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1  This challenge has grown as cancer datasets become increasingly abundant, making them cumbersome to
2                             Cannabis use has become increasingly accepted socially and legally, for b
3 causes of ASD are largely unknown, but it is becoming increasingly accepted that ASD is no longer def
4                               However, it is becoming increasingly accepted that the hepatic ECM prot
5 orm during engulfment of large particles and become increasingly acidic and proteolytic, ultimately f
6 ctures and is one in which the TM-H-Zn angle becomes increasingly acute as the TM-Zn distance decreas
7 orical community data, the sessile community became increasingly algal dominated.
8 s by regulators of proteolytic pathways have become increasingly apparent.
9                                        It is becoming increasingly apparent that a high vasodilator r
10                                        It is becoming increasingly apparent that certain mutations in
11 ics in the activation of the inflammasome is becoming increasingly apparent.
12  structure, function, and dynamics have also become increasingly appreciated.
13 d occurrence and significance of the T6SS is becoming increasingly appreciated, as is its intriguing
14 h as protein kinases and quorum sensing have become increasingly attractive targets for the developme
15  As high-resolution mass spectrometry (HRMS) becomes increasingly available, the need of software too
16 treat mitral and tricuspid valve disease are becoming increasingly available because of the growing n
17          Miniaturized mass spectrometers are becoming increasingly capable, enabling the development
18 ochondria orchestrate catabolic processes by becoming increasingly central energy and metabolic hubs.
19    The problem of accurate IBD detection has become increasingly challenging with the availability of
20 hooting and leak detection of LC systems has become increasingly challenging.
21 e thinner, maintaining a stable polarization becomes increasingly challenging.
22                       In recent years it has become increasingly clear that articular cartilage harbo
23                              Although it has become increasingly clear that cancers display extensive
24                                       It has become increasingly clear that less exposure to microbio
25 es in the area of obesity and cancer, it has become increasingly clear that obesity is a problem that
26 n elucidated over the last few years, it has become increasingly clear that primary monogenetic defec
27 deling events in the etiology of MDD, it has become increasingly clear that replication-independent h
28                                       It has become increasingly clear that the immune system has a s
29                                        It is becoming increasingly clear that alcohol has a significa
30                          Additionally, it is becoming increasingly clear that an organism's microbiom
31                                        It is becoming increasingly clear that cardiac contractility i
32                               However, it is becoming increasingly clear that failure of some patient
33  and advancements in genomic analyses, it is becoming increasingly clear that gene flow between diver
34                                    It is now becoming increasingly clear that NETs also form under no
35                              Moreover, it is becoming increasingly clear that nonrenewable cells, inc
36                               However, it is becoming increasingly clear that plasticity occurs beyon
37                                   It is thus becoming increasingly clear that start codon selection i
38  details vary from species to species, it is becoming increasingly clear that these associations play
39       Treatment with endovascular stents has become increasingly common for the management of vascula
40 ld of emerging infectious diseases, but will become increasingly common in other biological disciplin
41 eneralized anxiety and major depression have become increasingly common in the United States, affecti
42 phores in various natural products, and have become increasingly common reagents for asymmetric incor
43   Assisted reproductive therapies (ART) have become increasingly common worldwide and numerous retros
44 me analyses of single-cell RNA-seq data have become increasingly common.
45 ia glumae, B. gladioli and B. plantarii, are becoming increasingly common across the globe.
46 -dammed lakes at debris-covered glaciers are becoming increasingly common and pose significant outbur
47            Seaweed-dominated coral reefs are becoming increasingly common as environmental conditions
48                        Spinal metastases are becoming increasingly common because patients with metas
49     Fraud in the global food supply chain is becoming increasingly common due to the huge profits ass
50                                    Myopia is becoming increasingly common globally and is associated
51 s to biological systems, an approach that is becoming increasingly common in developmental biology.
52 among women of reproductive age (15-49 y) is becoming increasingly common in many developing countrie
53 s, and the examination of DNA methylation is becoming increasingly common in psychological studies.
54  flow visualization in biological systems is becoming increasingly common in studies ranging from int
55 e costs and decreasing sustainability, it is becoming increasingly common to resort to decision analy
56 recordings from large neural populations are becoming increasingly common.
57 e large-scale clinical genomic data sets are becoming increasingly commonplace, existing miR-TSV pred
58 ges in the WTW topology: since 2003, the WTW becomes increasingly compatible with the picture of a ne
59 tional Institutes of Health (NIH) grants are becoming increasingly competitive in the academic resear
60 of therapies, the management strategies have become increasingly complex.
61                    The modern food system is becoming increasingly complex and globalized, but models
62 sis based on real-time PCR (qPCR) methods is becoming increasingly complex and laborious.
63 ting the mechanisms of CME, and the field is becoming increasingly complex, with several hundred new
64           Global control of tuberculosis has become increasingly complicated with the emergence of mu
65 egrity of P. yoelii plasmei2(-) liver stages became increasingly compromised late in development and
66 ses, the challenges of fragment assembly are becoming increasingly computational.
67                  Pediatric hospital care has become increasingly concentrated, and many children with
68      The ability of fishers to diversify has become increasingly constrained in the last few decades,
69                        Over time the HBM has become increasingly controversial, and recent studies cl
70 te matter microstructure across brain tracts becomes increasingly correlated in older age.
71  BRD2 depletion, expression of the two genes becomes increasingly correlated.
72    With the fast growing genomic data, it is becoming increasingly critical for biology researchers t
73                          Such integration is becoming increasingly critical with the rapid growth of
74 r genomic and comparative genomic context is becoming increasingly crucial to make full use of the da
75  the onset of subsequent depressive episodes becomes increasingly decoupled from external stressors.
76 survival and global gene expression programs become increasingly dependent on Clr4/SUV39H, the sole h
77                                        As we become increasingly dependent on electronic information-
78 re evolves, offspring in some taxa appear to become increasingly dependent on their parents.
79                Oncology clinical trials have become increasingly dependent upon image-based surrogate
80                 In C4 leaves this regulation becomes increasingly dependent on the chloroplast.
81       The cognitive function of older adults becomes increasingly dependent on these factors.
82  analysis by mass spectrometry (imaging) has become increasingly deployed in preclinical and clinical
83                                     Sedation became increasingly difficult, and in order to limit adm
84 nolone resistance in Salmonella enterica has become increasingly difficult due to evolving resistance
85 e treatment of S. marcescens infections will become increasingly difficult in the future.
86 sizes of imaging data sets grow, these tasks become increasingly difficult, especially when the image
87 ith precise size and shape control, yet this becomes increasingly difficult at sizes of approximately
88 red, however, stalling the rejection process becomes increasingly difficult, leading to graft failure
89 neral health, the maintenance of oral health becomes increasingly difficult.
90  and functionally important large species is becoming increasingly difficult.
91 that Fresno's land and water management have become increasingly disconnected in recent years, with t
92 rs changed over time, with Atx. ferrooxidans becoming increasingly displaced by the autotrophic iron-
93               Modular boundaries continue to become increasingly distinct with age, as surrounding ex
94 initially highly overlapping burst sequences become increasingly distinct.
95            Biophysical properties of neurons become increasingly diverse over development, but mechan
96 ne tension in the order of -10(-10) J/m that becomes increasingly dominant with increasing curvature
97 inally abundant but subsequently disappeared became increasingly dominated by tropical herbivores.
98 in is part of the unstructured region, which becomes increasingly dynamic towards the C-terminus.
99 e presence of dantrolene but that dantrolene becomes increasingly effective as cytoplasmic-free [Mg(2
100  the model predicts that cell-to-cell spread becomes increasingly effective as infection progresses a
101                   mRNAs with shorter 3' UTRs became increasingly enriched in RNPs from pachytene sper
102 ironment, their representations in our brain become increasingly enriched with our acquired "top-down
103 ur environment, their neural representations become increasingly enriched with our acquired knowledge
104 rly 40% of the world's population, and it is becoming increasingly entwined in daily life.
105                      In recent years, it has become increasingly evident that cholesterol-driven effe
106                   In the past decade, it has become increasingly evident that several important devel
107 f HPV vaccination in real-world settings has become increasingly evident, especially among girls vacc
108                As Gold suggested, and as has become increasingly evident, to better understand the su
109 ch signaling in pancreatic tumorigenesis has become increasingly evident; however, it remains unclear
110                                        It is becoming increasingly evident that "connector regions" a
111 ncer, ischemia and cardiovascular disease is becoming increasingly evident, the study of TRPM7 in mou
112 roteomic profiling to large cohorts has thus become increasingly feasible with emerging affinity meth
113 gineering technologies such as CRISPR, it is becoming increasingly feasible to apply these molecular
114 sex differences is human lifespan, which has become increasingly female-biased in recent centuries.
115         As malaria transmission declines, it becomes increasingly focal and prone to outbreaks.
116 e markedly as we age, and in many cases they become increasingly fragmented.
117 s provide no evidence that social sorting is becoming increasingly genetic in nature or that dysgenic
118                As winter progressed, monkeys became increasingly heterothermic and displayed lower 24
119 axa hybridize extensively, their genomes may become increasingly homogenized over time.
120 l influence and group polarization as people become increasingly immersed in social media networks.
121  became widespread, whilst their environment became increasingly impacted by fishing, climate change,
122          Identification of endotypes is also becoming increasingly imperative because targeted biothe
123 thesized that symbiont-symbiont interactions become increasingly important along a parasitism/mutuali
124              Overall, drug repurposing could become increasingly important as a way of advancing alle
125 a strong driver of global diversity and will become increasingly important as human influences drive
126 s and tissues, that is, humanized mice, have become increasingly important as small, preclinical anim
127 Such natural resilience of reef systems will become increasingly important as the frequency of distur
128 mpact on ecosystem services and is likely to become increasingly important as this phenomenon intensi
129 n-Hispanic white women and minorities should become increasingly important because of the projected g
130  duration, the combined impacts of them will become increasingly important drivers of physiological a
131              MicroRNA profiling methods have become increasingly important due to the rapid rise of m
132  and neck cancer survivors increases, it has become increasingly important for health care providers
133       Protected refuge areas could therefore become increasingly important for ongoing translocation
134  that can predict response to therapies will become increasingly important for personalised medicine
135                                     This has become increasingly important given the popularity of la
136                               Nanoionics has become increasingly important in devices and systems rel
137 -the-Winner model wherein temperate dynamics become increasingly important in ecosystems with high mi
138         Colloidal semiconductor nanocrystals become increasingly important in materials science and t
139 ng synergistically to kill cancer cells have become increasingly important in melanoma as an approach
140              Rare earth elements (REEs) have become increasingly important in modern day technologies
141 )Ga-labeled and (18)F-labeled PET agents has become increasingly important in recent years.
142 e clinical management of cancer patients has become increasingly important in recent years.
143  functional measures of the human brain, has become increasingly important in recent years.
144 linical hormone replacement (HR) will likely become increasingly important in the growing populations
145         Therefore, the targeting of PSMA has become increasingly important over the last decade.
146                             Social media has become increasingly important over the past decades and
147 equency of multiwell pads increases, it will become increasingly important to characterize the range
148 the neocortex are currently underway, it has become increasingly important to incorporate the cortico
149 y increases and interactions among symbionts become increasingly important to symbiont community asse
150   Results indicate that dissolution dynamics become increasingly important with increasing adsorption
151 mented over 100 years ago, tospoviruses have become increasingly important worldwide since the 1980s
152       This type of microecological study has become increasingly important, especially with the emerg
153 in an era in which health care outcomes have become increasingly important, these results are concern
154 c methods for feature learning like AMA will become increasingly important.
155 ntation, such as urologic malignancies, have become increasingly important.
156  one-dimensional limit, atomic-scale effects become increasingly important.
157 agents with strong immune system effects has become increasingly important.
158 quatic ecosystems in a changing climate will become increasingly important.
159 lity of UPF1 to undergo hyperphosphorylation becomes increasingly important for NMD when downstream f
160                       Whole grain teff flour becomes increasingly important in healthy food market, a
161  of phylogenetically closely related species becomes increasingly important in shaping moth assemblag
162 e cost of psoriasis therapies skyrockets, it becomes increasingly important to find biomarkers that p
163  medical applications is expanding; thus, it becomes increasingly important to improve and develop me
164                 As this population grows, it becomes increasingly important to understand the longer-
165 rogen-bonding interaction of (SO2)O...H(H2O) becomes increasingly important with the increase of drop
166 ort in the different compartments of kidneys becomes increasingly important.
167 ospital transfer of acute stroke patients is becoming increasingly important as regional stroke syste
168 d from immortalized mammalian cell lines are becoming increasingly important as therapies.
169                   Chemiresistive sensors are becoming increasingly important as they offer an inexpen
170 population dynamics of long-lived species is becoming increasingly important due to recent and future
171                         These new models are becoming increasingly important for a mechanistic unders
172 ification of patients with HIV and NAFLD are becoming increasingly important for accurately counselli
173 s to toxic lead-based primary explosives are becoming increasingly important for energetic materials.
174 tanding how to mitigate language barriers is becoming increasingly important for health care provider
175                          Water adsorption is becoming increasingly important for many applications in
176         Bio-based production of n-butanol is becoming increasingly important for sustainable chemical
177 n of genetic variants in the human genome is becoming increasingly important for understanding geneti
178     Flexible and stretchable electronics are becoming increasingly important in many emerging applica
179 drugs and biologically relevant molecules is becoming increasingly important in the pharmaceutical in
180 cs' (i.e. transcriptomics and proteomics) is becoming increasingly important to the understanding of
181 iversity continues to decline steeply, it is becoming increasingly important to understand diversity
182  Integrative analysis of multi-omics data is becoming increasingly important to unravel functional me
183            The detection of those targets is becoming increasingly important to yield the full functi
184 to measure plant stress in vivo responses is becoming increasingly important.
185 workshops in a way that facilitates reuse is becoming increasingly important.
186  disease pathogenesis and/or progression are becoming increasingly important.
187 te, research in automated text processing is becoming increasingly important.
188 ion between people from different nations is becoming increasingly important.
189 ic identification of DDIs from literature is becoming increasingly important.
190  from multiple sequence alignments (MSAs) is becoming increasingly important.
191 ugmentation of the renal microenvironment is becoming increasingly-important in renal MSC therapies.
192 d extensive dilution, but this strategy will become increasingly impractical.
193 abases to approximately 10 gigabases, errors become increasingly inevitable but their number remains
194 ical synthetic and biosynthetic studies will become increasingly interdependent.
195 In recent years evolutionary ecologists have become increasingly interested in the effects of reactiv
196              Coagulation factor XI (FXI) has become increasingly interesting for its role in pathogen
197 vironmental friendly, these systems are thus becoming increasingly interesting for the design of new
198 s two species diverge from one another, they become increasingly isolated by reproductive incompatibi
199 hile the low-energy ytterbium (Yb) 4f states become increasingly itinerant, acquiring additional spec
200                  As medical genomics studies become increasingly large and diverse, gaining insights
201 male brain development, and that this effect becomes increasingly likely with each male gestation, al
202 directly on soil water availability that may become increasingly limited as temperatures rise.
203 nce is on the rise and current therapies are becoming increasingly limited in both scope and efficacy
204 osystem succession, as a resource (nitrogen) became increasingly limiting.
205 tions of directional linear nanoantennas has become increasingly mature, angular control of nonlinear
206     In the presence of IL-15 inhibition, TEM became increasingly more sensitive to IL-7 stimulation i
207 itative traits and physiological markers has become increasingly more important, as this may lead us
208 tems and find a very rich phase diagram that becomes increasingly more complex as the number of inter
209    A less stable hairpin structure, however, becomes increasingly more stable in oligomers, where hyd
210 ing a tumor's detailed molecular profile has become increasingly necessary to deliver the standard of
211 ria to maintain quiescence and stemness, and becomes increasingly necessary with age to preserve the
212 the sea shore (i.e. downward QH), with Tw-Ta becoming increasingly negative with increasing Ta.
213 subtle contributions to stability as designs became increasingly optimized.
214  8-22 to show that white matter connectivity becomes increasingly optimized for a diverse range of pr
215  bond which suggests that the solvated water becomes increasingly ordered with time in the assembled
216 l-looking cells surrounding transformed foci became increasingly permissive for transformation with s
217 s of the cyanobacterium Microcystis sp. have become increasingly pervasive in the San Francisco Estua
218               In addition, genome editing is becoming increasingly plausible as a treatment modality
219            The consumption of probiotics has become increasingly popular as a means to try to improve
220 ent during winemaking and bottle storage has become increasingly popular due to its impact on the sen
221 n demand Diels-Alder (iEDDA) reactions, have become increasingly popular for live-cell imaging applic
222                 Solid-phase PCR (SP-PCR) has become increasingly popular for molecular diagnosis and
223 es in networks combining node attributes has become increasingly popular in recent years.
224 ears, texture analysis of medical images has become increasingly popular in studies investigating dia
225 the last two decades, flow technologies have become increasingly popular in the field of organic chem
226 derstanding of the immune system, but it has become increasingly popular to emphasize their shortcomi
227 es (GWAS) with "time to event" outcomes have become increasingly popular, predominantly in the contex
228 minimal or no chromatographic separation has become increasingly popular.
229 ehensive liquid chromatography (LC x LC) has become increasingly popular.
230 istic inference from real-time input data is becoming increasingly popular and may be one of the pote
231      Chronic beta-alanine supplementation is becoming increasingly popular for improving high-intensi
232  cell RNA sequencing (scRNAseq) technique is becoming increasingly popular for unbiased and high-reso
233 us-flow platforms for synthetic chemistry is becoming increasingly popular in research and industrial
234           Although mixed methods research is becoming increasingly popular in the area of coronary ar
235                                 Argan oil is becoming increasingly popular in the edible-oil market a
236   Messenger RNA as a therapeutic modality is becoming increasingly popular in the field of gene thera
237 tative methods within 1 program of study, is becoming increasingly popular to allow investigators to
238                            Meta-analyses are becoming increasingly popular, especially in the fields
239 acterization of proteins in the gas phase is becoming increasingly popular, highlighting the need for
240  whole-genome DNA accessibility measurements becoming increasingly popular, our work demonstrates how
241 ries RNA-seq experiments, in particular, are becoming increasingly popular, yet there are no methods
242 toms in bioactive substances with silicon is becoming increasingly popular.
243 effects of eCO2 and warming on C3 graminoids became increasingly positive and supra-additive over tim
244 ion and characterization of the disease have become increasingly precise through improved risk strati
245 ion under hot and dry conditions, which will become increasingly prevalent in the coming decades, hig
246 in-resistant Enterococcus (VRE) strains have become increasingly prevalent over the past decade.
247 sing metathesis is now not only possible but becoming increasingly prevalent in the literature.
248 nsively drug-resistant (XDR) tuberculosis is becoming increasingly prevalent worldwide, but little is
249   Purpose Type 2 diabetes mellitus (T2DM) is becoming increasingly prevalent worldwide.
250 diovascular disease and its risk factors are becoming increasingly prevalent.
251 t, since 2000, pharmaceutical companies have become increasingly profitable, with risk-adjusted retur
252 narios; the influence of excessive heat will become increasingly prominent by the late 21st century.
253 display a strong Fermi energy-dependence and become increasingly pronounced, while the normalized exc
254                                       It has becoming increasingly recognised because of improved and
255               One such complication that has become increasingly recognized is the development of car
256 ens is thus imperative as food allergies are becoming increasingly recognized as a major healthcare c
257  lipids and cellular water (soft matter) are becoming increasingly recognized as key determinants of
258 sphoinositide 5-phosphatase activity that is becoming increasingly recognized for its role in mediati
259                                        It is becoming increasingly recognized that our collective abi
260 tion in food and feedstock in particular has become increasingly relevant as these toxins, such as oc
261 ly, however, thermodynamic spin fluctuations become increasingly relevant in this few-spin limit.
262 ional use, certain public health issues have become increasingly relevant, including the effects of a
263 d formation and noncovalent interactions has become increasingly relevant.
264 within a complex mixture of DNA molecules is becoming increasingly relevant in many areas of clinical
265                   Computational methods have become increasingly reliable to understand materials ass
266 lly, at a time when almost every pathogen is becoming increasingly resistant to antimicrobials, we sh
267 me starting with multipotent stem cells that become increasingly restricted in their differentiation
268 ter diffusion through tissue, which normally becomes increasingly restricted and anisotropic in the b
269 ologic medications; as insurance formularies become increasingly restrictive and more patients are co
270 iophages exert selection for MDR bacteria to become increasingly sensitive to traditional antibiotics
271 ilicon single-photon avalanche detectors are becoming increasingly significant in research and in pra
272         Rather, the spatial tuning of inputs became increasingly similar across repeated traversals o
273 active state increased, but the active state became increasingly similar to the arrested state.
274 after the resolution of fibrosis, where they became increasingly similar to tissue-resident alveolar
275 aminant, 4-chloronitrobenzene (4-CINB), also became increasingly slower over time with virtually no 4
276 nteraction potentials, these two transitions become increasingly smeared together, so measuring a cle
277               Studies of the microbiome have become increasingly sophisticated, and multiple sequence
278           We determined that BCR repertoires become increasingly specialized over a span of decades,
279 or the treatment of bacterial infections has become increasingly strained due to increased rates of r
280 wet and dry conditions, we expect forests to become increasingly structurally mismatched to water ava
281                              Areas that have become increasingly suitable for breeding birds due to c
282 cross Africa and the Asia-Pacific region are becoming increasingly susceptible to the importation and
283  harnessing T-cell co-signaling pathways has become increasingly understood to have significant clini
284 hinery in recognizing faulty polypeptides is becoming increasingly understood.
285 e been expressed that operators/centers have become increasingly unfamiliar with transfemoral access.
286                         Global societies are becoming increasingly urban.
287 mechanisms influence population dynamics has become increasingly urgent in the face of rapidly changi
288 , achieving chip-based light non-reciprocity becomes increasingly urgent in signal processing and opt
289            Large relaxing retinectomies have become increasingly used in the repair of retinal detach
290 Multicomponent coupling reactions (MCRs) are becoming increasingly used in the synthesis of macromole
291 molecular knot topologies increases, it will become increasingly useful for chemists to adopt the kno
292 llular function, morphological profiling has become increasingly utilized to better understand functi
293                       Among SNP markers that become increasingly valuable in molecular breeding of cr
294 hroughput data using biological networks are becoming increasingly valuable.
295                   With combination therapies becoming increasingly vital to understanding and combatt
296 ss exposed to direct human stressors but are becoming increasingly vulnerable because of their develo
297 d the field, the use of nickel catalysis has become increasingly widespread because of its unique abi
298 e mortality and suggest that mortality could become increasingly widespread in the future.
299 e results imply that threshold responses may become increasingly widespread.
300 ution for sustainable food production and is becoming increasingly widespread.

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