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1 glyceraldehyde-3-phosphate dehydrogenase and beta-glucosidase.
2 obiose, which can be converted to glucose by beta-glucosidase.
3 i = 8.2 nM) of the Thermotoga maritima TmGH1 beta-glucosidase.
4 es was evaluated with beta-galactosidase and beta-glucosidase.
5 ecific and multivalent interaction with acid beta-glucosidase.
6 n was found to be dependent on the bacterial beta-glucosidase.
7 elated with their activation effects on acid beta-glucosidase.
8 ort the identification of the H antigen as a beta-glucosidase.
9 nt activity of the lysosomal hydrolase, acid beta-glucosidase.
10 a for native and denatured broad specificity beta-glucosidase.
11 of the aglycones produced by hydrolysis with beta-glucosidase.
12 e of 4.55, as found for most of the fungi of beta-glucosidases.
13 transcription factors, ABC transporters, and beta-glucosidases.
14 glutamates that play catalytic roles in the beta-glucosidases.
15 ated sequence homology with genes for fungal beta-glucosidases.
16 ajor differences between these two cytosolic beta-glucosidases.
17 including endoglucanases, exoglucanases, and beta-glucosidases.
18 d to interpret the glucose dependence of GH1 beta-glucosidases.
19 n of the beetle myrosinase from other insect beta-glucosidases.
20 d has up to 76% sequence similarity to other beta-glucosidases.
21 ously for other glycoside hydrolase family 3 beta-glucosidases.
22 valently modify the nucleophile of retaining beta-glucosidases.
23 the salvage pathway involving, in part, acid beta-glucosidase 1 (GBA1), which cleaves glucosylceramid
24 the present study, we examined whether acid beta-glucosidase 1 (GBA1), which hydrolyzes glucosylcera
27 d and purified as follows: broad specificity beta-glucosidase 1460-fold and pyridoxine-beta-D-glucosi
36 sm to that determined at 37 degreesC for the beta-glucosidase (abg) from the mesophilic bacterium, Ag
37 ceramide; the same reaction catalyzed by the beta-glucosidase acid 1 (GBA1) defective in subjects wit
38 of 70.2-380.9 nM in various cancer cells by beta-glucosidase activation inside of the tumor cells, w
40 says revealed marked differences in secreted beta-glucosidase activities from three H. capsulatum res
48 8.3 and 17 muM, and also inhibited lysosomal beta-glucosidase activity in live cells at low-micromola
50 H. capsulatum culture supernatants revealed beta-glucosidase activity near the predicted mobility of
56 and one intracellular beta-glucosidase lacks beta-glucosidase activity, but efficiently induces cellu
57 beta-glucosidase enzymes (Delta3betaG) lacks beta-glucosidase activity, but efficiently induces cellu
58 data indicated that the null genotypes have beta-glucosidase activity, but the enzyme occurs as inso
59 f salicin and d-arabinose, and expression of beta-glucosidase activity, correctly assigned each strai
63 of detergent-independent membrane-associated beta-glucosidase activity; 3) was more variable among mo
65 ally interacts with a chimeric lectin called beta-glucosidase aggregating factor (BGAF), resulting in
70 protein, and BGAF is solely responsible for beta-glucosidase aggregation and insolubility and, thus,
71 neurodegenerative course had two novel acid beta-glucosidase alleles: a complex, maternally derived
72 GE by the endoplasmic reticulum and vacuolar beta-glucosidases allows the rapid formation of free ABA
74 ted against several glycosidases (alpha- and beta-glucosidase, alpha- and beta-galactosidase, alpha-
77 to compare the levels of phenolic compounds, beta-Glucosidase and antioxidant activity during the age
78 ehave as selective competitive inhibitors of beta-glucosidase and are promising candidates as pharmac
79 imental design to optimise the production of beta-glucosidase and convert glycosidic isoflavones in a
80 tural green olives is due to the activity of beta-glucosidase and esterase during the first months of
82 is a 35-kD protein and binds specifically to beta-glucosidase and renders it insoluble during extract
83 based on sequence differences between maize beta-glucosidase and sorghum beta-glucosidase (dhurrinas
84 howed 54 and 48% identities to raucaffricine beta-glucosidase and strictosidine beta-glucosidase, res
85 pe, and it specifically interacts with maize beta-glucosidases and forms large insoluble aggregates.
86 olved in forming a site for binding to maize beta-glucosidases and thus provides a plausible explanat
87 this study was to monitor olive hydrolytic (beta-glucosidase) and oxidative (peroxydase, POX, and po
88 al hydrolysis by a novel mammalian cytosolic beta-glucosidase, and (d) exert a weak antagonistic effe
89 Conduritol B epoxide is an inhibitor of acid beta-glucosidase, and lowers glucosylceramide degradatio
90 ars exhibited specificity for almond-derived beta-glucosidase, and the 1-nonylazetidine 25 inhibited
91 ineered strains express cellulase, xylanase, beta-glucosidase, and xylobiosidase enzymes under contro
95 to interact directly with the substrates in beta-glucosidases are not conserved in hydroxyisourate h
97 describes novel preparations of immobilized beta-glucosidase as highly stable and active catalysts f
98 The x-ray structure of N370S mutant acid beta-glucosidase at acidic and neutral pH values indicat
99 -deoxy-2-fluoro-beta-glucosides react with a beta-glucosidase at rates differing by 10(6)-fold, despi
101 gions to BGAF binding, we constructed mutant beta-glucosidases based on sequence differences between
103 -glucur) are both produced by E. coli, while beta-glucosidase (beta-gluco) is produced by Enterococcu
107 mnosperms) against the potential activity of beta-glucosidase (BG), N-acetyl-glucosaminidase (NAG), a
109 obacco (Nicotiana tabacum) plants expressing beta-glucosidase (Bgl-1) show modified development.
110 is end, we designed a chimeric cohesin-fused beta-glucosidase (BglA-CohII) that binds directly to the
113 in of BGAF is responsible for its lectin and beta-glucosidase binding and aggregating activities.
116 sists primarily of stereochemistry-retaining beta-glucosidases but also contains a subfamily of beta-
117 lucoside hydrolase but not broad specificity beta-glucosidase, but both were inhibited by the mechani
118 rabidopsis thaliana contain large amounts of beta-glucosidases, but the physiological functions of ER
120 dentify both catalytic residues of retaining beta-glucosidases by the combined use of cyclophellitol
121 l glucopyranoside hydrolysis by sweet almond beta-glucosidase can be generated based on 24 time-cours
122 ar enzymes of intact heterotrophic biofilms, beta-glucosidase (carbon-cycling) and l-leucin aminopept
124 ed it to non-homologous (putative) retaining beta-glucosidases categorized in GH1 and GH116: GBA2, GB
126 stine, spleen and kidney contain a cytosolic beta-glucosidase (CBG) that hydrolyses various beta-d-gl
127 which is encoded by an operon with a phospho-beta-glucosidase (CelA) and a cellobiose-specific sugar
128 i has been cloned, and the encoded 6-phospho-beta-glucosidase (cellobiose-6-phosphate [6P] hydrolase;
130 n mutant had increased expression of several beta-glucosidases, consistent with known inhibition of b
131 ization of both enzymes, as a membrane-bound beta-glucosidase could specifically digest soluble xylog
133 . Moench) has two isozymes of the cyanogenic beta-glucosidase dhurrinase: dhurrinase-1 (Dhr1) and dhu
134 s between maize beta-glucosidase and sorghum beta-glucosidase (dhurrinase 2, Dhr2), which does not bi
135 nd Gu2, to which BGAF binds, and the sorghum beta-glucosidase (dhurrinase) isozyme Dhr1, to which BGA
137 In certain maize genotypes, called "null," beta-glucosidase does not enter gels and therefore canno
139 d utilises the diglycosidase alpha-rhamnosyl-beta-glucosidase (EC 3.2.1.168) to quantitatively hydrol
141 ein from the native expression system showed beta-glucosidase enzymatic activity in substrate gels an
143 concentrations were associated with enhanced beta-glucosidase enzyme activities (V max ) but short-te
144 lasmid pMAD401 displayed increased levels of beta-glucosidase enzyme activity and H protein expressio
145 determine whether H. capsulatum contained a beta-glucosidase enzyme activity and whether this activi
146 nhibitors of glucocerebrosidase (GCase), the beta-glucosidase enzyme deficient in Gaucher disease (GD
147 enzymatic activities, results show that the beta-glucosidase enzyme is the key enzyme responsible fo
149 N. crassa mutant carrying deletions of three beta-glucosidase enzymes (Delta3betaG) lacks beta-glucos
150 re, a mutant lacking genes encoding both the beta-glucosidase enzymes and cellodextrin transporters (
151 eletions of two genes encoding extracellular beta-glucosidase enzymes and one intracellular beta-gluc
153 cells through the action of an intracellular beta-glucosidase following import by a high-affinity cel
156 hydrolysis of the sugar moiety by intestinal beta-glucosidases for uptake to the peripheral circulati
157 enzyme and the immobilised cells containing beta-glucosidase, for 2h at 40 degrees C, promoted effic
158 es were assayed to catalyze the process, and beta-glucosidase from Aspergillus niger was selected.
162 e alignment of the amino acid sequences of P-beta-glucosidase from Escherichia coli and F. mortiferum
163 gous expressed OeGLU, an oleuropein-specific beta-glucosidase from olive (Olea europaea), had enzymat
165 egions were fused to the bglC ORF encoding a beta-glucosidase from the thermophilic bacterium Thermob
166 different Arabidopsis (Arabidopsis thaliana) beta-glucosidases from glycoside hydrolase family 3.
167 Database searches revealed homology with beta-glucosidases from several sources (plant, bacteria,
168 validated the method by using the retaining beta-glucosidase GBA (CAZy glycosylhydrolase family GH30
171 beta-glucosidase GBA1 and the non-lysosomal beta-glucosidase GBA2 degrade glucosylceramide (GlcCer)
172 a-epoxide (CBE), as well as the nonlysosomal beta-glucosidase (GBA2) inhibitor N-butyldeoxygalactonoj
176 , is caused by insufficient activity of acid beta-glucosidase (GCase) and the resultant glucosylceram
180 del (CBE-N2a) was created by inhibiting acid beta-glucosidase (GCase) in N2a cells with conduritol B
183 somal sphingolipid degradation pathway, acid beta-glucosidase (GCase) requires saposin C for optimal
184 se is caused by mutations in the enzyme acid beta-glucosidase (GCase), the most common of which is th
187 tic patients with Gaucher disease (GD) (acid beta-glucosidase [Gcase] deficiency) are treated with in
188 ritance reported for the null alleles at the beta-glucosidase gene is actually for the BGAF protein,
190 order caused by deficiency in lysosomal acid beta-glucosidase (GlcCerase), the enzyme responsible for
193 addition of exogenous noncellulosomal enzyme beta-glucosidase; however, because the cellulosome is ad
195 Here we show that PYK10, the most abundant beta-glucosidase in A. thaliana root ER bodies, hydrolyz
196 acute increases in serum levels of cytosolic beta-glucosidase in animal models of liver injury may re
197 estigated which cell types express cytosolic beta-glucosidase in guinea pig liver, and characterized
198 tes by CCl4 resulted in release of cytosolic beta-glucosidase in parallel with the hepatocyte marker
199 estigate the possible role of a brush border beta-glucosidase in the hydrolysis of PNG, lactase phlor
200 e, and support the hypothesis that cytosolic beta-glucosidase in the liver functions to hydrolyze sma
204 poxide, a potent inhibitor of lysosomal acid beta-glucosidase, inhibited pyridoxine-beta-D-glucoside
205 propyl" analogue would be a potent retaining beta-glucosidase inhibitor for those enzymes reacting th
206 ophellitol aziridine-both covalent retaining beta-glucosidase inhibitors-we postulated that the corre
207 pectral changes indicated saposin C and acid beta-glucosidase interaction only in the presence of NCP
214 rufin beta-glucoside revealed that cytosolic beta-glucosidase is expressed in all hepatocytes, with n
217 lpha-galactosidase, and cellobiose-inducible beta-glucosidase is unaffected in the ccpA strain, sugge
218 onicus found that only one of four predicted beta-glucosidases is required in a physiological context
220 oside), whereas its close homolog, the maize beta-glucosidase isoenzyme Glu1, which shares 72% sequen
221 ave any effect on the binding of BGAF to the beta-glucosidase isozyme 1 (Glu1), and the BGAF-Glu1 com
222 y-1,4-benzoxaxin-3-one), whereas the sorghum beta-glucosidase isozyme Dhr1 (SbDhr1) hydrolyzes exclus
223 -1,4-benzoxazin-3-on e), whereas the sorghum beta-glucosidase isozyme Dhr1 hydrolyzes exclusively its
225 1-T29, E50-N127, and F466-A512) on the maize beta-glucosidase isozyme Glu1 are involved in interactio
227 enzymes by domain swapping between the maize beta-glucosidase isozymes Glu1 and Gu2, to which BGAF bi
229 r hydrological legacy alters the response of beta-glucosidase kinetics (i.e. type of inhibition) to s
230 ta-glucosidase enzymes and one intracellular beta-glucosidase lacks beta-glucosidase activity, but ef
231 mber of this family ( At3g06510; sfr2 ) is a beta -glucosidase-like gene that belongs to a distinct l
232 an M20b peptidase-like protein, and SLW3, a beta-glucosidase-like protein, in defense and the leaf-s
233 abolite repressor gene, cre-1, in the triple beta-glucosidase mutant resulted in a strain that produc
234 distinct subtypes result from different acid beta-glucosidase mutations encoding enzymes with absent
236 dicted protein sequence displays homology to beta-glucosidases of other organisms, but a recombinant
238 studies have also suggested that the 120-kDa beta-glucosidase participates in wall modification durin
239 st the insect but can be cleaved by a spruce beta-glucosidase, PgbetaGLU-1, which releases the active
240 tive surfaces with OM inputs had the highest beta-glucosidase, phosphatase, NAGase and cellobiohydrol
242 data support our hypothesis that the 120-kDa beta-glucosidase plays a morphogenetic role in the paras
243 The ability of olive endogenous enzymes beta-glucosidase, polyphenol oxidase (PPO) and peroxidas
245 astomic plants as a vehicle for heterologous beta-glucosidase production for the cellulosic ethanol i
247 nternal sequences obtained from the purified beta-glucosidase protein, and a motif resembling plant s
248 ucose, and benzaldehyde by the action of the beta-glucosidase prunasin hydrolase (PH) and mandeloniti
251 riodic infusions of macrophage-targeted acid beta-glucosidase reverse hepatosplenomegaly, hematologic
252 celery leaves was resistant to conversion by beta-glucosidase-rich ingredients, but was converted to
253 ther) derivatives are substrates for phospho-beta-glucosidase(s) belonging to Families 1 and 4 of the
254 munoblot analysis performed using maize-anti-beta-glucosidase sera detected two distinct dhurrinases
255 ich was confirmed by 3-fold inhibition using beta-glucosidase specific inhibitor [2,5-dihydroxymethy-
257 ctivity was visualized using the fluorescent beta-glucosidase substrate, resorufin beta-D-glucoside,
258 a two-component defense system comprising a beta-glucosidase that activates oleuropein into a toxic
259 iscovered was JMB19063, a novel three-domain beta-glucosidase that belongs to the GH3 (glycoside hydr
260 azinoid-specific UDP-glucosyltransferase and beta-glucosidase that catalyze the enzymatic functions r
263 we propose to redefine GBA2 activity as the beta-glucosidase that is sensitive to inhibition by N-bu
265 ,6-beta-glucanase, BT3312, and a periplasmic beta-glucosidase that targets primarily 1,6-beta-glucans
266 ibition by mechanism-based inhibitors of GH1 beta-glucosidases that utilize a double displacement ret
267 Compared with the broad specificity maize beta-glucosidase, this different binding mode explains t
269 e nutrients involves the action of 6-phospho-beta-glucosidase to convert them into usable monosacchar
271 e final enzymatic step uses laminarinase and beta-glucosidase to release the remaining beta-1,3-gluca
272 ide, and shown to be caused by the cytosolic beta-glucosidase using the inhibitors, conduritol beta-e
273 e (gluc78) encoding an antifungal glucan 1,3-beta-glucosidase was cloned from strain P1 of the biocon
275 the presence of active polyphenoloxidase and beta-glucosidase was determined by HPLC and UV-Visible s
276 The activity of pectin methyl esterase and beta-glucosidase was enhanced in ET-treated berry skins,
282 ubstrate specificity further, eight chimeric beta-glucosidases were constructed by replacing peptide
284 ism of substrate specificity further, mutant beta-glucosidases were generated by replacing Phe198, Ph
285 athepsin A (PPCA), neuraminidase (Neu1), and beta-glucosidase, were readily taken up and restored lys
286 rying mutation(s) in GBA, which encodes acid beta-glucosidase, were recruited at the SZMC Gaucher Cli
287 gh homology to several other reported fungal beta-glucosidases which are members of the family 3 glyc
288 this cluster shows high sequence homology to beta-glucosidases, which catalyze the hydrolysis of the
290 s niger is known to secrete large amounts of beta-glucosidases, which have a variety of biotechnologi
291 mino acid, membrane-associated lysosomal exo-beta-glucosidase whose defective activity leads to the G
292 glucose tolerance and stimulation of the GH1 beta-glucosidases will be crucial to improve their appli
293 owed highly specific inhibition of mammalian beta-glucosidase with a marked dependence of the potency
294 resulted in the thermo-stabilization of the beta-glucosidase with an increase in optimum temperature
296 e primary and tertiary structures of two GH1 beta-glucosidases with distinct glucose dependence, some
297 or allergic reactions and antibodies to acid beta-glucosidase within the first 6 months of treatment.
299 o the insoluble substrate only a fraction of beta-glucosidase would be available to the cellulosome.
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