ライフサイエンスコーパス: benefit

1 practices conferred no additional mitigation benefit.

2 ify those patient populations most likely to benefit.

3 reverse remodeling but the same symptomatic benefit.

4 Joint treatment provided a small incremental benefit.

5 actionated radiotherapy showing the greatest benefit.

6 test but had no antidepressant or anxiolytic benefit.

7 e only reasonably likely to predict clinical benefit.

8 essibility of compounds with putative health benefit.

9 es costs while providing minimal incremental benefit.

10 t with taxanes and irinotecan, provides some benefit.

11 to the amount of the previously-reported EAS benefit.

12 ence, but was in a direction consistent with benefit.

13 protein late, during adulthood, is devoid of benefit.

14 fee-for-service coverage including pharmacy benefits.

15 ignoring research on economic/environmental benefits.

16 atural pigment, also adding potential health benefits.

17 d by its numerous economic and environmental benefits.

18 f each patient's unique balance of risks and benefits.

19 = 12 h every day exerts many cardiometabolic benefits.

20 antimicrobial compounds for food and health benefits.

21 , when implemented properly, can convey many benefits.

22 rough gene therapy might provide therapeutic benefits.

23 first-line antidepressants offer therapeutic benefit, about 35% of depressed patients are not adequat

24 traumatic spinal contusion injury in mice, a benefit achieved in part by reducing macrophage-mediated

25 To evaluate the survival benefit achieved through surgical resection of melanoma

26 h SPRM above the median derived the greatest benefit (adjusted HR: 0.599; 95% CI: 0.530 to 0.677; p <

27 may have a predictive value for the clinical benefit after chronic DBS that could be used to improve

28 To balance potential antibacterial benefit against risk of nephrotoxicity the algorithms we

29 improved survival and may offer therapeutic benefit among carefully selected patients.

30 ic co-trimoxazole seems to offer no survival benefit among HEU children in non-malarial, low-breastfe

31 meta-analysis demonstrates a significant OS benefit and confirms the PFS benefit with lenalidomide m

32 en the host and its microbiota are of mutual benefit and promote health.

33 CCR2 deficiency does not provide a sustained benefit and that Ly6C(low) MPs may contribute to the pro

34 nd progression if deriving apparent clinical benefit and tolerating study drug, at the investigator's

35 We do so by considering the social benefits and costs of confrontational types of proactive

36 As a case study, we assess the benefits and costs of treating wet flue gas desulfurizat

37 To systematically review the benefits and harms associated with thyroid cancer screen

38 The benefits and harms of dual antiplatelet therapy (DAPT) c

39 current review assessed new evidence on the benefits and harms of folic acid supplementation.

40 Evidence to estimate benefits and harms of preeclampsia screening and the tes

41 To review the evidence on benefits and harms of screening for celiac disease in as

42 older based on a periodic discussion of the benefits and harms of specific blood pressure targets wi

43 The benefits and impacts of unconventional natural gas devel

44 urity, and aerial imagery), but the expected benefits and merits of using different pooling algorithm

45 Each approach produces substantial benefits and net cost savings relative to the status quo

46 Additionally, the review addresses the benefits and risks of routine measurement of thiopurine

47 It is important to recognize the potential benefits and trade-offs of decentralized and centralized

48 mputer-based simulation allows assessment of benefits and tradeoffs of the alternative schedule witho

49 , competing causes of death may diminish the benefit, and there is no evidence to recommend screening

50 ted research resources, to maximise research benefit, and to help minimise research waste.

51 physical activity and its associated health benefits are hindered by poor urban infrastructure.

52 These benefits are sustained to 1 year and support the "real-w

53 American College of Cardiology members have benefited as funding of the entire cohort has decreased.

54 ter long-term treatment results in continued benefit, as evidenced by improved symptom control and re

55 n, and gluten-free diet, may have additional benefits, as do potential noninvasive and invasive proce

56 the first estimates of the fitness cost and benefit associated with resistance of the gonococcus to

57 to Adult Health, we test whether the health benefits associated with college completion vary by leve

58 l care population has clinical and financial benefits associated with its implementation and should b

59 While there was no observable benefit at early time points after transplantation, both

60 ead holds both increased health and economic benefits because of combined roles as soluble dietary fi

61 ific therapy is unlikely to offer additional benefits, because survival rates have reached a plateau.

62 n and treatment effect, the overall survival benefit being restricted to the hyperfractionated group

63 lbicans-P. aeruginosa cross talk in vivo can benefit both organisms to the detriment of the host.

64 This platform will greatly benefit both researchers and clinicians for interrogatin

65 Cooperative behaviors provide a collective benefit, but are considered costly for the individual.

66 ty on children are frequently shown to be of benefit, but effect sizes are typically small to moderat

67 Fish oils have many dietary benefits, but due to their strong odors and rapid deteri

68 es in a modular architecture, have potential benefits, but need to be explored further.

69 e change adaptation potential and ecological benefits by buffering alley crops to weather extremes, d

70 s study are the first suggestion of improved benefit compared with anti-PD-1 monotherapy in patients

71 trated that TAVR has a significant mortality benefit compared with medical therapy and a similar bene

72 compared with medical therapy and a similar benefit compared with surgery.

73 cussion with patients about potential harms, benefits, costs, and patient preferences.

74 tline how thermal environment will alter the benefits/costs of infection more widely, and additionall

75 These benefits could accrue due to larger group sizes in gener

76 r access to and distribution of health care, benefits coverage, coordination of care across sectors,

77 However, some benefits derived from phytanic acid intake have also bee

78 ires additional information on the long-term benefits (e.g., life-years gained and mortality reductio

79 rational choices are associated with direct benefits, enabling males to maximize offspring productio

80 alternatives are available, 2) the objective benefit exceeds the risk, and 3) patients are fully info

81 ponse, whereas 80% of patients with clinical benefit exhibited PD-1+ CD8 T-cell responses within 4 wk

82 Although MUTT II could not find a benefit for all corneal ulcers, Fusarium keratitis may b

83 would indicate a clear expected net clinical benefit for anticoagulating AF patients with CHA2DS2-VAS

84 that characterize IgAN indicate a potential benefit for corticosteroids.

85 INTERPRETATION: No evidence of benefit for ketamine was found although the sample size

86 cell culture and sorting via FACS will be of benefit for researchers performing this protocol.

87 ly for 3 years, there is persistent clinical benefit for several years after its discontinuation.

88 he BELIEF trial provides further evidence of benefit for the combined use of erlotinib and bevacizuma

89 Furthermore, they have many additional benefits for human health, such as anti-oxidant, antivir

90 al microcompartments might yield significant benefits for pathway flux, as well as for toxicity mitig

91 high-volume hospitals; however, case volume benefits for transferred patients may be limited to pati

92 vides evidence to support no overall outcome benefit from adjuvant anthracyclines in patients with ea

93 Most patients derive clinical benefit from adrenalectomy, with younger patients and fe

94 Advantageous foraging choices benefit from an estimation of two aspects of a resource'

95 atient risk and to identify patients who can benefit from angiotensin receptor blocker treatment.

96 arkers that predict which mRCC patients will benefit from antiangiogenic therapy.

97 Evidence suggests no benefit from bronchodilator or corticosteroid use in inf

98 ltiple additional classes of cancer that may benefit from CDK4/6-inhibiting drugs such as abemaciclib

99 EF can identify patients with COPD who would benefit from currently available therapy and require fur

100 Nursing science might benefit from deeper involvement in engineering research

101 efficacy is leading many patients who could benefit from drug therapy to not take these drugs.

102 score identified those experiencing the most benefit from extended treatment among patients with and

103 BRCA mutation younger than 40 years may not benefit from FFD mammography surveillance in addition to

104 many plants, animals, and ecosystem services benefit from fire, it is unknown how ecosystems will res

105 ry is critical to identify families who will benefit from genetic testing, determine the best strateg

106 MSM not attending GUM clinics will partially benefit from herd protection.

107 d hemisphere (COVES = 0) appeared to have no benefit from IAT, whereas patients with venous opacifica

108 enous opacification (COVES >0) were shown to benefit from IAT.

109 ilial adenomatous polyposis (FAP), signal of benefit from imaging-based early detection research in h

110 der people in deprived communities who would benefit from investing in grandchildren.

111 Likewise, animals benefit from knowledge parsing their environment into la

112 fforts to enhance RTS,S/AS01E efficacy would benefit from learning about the vaccine-induced immunity

113 results suggest transfemoral amputees could benefit from load-adaptive powered knee controllers, and

114 evidence base to enable black women to fully benefit from prevention research advances and decrease r

115 ed patients less likely to derive a survival benefit from primary prevention ICDs.

116 hers outside of the C. elegans community can benefit from public mappings and integrated tools for co

117 tics of the lacrimal punctum in patients who benefit from punctoplasty.

118 rom very shallow water bodies (few mm depth) benefit from reduced predation risk, but by manipulating

119 Only one case report suggested benefit from selective serotonin reuptake inhibitor/sero

120 More experienced cataract surgeons did not benefit from simulator training.

121 ith the selection of patients most likely to benefit from stress testing after PCI.

122 ility in identifying patients most likely to benefit from targeted anti-interleukin and anti-immunogl

123 ntified vulnerable subpopulations that could benefit from targeted interventions.

124 r all corneal ulcers, Fusarium keratitis may benefit from the addition of oral voriconazole to topica

125 ke or myocardial infarction (MI) derive more benefit from the insulin-sensitizing drug pioglitazone h

126 ng of tau pathology in Alzheimer disease may benefit from the use of white matter reference regions.

127 biomarkers that predict which patients will benefit from these therapies.

128 are warranted to identify patients who might benefit from this therapy.

129 cing and to determine whether these patients benefit from upfront biventricular pacing.

130 yet been established, and some patients may benefit from Vts that are lower than those in current us

131 The latter assume that modern humans benefited from some selective advantage over Neanderthal

132 owledge of pathogen life history has greatly benefited from the advent and development of molecular e

133 ough the development of Hsp90 inhibitors has benefited from the identification of clients, such as Ra

134 tress and increase global food productivity, benefiting from [CO2] rich environments.

135 of drug development that, rather than simply benefiting from a patient-specific approach, actually de

136 Benefiting from the high surface area, mesoporous struct

137 Benefiting from the unique porous holey nanostructure an

138 a compromise between clock stability, which benefits from a large number of atoms, and accuracy, whi

139 (WGS) next-generation sequencing (NGS) data benefits from high-quality input with high coverage.

140 This study aims to analyze the antioxidant benefits from persimmon leaf tea, fruit and fibres takin

141 In cases where the central regulator benefits from the polluting activity, we argue that ther

142 trength of underlying evidence and potential benefit gained by early detection and appropriate manage

143 The benefits, harms, and feasibility of implementing lung ca

144 on outweighs the bleeding risk (net clinical benefit) has been shown to be approximately 1% to 2%.

145 sis, AC was associated with a significant OS benefit (hazard ratio, 0.77 [95% CI, 0.68 to 0.88]; P <

146 pared with PCI, CABG still showed a survival benefit (hazard ratio, 0.82; 95% confidence interval, 0.

147 e blue-violet light filter showed functional benefit in all evaluated patients.

148 er (death), and (3) clinical usefulness (net benefit in decision curve analysis) by identifying risk

149 RT boost confers a statistically significant benefit in decreasing IBTR across all DCIS age groups, s

150 INTERPRETATION: We noted no survival benefit in men with metastatic castration-resistant pros

151 r intravenous thrombolysis (IVT) is of added benefit in patients undergoing MT.

152 or metastatic colorectal cancer has clinical benefit in patients with colorectal liver metastases wit

153 neutralize toxin activity provide a survival benefit in preclinical animal models and prevent recurre

154 nscriptional memory confers a strong fitness benefit in Saccharomyces cerevisiae adapting to growth i

155 Folic acid supplementation confers modest benefit in schizophrenia, but its effectiveness is influ

156 hial valve (EBV) treatment have demonstrated benefit in severe heterogeneous emphysema.

157 To evaluate the additional benefit in terms of cost-effectiveness of colonoscopy su

158 There was no OS benefit in the experimental arm (median, 21.8 v 24.5 mon

159 gins, highlighting objects likely to provide benefit in the future.

160 sing the PAK pathway might be of therapeutic benefit in this type of melanoma.

161 ribose) polymerases (PARPs) elicits clinical benefits in cancer therapy.

162 Measuring these benefits in collaboration with the risk modelling indust

163 have demonstrated their environmental health benefits in field settings.

164 aptive cognitive training appears to have no benefits in healthy young adults above those of standard

165 institutional experience, in which postshunt benefits in patients with initial diagnosis of idiopathi

166 ransfusion that need to be weighted with its benefits in selected patients.

167 mined that both regimens provided comparable benefits in terms of annexin gene expression and muscle

168 o 3 years of tamoxifen can lead to sustained benefits in terms of reduction of disease recurrence and

169 low nasal oxygen has recently shown survival benefits in unselected patients with acute respiratory f

170 Benefits included the flexibility of the approach, the h

171 ns, dietary restriction (DR) grants numerous benefits, including enhanced learning.

172 whereby DcpS inhibition leads to therapeutic benefit is unclear.

173 Effective evaluation of costs and benefits is a core survival capacity that in humans is c

174 Relatively isolated subpopulations benefit little from high surrounding population immunity

175 tion for type I diabetes, the more immediate benefit may be for the exploration of revascularized isl

176 ns, suggest different constructs of clinical benefit measured.

177 nd mortality are some of the common clinical benefit measures incorporated into CEA.

178 ty to regulate complement activation and may benefit more from complement-inhibiting therapy than pat

179 INTERPRETATION: Colonoscopy surveillance benefits most patients with intermediate-risk adenomas.

180 ategy will create a network effect that will benefit multiple disease programs.

181 The primary outcome measure was net health benefit (NHB), which was measured as quality-adjusted li

182 s the upper limit for collective integration benefits obtained by weighted averaging of people's conf

183 have been developed, aiming on the combined benefit of a local irradiation of the analyzed sample an

184 In IMPROVE-IT, the benefit of adding ezetimibe to statin was enhanced in pa

185 The benefit of adding sentinel node biopsy (SNB) to extended

186 tion radiotherapy regimens and to assess the benefit of altered fractionation within the context of c

187 old of annual ischemic stroke rate where the benefit of anticoagulation outweighs the bleeding risk (

188 The review also highlights the benefit of combining experimental and theoretical studie

189 To determine dominant pulse sequence and benefit of dynamic contrast-enhanced (DCE) imaging, odds

190 ON: Our findings show a clinically important benefit of enhanced social recovery on structured activi

191 Phase 1 studies have shown potential benefit of gene replacement in RPE65-mediated inherited

192 Antibiotics inhibited the clinical benefit of ICIs in patients with advanced cancer.

193 Given the potential benefit of immunotherapy, implementation of current and

194 Transmission has the benefit of increasing herd immunity above that achieved

195 or even exploit autophagy mechanisms for the benefit of infection.

196 The benefit of initiation of insulin pump therapy (continuou

197 randomised controlled ASTIC trial showed no benefit of mobilisation and autologous haematopoietic st

198 low- to middle-income countries to study the benefit of pneumococcal conjugate vaccine (PCV) in prote

199 The projected cost-effectiveness and cost-benefit of preventive chemotherapy were very promising,

200 the risk of developing DM and the potential benefit of replacing SSBs with ASBs or water.The nationa

201 The clinical benefit of sorafenib in patients with hepatocellular car

202 cancer incidence and mortality; however, the benefit of surveillance colonoscopy on colorectal cancer

203 n treated by prostatectomy that assessed the benefit of the Decipher test.

204 y treatment may be necessary to maximize the benefit of the drug.

205 ates in a deterministic manner, negating the benefit of the larger state space.

206 The benefit of ticagrelor 60 mg was consistent at each subse

207 otic Ulcer Treatment Trial (MUTT) I showed a benefit of topical natamycin over topical voriconazole f

208 ICU patients with stable renal function, the benefit of using sodium bicarbonate rather than isotonic

209 n that stems from our results reinforces the benefits of 2 key components of the Mediterranean diet (

210 tagonists for the hA3AR, and exemplifies the benefits of a joint theoretical-experimental approach to

211 future researchers to evaluate the costs and benefits of adding sequenced genomes to transcriptome da

212 ced diet may extend beyond the mere physical benefits of adequate nutrition.

213 Current evidence continues to support the benefits of an earlier rather than delayed introduction.

214 These data highlight the potential benefits of BACE inhibition for the effective treatment

215 ual selection in social species whenever the benefits of building new bonds outweigh the costs.

216 and not considering other health and social benefits of cash transfers.

217 nfection may be required to realize the full benefits of CFTR-targeting treatments.

218 health resilience and adaptation; health co-benefits of climate change mitigation; economics and fin

219 Further studies examining potential benefits of combination lipid-lowering therapy in indivi

220 with increased appreciation of the potential benefits of combining attractive features of both homoge

221 The study demonstrated that the benefits of crowdsourcing are not restricted only to har

222 of ST, resource requirements for ST, and the benefits of early treatment, data do not support delayin

223 fected populations are needed to realise the benefits of existing interventions.

224 ok a comprehensive meta-analysis to quantify benefits of hypothermia therapy for traumatic brain inju

225 teel based anode materials, and the emerging benefits of inclusion of nanomaterials.

226 ns the reported cardiovascular disease (CVD) benefits of intensive BP lowering in this population.

227 gimens, summarize the evidence on the health benefits of intermittent fasting, and discuss physiologi

228 od effects also help explain how and why the benefits of interventions vary between slum and non-slum

229 The benefits of land sparing for both biodiversity and carbo

230 The benefits of MR antagonism in the pig provide a rational

231 These studies demonstrated the clinical benefits of nepafenac 0.3% over vehicle in reducing the

232 cting randomized trials to explore risks and benefits of OAT resumption after ICH.

233 resent its first application to evaluate the benefits of ozone reductions for low-income households.

234 their augmentation could help to broaden the benefits of renin-angiotensin system inhibitors for pati

235 ategy may enable the parasite to balance the benefits of the enhanced host catabolic activity with th

236 Despite the occupational safety benefits of these new explosives, feasible strategies fo

237 sis for future clinical trials assessing the benefits of this approach in patients with IR-mediated A

238 We discuss both the potential benefits of this method for helping individuals make bet

239 The key benefits of this reaction include the use of metal-free,

240 tionary simulations to incorporate costs and benefits of two coevolving costly traits: cooperative an

241 ation in collections demonstrates the mutual benefits of undergraduate involvement.

242 are long-standing interests in the potential benefits of vitamin D for preventing breast cancer recur

243 en compared with saline (5.54, 3.42), had no benefit on the primary outcome (HVLT-R-DR; difference in

244 =0.007), and exerted a significant ischaemic benefit only in this latter group.

245 e and euthanasia in medical practice: 1) the benefit or harm of death itself, 2) the relationship bet

246 s disease, and identify factors that predict benefit or harm.

247 Our results suggest that the benefit or risk associated with intensive blood pressure

248 There was no direct evidence on the benefits or harms of screening children and adolescents

249 extra year, 0.93-0.98; p<0.001) and clinical benefit (OR 0.95 per extra year, 0.92-0.98; p=0.004).

250 cal decompression appeared to offer no extra benefit over arthroscopy only.

251 where introduction of silicon has created a benefit over its analog.

252 rs and development of treatment solutions to benefit patients with breast cancer at high risk of recu

253 Continuous renal replacement therapy (CRRT) benefits patients with renal failure who are too hemodyn

254 to address whether wildflower gardens, while benefiting pollinators, could also hasten the extinction

255 tically modified porcine organs with CHC may benefit post-transplant xenograft function.

256 0%) are efficient to abate, resulting in net benefits ranging from $160M to $1.2B annually across the

257 ld be de-listed, whereas patients with large benefit ratio should be prioritized for LT.

258 e use, a clear understanding of the clinical benefits relative to costs is essential for both appropr

259 ts produces abnormal evaluation of costs and benefits resembling non-optimal decision-making in which

260 of current tools and processes used for its benefit-risk assessment is critical.

261 Patients without benefit should be de-listed, whereas patients with large

262 Aviation and space applications can benefit significantly from lightweight organic electroni

263 can accelerate their structural analysis and benefit specific studies in allergology.

264 ation and super-resolution imaging, offering benefits such as high photostability, large signal-to-no

265 SIRS had lower net benefit than qSOFA and CRB, significantly increasing the

266 future UWM that offers significant potential benefits thanks to increased collection and utilization

267 ten remembered better than neutral events, a benefit that many studies have hypothesized to depend on

268 feature space, we select features that best benefit the classification scheme in the kernel space.

269 This process benefits the pathogen since it enhances bacterial disper

270 While host protein synthesis shutoff benefits the virus by relocating cellular resources to v

271 se that this trade-off, consistent with cost-benefit theory, represents a significant physio-phenolog

272 ts and reducing the hs-CRP level may further benefit this population.

273 l drug cost than did those that did not meet benefit thresholds (US$2981 [IQR 320-9059] vs $8621 [117

274 Treatments that met ESMO benefit thresholds had a lower median incremental drug c

275 balance behaviors, suggesting a therapeutic benefit to balance with ASO-29 treatment at P15 despite

276 on in cumulative tumor load, suggesting most benefit to be gained by early conversion to an mTOR inhi

277 ile surface fluorination process brings huge benefit to both the existing lithium-ion batteries and n

278 e provide a tremendous and easily recognized benefit to individuals and society.

279 h program has provided exceptional value and benefit to the American public through its research prog

280 r whom college completion is associated with benefits to both mental and physical health.

281 In 2006, additional benefits to fetal growth from the pregnancy-specific rat

282 ily injections of insulin provide lifesaving benefits to millions of diabetics.

283 of the scientific process, and its potential benefits to society.-Flier, J.

284 ed by DACA, could confer large mental health benefits to such individuals.

285 ts) were evaluated, demonstrating the health benefits to the populations during the ten years.

286 results suggest that there may also be large benefits to vaccinating previously infected individuals.

287 related signatures correlating with clinical benefit using a learn-and-confirm paradigm based on data

288 tional mechanisms underlying subjective cost-benefit valuation across different domains of effort and

289 induces autophagy and cell cycle arrest and benefits virus replication.

290 BENEFIT was a randomized clinical trial comparing early

291 0.66-0.85, p<0.0001), whereas no significant benefit was observed among those with on-treatment hsCRP

292 No harm or benefit was observed for myocardial infarction, stroke,

293 gina relief, although the absolute treatment benefit was small.

294 Benefits were measured in quality-adjusted life-years ga

295 e to evolved trade-offs can yield phenotypic benefits, whereas slow development from low temperature

296 ts excluded greater than a small to moderate benefit with 95% confidence.

297 The association of cognitive benefit with DHA supplementation in predementia but not

298 significant OS benefit and confirms the PFS benefit with lenalidomide maintenance after ASCT in pati

299 dial infarction, there may be no significant benefit with single-stage MV-PCI compared with CO-PCI.

300 ete, curative resection derived the greatest benefit, with a median OS of 64 months.