ライフサイエンスコーパス: berberine

1 hydrochloride, 2-N-methylellipticinium, and berberine).

2 ically important alkaloids: magnoflorine and berberine.

3 o oxidized forms, including (RS)-canadine to berberine.

4 t was shown to be defective in the efflux of berberine, a model antimicrobial plant chemical.

5 Berberine, a natural product derived from a plant used i

6 The results showed that berberine administration at one time or before STZ-stimu

7 ed at clarifying the protective mechanism in berberine against islet cell apoptosis.

8 The first total synthesis of the dimeric berberine alkaloid ilicifoline (ilicifoline B) is report

9 Berberine alkaloids, which are cationic antimicrobials p

10 Berberine also reduced tumor-induced angiogenesis in vit

11 Berberine also suppressed the expression of NF-kappaB-re

12 Berberine, an isoquinoline alkaloid derived from a plant

13 Berberine, an isoquinoline alkaloid, is a traditional or

14 four-electron oxidations of (S)-canadine to berberine and (S)-tetrahydropapaverine to papaverine.

15 alone but strongly potentiated the action of berberine and other NorA substrates against S. aureus.

16 with small molecules, such as the alkaloids berberine and palmatine and the DNA intercalator ethidiu

17 the relative intensities of the bands due to berberine and palmatine suggest that the ancient paper i

18 resis/mass spectrometry (CE/MS) detection of berberine and palmatine using the microsprayer.

19 Putative triplex (BePI, coralyne, and berberine) and tetraplex [H(2)TmPyP, 5,10,15, 20-tetraki

20 orphine, the antimicrobials sanguinarine and berberine, and the vasodilator papaverine.

21 e bacterial resistance mechanism against the berberine antimicrobial.

22 cals," including resveratrol, quercetin, and berberine, are also AMPK activators.

23 Berberine (BBR) is a natural compound with variable phar

24 Increasing evidence demonstrates that berberine (BBR) is beneficial for obesity-associated non

25 Berberine (BBR) is known for its therapeutic effect on o

26 e plant-derived hypocholesterolemic compound berberine (BBR) up-regulates LDLR expression while down-

27 nt in the suppression of PCSK9 expression by berberine (BBR), a natural cholesterol-lowering compound

28 tures of BmrR bound to rhodamine 6G (R6G) or berberine (Ber) and cognate DNA.

29 Berberine binding promotes RXRalpha interaction with nuc

30 contain a large number of genes encoding for berberine bridge enzyme (BBE)-like enzymes.

31 l alcohol oxidase as reported previously for berberine bridge enzyme and other FAD-dependent oxidored

32 ium poppy stem transcriptome databases using berberine bridge enzyme yielded several candidate genes,

33 g of the pyrazinone ring by an FAD-dependent berberine bridge enzyme-like oxidoreductase has been pro

34 BLAST analysis identified the nec5 cDNA as a berberine bridge enzyme-like protein.

35 (S)-tetrahydroprotoberberine oxidase and the berberine bridge enzyme.

36 fies RXRalpha as a direct protein target for berberine but also dissects their binding mode and valid

37 associated with the antimetastatic effect of berberine by showing a nearly complete inhibition on inv

38 Of the non-flavonoid phytochemicals tested, berberine, celastrol, ellagic acid, limonin, oleanolic a

39 retinoid X receptor alpha (RXRalpha), where berberine concomitantly binding to and synergistically a

40 y determination of a 2 ng/microL solution of berberine contained as a dry residue in the bottom of a

41 aken together, these findings suggested that berberine could reduce metastasis and angiogenesis of ce

42 However, the berberine effect on pancreatic islets is still not clear

43 Furthermore, berberine enhances DNA methylation level in whole genome

44 ine into solution and consequently, quenched berberine fluorescence.

45 MDR-dependent efflux of ethidium bromide and berberine from S. aureus cells was completely inhibited

46 Berberine has several anti-inflammation and anticancer b

47 The most potent apoptosis was induced by berberine in ALL cells with both MDM2 overexpression and

48 The level of accumulation of berberine in the cells was increased strongly in the pre

49 ssects their binding mode and validates that berberine indeed suppresses beta-catenin signaling and c

50 Herein, we demonstrate that berberine induces apoptosis in acute lymphoblastic leuke

51 Berberine induces more apoptosis, cell cycle arrest, but

52 Here, we provide evidence that berberine inhibits beta-catenin function via directly bi

53 Moreover, berberine inhibits expressions of CAR and its target gen

54 of exonuclease I, leading to the release of berberine into solution and consequently, quenched berbe

55 sm of CAR metabolic pathway, suggesting that berberine is a promising candidate in anticancer adjuvan

56 Here we report that berberine is able to be cellular uptake and accessible t

57 Berberine is an ancient multipotent alkaloid drug which

58 Berberine is an isoquinoline alkaloid used for its pharm

59 Accordingly, berberine is protected in the G-quadruplex structure and

60 ynthesis of the biologically active alkaloid berberine is reported, and a versatile palladium-catalyz

61 aptamer (ATP-aptamer) and a DNA binding dye, berberine, is digested upon the addition of exonuclease

62 nd anti-inflammatory activities displayed by berberine may be mediated in part through the suppressio

63 ults indicated that the antiproliferation of berberine might be mediated by the unique epigenetic mod

64 that downregulation of MDM2 in ALL cells by berberine occurred at a posttranslational level through

65 mice to unravel the protective mechanism of berberine on islets.

66 ese processes, we investigated the effect of berberine on this pathway.

67 tion curves (2.5-100 pmol) for the standards berberine, palmatine, and hydrastinine spotted as a mixt

68 ch contains three major yellow chromophores: berberine, palmatine, and jatrorrhizine.

69 ntracellular target mediating the effects of berberine remains elusive.

70 Berberine reversed transforming growth factor-beta1-indu

71 menclature) could efflux xenobiotics such as berberine, rhodamine 123, and paraquat.

72 Our results suggest that berberine's anti-apoptotic effect on pancreatic primary

73 We investigated berberine's pharmacological activities from the perspect

74 ation and a subsequent upregulation of MDM2, berberine strongly induced persistent downregulation of

75 We found that berberine suppressed NF-kappaB activation induced by var

76 Furthermore, berberine suppresses the growth of human colon carcinoma

77 suggest that the ancient paper is richer in berberine than its modern counterpart.

78 beta-carboline harmine and the isoquinoline berberine, that ameliorated certain aspects of the DM1 p

79 ignificantly greater than that observed with berberine, the major constituent of the herb.

80 ovide the molecular basis for the ability of berberine to act as an anticancer and anti-inflammatory

81 binding mechanism of the anticancer alkaloid berberine to the human telomeric G4 (d[AG3(T2AG3)3]), co

82 el and tail vein injection model showed that berberine treatment reduced tumor growth and lung metast

83 The proapoptotic effects of berberine were closely associated with both the MDM2 exp

84 Several Berberis medicinal plants producing berberine were found also to synthesize an inhibitor of

85 as other naturally derived products, such as berberine, which is used in traditional medicine.

86 d by a SEM experiment showing the binding of berberine with one of the nucleoside derivatives, which