ライフサイエンスコーパス: bedside

1 siderable potential for clinical use "at the bedside".

2 o translate disease treatments from bench to bedside.

3 ocusing on transitions between the bench and bedside.

4 for rapid point-of-care detection of PMPs at bedside.

5 ndidate therapeutics has moved from bench to bedside.

6 e used right by the critically ill patients' bedside.

7 peed with which these can move from bench to bedside.

8 mon, pragmatic approach by physicians at the bedside.

9 the laboratory into improved outcomes at the bedside.

10 allowed moving this biomarker from bench to bedside.

11 ) have been translated from the bench to the bedside.

12 eveloped in the laboratory are tested at the bedside.

13 oxygen enable estimation of CT shunt at the bedside.

14 rom the bench to their ultimate place at the bedside.

15 al risk" noted in outcomes trials and at the bedside.

16 in)/gain], was calculated from a grid at the bedside.

17 ul translation of laboratory research to the bedside.

18 he potential for real-time monitoring at the bedside.

19 evaluation of individual disease risk to the bedside.

20 ols for use in the field or at the patient's bedside.

21 process for inevitable limit setting at the bedside.

22 ased on information readily available at the bedside.

23 application of this technology from bench to bedside.

24 neuroendocrinology both at the bench and the bedside.

25 This direction is called bench-to-bedside.

26 or obstacles to moving from the bench to the bedside.

27 ransition of stem cell therapy from bench to bedside.

28 e unequivocally unconscious behaviour at the bedside.

29 ts use, as they evolve from the bench to the bedside.

30 engaged as partners with the ICU team at the bedside.

31 between theory and practice at the patient's bedside.

32 s may decrease time and effort from bench to bedside.

33 not worked itself to the clinical thrombosis bedside.

34 neous blinded clinical UAO assessment at the bedside.

35 ata consisted of observations of patients at bedside (170h in total); observations of the context of

36 Seventy-two percent of patients received bedside, 18% telephone, and 10% no IDS consultation.

37 in 94%, and 23 (6.6%) were leukoreduced (10 bedside, 2 prestorage, and 11 unknown).

38 amily members were absent from the patient's bedside (6.3 minutes [95% CI, 2.2-10.4] vs 11.7 minutes

39 nce, a novel measure readily attainable from bedside accelerometry.

40 e of time in a 24-hour period at the patient bedside after the intervention (8.3%; 95% CI 7.1%-9.8%)

41 lbourne Rapid Field, (MRF)) conducted at the bedside aided swift and appropriate management of the pa

42 ers are beginning to translate from bench to bedside along the paths of neuroprotection, gene replace

43 able tests that are simple to operate at the bedside and available 24 h a day, 7 days a week.

44 whole translational spectrum (from 'bench to bedside and back again') with recognition that both biol

45 f cerebral blood flow (CBFi) at the infant's bedside and compute an index of cerebral oxygen metaboli

46 , very few products have moved from bench to bedside and effective therapy remains lacking.

47 ally, the brain-injured subjects dissociated bedside and functional magnetic resonance imaging-based

48 vasive diagnostic instrumentation, with both bedside and intra-operative operation capability, is env

49 dentify non diabetic hypoglycaemic patients: bedside and laboratory blood glucose measurements; medic

50 d to the clinical research setting (bench to bedside) and then to clinical practice and eventually he

51 Through an iterative bench-to-bedside-and-back process, methods to efficiently add new

52 nd how our therapies work and to improve the bedside applicability of RCTs.

53 godendrocyte biology and neuroradiology with bedside applications may result in the possibility of cl

54 in the determination of tissue perfusion and bedside approaches to management of shock.

55 ers exist for either, which impedes bench-to-bedside approaches.

56 the development of treatments from bench to bedside are included.

57 tween DNIC and CPM, gauged between bench and bedside, are key for the development of analgesic therap

58 ightened awareness of this issue both at the bedside as well as in research, commitment to using stan

59 This study also reports that a simple bedside assessment for the presence and intensity of pai

60 In vivo bedside assessment of endothelium-dependent vasodilatati

61 ma Scale has provided a practical method for bedside assessment of impairment of conscious level, the

62 olism showed no significant association with bedside behavioral testing, except in a few cases when E

63 Recent researches for bedside biosensors are also discussed.

64 s shows potential for realising miniaturised bedside biosensors for clinical diagnostics exploiting M

65 ion in critical care-not just as part of the bedside, but as part of educational and management organ

66 ique is radiation free and applicable at the bedside, but lacks of spatial resolution compared to mor

67 measured physiologic variables using simple bedside calculations (functional hemodynamic monitoring)

68 commendations were made regarding the use of bedside cardiac ultrasound in pediatric patients ranging

69 veral class 1 recommendations for the use of bedside cardiac ultrasound, echocardiography, in the ICU

70 home-call with pediatric intensive care unit bedside care providers, patients, and their families is

71 the unit level where nurses provide 24-hour bedside care to patients.

72 red nurses need to assume responsibility for bedside care.

73 ss to clinical information and to facilitate bedside care.

74 ggest that PVP may be useful in the standard bedside clinical assessment of volume status in these pa

75 ediction algorithm may prove useful for both bedside clinical decision making and risk adjustment for

76 h the remote evaluation of fundus images and bedside clinical examination of infants at risk for ROP.

77 ical criteria that together constitute a new bedside clinical score termed quickSOFA (qSOFA): respira

78 At the bedside, clinical guidelines are fully applied in 24% of

79 ial is clinically important, will assist the bedside clinician in determining whether to apply the fi

80 gation of information can be used to aid the bedside clinician in this task: analysis of derived para

81 In the second phase, bedside clinicians were additionally assisted in guideli

82 behavioural evidence of consciousness at the bedside, clinicians may render an inaccurate prognosis,

83 resent a comprehensive pipeline for reliable bedside collection, sequencing, and analysis of the huma

84 Bedside confirmation of bundle checklists during physici

85 Patients with bedside consultation had lower mortality than patients w

86 Patients with bedside consultation more often had deep infection foci

87 Patients with bedside consultation were less often treated in an inten

88 ; CI, 95% 1.22-4.38; P = .01) as compared to bedside consultation.

89 ome a prototype for transition from bench to bedside, culminating in the development and clinical imp

90 gap exists in translating this knowledge to bedside decision making.

91 n time to admission was 2 h (IQR 1-3) with a bedside decision to admit, and 12 h otherwise (5-29).

92 uidelines have the potential to improve both bedside decision-making and health policy.

93 n sensors have potential applications in the bedside detection of heparin levels in human blood durin

94 Early bedside detection of intraventricular hemorrhage holds p

95 Early bedside detection of intraventricular hemorrhage is cruc

96 Bedside diagnosis of sarcopenia by ultrasound predicts a

97 ful biological surface functionalization for bedside diagnostic assays.

98 nstrates that fingerstick CRAG is a reliable bedside diagnostic test.

99 sts of a remote interventional cockpit and a bedside disposable cassette that enables the operator to

100 Bedside DOSI images of the tissue concentrations of deox

101 When comparing percutaneous bedside drainage to operating room burr hole evacuation,

102 he exposures were time from (1) admission to bedside dysphagia screen, and (2) admission to comprehen

103 We aimed to identify if delays in bedside dysphagia screening and comprehensive dysphagia

104 licity of use, availability at the patient's bedside, easy transportability, and relatively low cost

105 After a rapid bedside echocardiogram suggesting pulmonary embolus, thr

106 As bedside echocardiographic technology becomes more rapidl

107 Bedside echocardiography enabled confirmation of these r

108 Physicians can be taught bedside echocardiography in a time-effective manner with

109 se patients after cardiac arrest and enables bedside EEG interpretation of unexperienced readers.

110 ria can inform large-scale collaborative and bedside efforts to reduce inappropriate urinary catheter

111 Bedside electroencephalographic methods may corroborate

112 that the context, locale, and quality of the bedside evaluation are associated with neurobiological c

113 Recognizing the importance of the bedside evaluation as a healing ritual and a powerful di

114 Physicians often bypass the bedside evaluation for immediate testing and therefore e

115 Clinical bedside evaluation of auditory neglect is often difficul

116 This study highlights a simple bedside evaluation of itch and pain for suspicious skin

117 s approach may potentially be used for rapid bedside evaluation of patients with recent chest pain.

118 ease, physicians who forgo or circumvent the bedside evaluation risk the loss of an important ritual

119 Patients expect that some form of bedside evaluation will take place when they visit a phy

120 The bedside evaluation, consisting of the history and physic

121 Clinical bedside evaluations and right heart hemodynamic assessme

122 B or evaluated in emergency departments with bedside evaluations and/or routine laboratory tests, and

123 This study sought to provide bedside evidence of the potential link between cardiac m

124 quality care and to detect infants requiring bedside examination.

125 ion with patients who appear unresponsive to bedside examinations and cannot respond with existing ne

126 duce any communication responses in repeated bedside examinations.

127 am was created at our institution to provide bedside expertise in surgery, anesthesiology, respirator

128 are (POC), such as at primary clinics or the bedside, faces impediments because they may require high

129 enter study, we compared complications after bedside feeding tube placement using a blind technique i

130 tion on variable cutoffs of gait response to bedside fluid-drainage testing.

131 Recent studies suggest that bedside, formal infectious diseases consultation is more

132 tructed unipolar AF electrograms acquired at bedside from multiple windows (duration, 9+/-1 s) were s

133 elin or peptide YY plasma concentration with bedside functional assessment of gastric emptying.

134 Bedside handheld spectral-domain optical coherence tomog

135 ient participation in nursing shift-to-shift bedside handover can be enacted.

136 ed, we discovered that the patient's role in bedside handover involves contributing clinical informat

137 barrier to enacting patient participation in bedside handover; and involving patients in beside hando

138 (Informatics for Integrating Biology and the Bedside) has developed a widely internationally adopted

139 Telephone IDS consultation is inferior to bedside IDS consultation.

140 cal practice suggests that clinicians at the bedside implement measure to attenuate the risk of unint

141 e in detecting cerebral hypoperfusion at the bedside in patients with severe traumatic brain injury a

142 If deployed at the bedside in the clinical context, such network measuremen

143 rformance of stellate ganglion blocks at the bedside in the ICU is feasible for patients who are suff

144 al stellate ganglion blocks at the patient's bedside in the ICU.

145 idge the translational gap between bench and bedside in the near future.

146 ment programs, bringing teaching back to the bedside, increasing resident autonomy, utilizing near-pe

147 nd he was stabilized after cardioversion and bedside intubation.

148 At the bedside, investigators collected data from 625 patients

149 critical care extends from the bench to the bedside, involving multiple departments, specialties, an

150 Translation of novel therapies from bench to bedside is hampered by profound disparities between anim

151 ation from cellular and animal models to the bedside is hampered by significant differences between s

152 c studies, and their translation back to the bedside, is expected to eventually lead to improvements

153 d space fraction is easy to calculate at the bedside, it may be useful for risk stratification and se

154 In "Bench to Bedside", Jennifer Warner-Schmidt peruses recent finding

155 In 'Bench to Bedside', Joel R. Chamberlain and Jeffrey S. Chamberlain

156 In this article, we review the bench-to-bedside journey of natalizumab, along with the lessons l

157 ry mechanics in acute neurologic conditions, bedside judgment, interpretation of additional laborator

158 In 'Bench to Bedside,' Keval Chandarana and Rachel Batterham examine

159 In Bench to Bedside, Kornelia Polyak peruses studies that uncover sp

160 The use of bedside lung ultrasound and echocardiography disclosed l

161 Bedside lung ultrasound and echocardiography have shown

162 le surrogates' satisfaction with physicians' bedside manner was associated with lower odds of conflic

163 of surrogates' satisfaction with physicians' bedside manner were associated with lower odds of confli

164 ion, and include patient-reported stiffness, bedside manoeuvres to evaluate myotonia, muscle specific

165 urrogate's belief that their presence at the bedside may improve the prognosis; and the surrogate's o

166 burdens required to bring lactoferrin to the bedside may limit its availability.

167 ng the first postnatal days is possible from bedside measures of brain activity prior to ultrasound c

168 specific detection of microRNA panels on the bedside, medical point-of-care systems that measure thos

169 e translation of basic science research into bedside medicine.

170 We aimed to determine which bedside method would provide positive end-expiratory pre

171 positive end-expiratory pressure, we applied bedside methods based on lung mechanics (ExPress, stress

172 ar collapse and overdistension, but reliable bedside methods to quantify them are lacking.

173 Here, we describe a bedside microdialysis monitoring technique for optimizin

174 omated hematology analyzers, microscopy, and bedside microfluidic devices provide clinically feasible

175 prescription and modifiable practices at the bedside might enhance enteral protein delivery in the PI

176 -term stability and separate vials to enable bedside mixing of antigen and adjuvant.

177 through the bedside to bench and back to the bedside model.

178 Bedside monitor alarms alert nurses to life-threatening

179 Continuous electroencephalography as a bedside monitor of cerebral activity has been used in a

180 The lack of bedside monitoring devices for alpha-amylase detection h

181 ons of a novel imaging approach that enables bedside monitoring of amygdala activity using fMRI-inspi

182 Bedside monitoring offers the opportunity to improve out

183 Most respondents (>80%) identified bedside monitoring, clinical exam, and imaging to be use

184 nalyzes electrocardiogram data from existing bedside monitors for decreased HR variability and transi

185 QT data were extracted from the bedside monitors for offline analysis.

186 rocardiography waveform time series from the bedside monitors of 9,232 ICU admissions.

187 Board, monitoring data were downloaded from bedside monitors of postoperative patients.

188 science every day, the principles from which bedside neurology is derived have broader consequences-f

189 of new liposomal nanomedicines from bench to bedside, new cost-effective and scalable production meth

190 Bedside noncontact SD-OCT imaging was performed after ob

191 Clinical or bedside nurse predictors of stress have been studied mor

192 they were communicated to the point-of-care bedside nurse via telephone, page, or facsimile.

193 nell Assessment of Pediatric Delirium by the bedside nurse.

194 Bedside nurses also recorded the total time and number o

195 lgesia quality, but inconsistent adoption by bedside nurses limited its impact.

196 These patients' attending physicians and bedside nurses were also enrolled.

197 understood and thought to lack relevance to bedside nursing practice.

198 Bedside nursing staff administered dexmedetomidine (or p

199 A 6-F tapered TL PICC was placed by a bedside nursing-based team with backup from the Interven

200 We recorded 24 h EEG at the bedside of 18 patients diagnosed to be vigilant but unaw

201 and lung tissue harvest was performed at the bedsides of 40 patients who died in intensive care units

202 To view this Bench to Bedside, open or download the PDF.

203 and ocular surface disease were assessed on bedside ophthalmologic examination.

204 HIV or other health-threatening pathogens at bedside or in resource-limited settings.

205 pt in which the knowledge generated from the bedside or the population can also be translated to the

206 It can be administered at the bedside or using combination of low- and high-fidelity s

207 icroscopy has the potential to provide rapid bedside pathologic analysis, but clinical adoption has b

208 FCM) represents a first step toward a rapid "bedside pathology" in the Mohs surgery setting and in ot

209 ration with a dedicated ID team performing a bedside patient evaluation within 1 hour of ED arrival.

210 citly did not seek to include discussions of bedside patient-family engagement or shared decision-mak

211 The frequency of bedside percutaneous tracheostomies is increasing in int

212 Bedside physicians have to make most diagnostic and trea

213 rformed multivariate statistical analyses of bedside physiologic monitoring data to identify such ear

214 eclinical testing for FXS; however, bench-to-bedside plans for the clinic are severely limited due to

215 ous after acute changes in blood flow, (2) a bedside point-of-care assay (platelet function analyzer-

216 nd 50 term infants with adequate images from bedside portable, handheld spectral-domain optical coher

217 Bedside positive end-expiratory pressure selection metho

218 ventilator settings and is able to influence bedside practice at moderate costs.

219 and to promote its translation into clinical bedside practice for stroke management.

220 y because staff did not think it relevant to bedside practice.

221 We developed a bedside predictive score for enterococcal IE-Number of p

222 ardized inspiration is a simple, noninvasive bedside predictor of fluid responsiveness in nonintubate

223 atment options vary from medical therapy and bedside procedures to major operative techniques.

224 ngs, allowing near-real-time notification of bedside providers about potentially injurious ventilator

225 th by electronic tools and by empowerment of bedside providers to advance care when clinical criteria

226 The computer system alerted bedside providers via the text paging notification about

227 r patients suspected of bacterial pneumonia, bedside pulse oximetry and urinary antigen testing for S

228 difficulty of obtaining thrombolytics at the bedside rapidly enough to administer during a code, and

229 is typically used to refer both to "bench to bedside" research, in which preclinical research finding

230 rs of this new drug class provide a bench-to-bedside review on preclinical validation of IDO1 as a ca

231 ve deaths, there is also a need for a simple bedside risk index to predict 30-day all-cause mortality

232 multivariable results, a reliable and simple bedside risk prediction tool was developed.

233 No simplified bedside risk scores have been created to predict long-te

234 ussion of a patient's delirium status during bedside rounds and through documentation systems.

235 cumented, elements were verified by provider bedside rounds.

236 Bedside screening for dysphagia was performed within 3 h

237 , no new treatment has made it from bench to bedside since tissue plasminogen activator was introduce

238 , we discuss how the tried and true bench-to-bedside strategies resulted in some spectacular successe

239 Second, bedside studies showed a higher incidence in plasma and

240 ctors to AF pathogenesis from both bench and bedside studies.

241 lth and disease, exemplified by the bench-to-bedside success of Jak inhibitors ('jakinibs') and pathw

242 sive than care delivered without access to a bedside supervisor, but was associated with lower reside

243 ade by a speech-language pathologist using a bedside swallowing evaluation.

244 screening triggered confirmatory specialist bedside swallowing examinations and follow-up until hosp

245 Lung ultrasonography (LUS) is a bedside technique useful to diagnose neonatal respirator

246 Patients were grouped according to bedside, telephone, or no IDS consultation within the fi

247 c screening method is needed for in-field or bedside testing of AI virus to effectively implement qua

248 , neurologic examination, neuropsychological bedside testing, and socioemotional assessments.

249 Simple bedside tests and somatosensory-evoked potentials predic

250 optimization of cardiac output is a feasible bedside therapeutic option, which should be considered w

251 e group randomized to presence or absence at bedside throughout the brain death evaluation with a tra

252 knowledge translation, moving away from the bedside to a focus on health systems, whereas translatio

253 desirable to estimate the GFR (eGFR) at the bedside to assess AKI or renal recovery.

254 elated acute lung injury (TRALI) through the bedside to bench and back to the bedside model.

255 Reverse pharmacology, also called the "bedside to bench" approach, that deals with new uses for

256 In "Bedside to Bench", Eric Nestler discusses two trials of

257 In Bedside to Bench, Maria Kleppe and Ross L. Levine look a

258 In 'Bedside to Bench,' Rachel Larder and Stephen O'Rahilly p

259 nical practice and eventually health policy (bedside to community).

260 , no calibration, and can be repeated at the bedside to generate almost continuous analysis of left v

261 s are beginning to be translated back to the bedside to improve treatment.

262 hat clinicians could easily calculate at the bedside to predict the risk of death of acute respirator

263 eed in rapid testing of visual fields at the bedside to screen for post-operative complications, such

264 ve potential, as investigators move from the bedside to the bench and back again.

265 This bedside-to-bench concept has not been explicated in psyc

266 hase III trials were discouraging, requiring bedside-to-bench translation and functional reevaluation

267 ction.SIGNIFICANCE STATEMENT We have used a "bedside-to-bench" approach to investigate the functional

268 Zrs might constitute a useful bedside tool for monitoring lung mechanics and improving

269 he Intensive Care Unit was the most specific bedside tool for the assessment of delirium in criticall

270 sed here is a safe, efficient, and objective bedside tool to guide decannulation decisions.

271 EIT may be an interesting noninvasive bedside tool to provide real-time monitoring of the PEEP

272 over the years, involving both non-invasive bedside tools (clinical decision rules and D-dimer blood

273 icroemboli burden, assessed noninvasively by bedside transcranial Doppler ultrasonography, correlates

274 linical reality through the ongoing bench to bedside transition, research in this field must focus on

275 M) is a remarkable example of rapid bench-to-bedside translation in new drug development.

276 Successful bench-to-bedside translation of nanomedicine relies heavily on th

277 Challenges exist in bench-to-bedside translation, but they are not insurmountable.

278 epresents a promising candidate for bench-to-bedside translation.

279 rder that have been developed via a bench to bedside translational model.

280 An interdisciplinary, bench to bedside translational research approach is crucial for t

281 ade CAR(+) T cells is an example of bench-to-bedside translational science that has been accomplished

282 ultimately use our benchside data to improve bedside treatment.

283 itical bottlenecks in translational bench-to-bedside tumor biology research.

284 Percutaneous bedside twist-drill drainage is a relatively safe and ef

285 a on the safety and efficacy of percutaneous bedside twist-drill drainage, single or multiple operati

286 Bedside ultrasonography has the highest accuracy of all

287 hy, investigation of portal venous gas using bedside ultrasonography may help the clinician to identi

288 udies on clinical findings and 22 studies on bedside ultrasonography met inclusion criteria for data

289 search was conducted for studies evaluating bedside ultrasonography.

290 of intraperitoneal fluid or organ injury on bedside ultrasound assessment is more accurate than any

291 tracts describing the diagnostic accuracy of bedside ultrasound compared with chest radiography for c

292 ater reliability, and efficiency to complete bedside ultrasound confirmation of central venous cathet

293 and meta-analysis to examine the accuracy of bedside ultrasound for confirmation of central venous ca

294 Bedside ultrasound is faster than radiography at identif

295 ting right hemi-liver volume (RHLV) by using bedside ultrasound measurement of right (R) and left (L)

296 Bedside ultrasound reduced mean central venous catheter

297 central venous catheter malposition exists, bedside ultrasound will identify four out of every five

298 pidly move translation from the bench to the bedside, we believe that cooperative research efforts ha

299 erspective on CRT's evolution from "bench to bedside." We also comment on the task faced by electroph

300 This knowledge has translated to the bedside with implications for clinical practice and dire