ライフサイエンスコーパス: bell shape

1 oss the pure ESM membrane but with a steeper bell shape.

2 rrent-voltage (I-V) relationship for ICa was bell shaped.

3 se curve of GRP-stimulated DNA synthesis was bell shaped.

4 3-O-[(R)-3-hydroxymyristoyl]-GlcNAc are both bell-shaped.

5 d probability of having African ancestry was bell-shaped.

6 The V/K(ne) pH profile is bell-shaped.

7 permine, the k(cat)/K(amine)-pH profiles are bell-shaped.

8 second-order rate constants of inhibition is bell-shaped.

9 tes it at low concentrations, resulting in a bell-shaped activation profile.

10 HIV RNase H with Mn2+ or Co2+ ions generated bell-shaped activity dose-response curves.

11 c-Jun exhibits a bell-shaped activity on androgen receptor-mediated trans

12 H253A, K227A, H253A/K227A, and D234N remain bell-shaped, although their significantly lower activiti

13 or p-wave scattering with its tell-tale dumb-bell shape and no 90 degrees yield.

14 Starch granules showed round and bell shape and some irregular cuts on their surface with

15 ociation constant (k(lim)/K(d)) versus pH is bell-shaped and characterized by two macroscopic pK(a) v

16 tion of free enzyme with free cytochrome) is bell-shaped and closely resembles that of kox/Kd(cyt c),

17 he matrix metalloproteinase (MMP) family are bell-shaped and exhibit neutral pH optima.

18 (cat)/K(m) for URI from Escherichia coli are bell-shaped and indicate that one group must be unproton

19 ting with the l(o) phase, the OTP profile is bell-shaped and lies above that in the pure ESM membrane

20 ce of the fast central release component was bell-shaped and similar to that of I(Ca) in both cell gr

21 The pH profile of H224Q sHS is bell-shaped and similar to those reported for other MMPs

22 voltage dependence of the Ca2+ transient was bell-shaped and the maximum was centered at approximatel

23 r, binding data deviate from a stereotypical bell shape, and more binding occurs than expected at alk

24 nd the two components of central release was bell shaped, and the magnitude of each release component

25 citive component as a function of voltage is bell-shaped, and decreases with frequency.

26 Plots of activity versus log [metal ion] are bell-shaped, and the inhibitory phases of the profiles h

27 al evolution of Ca(2+) spark frequencies was bell-shaped, and the maximal spark frequency was reached

28 the data show that the size distribution is bell-shaped, and there is an approximately 40-A differen

29 en to separate the approximately symmetrical bell-shaped areas (negatives) from the skewed tails (pos

30 oM) concentration-response curve for LTP was bell shaped as no enhancement was seen with 30 microM se

31 s for the Y82F enzyme-catalysed reaction was bell-shaped as for the wild-type protein.

32 r PAD in response to 0.1-100 microM 5-HT was bell-shaped but in the capsaicin pre-treated group, a no

33 mutations shifted the peak of the InsP(3)R1 bell-shaped Ca(2+) dependence from 0.2 micro M to 1.5 mi

34 In [3H]ryanodine binding measurements, bell-shaped Ca2+ activation/inactivation curves were obt

35 all three mammalian InsP3R isoforms display bell-shaped Ca2+ dependence in physiological range of Ca

36 y InsP3 without shifting the peak of InsP3R1 bell-shaped Ca2+ dependence.

37 The bell-shaped Ca2+-dependence curve of type I InsP3R is id

38 Ca2+ for all three InsP3R1 isoforms; 3) the bell-shaped Ca2+-dependence is wider for the InsP3R1-SII

39 pS) than the InsP3R1-SII(+) (81 pS); 2) the bell-shaped Ca2+-dependence peaks at 200-300 nM Ca2+ for

40 Bell-shaped cell spreading curves encompassing all subst

41 do not respond to RANTES with the classical bell-shaped chemotactic response curve, suggesting that

42 lution structure reveals an asymmetric, dumb-bell-shaped complex with 4-fold symmetry, a length of 14

43 The structure of dsRBD exhibits a dumb-bell shape comprising two tandem linked dsRNA-binding mo

44 With these constructs, the bell-shaped concentration dependence of leukocyte migrat

45 tokines like IL-8, and also has the familiar bell-shaped concentration dependence seen for CXC cytoki

46 st-noncompetitive antagonist hybrids produce bell-shaped concentration-response curves, whereas the a

47 response at higher concentrations, producing bell-shaped concentration-response curves.

48 ar Ca2+ and [3H]noradrenaline release with a bell-shaped concentration-response profile; maximum enha

49 The k(cat)/K(m) value for the peptide is bell-shaped, consistent with a requirement that the nitr

50 e-channel Ca2+ current (iCa) rather than the bell-shaped current-voltage (I-V) relation of macroscopi

51 onditions, Hg(II) bioavailability followed a bell shaped curve as DOM concentrations increased, both

52 a coli and Aquifex aeolicus LpxC displayed a bell-shaped curve (EcLpxC yields apparent pKa values of

53 We calculate the bell-shaped curve and show that, if materials can be eng

54 te constant versus pH profiles were fit to a bell-shaped curve for all adducts.

55 PtNHase was found to exhibit a bell-shaped curve for plots of relative activity versus

56 CtNHase was found to exhibit a bell-shaped curve for plots of relative activity vs pH o

57 The acidic pK(a) in the bell-shaped curve is due to the phenolic hydroxyl of Tyr

58 We show that a bell-shaped curve of cleavage activation is obtained as

59 Analysis at different pH values produced a bell-shaped curve of the WT enzyme, but D387G exhibited

60 esulted in mitotic arrest with a symmetrical bell-shaped curve over time.

61 -direction the dependence of kcat of pH is a bell-shaped curve that is described by pKaS of 6.4 and 1

62 distinguishable from the second phase of the bell-shaped curve that was obtained in the absence of ha

63 nectin concentrations tested and shifted the bell-shaped curve upwards.

64 In general, a bell-shaped curve was obtained for each of the MT-MMPs i

65 ergent concentration dependent, exhibiting a bell-shaped curve with its maximum activity near the cri

66 nase (MMP) catalysis is described by a broad bell-shaped curve, indicating the involvement of two uns

67 ct of heparin with all FXa derivatives was a bell-shaped curve, which disappeared if the ionic streng

68 The ANG pH-rate profile is a classic bell-shaped curve, with pK(1) = 5.0 and pK(2) = 7.0.

69 of log k(cat)/K(m) versus pH is a distorted bell-shaped curve, with slopes of +1 on the acid side an

70 at n = 3, and then declines: the result is a bell-shaped curve.

71 ing channels as a function of log10(Ca) is a bell-shaped curve.

72 was dosage dependent on the inducer, with a bell-shaped curve.

73 cose with a response profile that followed a bell-shaped curve.

74 The 'bell-shaped' curve relating cytosolic Ca(2+) concentrati

75 the trough concentrations obtained from the bell-shaped curves are comparable to normal plasma level

76 Apparently corresponding bell-shaped curves displaying the pro-oxidant effect of

77 th log k cat/ K m and log k cat conformed to bell-shaped curves for which an inverse solvent kinetic

78 he mutants as a function of pH display broad bell-shaped curves that are similar to the wild-type enz

79 the pH-dependence of V(max) and V/K describe bell-shaped curves, consistent with the hypothesis that

80 trations (10(-1) to 10(5) units/ml) produced bell-shaped curves, demonstrating that inhibition occurs

81 Instead of the expected narrow bell-shaped cytoplasmic free Ca2+ concentration ([Ca2+]i

82 we show that in contrast to IL-8, where the bell-shaped dependence arises from the effects of CXCR1/

83 rmediate at 505 nm is affected by pH, with a bell-shaped dependence for the forward rate constant, k(

84 Unlike interfering with the bell-shaped dependence of InsP(3)Rs to [Ca(2+)](i), CT9

85 wever, these synthetic lipids give rise to a bell-shaped dependence of membrane permeability on [Chol

86 two p K a values previously observed by the bell-shaped dependence of the LpxC-catalyzed reaction.

87 arcus theory of electron transfer predicts a bell-shaped dependence of the reaction rate on the react

88 ude of the caged ADP tension transient had a bell-shaped dependence on Ca(2+), reaching a maximum at

89 open probabilities for PC-2 and S812A show a bell-shaped dependence on cytoplasmic Ca(2+) but there i

90 centration, whereas the type I isoform has a bell-shaped dependence on cytoplasmic Ca2+.

91 e constants did not exhibit a characteristic bell-shaped dependence on heparin concentration.

92 currents, the membrane capacitance showed a bell-shaped dependence on membrane potential with a peak

93 ve previously shown that MshB activity has a bell-shaped dependence on pH with pK(a) values of approx

94 d to Zn(2+)-LpxC; both metalloenzymes have a bell-shaped dependence on pH with similar pK(a) values,

95 In particular, movement amplitude showed a bell-shaped dependence on stimulus frequency, with a pea

96 tion kinetics, and the noise has a predicted bell-shaped dependence on the activation states of the e

97 er, the rate of charge recombination shows a bell-shaped dependence on the inverse temperature, first

98 2+)](i) transient amplitudes and I(Ca) had a bell-shaped dependence on V(m), but [Ca(2+)](i) reached

99 reasonably well the experimentally observed bell-shaped dependencies of bovine serum albumin or gela

100 y blocked by cobalt, and exhibited a similar bell-shaped dependency on voltage with a peak response a

101 The pH dependence of the activity was bell-shaped, depending on the ionization state of two gr

102 The pH-activity profile was bell-shaped, depending on the ionization state of two gr

103 The pH profile was bell-shaped, depending on the ionization state of two io

104 ially after lavage and were sigmoidal with a bell-shaped derivative function.

105 eric species built from the association of a bell-shaped dimer, a process we characterized by electro

106 ind the Dorsal gradient maintains a constant bell-shaped distribution during embryogenesis.

107 ns exhibit a 60% incidence of diabetes and a bell-shaped distribution of insulin levels as related to

108 f subjects to clopidogrel followed a normal, bell-shaped distribution, with a mean and standard devia

109 doses of 0.1, 0.3 and 1.0 mg/kg, produced a bell-shaped dose response effect on DA efflux in the mPF

110 fic IgE and challenged with Pen a 1 showed a bell-shaped dose response for secretion, with optimal Pe

111 The ORL-1 antagonist also eliminated the bell-shaped dose-response curve for buprenorphine-induce

112 Thus, Cas exhibits an unusual bell-shaped dose-response curve in response to EGF stimu

113 and high concentrations, reminiscent of the bell-shaped dose-response curve obtained for TBS-induced

114 ) versus 5-HT(7) receptors, may underlie the bell-shaped dose-response curve via a mechanism of 'cros

115 he presence of tetrodotoxin, NMDA produced a bell-shaped dose-response curve with stimulation of phos

116 ed the GTPase activity following an inverted bell-shaped dose-response curve, whereas when EF-2 and r

117 uced pMF was dose dependent, but exhibited a bell-shaped dose-response curve.

118 ions in both pMHC affinity and dose produced bell-shaped dose-response curves and different optimal p

119 In addition, two narrow bell-shaped dose-response curves were identified with ma

120 rease in its inhibitory effect, resulting in bell-shaped dose-response curves.

121 tly increased cell proliferation albeit with bell-shaped dose-response kinetics.

122 mber of these analogues were found to have a bell-shaped dose-response profile in the alpha1 beta2 ga

123 tment increased the PKCalpha activity with a bell-shaped dose-response relationship peaking at 10 nM,

124 d each affected the rotational behavior in a bell-shaped dose-response relationship producing increas

125 s 3-5 each affected rotational behavior in a bell-shaped dose-response relationship producing maximal

126 ents but to a lesser extent, indicative of a bell-shaped dose-response relationship.

127 PKCalpha-PLC-phospholipase D (PLD)-mTOR in a bell-shaped, dose-dependent manner requiring the Ca2+ se

128 Many tektites have elongated or 'dumb-bell' shapes due to their rotation mid-flight before sol

129 with the 5' flanking region of Tac1 showed a bell-shaped effect of SDF-1alpha on luciferase activity

130 nct binding sites for halides comes from the bell-shaped effects observed when the second-order rate

131 Extreme values of Psi0 lead to asymmetric, bell-shaped extension-rotation profiles with sharp maxim

132 ed by circular dichroism exhibit reversible, bell-shaped folding and unfolding transitions, implying

133 al V-delta L relationship was converted to a bell shape following the magnitude of ICa when internal

134 rofiles for both k(cat) and k(cat)/K(m) were bell-shaped for all of the HDAC isozymes, with pH optima

135 (M)-pH profiles with N(1)-acetylspermine are bell-shaped for all the mutants; the similarity to the p

136 t)/K(m)(L-OSHS) versus pH profile of eCGS is bell-shaped for both reactions.

137 The resistive component is bell-shaped for both voltage and frequency.

138 erating effects on heparin concentration was bell-shaped for ZPI reactions with both factors Xa and X

139 f STIM1, CRAC current was a highly nonlinear bell-shaped function of Orai1 expression and the minimum

140 ies or nonrecombining chromosome region is a bell-shaped function of the mutation rate: at some point

141 ma distribution, which is in contrast to the bell-shaped Gamma distribution when the gene effects wer

142 speed tuning curves of MT neurons should be bell-shaped (Gaussian) as a function of the logarithm of

143 Saturating HCII dependences and bell-shaped heparin dependences of the fluorescence chan

144 In computational models, such a bell-shaped "hill of activity" is commonly assumed to be

145 (R2N)PPn(+*) further show that the symmetric bell-shaped hole distribution distorts and shifts toward

146 merizes via the FAD-binding domain to form a bell-shaped homodimer in solution with a maximal dimensi

147 endence of phasic contraction which was more bell-shaped (i.e. more similar to that of ICa,L) than th

148 Cyclosporine treatment caused bell-shaped improvements in cardiac output, stroke volum

149 h model, our data suggest that MK has a dumb-bell shape in solution composed of independent N- and C-

150 The voltage-contraction relationship was bell-shaped in Na+-free solutions (to eliminate the Na+

151 tate concentration-response curves that were bell-shaped in response to either glutamate or AMPA.

152 tionship between contraction and voltage was bell-shaped in the absence of Na-Ca exchange.

153 The time course of D was bell-shaped, indicating it was an intermediate.

154 me modest effects, the shapes of neither the bell-shaped k(cat)/S(0.5)-pH (and related functions) plo

155 The bell-shaped logarithmic GAG dependences fit an obligator

156 rge of the membrane motor is manifested as a bell-shaped membrane potential dependence of the membran

157 trong plasmonic coupling effect, and (iii) a bell-shaped nanostructure that can effectively amplify t

158 For both proteins, the bell shape of this dependence shows that they autoxidize

159 ctural units (dialkyammonium groups) in dumb-bell-shaped organic molecules template the assembly of e

160 ore fatty acid synthesis enzymes displayed a bell-shaped pattern of expression between 5 and 13 days

161 males), and, respectively, showed a U- and a bell-shaped pattern with age.

162 rmal eyes and optic nerve crush alone showed bell-shaped patterns of change: approximately 50% below

163 is qualitatively different from the largely bell-shaped patterns typical of EMG activity associated

164 the chemical shift analysis, nonuniform and bell-shaped peak intensity profiles, and limited proteol

165 The concept of bell-shaped persistent neural activity represents a corn

166 ssociated with a rate constant that showed a bell-shaped pH dependence indicative of participation of

167 Furthermore, we conclude that the simple bell-shaped pH dependence of k(cat) and k(cat)/K(m) for

168 The bell-shaped pH dependence of permeability suggests that,

169 Furthermore, the wild-type hydratase shows a bell-shaped pH dependence of the kcat/Km with pKa values

170 o-step mechanism is also consistent with the bell-shaped pH dependence of the reaction rate.

171 In addition, normal bell-shaped pH dependence on the reaction catalyzed by M

172 The bell-shaped pH dependence upon pK(app)'s of 7.1 and 9.1

173 -)(CoA), and V/K(homoserine) all exhibited a bell-shaped pH dependence with apparent pK's of 6.6 and

174 (kcat/Km)app and kred/Kd exhibit comparable bell-shaped pH dependence with pKa values of 6.4 +/- 0.2

175 lated cytochrome c(3+) reduction displayed a bell-shaped pH dependence with the protonation of a grou

176 ecovery to the colored ground state showed a bell-shaped pH dependence, controlled by two pKa values

177 Formation of this complex exhibits bell-shaped pH dependence, with pKa values of 6.5 and 7.

178 ameter klim/Kd for the fast phase exhibits a bell-shaped pH dependence, with two pKa values of 9.3 +/

179 A bell-shaped pH profile and salt concentration dependence

180 s ranging from minutes to hours, exhibited a bell-shaped pH profile for k(bkdn), typical of the pH-ra

181 The simulation data reveal a bell-shaped pH profile for the total helix content, in a

182 he k(cat)/K(M) value for spermine exhibits a bell-shaped pH profile, with an average pK(a) value of 8

183 The k(cat)/K(m) value for BESPM exhibits a bell-shaped pH profile, with pK(a) values of 9.8 and 10.

184 Both bell-shaped pH profiles are quantitatively accounted for

185 pKa values range from 7.0 to 8.7) exhibited bell-shaped pH profiles whose maxima were distinct for e

186 strated that the mutant proteases maintained bell-shaped pH profiles, as well as suicide-inhibitor su

187 finity of MKP3 for oxyanion, and restore the bell-shaped pH rate profile for the MKP3-catalyzed react

188 ysis of bulky polycyclic substrates exhibits bell-shaped pH rate profiles in the absence of ERK2.

189 from RNase A and serve to generate a similar bell-shaped pH versus k(cat)/K(M) profile for RNA cleava

190 Bell-shaped pH versus rate profiles were observed for V(

191 These measurements show bell-shaped pH-rate curves for each enzyme in the presen

192 A bell-shaped pH-rate profile for k(cat) and k(cat)/K(m) i

193 yl phosphate (4NPP), the reaction exhibits a bell-shaped pH-rate profile for kcat/KM indicative of ca

194 bstrate Cdk2-pTpY/CycA, however, did yield a bell-shaped pH-rate profile with a pK(a) of 6.1 for the

195 stingly, Cdc25B does not exhibit the typical bell-shaped pH-rate profile with small molecule substrat

196 gnificant shift in pK(1) to higher pH in the bell-shaped pH-rate profiles (k(cat)/K(m)) for several p

197 Both YopH and Cdc25A exhibit bell-shaped pH-rate profiles for the hydrolysis of mNBP,

198 The existence of bell-shaped pH-rate profiles for the K73A variant sugges

199 ypoxanthine and 1,N(6)-ethenoadenine follows bell-shaped pH-rate profiles, indicating that AAG-cataly

200 a 1 gamma 2S delta constructs resulted in a 'bell-shaped' pH titration relationship.

201 MAD2 complex is cell cycle regulated with a "Bell" shaped profile and peaks at prometaphase.

202 A bell-shaped profile of the observed rate constant for an

203 diates was measured and exhibited an unusual bell-shaped profile over the pH range of 5.0-9.5 with a

204 ate of assembly depends on the pH level in a bell-shaped profile, and two pK(a) values that are in go

205 for isoleucyl 4-cyanothiazolidide yielded a bell-shaped profile, with pK(a)=5.0 and pK(b)=7.6.

206 he pH dependence of the IMPDH reaction shows bell-shaped profiles for kcat and the kcat/Km values for

207 The broad and bell-shaped profiles representing the diversity of the V

208 Bell-shaped profiles were observed for k(cat) and k(cat)

209 Bell-shaped profiles were observed for kcat and kcat/Km

210 en expression for the urease reaction with a bell-shaped rate-pH dependence.

211 Among all nelfinavir-treated patients, a bell-shaped relationship between adherence and the risk

212 The standard view postulates a bell-shaped relationship between adherence to therapy an

213 atients with detectable viremia, there was a bell-shaped relationship between Gag-specific CD4+ T cel

214 A distinct bell-shaped relationship between lung volume and carbon

215 These characteristics produce a bell-shaped relationship between the apparent dissociati

216 ch case, superoxide production had a similar bell-shaped relationship to the reduction state of cytoc

217 A bell-shaped relationship was also observed for the proba

218 tatic conditions, cell migration speed had a bell-shaped relationship with fibronectin concentration.

219 unctional conductance (G(j)), which showed a bell-shaped relationship with junctional potential (V(j)

220 nt of shortening blocked by nifedipine had a bell-shaped relationship with voltage, whereas the "nife

221 We observe an asymmetric, approximately bell-shaped, relationship between the average intracellu

222 Bell-shaped relationships between adherence and resistan

223 te but produced an increase (potassium) or a bell-shaped response (rubidium) with a supercoiled templ

224 nocytes, neutrophils, and macrophages with a bell-shaped response curve in a pertussis toxin-sensitiv

225 e.g. dihydrorhodamine) previously revealed a bell-shaped response to co-generated (*)NO and O(2) flux

226 The activity of the enzyme exhibited a bell-shaped response to divalent cations and pH.

227 Similar bell-shaped results were found when the GRT analysis was

228 at which superoxide oxidation ensued yielded bell-shaped ring currents.

229 elationship in 200 microM cadmium (Cd2+) was bell-shaped, supporting a role of ICa,L rather than VDCR

230 ified size related changes in wake dynamics, bell shape, swimming and turning kinematics of two speci

231 le Pb2+ concentration was found to exhibit a bell shape that spans approximately 3 orders of magnitud

232 xhibit distinct pH dependence (the former is bell-shaped, the latter sigmoidal), again consistent wit

233 al ischemia-reperfusion (MI/R) injury with a bell shape therapeutic profile.

234 These data generate classic bell-shaped time-constant-potential curves.

235 nd C(20):C(20:3Delta11,14,17)PE, an inverted bell-shaped Tm profile was detected in the plot of Tm ag

236 have shown that the information conveyed by bell-shaped tuning curves increases as their width decre

237 Numerosity-selective neurons showed bell-shaped tuning curves with one of the presented nume

238 ivities of large populations of neurons with bell-shaped tuning curves.

239 Simulations are performed for both an oblate bell shape using a paddling mode of swimming and a prola

240 ng a paddling mode of swimming and a prolate bell shape using jet propulsion.

241 of episodes, each consisting of a distinct, bell-shaped velocity profile (submovement) that rarely o

242 pear to be consistent with the arm-referent, bell-shaped, visual target tuning curves and target sele

243 A bell-shaped voltage dependence and modest sensitivities

244 hannel current (I(Ca)), and it shifted their bell-shaped voltage dependence leftward by approximately

245 -cAMP, membrane-permeable form of cAMP), the bell-shaped voltage dependence of cytosolic Ca2+ transie

246 ISO dramatically broadened the bell-shaped voltage dependence of intracellular Ca(2+) t

247 Confocal imaging revealed that the bell-shaped voltage dependence of SR Ca(2+) release is a

248 ials and the I-V relationship maintained its bell-shaped voltage dependence.

249 nd total amount of released Ca2+ exhibited a bell-shaped voltage dependence.

250 mplitude of the Ca2+ transient also showed a bell-shaped voltage dependence.

251 plitude of the Ca2+ transient again showed a bell-shaped voltage dependence.

252 ntraction in physiological [Na+] and a broad bell-shaped voltage-contraction relationship was observe

253 K(+)-based, Na(+)-free solution exhibited a 'bell-shaped' voltage dependence of the L-type Ca2+ chann

254 in's voltage sensor imparts a characteristic bell-shaped, voltage-dependent nonlinear capacitance (NL

255 ies rapidly decay with decreasing Re for all bell shapes when Re<10.

256 Dose response curves showed bell shapes where activity was low at low and high conce

257 tinociception display ceiling effects or are bell shaped, which have been attributed to the partial a

258 ance spectra of visual pigments have a broad bell shape with the peak, being called lambdamax.

259 The V profile is bell shaped with slopes of 1 and -1, giving pKa values o

260 voltage dependence of phasic contraction was bell-shaped with 0 Na+, became much loss bell-shaped wit

261 was bell-shaped with 0 Na+, became much loss bell-shaped with 10 mM Na+ and with 20 mM Na+ the phasic

262 We found that the distribution is nearly bell-shaped with a peak at 50 base pairs (bp) upstream o

263 The (catR)/ versus pH profile of ytCBS is bell-shaped with a pH optimum of 8.3, and the pK(a) valu

264 The pH-k(cat) profile is bell-shaped with a pK(a) of 6.4 +/- 0.1 for the ascendin

265 he pH dependence of k(cat)/K(m,phosphite) is bell-shaped with a pK(a) of 6.8 for the acidic limb and

266 ip (assessed 45 min after DPAT injection) is bell-shaped with an ED50 approximately 1 mg/kg on the as

267 The pH dependence of V/K was bell-shaped with apparent pKs of 6.5 and 8.3.

268 By contrast, the doxorubicin response was bell-shaped with high doses failing to increase H2AX pho

269 The activity dependence on pH was bell-shaped with highest activity between pH 6.8 and pH

270 ate 2b, which lacks a 6-carboxyl group, were bell-shaped with limiting slopes of unity on both sides

271 dase activity and beta-lactam acylation were bell-shaped with maximal activity at pH 8.0-8.5.

272 tionship predicted by the CICR hypothesis is bell-shaped with no contraction at ECa.

273 profile of V/K for L-ribulose 5-phosphate is bell-shaped with pK values of 5.94 and 8.24.

274 the substrate Abz-LPETG-Dap(Dnp)-NH(2) were bell-shaped with pK(a) values of 6.3 +/- 0.2 and 9.4 +/-

275 versus pH profiles with and without CaM were bell-shaped with the ionization of a group at pK(a) of 7

276 ons in LiCl with and without MgCl2 were both bell-shaped with the pH optima in the neutral range.

277 or the observed first-order rate constant is bell-shaped with two ionizable groups of pK(a) 4.9 and 5

278 tion spectra of visual pigments have a broad bell shape, with the peak being called lambda(max).

279 aF/F versus voltage curve, from sigmoidal to bell-shaped, with a maximum at approximately +30 mV.

280 taining a pro-alpha factor cleavage site was bell-shaped, with a maximum near pH 4.0.

281 (III) as a function of SCN- concentration is bell-shaped, with a trough comparable with normal SCN- p

282 pH dependence of kcat/Km for L-kynurenine is bell-shaped, with apparent pKa's of 6.25 +/- 0.05 on the

283 e of kcat/Km for 3-hydroxykynurenine is also bell-shaped, with apparent pKa's of 6.49 +/- 0.07 and 8.

284 rves for these T-cell activation markers are bell-shaped, with different maxima and midpoints, depend

285 The plot of log k(cat)/K(m) versus pH is bell-shaped, with fitted pK(a) values of 6.76 +/- 0.09 a

286 The k(cat)/K(sarc) pH profile is bell-shaped, with pK(a) values of 8.8 and about 10; the

287 against Ac2-l-Lys-D-Ala-d-Ala (kcat/Km) was bell-shaped, with pKa values at 6.9 and 10.1.