ライフサイエンスコーパス: beta-VLDL

1 lation of beta-very low density lipoprotein (beta-VLDL).

2 -/-) mice) internalized beta-migrating VLDL (beta-VLDL).

3 he LDL-receptor and none was able to degrade beta-VLDL.

4 l formation when the atherogenic stimulus is beta-VLDL.

5 ndent uptake of the apoE lipoprotein ligand, beta-VLDL.

6 urce or (b) independent actions of apoE3 and beta-VLDL.

7 ities by 35% and redistributing apoE2 to the beta-VLDL.

8 the same extent as excess unlabeled VLDL or beta-VLDL.

9 of ligand binding to LRP, and apoE-enriched beta-VLDL, a ligand for LRP, reduce PDGF-induced tyrosin

10 holesterol deposition during incubation with beta-VLDL alone, but completely blocked the augmented re

11 n in lipoproteins demonstrated a decrease in beta-VLDL and LDL cholesterol and an increase in HDL cho

12 ial effect was mediated by the apoE-enriched beta-VLDL and not by free apoE.

13 ns examined, Ac-LDL plus beta-VLDL, LDL plus beta-VLDL, and LDL plus Ac-LDL, was similar.

14 Furthermore, beta-VLDL antagonized the stimulatory effects of the end

15 nd beta-VLDL in coated pits, suggesting that beta-VLDL binding promoted the internalization of the LD

16 ibility, mutagenesis experiments showed that beta-VLDL binding was inhibited by mutations at D203 and

17 olesterol deposition in cells incubated with beta-VLDL, but not acetylated LDL.

18 an alter neurite outgrowth in the absence of beta-VLDL by constructing Neuro-2a cell lines expressing

19 ontaining beta-very low density lipoprotein (beta-VLDL) can stimulate neurite outgrowth to a signific

20 Moreover, M-CSF did not augment beta-VLDL cholesterol deposition in macrophages from LDL

21 Under these conditions, which allowed equal beta-VLDL-cholesteryl ester hydrolysis, cholesterol este

22 However, beta-VLDL clearance decreased due to decreased trapping

23 mechanism, while uptake of the VLDL remnant, beta-VLDL, does not.

24 LR-Y807C using LDLR-immunogold, LDL-gold and beta-VLDL-gold probes revealed enrichment of LDLR-Y807C-

25 ificantly greater extent than apoE4-enriched beta-VLDL in a central nervous system-derived neuronal c

26 obes revealed enrichment of LDLR-Y807C-bound beta-VLDL in coated pits, suggesting that beta-VLDL bind

27 asma apoE2 was predominantly associated with beta-VLDL in males and with HDL in females.

28 highest capacity in binding to apoE enriched beta-VLDL in vitro and was more effective in removing ap

29 lized cell system, energy repletion restored beta-VLDL-induced cholesterol esterification.

30 Energy depletion also inhibited beta-VLDL-induced, but not SMase-induced, cholesterol es

31 These treatments also inhibited beta-VLDL-induced, but not SMase-induced, cholesterol es

32 eta-migrating very low density lipoproteins (beta-VLDL) (intestinal and hepatic remnant lipoproteins)

33 ry low-density lipoprotein of beta mobility (beta-VLDL), it was with lower affinity and capacity than

34 studies we conclude that the binding of apoE-beta VLDL, lactoferrin, aprotinin, lipoprotein lipase, a

35 pairs of lipoproteins examined, Ac-LDL plus beta-VLDL, LDL plus beta-VLDL, and LDL plus Ac-LDL, was

36 E (apoE)-beta very low density lipoprotein (beta VLDL), lipoprotein lipase, aprotinin, lactoferrin,

37 mAb AC10 inhibited the binding of apoE-beta VLDL, lipoprotein lipase, aprotinin, and lactoferri

38 Pigeon beta-very-low-density lipoprotein (beta-VLDL), low-density lipoprotein (LDL), and acetylate

39 as rabbit beta-very low density lipoprotein (beta-VLDL), making it difficult to discern the biologica

40 The increase in LDL and beta-VLDL metabolism did not reflect a generalized effec

41 acellular domain (sLRPs) binds apoE-enriched beta-VLDL particles.

42 ion binding characteristics as apoE-enriched beta-VLDL particles.

43 ely required for recognition of both LDL and beta-VLDL particles.

44 beta-migrating very low-density lipoprotein (beta-VLDL) particles, which contain multiple copies of a

45 ntaining beta-very low density lipoproteins (beta-VLDL) possess similar cell binding and internalizat

46 eta-migrating very low density lipoproteins (beta-VLDL) stimulated cholesteryl [(3)H]oleate depositio

47 teins, or quantitation of 125I-apoE-enriched beta-VLDL, there was a 2-3-fold greater accumulation of

48 (73%) and triglycerides (89%) and converted beta-VLDL to pre-beta-migrating VLDL.

49 ed that the HIC(818) sequence is involved in beta-VLDL uptake by the LDLR-Y807C.

50 to the hLPL-expressing cells, whereas rabbit beta-VLDL was an effective competitor.

51 in the loss of surface LDLR-Y807C only when beta-VLDL was present.

52 oprotein, beta-very low density lipoprotein (beta-VLDL), was internalized by macrophages and hydrolyz

53 cholesterol (75%), triglycerides (117%), and beta-VLDL, while decreasing lipoprotein lipase and hepat

54 ion and degradation of (125)I-labeled LDL or beta-VLDL without altering the amount of lipoprotein bou