ライフサイエンスコーパス: been limited by

1 Semisynthetic access has also been limited by the lack of chemical tools for scaffold modif

2 portant regulatory and functional insights, but have so far been limited by the confounding effects of differentiation an

3 Clinical use of human IL-10 (hIL-10) has been limited by anemia and thrombocytopenia following systemi

4 Accessibility of diagnostic testing for COVID-19 has been limited by intermittent shortages of supplies required f

5 However, its application has been limited by its short half-life (~13 h), which requires d

6 ity to explore the cell biology of thermophilic archaea has been limited by the technical challenges of imaging at high t

7 However, the use of fluorescence lifetime in this area has been limited by the lack of strategies that provide spatiotem

8 , their incorporation into standardized in vitro assays has been limited by their incompatibility with packaging or form

9 ibution of tubulin and microtubules to spindle assembly has been limited by the fact that physiologically relevant tubuli

10 to link hippocampal dynamics to memory-guided behaviors has been limited by experiments that lack the temporal resolution

11 at data-intensive tasks like deep neural networks, but has been limited by the inaccurate and unpredictable switching of

12 ur understanding of the safety and efficacy of cannabis has been limited by decades of worldwide illegality and continues

13 Labeling of biomolecules in live eukaryotic cells has been limited by low component stability and slow reaction rat

14 reactions, the broader goal of molecular ON/OFF control has been limited by the inability of existing systems to achieve

15 ene expression data, but application to epigenetic data has been limited by the computational cost, lack of scalable soft

16 gn principles to applications in optoelectronic devices has been limited by the fragility of the supramolecular structure

17 However, their efficacy has been limited by slow diffusion of molecules and often require

18 Control of the TB epidemic has been limited by lengthy drug regimens, antibiotic resistance,

19 ation of high-quality distal associations (trans-eQTLs) has been limited by a heavy multiple testing burden and the prone

20 Progress, however, has been limited by the need for reversibly responsive materials

21 t into electricity, yet their commercial implementation has been limited by their high cost to output power ratio.

22 However, the clinical application of NANPs has been limited by factors such as chemical instability, ineffic

23 bility to characterize, classify, and analyze phenotype has been limited by measurement deficits, computing limitations,

24 ever, comparability, particularly for these procedures, has been limited by a lack of definitional clarity and their over

25 dictions regarding water mobility, and further progress has been limited by a lack of direct observations.

26 ressor miRNAs may hold therapeutic promise but progress has been limited by several factors, including the lability and h

27 However, the functional characterization of these QTLs has been limited by the heterogeneous cellular composition of GTE

28 ic underpinnings of eusociality in these marine shrimps has been limited by the sparse genomic resources in this genus.

29 However, use of this technology has been limited by reliance on indirect indexing of single-guide

30 The utility of ICI therapy has been limited by immune-related adverse reactions (irAEs) affe

31 r access to modern immunotherapies for cancer treatment has been limited by socioeconomic factors and inadequate research

32 great promise as medical tools, clinical applications have been limited by certain characteristics of phage biology, wit

33 f Gram-positive bacteria, but its medical applications have been limited by its poor aqueous solubility.

34 ammonium (NH(4)(+)) have been previously reported, but have been limited by their reliance on the electrocatalytic reacti

35 organisms such as C. elegans or isolated single cells have been limited by poor sensitivity of existing techniques and d

36 However, innovations in model form have been limited by methodological challenges.

37 ering the progression of malignancies, immunotherapies have been limited by an immunosuppressive tumor microenvironment (

38 Previous observations of lightning have been limited by camera sensitivity, distance from Jupiter and

39 the effect of coffee consumption on glucose metabolism have been limited by the use of surrogate insulin sensitivity indi

40 r wave systems, the studies of diffusive metamaterials have been limited by their characteristic spatial inversion symmet

41 the disease and the population biology of the parasite have been limited by the molecular tools currently available.

42 egarding changes in seizure frequency during pregnancy have been limited by the lack of an appropriate nonpregnant compar

43 n control within a hospital setting, but prior reports have been limited by small data sets, poor data quality, or both.

44 rotection against HIV disease progression, but studies have been limited by the low prevalence of this allele in North Am

45 solid-state lighting, lasing, and display devices that have been limited by existing methods.

46 However, they have been limited by low solubility and poor stability of active m

47 mopoietic stem cell transplantation (HSCT) has historically been limited by infrequent marrow biopsies, which increase th

48 dlife mortality due to endemic infections have historically been limited by an inability to directly observe wildlife mor

49 pite its biomedical significance, studies on AspH have long been limited by a lack of assays for its isolated form.

50 ce in determining cardiac lineage diversification has often been limited by the unreliability of genetic tracers.