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1 te in which it is more active than it was to begin with.
2 efinition of what qualifies as perceptual to begin with.
3 methods requires a large number of cells to begin with.
7 red via homologous recombination (HR), which begins with 5' end resection, mediated by exonuclease co
10 ric clinical event sequences most frequently began with a Giardia-specific test, whereas adult sequen
29 ly dynamic pattern of de novo transcription, beginning with a broad domain of expression during nucle
32 career pathway has taken a circuitous route, beginning with a Ph.D. degree in electrical engineering
33 c verbal fluency (walking while naming words beginning with a single letter), and complex dual task s
35 hilis screening by high-volume laboratories, beginning with a treponemal test such as the chemilumine
37 nd handedness was observed when the sequence begins with a beta-hGly residue instead of a (S)-beta-Ca
38 elped us learn that the most preferred route begins with a bidentate chelate binding of deprotonated
40 facile multicomponent catalytic process that begins with a chemoselective, site-selective and diaster
47 g the challenges of a top-down approach that begins with a many-body system, the size of which can hi
49 mbers need not be identified initially-MISST begins with a minimal representative set of known struct
54 d a system that circumvents co-culturing and begins with a self-supporting cell that grows autonomous
55 that oral CMV infection in infants typically begins with a single virus that spreads inefficiently to
56 an assembly pathway for the HIV-1 core that begins with a small CA sheet that associates with the RN
58 ECDC algorithm, in which syphilis screening begins with a treponemal immunoassay that is followed by
59 ude that the most likely catalytic mechanism begins with abstraction of a hydrogen atom from C-4 (or
61 ection of stimulus movement across the skin, begins with activation of low-threshold mechanosensory n
67 each guideline, the decision-making process began with an assessment of overall cardiovascular risk.
68 of Escherichia coli DNA polymerase V (pol V) began with an attempt to identify the mutagenic DNA poly
70 ion of water as life's matrix must, however, begin with an acknowledgment that our understanding of i
74 ting antibiotics, and, with this in mind, we begin with an unusual question: how low can antibiotic d
75 R package designed to simulate RNA-seq data, beginning with an experimental design and ending with co
76 malignancy, is primarily diagnosed visually, beginning with an initial clinical screening and followe
78 ceiver Operating Characteristic (ROC) chart, beginning with an over-motivated state with many false p
82 ear-cell type (ccRCC), the most common type, begins with an intragenic mutation in the von Hippel-Lin
83 sensorimotor circuits that guide exploration begins with an understanding of the pattern of motor out
90 oneered in Neurospora where circadian output begins with binding of the core circadian transcription
91 mptoms appear between 5 and 10 years of age, beginning with blindness and seizures, followed by progr
93 activate synapses that had few receptors to begin with, but that additional remodeling events are re
96 C-labelling study suggests that the reaction begins with cleavage of the unstrained C-C bond, followe
97 e disease caused by Streptococcus pneumoniae begins with colonization of the upper respiratory tract.
100 ed urinary incontinence, treatment generally begins with conservative management emphasizing the most
102 me-lapse imaging reveal that closure of gaps begins with contractility-mediated whole-tissue deformat
104 ive in the United States and the Netherlands began with coronary CT angiography, continued with cardi
110 students and postdocs who shared in the fun) began with dinucleoside phosphates and slowly worked our
111 of lung function in susceptible individuals begins with disordered airway basal cell biology (i.e.,
112 amed within a developmental perspective that begins with disturbances in glutamate synaptic developme
113 vealed that pitch classes have rainbow hues, beginning with do-red, re-yellow, and so forth, ending w
114 eries of specialized endosomal compartments, beginning with early endosomes harboring Rab5 and its ef
115 catalytic hydrodefluorination approach which begins with easily accessible perfluoroarenes and select
116 =12 months' type-specific duration and could begin with either a prevalent or incident infection.
118 anscribed during normal human embryogenesis, beginning with embryonic genome activation at the eight-
119 chain functionalization (IEG+) strategy that begins with enantiopure epoxides and facilitates the eff
120 field of insect host-parasitoid interactions beginning with endocrine influences of the tobacco hornw
121 rovides my reflections on these studies that began with enzymology and the use of cultured mammalian
122 inning ~5 ka, did a second demographic phase begin, with evidence for exponential population growth i
124 smitted by the respiratory route and illness begins with fever, cough, coryza, and conjunctivitis fol
125 at endogenous daily rhythms in the fetal SCN begin with few noisy oscillators on E14.5, followed by w
126 and observing the according phenotype, which begins with forward-genetic methods represented by rando
128 iscuss pattern and process in domestication, beginning with general findings about early domesticatio
132 ontinuum, similar to the HIV care continuum, begins with HIV testing followed by linkage of HIV-uninf
133 ed as therapeutic vectors to manage disease, begins with identification of the cell surface receptors
134 The implementation of these interventions, beginning with immediate action on salt reduction and st
136 elopments in the surgical management of NEC, beginning with indications for surgery and following wit
137 ding a comprehensive overview of their uses, beginning with initial applications through to the prese
138 nalysis of endogenous protein complexes that begins with intact leaves and combines chromatographic s
139 ermined during the preceding cell cycle that begins with invasion by a single, asexually committed me
140 better understand these clinical disorders, beginning with iPSCs generated from a patient with PTSx
141 common cause of chronic liver disease, which begins with isolated steatosis and advances to nonalcoho
142 we trace the contentious history of the VOF, beginning with its original discovery in monkey by Werni
147 nd honor individual preferences near the EOL beginning with making conversations with providers and f
150 tified a time-dependent pathological cascade beginning with mitochondrial oxidant stress leading to o
151 egies are currently used, a stepped approach beginning with more simple care that is progressed if th
155 that force generated at the parasite surface begins with no preferential directionality but becomes d
156 recommend a stepwise approach to treatment, beginning with non-drug interventions and then moving to
161 ental data for a wide range of V1 phenomena, beginning with orientation selectivity but also includin
164 d the spread of CHIKV to the Americas is now beginning, with over 100,000 cases occurring in the Cari
165 decline in the ecological role for cod that began with overfishing in this ecosystem will likely be
168 developed a correlated imaging approach that begins with performing matrix-assisted laser desorption/
169 We envision a self-reinforcing mechanism beginning with phosphomimetic R9C-PLB oxidation and loss
170 pidly progressing chorioretinal disease that begins with photoreceptor degeneration and includes atte
175 wo major steps of Rev-RRE complex formation, beginning with rapid Rev binding to a pre-organized regi
177 ophisticated machine with purified proteins, beginning with regulated CMG assembly and activation.
178 r a stepped-care model in which patients may begin with relatively nonintensive treatment, with incre
180 romic repeats)-associated (Cas) protein Cas9 begin with RNA-guided DNA unwinding to form an RNA-DNA h
181 eophyte the components of a TEM-based study, beginning with sample preparation through imaging of the
183 iation of the Vgamma9Vdelta2 T cell response begins with sensing of pAg via the intracellular domain
185 the relevance of these organic photovoltaics beginning with some of the economic drivers for these te
186 We show that neurogenesis in sea star larvae begins with soxc-expressing multipotent progenitors.
189 to advance through a series of transitions, beginning with spore germination and culminating with es
190 hosphoproteome at seven developmental stages beginning with stage VI oocytes and ending with two-cell
191 proaches for comparing two protein sequences begin with strings of letters (amino acids) that represe
195 I focus mainly on simple systems and models, beginning with systems without density dependence, which
196 ponent signaling pathway on model membranes, beginning with T cell receptor (TCR) activation and endi
198 ssible role of sleep in memory consolidation began with the early studies of Jenkins and Dallenbach (
201 tion for addressing noncommunicable diseases began with the need to address the epidemic of tobacco-c
203 ication and Endgame Strategic Plan 2013-2018 began with the synchronized global replacement of trival
205 amely, that the deposit growth and formation begin with the deposition of insoluble HAP shells around
206 initial stage of spinogenesis is thought to begin with the emergence of actin-rich dendritic filopod
208 analysis reveals architectural changes that begin with the incorporation of silicon into the hematit
209 f the release of synaptic vesicles generally begin with the movement of vesicles from the cloud into
210 this process is traditionally considered to begin with the polymerization of the highly conserved tu
211 ts and the predictive takeoff ensure flights begin with the prey visually fixated and directly overhe
213 or the observed clamping effect of complexin beginning with the acceptor t-SNARE complex and the subs
214 photosynthesis through serial endosymbioses, beginning with the adoption of a red alga by cryptophyte
215 iosynthesis occurs through similar pathways (beginning with the amino acid L-tyrosine), and the pathw
216 nt developments within the pyroptosis field, beginning with the discovery of Gasdermin D (GSDMD) as a
217 zontal cells (HCs) and amacrine cells (ACs), beginning with the early stages of postmitotic developme
219 2018 calls for the phased withdrawal of OPV, beginning with the globally synchronized cessation of tO
220 his network as either a processing hierarchy beginning with the inferior occipital gyrus (occipital f
221 combination of complex biochemical processes beginning with the initial insult and lasting for days,
222 w focused on modern, FDA-approved hypnotics, beginning with the introduction of benzodiazepines, limi
223 w focused on modern, FDA-approved hypnotics, beginning with the introduction of benzodiazepines, limi
226 marking developmental genes for activation, beginning with the onset of zygotic gene expression.
227 gical literature on race and race relations, beginning with the seemingly simple question: What is ra
229 gin withdrawal of oral polio vaccines (OPV), beginning with the type 2 component (OPV2), through a gl
230 hased withdrawal of oral poliovirus vaccine, beginning with the type 2 component, and the introductio
231 or a phased withdrawal of oral polio vaccine beginning with the type 2 component, introduction of ina
232 reviously separate avenues of investigation, beginning with the unexpected discoveries that nucleosom
235 for the biogenesis of phosphatidic acid that begins with the acylation of sn-glycerol-3-phosphate by
237 ukaryotic cells, protein synthesis typically begins with the binding of eIF4F to the 7-methylguanylat
238 tamate stimulates local translation in axons begins with the binding of glutamate to the ionotropic A
239 nant"; thus, it seems reasonable that vision begins with the color of objects as they naively appear
240 presented model, each new calculation cycle begins with the correction of the components' concentrat
242 tion instead follows a two-step pathway that begins with the creation of disordered clusters of 10-20
246 acquired (1D/2D NMR and RDCs), the procedure begins with the determination of the molecular constitut
248 l photoconductivity, the degradation process begins with the disintegration of grains rather than nuc
249 nonical translation initiation in eukaryotes begins with the Eukaryotic Initiation Factor 4F (eIF4F)
254 Assembly of a hepatitis B virus (HBV) virion begins with the formation of an RNA-filled core composed
257 propose that NO2(-) reduction by nitrogenase begins with the generation of NO2H bound to a state in w
259 at collagen fiber degradation by myroicolsin begins with the hydrolysis of proteoglycans and telopept
260 o P1 virions follows a distinct pathway that begins with the incorporation of DarA and Hdf and conclu
264 cascade of protein-protein interactions that begins with the opening of the N-terminal domain of cTnC
269 nes controls cladofulvin biosynthesis, which begins with the production of atrochrysone carboxylic ac
270 In budding yeast, centromere establishment begins with the recognition of a specific DNA sequence b
271 We show that poly(A) binding by CsPABPN1 begins with the recognition of the RNA-binding sites RNP
276 ion (ie, what to do), the 2015 consensus has begun with the GRADE methodology to provide direction fo
278 cific genetic aberration, eligibility should begin with this subset, including patients with other ma
281 of the renin-angiotensin-aldosterone system, began with Tigerstedt's discovery of renin, followed by
283 long terminal repeat (LTR) retrotransposons, begins with transcription by RNA polymerase II followed
285 view evidence that precursor-tRNA processing begins with transcription termination at the oligo(T) te
288 igand-gated ion channels, their gating cycle begins with transitions from a ligand-free closed state
289 coupled structural and electronic transition begin with two alternative starting points: a Peierls MI
290 addition, we now show that transcripts that begin with two or three capped guanosines ((Cap)2G or (C
292 ound to the PIWI protein Aubergine typically begin with uridine (1U), while piRNAs bound to Argonaute
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