of ciliary beating.

17 loss of the dynein motors that power ciliary beating.

18 toward the cell as a consequence of ciliary beating.

19 that C1d is essential for wild-type ciliary beating.

20 chloride permeability and increases ciliary beating.

21 serotonergic cells are active when cilia are beating.

22 for characterizing the efficiency of ciliary beating.

23 bute importantly to CSF flow through ciliary beating.

24 e the greatest mechanical force from ciliary beating.

25 ablishing SACOs through to the initiation of beating.

26 ibution within the basal body during ciliary beating.

27 ring vigorous activity such as cardiomyocyte beating.

28 ardiac crescent (stage E7.75) prior to overt beating.

29 our (0.102, p<0.0001), norms justifying wife beating (0.263, p<0.0001), and the extent to which law a

30 The most common alleged abuses were beatings (161 [49.5%]), gunshot wounds (140 [43.1%]), de

31 tic domain, the mechanisms that regulate the beating action of axonemes remain unknown.

32 nsgene-free iPS cells generated reproducible beating activity with robust expression of cardiac alpha

33 use embryo fibroblasts displayed spontaneous beating after 3 wk of induction by Akt plus GHMT.

34 , ERGC seems to be surprisingly good, easily beating all of the competitors.

35 irmed the two-way coupling between flagellar beating and cell-body rocking predicted by our theory.

36 y [Ca(2+)], but only marginally alters cilia beating and cilia-driven fluid velocity within short (~1

37 leted zebrafish revealed compromised ciliary beating and developmental defects.

38 l as for the isolated acoustic properties of beating and harmonicity.

39 ights and addressing norms that justify wife beating and male control of female behaviour.

40 Furthermore, analysis of both flagellar beating and microtubule sliding in vitro demonstrates th

41 nitric oxide production to increase ciliary beating and mucociliary clearance.

42 , except RV-B48 and HCoV-OC43, altered cilia beating and mucociliary clearance.

43 r understanding of the regulation of ciliary beating and mucociliary transport is necessary for ident

44 le for N-DRC integrity in regulating ciliary beating and provide the first direct evidence that mutat

45 able to simultaneously generate both ciliary beating and typical eukaryotic flagellar beating using d

46 mbryonic behavior associated with comb cilia beatings and initial muscle organization does not requir

47 g optimized cellular lysis by extensive bead beating) and chromatographic conditions (specifically, 3

48 cated in protective airway reflexes, ciliary beating, and bronchodilation.

49 ate the CFTR Cl(-) channel, increase ciliary beating, and initiate cytokine secretion.

50 mechanism that produces asymmetric flagellar beating, and pose a new challenge for the functional stu

51 ed based upon their beating frequency, their beating angle, and their distinct localization within th

52 pproximately 3-5-fold, and increases ciliary beating approximately 20-50%.

53 In ciliary swimmers, ciliary beating, arrests, and changes in beat frequency are ofte

54 y monitoring bacterial motion and heart-cell beating as well as detecting infrasound power in solutio

55 ethod to measure ATP consumption of actively beating axonemes on a single-cell level.

56 tamylase TTLL6 was necessary for coordinated beating behavior.

57 rientation aligns to ensure coherent ciliary beating, but the mechanisms that maintain BB orientation

58 ate cerebrospinal fluid flow through ciliary beating, can cause hydrocephalus.

59 rpose of this study was to determine, in the beating canine heart, the relationship between CF and ra

60 well as the contractile strains produced by beating cardiac muscle cells can be optimized by substra

61 stimulation or the patch-clamp technique in beating cardiac myocytes, we identified a neuronal NO sy

62 thin 3 min of beta-adrenergic stimulation in beating cardiac myocytes.

63 mouse tail-tip and cardiac fibroblasts into beating cardiac-like myocytes in vitro.

64 A beating cardiomyocyte culture generated from induced plu

65 ; (2) 2-dimensional in vitro models, such as beating cardiomyocyte monolayers or small clusters of hu

66 Embryoid body formation yielded beating cardiomyocyte-like cells, which expressed early

67 nt stem cells (hiPSCs) and differentiated to beating cardiomyocytes (CMs).

68 nt-specific and control-iPSCs, spontaneously beating cardiomyocytes (iPSC-CMs) were observed.

69 onic stem cells were first differentiated to beating cardiomyocytes a decade ago, interest in their p

70 In these protocols, beating cardiomyocytes can be induced from mouse fibrobl

71 ays, additionally forming vascular tubes and beating cardiomyocytes in a fusion-independent manner; a

72 ntial mechanodynamic characteristics of self-beating cardiomyocytes including the contractile amplitu

73 Feedback of beating cardiomyocytes on the expression of matrix by fi

74 CaCLEAN combined with 3D confocal imaging of beating cardiomyocytes provides a functional 3D map of a

75 When coupled to spontaneously beating cardiomyocytes via connexin-43-containing gap ju

76 osed to Activin differentiate precisely into beating cardiomyocytes without further treatment.

77 of fundamental properties of ECC couplons in beating cardiomyocytes without pharmacological intervent

78 They fail to form beating cardiomyocytes, generate neurons poorly, form sm

79 nto three main cardiac lineages: functional, beating cardiomyocytes, smooth muscle, and endothelial c

80 07 mm could supply basic energy needs in non-beating cardiomyocytes, suggesting that increased collat

81 In beating cardiomyocytes, synchronized localized Ca(2+) tr

82 cification of anterior-like endothelium into beating cardiomyocytes.

83 enic precursors that generated spontaneously beating cardiomyocytes.

84 5(+) and Isl1(+) CPCs, leading to a sheet of beating cardiomyocytes.

85 ntration, showing autoregulation of Na(+) in beating cardiomyocytes.

86 and quality of cell conversion; we observed beating cells as early as 1 week after reprogramming com

87 ral-GMT and shortened the duration to induce beating cells from 30 to 10 days in mouse fibroblasts.

88 We acquired videos of single beating cells, of microbead displacement during contract

89 esia (PCD), a congenital disorder of ciliary beating, characterized by recurrent infections of the up

90 ithelia containing multiciliated cells align beating cilia along a common planar axis specified by th

91 olarity (PCP) whereby MCCs align hundreds of beating cilia along a common planar axis.

92 e mediators and phasic stresses generated by beating cilia and air drag forces.

93 Inverted ALIs exhibit beating cilia and mucus production, consistent with conv

94 r and decreased both CBF and total number of beating cilia by 6 hours.

95 in the cell body and then transduced to the beating cilia by membrane depolarization.

96 Ciliated surfaces harbouring synchronously beating cilia can generate fluid flow or drive locomotio

97 ting the complex waveforms characteristic of beating cilia requires the coordinated activity of multi

98 ted in the early appearance of spontaneously beating clusters.

99 his is ~10-fold softer than adult heart, the beating contractions of E4 cardiomyocytes prove optimal

100 define reversible local conduction blocks in beating cultures without influencing the propagation act

101 the microscopic motion of cilia during their beating cycle.

102 eins were motile and did not exhibit obvious beating defects.

103 rom 30 kg Yorkshire pigs in a model of heart-beating donation and either preserved in cold histidine-

104 Uncontrolled non-heart-beating donor (UNHBD) transplantation offers a major opp

105 ion will be highly significant for non-heart-beating donor cells.

106 P is feasible and safe in good quality heart-beating donor kidney grafts.

107 ic ex vivo kidney perfusion (NEVKP) in heart-beating donor kidney transplantation.

108 which will advance the utility of non-heart-beating donor organs for cell therapy or other applicati

109 We studied non-heart-beating donor rats for global gene expression with Affym

110 inferior to those of hepatocytes from heart-beating donors (P < 0.05).

111 this was inferior to hepatocytes from heart-beating donors (P < 0.05).

112 Liver grafts procured from heart-beating donors and preserved by SCS served as controls.

113 Organs from non-heart-beating donors are attractive for use in cell therapy.

114 milarly, although hepatocytes from non-heart-beating donors engrafted and proliferated after transpla

115 Consent for cornea donation from non-heart-beating donors is often requested by means of telephone

116 ecular changes in hepatocytes from non-heart-beating donors offer opportunities for improving donor c

117 iling in hepatocytes isolated from non-heart-beating donors showed far greater perturbations compared

118 -label, monocenter trial, 160 deceased heart-beating donors were allowed to perform 236 renal transpl

119 transplantations, split grafts, or non-heart-beating donors were not included.

120 strategies, such as live donation, non-heart-beating donors, and expanded criteria donors.

121 r prolonged periods after death in non-heart-beating donors, but extensive molecular perturbations fo

122 y isolated viable hepatocytes from non-heart-beating donors, especially up to 4 hours after death, al

123 In non-heart-beating donors, liver tissue was morphologically intact

124 oxygenation during HMP of kidneys from heart beating donors.

125 ter death, respectively, compared with heart-beating donors.

126 ilia polarity as well as the timing of cilia beating during metachronal synchrony.

127 close frequencies whose interaction leads to beating effects responsible for the grand cycles (350-40

128 x providing a direct assessment of the cilia beating efficiency.

129 etabolism and abnormal PPAR-gamma pathway in beating embryoid bodies (EBs) with defined media, we est

130 Pharmacological responses of beating embryoid bodies exposed to a comprehensive panel

131 Here, we focus on the spontaneously beating embryonic heart and sparsely cultured cardiomyoc

132 nerating the force for ciliary and flagellar beating essential to movement of extracellular fluids an

133 rises from hydrodynamic interactions between beating filaments.

134 to simultaneously feed is due to constantly beating flagella or appendages that are positioned eithe

135 ates by more than an order of magnitude; the beating flagellum is simply unable to draw enough water

136 ves rise to a thickness-independent temporal beating for transmitted pulses, an analogue of Zitterbew

137 ed to stabilize basal bodies against ciliary beating forces.

138 s of Volvox carteri, with distinct intrinsic beating frequencies, are studied by high-speed imaging a

139 erating a liquid phase that improves ciliary beating frequency at the lung epithelial surface, and al

140 me that oral gavage of ethanol decreased the beating frequency of all three types of ependymal cilia

141 The beating frequency of each cardiac spheroid could be read

142 per power stroke of ~354 microm and average beating frequency of ~1.5 Hz.

143 , disrupted sarcomere assembly and decreased beating frequency, contractile movement, amplitude of fi

144 -II and type-III classified based upon their beating frequency, their beating angle, and their distin

145 n the ATP consumption rate and the flagellar beating frequency, with approximately 2.3 x 10(5) ATP mo

146 , to measure whether the potential for heart-beating (HB) deceased donors was adequately converted to

147 rucial role in the normal functioning of the beating heart and to be necessary to maintain mitochondr

148 ventricular biopsies were harvested from the beating heart during identical infusions to measure myof

149 s serial in vivo fluorescence imaging of the beating heart in live mice in both confocal and nonlinea

150 g of a GFP-labeled (myl7:GFP zebrafish line) beating heart in real time at 24-31 h post-fertilization

151 able imaging at the single-cell level in the beating heart in the mouse.

152 NIMR can successfully be created in a beating heart swine model and results in dilatation and

153 ive energy sources remains superior to other beating heart techniques.

154 uorescently labeled cells and vessels in the beating heart tissue through a small incision made in th

155 The NeoChord DS 1000 system enables off-pump beating heart transapical MV repair with implantation of

156 stem, capable of viable integration with the beating heart via medical sutures and operation with eff

157 ide-modified hydrogel can be injected in the beating heart where it remains localized for a clinicall

158 e ability to provide real-time images of the beating heart with good temporal resolution, combined wi

159 In the beating heart, cardiac myocytes (CMs) contract in a coor

160 operative strategies (off-pump, on-pump with beating heart, on-pump with arrested heart, on-pump with

161 ophila melanogaster embryo and a Danio rerio beating heart.

162 nd manipulating tools and devices inside the beating heart.

163 enable reconstructive procedures inside the beating heart.

164 dioport video-assisted imaging system in the beating heart.

165 lene (ePTFE) cords on mitral leaflets in the beating heart.

166 sly map Vm and epicardial contraction in the beating heart.

167 G (0.14% [95% CI, 0.029%-0.40%]) and on-pump beating-heart CABG (0% [95% CI, 0%-1.6%]), intermediate

168 Beating-heart image-guided intracardiac interventions ha

169 A novel device used for beating-heart image-guided MV repair demonstrates a sign

170 Transesophageal echocardiography-guided beating-heart MV repair with expanded polytetrafluoroeth

171 oronary-artery bypass grafting (CABG) with a beating-heart technique (off-pump CABG), as compared wit

172 tery bypass grafting (CABG) performed with a beating-heart technique (off-pump) and those who underwe

173 tional aortic valve anatomy is important for beating-heart transcatheter aortic valve implantation.

174 laments was constitutively phosphorylated in beating hearts at a site that inhibits MLCP activity.

175 Furthermore, using time-lapse imaging of beating hearts in conjunction with a Cdh2 tandem fluores

176 In beating hearts, phosphorylation of myosin regulatory lig

177 Thus, through detailed 4D imaging of beating hearts, we have identified novel cellular behavi

178 zing lineage specification and creation of a beating human cardiac microchamber confined by the patte

179 han 10-fold increase in the number of mature beating iCM loci.

180 ene Bmi1 significantly enhanced induction of beating iCMs from neonatal and adult mouse fibroblasts.

181 SeV-GMT generated 100-fold more beating iCMs than retroviral-GMT and shortened the durat

182 A combination of 5 min of bead beating in 70% EtOH followed by a 10-min room temperatur

183 f basal bodies against the forces of ciliary beating in addition to its separable role in basal body

184 r odorant ligands robustly activate flagella beating in an Orco-dependent process.

185 rils and to analyze loss of synchronicity of beating in cells with contractile defects.

186 ency almost 10-fold--compared with cilia all beating in phase.

187 Fluid forces are sufficient to keep flagella beating in synchrony.

188 s been widely believed to be the product of "beating": interference between frequency components in t

189 This is suggested by mode beating involving vibrations beyond the excitation spect

190 Coordination of ciliary beating is essential to ensure mucus clearance in the ai

191 they continue to mature over 2 months before beating is observed.

192 Synchronized beating is required to swim both fast and straight.

193 ndicates that, contrary to classic theories, beating is unlikely to underlie consonance.

194 y clearance, driven by the engine of ciliary beating, is the primary physical airway defense against

195 arameters associated with the morphology and beating kinematics of the whirligig beetle's legs in swi

196 ndividual in a school, as well as their tail-beating kinematics.

197 oth new insights, to our knowledge, into the beating mechanism of flagella and a powerful tool for fu

198 yocytes (hESC-CMs) to study their autonomous beating mechanisms.

199 n critical processes as diverse as flagellar beating, membrane trafficking, histone methylation, and

200 The combination of a fast and simple bead-beating module for the disruption of the bacterial cell

201 ution imaging to characterize MT behavior in beating mouse myocytes.

202 g acquisition algorithm for the imaging of a beating murine heart at the single-cell level.

203 high temporal and spatial resolution in the beating murine heart, allowing visualization of individu

204 Here, we report a method for imaging beating murine hearts using intravital 2-photon microsco

205 rdiac differentiation, forming spontaneously beating myocytes in vitro; cre/LoxP fate mapping identif

206 tterned so that it connected 2 independently beating neonatal rat ventricular cardiomyocyte monolayer

207 suit, (2) a low-amplitude ipsilesional right-beating nystagmus without fixation, (3) gaze-holding def

208 e is in excellent agreement with vibrational beating observed in time-resolved spectroscopy experimen

209 ate that a plasma undulator generated by the beating of a mixture of high-order laser modes propagati

210 ch different functions as the high-frequency beating of a wing in a hummingbird, the dilation of the

211 The periodic beating of an isolated flagellum from Chlamydomonas rein

212 , therefore, play a role in coordinating the beating of cilia and flagella.

213 ll shape and size, misplacement and abnormal beating of cilia, blebbing of the microvilli.

214 by the core PCP proteins is the directional beating of cilia, such as those in the vertebrate node,

215 We conclude that beating of ependymal motile cilia is not tightly regulat

216 with experiment suggests that the correlated beating of heart cells may be limited by the structural

217 The mechanism that drives the regular beating of individual cilia and flagella, as well as den

218 m described here could provide insights into beating of isolated eukaryotic cilia and flagella, as we

219 The beating of motile cilia and flagella enables cells to sw

220 The beating of motile cilia generates fluid flow over epithe

221 ult of leftward flow generated by asymmetric beating of nodal cilia, which eventually induces asymmet

222 The resulting characteristic beating of populations and quantum coherences is in good

223 axonemal dyneins, the motors that drive the beating of the axoneme, nor whether the effects on motil

224 ransport along microtubules and the rhythmic beating of the axoneme.

225 uted to forward propulsion combined with the beating of the flagella pairs.

226 However, vital functions such as beating of the heart cause pulsations in brain tissue, l

227 ate essential processes of life, such as the beating of the heart.

228 undary conditions that determine the form of beating of the ventral flagella.

229 essitates mechanical disruption through bead beating or sonication, using benchtop instruments that r

230 arm and hand) was performed in 9 human heart-beating organ donors.

231 on alters mitral annular strains in a normal beating ovine heart preparation.

232 al band, increased AML strains in the normal beating ovine heart.

233 In healthy, beating ovine hearts, annuloplasty rings (COS, RSA, PHY,

234 simultaneously visualize the temporal cilia beating pattern which plays critical roles in cilia func

235 ty remain elusive, such as the regulation of beating patterns and the energetic efficiency of these n

236 thelial cells had stiff and dyskinetic cilia beating patterns compared to control cells.

237 e--both of which are prototypical of general beating patterns observed in eukaryotes.

238 tificial cilium that could mimic the complex beating patterns of its biological counterpart.

239 the functional significance of the observed beating patterns remain unresolved.

240 self-assemble into active bundles exhibiting beating patterns reminiscent of those found in eukaryoti

241 The affected individual had altered cilia beating patterns, and no detectable ultrastructural defe

242 To create regular, oscillatory beating patterns, the activities of the axonemal dyneins

243 ed for Hcn4-GFP expression does not generate beating PM cells due to inadequate sarcomeric protein ex

244 uth Pole and throughout Antarctica by 1889 - beating polar explorers by more than 22 years.

245 CL prolongation and dysrhythmic spontaneous beating (produced by cytosolic Ca(2+) buffering) and an

246 Ciliary beating produces asymmetric mechanical forces that are r

247 Ciliary beating produces quasi-steady arrays of counterrotating

248 The forces generated by ciliary beating promote basal body disassembly in bld10Delta cel

249 ic electrical signals regulate the intrinsic beating properties of cardiomyocytes.

250 ented acute rejection and preserved palpable beating quality with reduced CD8 T-cell graft infiltrati

251 imulating engraftment of fibrin patches onto beating rat ventricular myocytes exposed to hypoxia show

252 potentiated doxorubicin-induced decrease in beating rate and amplitude of iPS-derived cardiomyocytes

253 with amiodarone, L-ala,SP prodrugs increased beating rate and decreased beat amplitude in human induc

254 r cardiomyocyte differentiation capacity and beating rate and suppressed the smooth muscle cell forma

255 increased and carbamylcholine decreased the beating rate in both hESC-CMs and iPSC-CMs.

256 In sinoatrial node cells of the heart, beating rate is controlled, in part, by local Ca(2)(+) r

257 +57%) and acetylcholine decreases (-23%) the beating rate of CD166-selected cells, which express the

258 In a bioassay, 5,6-EET increased the beating rate of neonatal cardiomyocytes.

259 Cardiomyocytes adapt their autonomous beating rate to the frequency at which they were stimula

260 cardiomyocytes are characterised by a lower beating rate, disorganised sarcomeres and sarcoplasmic r

261 N2/AC1, and HCN2 alone were evident in basal beating rate, escape time, and dependence on electronic

262 AC1, these parameters were as follows: basal beating rate: 50+/-1.5, 60+/-5.0, and 129+/-28.9 bpm (P<

263 superior to LV-implanted dogs with regard to beating rates (resting approximately 80 beats/min; maxim

264 spectively, reduced the PV (n=6) spontaneous beating rates from 1.9+/-0.2 to 1.7+/-0.2, 1.6+/-0.2, an

265 spectively, reduced the PV (n=5) spontaneous beating rates from 2.0+/-0.4 to 1.8+/-0.4 and 1.3+/-0.3

266 timal pacemaker properties, defined as basal beating rates of 60 to 90 beats/min, a brisk autonomic r

267 nipulation, PHOX2B::eGFP+ neurons controlled beating rates of cardiomyocytes, and the physical intera

268 Ciliary and flagellar beating requires the coordinated action of multiple dyne

269 combined with high-speed imaging of ciliary beating reveal that the body cilia exert a nearly consta

270 mon model systems, and the complex flagellar beating shapes that power it make its quantitative descr

271 Gata5 directs development of beating sheets of cells that express cardiac troponin T

272 sheltered zones; there, a field of randomly beating short cilia ([Formula: see text]10 [Formula: see

273 The resultant 3D spectrum resolves quantum beating signals arising from excitonic coherences along

274 nstrate control over the presence of quantum-beating signals by packing structurally flexible synthet

275 Understanding the origin of beating signals in the spectra of photosynthetic complex

276 olonged coherence lifetimes revealed through beating signals in the spectra of some systems may resul

277 as such a model system and observed quantum beating signals in their two-dimensional electronic spec

278 and Miller contest our assignment of quantum beating signals observed in the two-dimensional electron

279 se results all support our assignment of the beating signals to electronic coherences.

280 re necessary to enhance the observed quantum-beating signals.

281 le isolated sinoatrial node cells, explanted beating sinoatrial node preparation, telemetric in vivo

282 e system preserves the donor heart in a warm beating state during transport from the donor hospital t

283 h our stiffness measurements at the onset of beating, suggesting that mechanical signaling may initia

284 vation by considering the advantages of tail-beating synchronization between neighbors, which we have

285 hich began generating calcium transients and beating synchronously within 1 day of seeding; the speed

286 teleportation with average fidelity of 0.77, beating the quantum limit by 10 standard deviations.

287 bule-based motor proteins that power ciliary beating, transport intracellular cargos, and help to con

288 icular cardiomyocyte-like action potentials, beating upon electrical stimulation, and evidence of ele

289 ary beating and typical eukaryotic flagellar beating using different pairs of flagella.

290 rements of a Newtonian flow induced by cilia beating (using micro-beads as tracers) and a mathematica

291 odies against the forces produced by ciliary beating via distinct yet interdependent mechanisms.

292 Ciliary beating was visualized, and changes in ciliary beat freq

293 cosity of the aqueous medium led to modified beating waveforms of the axonemes and to higher energy c

294 The beating waves have similar amplitudes but slightly diffe

295 arity, and coordination of metachronic cilia beating, whereas cytoplasmic microtubule dynamics are re

296 the frequencies of sounds generated by their beating wings [5].

297 Overall, we concluded that bead-beating with 80% methanol solution was a good trade-off,

298 A single-photon beating with itself can produce even the most elaborate

299 opy (SPIM), offering pristine views into the beating zebrafish heart.

300 Using 3D time-lapse imaging of beating zebrafish hearts, we observed that the initiatio