ライフサイエンスコーパス: behavioral

1 omal protein levels and rescues FTLD-related behavioral abnormalities and retinal degeneration withou

2 us (BDV) results in neuronal destruction and behavioral abnormalities with differential immune-mediat

3 rome (22q11DS) is associated with early-life behavioral abnormalities, affected individuals are also

4 s, reversal of characteristic phenotypic and behavioral abnormalities, and prevention of premature de

5 tion protein 1 (TET1), in depression-related behavioral abnormalities.

6 imed to reveal the mechanisms underlying the behavioral action of NPS, and present a chain of evidenc

7 cted to examine the molecular, cellular, and behavioral actions of GLYX-13 to further characterize th

8 Participants were offered behavioral activation and completed an average of 6 week

9 eased thigmotaxis, abnormal spectra of basic behavioral activities, impaired muscle grip strength, an

10 For example, the behavioral adaptation of specialist Drosophila species t

11 Here we investigated behavioral adaptation to social defeat in mice and uncov

12 versial, yet many theories suggest a role in behavioral adaptation, partly because a robust event-rel

13 ent or expression of psychostimulant-induced behavioral adaptations.

14 ncluding lack of recovery sleep and impaired behavioral adjustment to a novel task after sleep depriv

15 striatal D2R availability and from increased behavioral aggression seen in active smokers.

16 This single light source induced significant behavioral alterations in birds, even in good visibility

17 d sickness is associated with a large set of behavioral alterations; however, its motivational aspect

18 proaches, building from molecular targets to behavioral analyses and vice versa, respectively.

19 ohistochemical, biochemical, functional, and behavioral analyses were performed in nerves harvested f

20 analysis, calcium imaging, optogenetics and behavioral analyses, we uncovered a circuit specific for

21 The behavioral and anatomical deficits seen in fragile X syn

22 ous system (CNS) inflammation with long-term behavioral and cognitive alterations.

23 rate experiments followed by a comprehensive behavioral and cognitive analysis.

24 to whether CBD attenuates or exacerbates the behavioral and cognitive effects of THC.

25 dbrain dopamine neurons are crucial for many behavioral and cognitive functions.

26 ommensurate with PDE2A inhibition along with behavioral and electrophysiological reversal of the effe

27 We characterized behavioral and functional changes in inducible condition

28 tion in WM has been associated with multiple behavioral and health features including demographic cha

29 to collect data on their socio-demographic, behavioral and life style characteristics, and diagnosti

30 trocytes have impaired brain development and behavioral and motor defects.

31 Here we demonstrate both behavioral and neural correlates of looming bias without

32 l and amphetamine reward sensitivity at both behavioral and neural levels in humans.

33 Three weeks later, after behavioral and nigrostriatal dopaminergic deficits had d

34 ight into the molecular mechanisms mediating behavioral and phenotypic plasticity.

35 Many behavioral and psychological effects of socioeconomic st

36 onding to the complex variables that trigger behavioral and social change.

37 pt genomic function to contribute to complex behavioral and somatic phenotypes.

38 Adjustment for demographic, behavioral, and ectopic body fat measures did not explai

39 lly encoded goals relevant to psychological, behavioral, and health responses to deprivation.

40 In the behavioral assay, fish avoided an introduced plume of OS

41 the SCN were concomitantly assessed through behavioral assays and calcium imaging.

42 We use quantitative behavioral assays and linkage mapping to identify a gene

43 y-2-butanone (AMC) were selected for further behavioral assays due to their temporal correlation with

44 Behavioral assays tested for functional outcomes, postmo

45 e used anatomical, electrophysiological, and behavioral assays to determine their patterns of connect

46 e preliminary evidence from experimental and behavioral biomarkers, that blockade of the V1a receptor

47 activation of PZ(Vgat) neurons inhibited the behavioral, but not electrocortical, arousal response to

48 lescence is a time of significant neural and behavioral change with remarkable development in social,

49 neurons within a brain region contribute to behavioral changes across the course of acute and chroni

50 s due to their temporal correlation with the behavioral changes of IJs towards the infected hosts.

51 t with the psychological, physiological, and behavioral changes that occur when individuals are expos

52 ded (n = 121) weight loss program supporting behavioral changes to promote a 5% weight loss.

53 ed with neither signs of desensitization nor behavioral changes.

54 ) and whether exposure to it would result in behavioral changes.

55 ot in maternal age, parity, socioeconomic or behavioral characteristics contribute to racial/ethnic d

56 its associated human phenotypes, an in-depth behavioral characterization of the Chrna7 deficient mous

57 This dopamine profile is specific to behavioral choice, scalable with interval duration, and

58 ant in executive cognitive function can bias behavioral choices away from immediate rewards.

59 ne), psychological (feeling in control), and behavioral (competence, dominance, and warmth) responses

60 we show that individuals develop specialized behavioral competences, originating already in the early

61 ons, we show that the PVT is central to this behavioral competition.

62 dorsal midline thalamus, is integral to this behavioral competition.

63 (IGCs), but the physiological mechanisms and behavioral conditions driving this plasticity remain unc

64 ing cortical representations under different behavioral conditions.

65 iction; however, the neuronal mechanisms and behavioral consequences of NRG3-ErbB4 sensitivity to nic

66 tudy the neural mechanisms that underlie the behavioral consequences of transcranial alternating curr

67 alterations could contribute to deficits in behavioral control and decision-making in adults who abu

68 omponents of the genetic programs underlying behavioral control in other animals too.

69 ost body but not in the brain, implying that behavioral control of the animal body by this microbe oc

70 that other miRNAs might also be involved in behavioral control.

71 ancient system of complex morphological and behavioral convergence, with replicate beetle lineages f

72 ation of area 25 decreased the autonomic and behavioral correlates of negative emotion expectation, w

73 w that resetting, its neural marker, and the behavioral cost it entails, are specific to situations t

74 show that MW relates simultaneously to both behavioral costs but also benefits.

75 reduce sedentary behaviors; and the harms of behavioral counseling interventions.

76 and sociodemographic, physical, dietary, and behavioral covariates across the Asian subgroups.

77 ve longitudinal epigenetic, neuroimaging and behavioral data from 132 adolescents, we demonstrate tha

78 Behavioral data indicate that vision and social experien

79 e resulting model accounts well for puzzling behavioral data on human participants and makes predicti

80 Importantly, both behavioral defects and structural changes of L5 PNs are

81 n = 45) for changes in tau transgene-induced behavioral defects.

82 logical spine remodeling that contributes to behavioral deficits by altering synaptic connections, an

83 nerve conduction, which could contribute to behavioral deficits in AS, including motor dysfunction.

84 Behavioral deficits in integrating complex audiovisual s

85 ate to sex-specific adverse outcomes such as behavioral deficits is a possibility that merits further

86 C. elegans DDC gene, bas-1, ameliorated the behavioral deficits of tau transgenic worms, reduced pho

87 ted whether these neurons can compensate for behavioral deficits resulting from midbrain dopamine dys

88 d both wild-type and SERT knockout mice from behavioral despair induced by chronic stress.

89 this significantly influences cognitive and behavioral development in later life.

90 approach to both typical and atypical early behavioral development.

91 p establish the correct daily phasing of the behavioral, developmental, and molecular events needed f

92 with a reference diagnosis (ie, the highest behavioral diagnosis obtained after six evaluations) usi

93 down-modulation of OXTR could contribute to behavioral differences observed in PR animals.

94 altered expression in neurodegenerative and behavioral diseases and were associated with noncoding r

95 to the pathogenesis of neurodegenerative and behavioral diseases.

96 gical link between inner ear dysfunction and behavioral disorders and how sensory abnormalities can c

97 apeutic approach for treating stress-induced behavioral disorders, and that dynamics are a critical a

98 However, behavioral disruptions disappeared when lights were exti

99 g cognition, perception, action, and emotion behavioral domains, to determine the potential existence

100 understanding circuit mechanisms that drive behavioral dysfunction is of critical importance for qua

101 ion syndrome (22q11.2 DS) show cognitive and behavioral dysfunctions, developmental delays in childho

102 The Behavioral Economic Incentives to Improve Glycemic Contr

103 These behavioral effects appeared to be correlated with functi

104 more recent in vivo works have demonstrated behavioral effects consistent with an STDP mechanism; ho

105 d the electrophysiological, biochemical, and behavioral effects of 2-AG deficiency by deleting its pr

106 ng blood-induced revitalization reverses the behavioral effects of aging.

107 ortices during rest and follow-up neural and behavioral effects of cognitive dissonance.

108 agonists have been shown to reduce multiple behavioral effects of drugs of abuse through their actio

109 ficantly affect SR time, revealing pervasive behavioral effects of miRNA regulation in the early larv

110 better understanding of the pharmacology and behavioral effects of opioids that underlie both their t

111 individual differences in the cognitive and behavioral effects of ovarian steroids in women, and may

112 Behavioral effects of scopolamine were assessed in BDNF

113 ion of CCK neurons mimics the antidepressant behavioral effects of SSRIs, suggesting that these cells

114 More specifically, galanin counteracts the behavioral effects of the systemic administration of mu-

115 as measured by decline of body temperature, behavioral effects, serum IL-4, IgE, and anti-drug Ab le

116 ncanonical role for trkB in STN DBS-mediated behavioral effects.

117 other behavioral tasks, which show decreased behavioral efficiency in adulthood after AIE.

118 We used behavioral, electrophysiological, immunohistochemical, a

119 We apply this framework to re-examine the behavioral evidence from these published studies.

120 d by prominent rhythmic activity, and recent behavioral evidence suggests that this might be coupled

121 sis, reinforcement learning simulations, and behavioral experimentation, we show that the resolution

122 these questions, we carried out a series of behavioral experiments in sighted and congenitally blind

123 neuroimaging, psychophysics, and traditional behavioral experiments, and we also summarize the curren

124 able to explain the findings of the reported behavioral experiments.

125 d the perceptual biases revealed through the behavioral experiments.

126 ighborhood, psychosocial, socioeconomic, and behavioral factors in young adulthood with the observed

127 k interaction positively correlates with the behavioral false-positive rate of face choices.

128 (ASD) is a developmental disorder defined by behavioral features that emerge during the first years o

129 s to emerge during a reversal task requiring behavioral flexibility.

130 l forecasts have not historically supplanted behavioral forecasts.

131 ity that sculpts excitatory transmission and behavioral function.

132 , it is unclear how LC coordinates disparate behavioral functions.

133 ut not posterior parietal, cortex eliminated behavioral gains from rehabilitative training.

134 auditory critical periods displayed impaired behavioral gap detection thresholds (GDTs), but this def

135 Behavioral generalization also tends to increase over ti

136 importance of spouse characteristics for the behavioral health consequences of spousal loss.

137 y and outcomes of care between an integrated behavioral health home and usual care.

138 The behavioral-health and neuroimaging data sets showed sign

139 ly reduced but could also be correlated with behavioral hyperalgesia.

140 ene delivery experiments to test circuit and behavioral hypotheses using a variety of manipulations,

141 n of hippocampal place cell sequences during behavioral immobility and rest has been linked with both

142 s that produce tolerance and determining its behavioral impact have proven difficult.

143 his effect in each participant predicted the behavioral impact of reward on search performance in sub

144 excessive grooming, hyperanxiety and social behavioral impairments.

145 e underlying anatomy, but also has important behavioral implications.

146 tion templates correlated with participants' behavioral improvement when the expected feature was tas

147 of natural language use may provide a useful behavioral indicator of nonconsciously evaluated well-be

148 ed during the course of human evolution, but behavioral inference from the fossil record is hampered

149 and default mode networks is associated with behavioral inhibition at age 2.

150 ng via the indirect pathway, associated with behavioral inhibition.

151 s used to obtain translational molecular and behavioral insights.

152 Earlier access to intensive behavioral intervention (IBI) is associated with improve

153 ing skin cancer-related behaviors or testing behavioral intervention effects on cancer-relevant outco

154 behavior when young MSM were provided with a behavioral intervention in conjunction with open-label T

155 The harms of behavioral interventions can be bounded as small to none

156 er or refer them to comprehensive, intensive behavioral interventions to promote improvements in weig

157 vel insights about the mechanisms underlying behavioral laterality in humans.

158 xEs on the molecular, cellular, circuit, and behavioral level and link this interaction to altered ri

159 e response at an anatomical, functional, and behavioral level.

160 Restoration of the pupil light reflex, behavioral light avoidance, and the ability to perform a

161 ly within the brain mainly due to the strong behavioral manifestations of sleep.

162 Our data therefore suggest that behavioral markers exist in awake sleepwalkers, characte

163 e capacity, at the larval stage, for precise behavioral measurements, genetic manipulations, and reco

164 y data as input and generates predictions of behavioral measures in novel subjects, accounting for a

165 divergence in subjective, physiological, and behavioral measures of conditioned fear.

166 ilize biochemical, electrophysiological, and behavioral measures to demonstrate that metabotropic glu

167 ent study, event-related potential (ERP) and behavioral measures were used to investigate the time co

168 , 18-59 years of age) completed a battery of behavioral measures, psychiatric assessment, and resting

169 ively guide dynamic decision making is a new behavioral mechanism by which MA rigidly biases choice b

170 Behavioral Model of Health Services Use and Behavioral Model for Vulnerable Populations.

171 conceptually grouped according to Andersen's Behavioral Model of Health Services Use and Behavioral M

172 se pathology; but may not be as effective as behavioral modifications at preventing the adverse metab

173 This work proposes a function for a behavioral modulation of visual processing and illustrat

174 Overall, post cues produced all of the behavioral modulations observed as a result of pre cues.

175 ct correlated positively with functional and behavioral modulations.

176 te a neural network that integrates distinct behavioral modules and suggest that central amygdala neu

177 Here, we employed a combination of behavioral, molecular and computational techniques to te

178 also implies a major potential confound for behavioral neuroscience experiments, at least in adult r

179 en structural connections and functional and behavioral outcomes is an essential but under-explored t

180 rnal-infant interactions yield metabolic and behavioral outcomes often differing by sex.

181 Key behavioral outcomes, including susceptibility, were repl

182 age sensory signal processing and subsequent behavioral outcomes.

183 -adolescents, by potentially altering reward behavioral outcomes.SIGNIFICANCE STATEMENT The present s

184 ugh multiple mechanisms to generate a common behavioral output, and that Lef1 regulates circuit devel

185 Hemodynamic, physiological, and behavioral parameters were compared between sated and ab

186 This behavioral pattern quickly changes upon exposure to diff

187 , but scallops showed significant changes in behavioral patterns during exposure, through a reduction

188 MPH administration improved behavioral performance and increased sustained inhibitor

189 Behavioral performance correlated with hand-region DTI m

190 n the MD system were accompanied by impaired behavioral performance.

191 correct responses, indicating more efficient behavioral performance.

192 ween brain FCD and individual differences in behavioral performance.

193 old age as well as individual differences in behavioral performance.

194 al of 1281 identified records) show that the behavioral phenotype of the ClockDelta19 mouse is charac

195 been implicated in the development of these behavioral phenotypes and facilitates extinction learnin

196 ce, a model that reproduces most of the core behavioral phenotypes of ASD, to test the effects of sys

197 The mice showed robust behavioral phenotypes reminiscent of aspects of human ma

198 GABA-B agonists have improved both brain and behavioral phenotypes, including social behavior.

199 tokines and exhibited significantly worsened behavioral phenotypes.

200 PARs in governing bidirectional synaptic and behavioral plasticity in the CNS.

201 Animals adjust their behavioral priorities according to momentary needs and p

202 justed associations of mode of delivery with behavioral problems assessed from parent-reported Rutter

203 ng for confounds) previously associated with behavioral processes, neurological disease, psychologica

204 ablishing complex and adaptive cognitive and behavioral processing.

205 es may ultimately contribute to their unique behavioral profiles and potential for development as coc

206 ics in the context of neurophysiological and behavioral recordings.

207 Behavioral recovery was significantly better in multipar

208 robust axon regeneration of DRG neurons and behavioral recovery.

209 ysiological basis of motor rhythms and their behavioral relevance and offer the possibility of develo

210 0 highly conserved proteins that control the behavioral repertoire, and mutations disrupting their fu

211 ther than an animal's more complete, natural behavioral repertoire.

212 r decision-making accuracy and expands their behavioral repertoire.

213 execution of the motor act associated with a behavioral report of the perceptual decision.

214 sual discrimination task with reaches as the behavioral report.

215 cally hard-wired neural mechanisms enforcing behavioral reproductive isolation include the interpreta

216 Despite their apparent behavioral rescue, synapse formation in these fish was s

217 However, gaps exist in behavioral research addressing all points of the skin ca

218 tions classify virtually all human brain and behavioral research as clinical trials.

219 However, recent theoretical, cognitive and behavioral research suggests that different strategies a

220 Behavioral resilience in mosquitoes poses a significant

221 pha'3 compartment plays a causal role in the behavioral response to novel and familiar stimuli as a c

222 Participants' behavioral responses (i.e., satisfaction ratings) were m

223 HFD also increased behavioral responses and paw swelling to paw injection o

224 These cellular and behavioral responses depended on the TRPA1 channel, whos

225 lliseconds, but the corresponding sub-second behavioral responses have not been adequately explored i

226 processing at the circuit level or abnormal behavioral responses in ASD mouse models, especially dur

227 alamic response and expression of compulsive behavioral responses involving meal anticipation and con

228 Impaired inhibition of fear or behavioral responses is thought to be central to PTSD sy

229 We find that behavioral responses made immediately after viewing a st

230 tress elicits neuroendocrine, autonomic, and behavioral responses that mitigate homeostatic imbalance

231 ordination of neuroendocrine, autonomic, and behavioral responses to acute and chronic stress.

232 quirement for PV+ interneurons of the NAc in behavioral responses to AMPH, and they raise the possibi

233 Importantly, loss of appetitive behavioral responses to fatty acids in IR25a and IR76b m

234 tic resonance imaging; and investigated main behavioral responses to opiates, including motivation to

235 ly obtainable with other techniques, such as behavioral responses to pharmacological manipulations an

236 ate defensive responses toward more adaptive behavioral responses to threatening stimuli.

237 ulation (TMS) with computational modeling of behavioral responses.

238 ulted in altered neurologic and/or locomotor behavioral responses.

239 BDNF release in driving scopolamine-induced behavioral responses.

240 Behavioral results and computational modeling confirmed

241 , modeled the function, and discovered a new behavioral role for a genetically defined population of

242 However, the behavioral role of M2 remains mysterious.

243 way for rigorous in situ measurements of the behavioral rules that underlie ecological rates in other

244 ts of marker specificity with an independent behavioral sample (n = 200), the empathic care marker wa

245 enetic risk and resilience in the social and behavioral sciences.

246 oncologists, molecular epidemiologists, and behavioral scientists to eliminate breast cancer dispari

247 There was no decrement in behavioral scores in control C57Bl6 treated with BPN1477

248 n to sensory regions, driving perceptual and behavioral selection.

249 tic spine formation and for cocaine-mediated behavioral sensitization.

250 A central model that describes how behavioral sequences are produced features a neural arch

251 blished laboratory model aimed at evaluating behavioral shifts in the salience of cocaine now vs mone

252 jection of ProTx II significantly attenuated behavioral signs of CIPN.

253 The physical and behavioral similarities between electrolocation and othe

254 id conditions, types of trauma exposure, and behavioral sources of inflammation).

255 Here, we show that the behavioral state alters the baseline activity levels and

256 feedback, consistent with observations that behavioral state influences reticular activity.

257 When foraging, food availability controls behavioral state switching between active (roaming) and

258 signaling pathways to control food-regulated behavioral state switching.

259 sed ripples and replays in CA1 regardless of behavioral state.

260 tions that mediate these acute risk aversive behavioral states via the LC-NE system remain unresolved

261 ress repertoire complexity in the context of behavioral states.

262 nformation with the theta wave regardless of behavioral states.

263 ibute to reproductive isolation and survival behavioral strategies.

264 reased calling rates in groups, displaying a behavioral strategy resembling the back-off algorithms u

265 SIGNIFICANCE STATEMENT: Previous behavioral studies have demonstrated that control states

266 is topic include the following: longitudinal behavioral studies of children to test associations betw

267 Behavioral studies suggest that vestibular signals play

268 d not engage the prefrontal cortex or elicit behavioral switch costs.

269 acy endpoint was the change from baseline in behavioral symptoms using the Anxiety Depression and Moo

270 of these risk-taking behaviors constituted a behavioral syndrome that significantly differed between

271 Using a novel behavioral task, we demonstrate that head-fixed mice can

272 onsistent with previous reports, using other behavioral tasks, which show decreased behavioral effici

273 g, but this has mostly been tested in simple behavioral tasks.

274 e PVT is essential for balancing conflicting behavioral tendencies toward danger and reward, enabling

275 covered shorter distance in a light and dark behavioral test compared to the controls.

276 Behavioral testing (handling and open field), continuous

277 We then performed repeat behavioral testing to identify which brain areas show ce

278 To assess the hypothesis, behavioral tests including chow and high-fat diet intake

279 mum caused little Wallerian degeneration and behavioral tests showed no significant long-term adverse

280 Finally, behavioral tests showed that the olfactory-specific Ric-

281 optical imaging and somatosensory and motor behavioral tests to characterize the consequences of bif

282 Behavioral tests were conducted to assess exploratory ac

283 stinct neuropharmacological effects in mouse behavioral tests.

284 Propranolol may be a useful adjunct to behavioral therapeutic interventions in recently traumat

285 and index of symptom change during cognitive-behavioral therapy (CBT) or selective serotonin reuptake

286 Cognitive behavioral therapy reduced primary anxiety symptoms more

287 g behavior, allowing us to perform long-term behavioral tracking.

288 nts by testing the hypothesis that extensive behavioral training alters the neural mechanisms that su

289 We investigated whether behavioral traits are pulled in different directions by

290 erived from this novel task and quantitative behavioral traits associated with the autism phenotype.

291 The genetic architecture of behavioral traits in dogs is of great interest to owners

292 avoidance learning, which may model certain behavioral traits resulting from traumatic experiences i

293 We also find that behavioral trajectories of worms subject to oxidative st

294 de DAF-7 each have stage-specific effects on behavioral trajectories, implying the existence of a mod

295 or many addicts is contingency management, a behavioral treatment that uses alternative non-drug rewa

296 erences by high-resolution tracking of known behavioral types in free-swimming stickleback (Gasterost

297 decision alternatives and strongly predicts behavioral value biases in decisions made approximately

298 ns induced prolonged cortical activation and behavioral wakefulness, whereas inhibition reduced wakef

299 We conducted the first randomized trial of behavioral weight loss for HIV-infected patients (n = 40

300 it comes to the brain-behavior relationship: behavioral work provides understanding, whereas neural i