ライフサイエンスコーパス: bent conformation

1 inhibition, and in solution adopts a stable bent conformation.

2 ts to restrain the I domain in the inactive, bent conformation.

3 intact alpha(IIb)beta(3) adopted a compact, bent conformation.

4 bbeta3 results from alphaIIbbeta3 adopting a bent conformation.

5 and extended-open conformations as well as a bent conformation.

6 ences with A:T-rich spacers that adopt a pre-bent conformation.

7 r between the labeled ends of the DNA in the bent conformation.

8 monovalent ligands and basally retained the bent conformation.

9 on one H chain by adopting an asymmetrically bent conformation.

10 ence of the presence of alpha(L)beta(2) in a bent conformation.

11 accommodate a protein moiety in its severely bent conformation.

12 It has an overall bent conformation.

13 ion, demonstrating that these sites are in a bent conformation.

14 opulations in all states called straight and bent conformations.

15 (dsDNA) in low-probability, cyclic or highly bent conformations.

16 s the tropomyosin molecule to adopt multiple bent conformations.

17 complexes showed that FAD adopted an unusual bent conformation, allowing its ribityl side chain and A

18 e accommodates chromosomal DNA in a severely bent conformation, allowing widely spaced IN active site

19 Bent conformation and chain prenylation, were molecular

20 The structure reveals a bent conformation and defines the alpha-beta interface b

21 eptor distance, which is consistent with the bent conformation and does not change in the activated i

22 es suggest that all CNTN ectodomains adopt a bent conformation and might lie parallel to the cell sur

23 d high affinity for ligand, whereas both the bent conformation and the extended-closed headpiece conf

24 d that it depends both on its characteristic bent conformation and two conserved RNA motifs, an apica

25 They transitioned between a bent conformation and two extended conformations in whic

26 peptide, containing three prolines, adopts a bent conformation, and the C-terminal segment of the pep

27 Coenzyme A binds in a bent conformation, and the details of its interactions a

28 ll to an alphaIIbbeta3 construct locked in a bent conformation, and unlocking the conformation restor

29 ences at their stem junctions imply the same bent conformation as in the mouse mammary tumor viral RN

30 ke domain that adopts either a straight or a bent conformation at various positions along the length.

31 The opened duplex manifests a bent conformation (bending angle approximately 60 degree

32 icated a cognate cis interaction between the bent conformation beta5/beta3 integrins and an arginine-

33 ely reacts with AT-rich DNA sequences with a bent conformation; bizelesin also reacts with the minor

34 form a contiguous patch in the more severely bent conformation but become separated upon straightenin

35 Stabilization of the bent conformation by integrin transmembrane and cytoplas

36 ontaining a p53 binding site was locked in a bent conformation by ligating its ends to form a microci

37 after synthesis, and then beta3 assumes its bent conformation by virtue of its interaction with the

38 Bound acetylcholine adopts a bent conformation characterized with a quaternary ammoni

39 ression of alphavbeta3 locked in an inactive bent conformation conferred hantavirus infectivity of CH

40 that the domain is not straight but adopts a bent conformation (D-shaped) in the docked state of the

41 g the possibility that pro-alphaIIb adopts a bent conformation early in biogenesis.

42 approximately 175 degrees) and two distinct bent conformations (Fe-C-N angles <140 degrees).

43 TAP complexes were generated, which indicate bent conformation for peptides.

44 The S22W peptide adopts a bent conformation forming a hydrophobic pocket by hydrop

45 recycling factor and binds tRNA in a highly bent conformation in a hybrid peptidyl/exit site.

46 ) and the ligand-binding betaA domain of the bent conformation in regulating interaction of integrin

47 revealed not only that the IgEFc exists in a bent conformation in solution but also that the bend is

48 tent with alphaIIbbeta3 existing in variably bent conformations in equilibrium with each other on una

49 et in which substrates are bound in distinct bent conformations involving the Zn-binding site.

50 We show here that this same bent conformation is retained in the active site regardl

51 The bent conformation is sterically incompatable with the oc

52 The computed relative stability of bent conformations is sensitive to the ionic strength of

53 ta-tubulin dimers need to convert between a 'bent' conformation observed for free dimers in solution

54 Binding of DNA to hFEN1 in a bent conformation occurred independently of 5'-flap acco

55 ared with the crystal structure, including a bent conformation of the alpha4 relay helix and ordering

56 tes of myosin, corresponding to straight and bent conformations of the relay helix.

57 -binding protein, either stabilizes DNA in a bent conformation or induces a bend upon binding to give

58 c contraction at extremes where straight and bent conformations predominate, respectively.

59 The PBS domain adopts a bent conformation resembling the shape of a tRNA in apo

60 he MD simulations starting from an initially bent conformation resulted in the formation of a straigh

61 minus-strand DNA and the tRNA because of its bent conformation resulting in error-prone plus-strand D

62 e default state, likely corresponding to the bent conformation seen in the crystal structure of alpha

63 working model in which pro-alphaIIb adopts a bent conformation soon after synthesis, and then beta3 a

64 nced by solution x-ray scattering displaying bent conformations spanning 150 and 180 A for the mouse

65 conformation stabilized by origin DNA and a bent conformation stabilized by ssDNA.

66 egrin alpha and beta subunits stabilized the bent conformation strongly for alpha(X)beta(2) and less

67 at the ectodomain of alphaVbeta3 manifests a bent conformation that is capable of stably binding a ph

68 eg separation causes the integrin to adopt a bent conformation that is unable to respond to agonists

69 binds to both the wild-type and mutant in a bent conformation that orients the NO O atom toward the

70 nt models portray the inactive receptor in a bent conformation that upon activation converts to a ful

71 We conclude that HS displays bent conformations that are significantly distinct from

72 In an overall bent conformation, the intermediate affinity state of al

73 cognition mode by KIT, in which KIT adopts a bent conformation to facilitate each of its first three

74 We also observe cyanide binding in a bent conformation to Ni of the C-cluster, adjacent the s

75 dduct is six-coordinate with NO ligated in a bent conformation trans to the cysteinyl S, as evidenced

76 s and how alphaIIbbeta3 initially adopts the bent conformation, we mapped the conformational states o

77 the bound state, whereas THp-(1-43) adopts a bent conformation when free in solution, with higher con

78 itchblade-like" opening, from a low affinity bent conformation with a closed headpiece to an extended

79 nd that mutations that lock integrins in the bent conformation with disulfide bonds resist inside-out

80 -1 at different conformations, including the bent conformation with the lowest affinity.

81 ameshifting pseudoknots adopt characteristic bent conformations with stem 1 bending towards the major

82 with the IM-MS cross sections, indicate two "bent" conformations with the planes of the porphyrin and