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1 an Escherichia coli gene encoding the enzyme beta-glucuronidase).
2 cally modified enzyme was superior to native beta-glucuronidase.
3 vity and could label bystander proteins near beta-glucuronidase.
4 s activated by the oncologically significant beta-glucuronidase.
5 alcohol drug surrogates under the action of beta-glucuronidase.
6 ORF was replaced with that of marker protein beta-glucuronidase.
7 nd after treatment of the urine samples with beta-glucuronidase.
8 ith the lysosomal hydrolases cathepsin D and beta-glucuronidase.
9 8 of uidA, an E. coli-specific gene encoding beta-glucuronidase.
10 vity was based on a loop unique to bacterial beta-glucuronidases.
11 op" present in microbial, but not mammalian, beta-glucuronidases.
13 uction by strain B301D and reduced levels of beta-glucuronidase activities of the sypA::uidA and syrB
15 ne, gus and BG, have been reported to encode beta-glucuronidase activity among human colonic bacteria
16 -activated FITC-TrapG did not interfere with beta-glucuronidase activity and could label bystander pr
17 tissue-specific expression when analyzed by beta-glucuronidase activity assays, differences in gusA
18 as non-sorbitol fermenting and negative for beta-glucuronidase activity but serotyped O nontypeable:
19 ssing the BOS1-beta-glucuronidase transgene, beta-glucuronidase activity could be detected only after
22 w that the upstream sequence of POTH1 drives beta-glucuronidase activity in response to light and in
23 (Logan) of (18)F-FEAnGA also correlated with beta-glucuronidase activity in the same brain regions.
26 ted versions of the AtSUS2:promoter fused to Beta-glucuronidase activity revealed an internal 421 bp
27 carried only the BG gene gave relatively low beta-glucuronidase activity that was not induced by 4-ni
29 pment of near-IR (NIR) probes for imaging of beta-glucuronidase activity would be ideal to allow esti
30 ibition of root elongation, promotion of DR5-beta-glucuronidase activity, and reduction of Aux/IAA pr
31 oped two fluorescent probes for detection of beta-glucuronidase activity, one for the NIR range (cont
34 might be associated with elevated levels of beta-glucuronidase, an enzyme previously associated with
35 gene expression using northern and promoter-beta-glucuronidase analyses and found overlapping but di
36 criptome analysis are supported by promoter::beta-glucuronidase analyses of CHX genes and by other me
40 as the influence of carbohydrate quality on beta-glucuronidase and cancer activity, deserve further
41 ecimens were enzymatically deconjugated with beta-glucuronidase and extracted by a solid-phase extrac
42 he expression pattern of recombinant ProBTS::beta-GLUCURONIDASE and found that it is expressed in dev
43 tail by expressing in soybean roots promoter beta-glucuronidase and green fluorescent protein fusions
44 n promoter, when fused to the reporter genes beta-glucuronidase and green fluorescent protein, direct
45 is study sheds new light on the mechanism of beta-glucuronidase and helps to make industrial producti
46 rt inhibition can be mimicked by recombinant beta-glucuronidase and is associated with proteolytic de
48 ed by promoter and protein fusions using the beta-glucuronidase and the green fluorescent protein, re
49 d degranulation was 20-40% (myeloperoxidase, beta-glucuronidase) and 40-80% (lactoferrin) of maximal
50 curonidase, the auxin-sensitive reporter DR5:beta-glucuronidase, and auxin-dependent growth defects.
52 nidase without inhibiting purified mammalian beta-glucuronidase, and they do not impact the survival
53 Thus, by probing the actions of microbial beta-glucuronidases, and by understanding which substrat
54 were additionally hydrolysed enzymatically (beta-glucuronidase/arylsulphatase, cellulase), the compo
55 ve mutant (fls2) as the scion and ALMT1(pro):beta-glucuronidase as the rootstock revealed that both C
56 2AF35b in roots were revealed by a promoter::beta-glucuronidase assay, with atU2AF35b expressed stron
58 ntitative real time-PCR, GGPPS promoter-GUS (beta-glucuronidase) assays and publicly available microa
59 ydrolytic kinetics catalyzed by bovine liver beta-glucuronidase at interstitial pH = 7.4 fit the Mich
60 Using a whole-gene translational fusion to beta-glucuronidase, AtSUC9 expression was found in sink
65 ated that there is an increase in release of beta-glucuronidase by activated microglia into the extra
66 rthermore, selective disruption of bacterial beta-glucuronidases by small molecule inhibitors allevia
67 to ethanol while incubating our samples with beta-glucuronidase, confirming that the methyl protons o
68 lysis, expression analysis of a PLP promoter-beta-glucuronidase construct in transgenic plants and in
69 repress ABA induction of the HVA22 promoter-beta-glucuronidase construct, while OsWRKY72 and -77 syn
71 atography (HPLC) showed that the activity of beta-glucuronidase could be increased by 2.66-fold via t
73 hensive analysis of AAV1-treated brains from beta-glucuronidase-deficient mice (mucopolysaccharidosis
75 structure of one inhibitor bound to E. coli beta-glucuronidase demonstrates that it contacts and ord
76 validation study, coadministration with oral beta-glucuronidase derived from Escherichia coli and pre
77 zation of auxin redistribution using the DR5:beta-glucuronidase (DR5:GUS) auxin-responsive reporter s
81 glycosidase enzyme (beta-gly) and W492G in a beta-glucuronidase enzyme (beta-gluc), in which we engin
83 es have been conventionally studied by using beta-glucuronidase enzymes to release the phase I metabo
85 ly trapped on purified beta-glucuronidase or beta-glucuronidase-expressing CT26 cells (CT26/mbetaG) b
86 etaG) but not on bovine serum albumin or non-beta-glucuronidase-expressing CT26 cells used as control
88 y reverse transcription PCR, promoter-driven beta-glucuronidase expression in transgenic plants, and
93 and a delay in the asymmetric auxin-induced beta-glucuronidase expression with gravistimulation as c
94 ement of hydrogen peroxide-responsive AoPR10-beta-glucuronidase expression, suppression of plant stre
95 a heterologous in vivo Pv-ALF/phas-GUS (for beta-glucuronidase) expression system in transgenic Arab
96 (luciferase, green fluorescent protein, and beta-glucuronidase) facilitated in vivo profiling at the
98 preparations from different sources, such as beta-glucuronidase from Escherichia coli, were found to
102 t and under different light treatments using beta-glucuronidase fusion constructs with the promoters
105 of Arabidopsis plants containing the AtHD2C:beta-glucuronidase fusion gene revealed that AtHD2C was
106 s of Arabidopsis plants containing the HDA19:beta-glucuronidase fusion gene revealed that HDA19 was e
107 que NF-Y complexes, we have created promoter:beta-glucuronidase fusion lines for all 36 Arabidopsis g
108 wild-type and ABA response mutants, an ABI8-beta-glucuronidase fusion protein is localized primarily
110 ots by a promoter::green fluorescent protein-beta-glucuronidase fusion revealed strong gene expressio
111 sent at similar levels, and the two promoter-beta-glucuronidase fusion transgenes show very similar e
113 of both genes were investigated via promoter-beta-glucuronidase fusions and immunolocalization of a F
116 R1-GFP (green fluorescent protein) and NaKR1-beta-glucuronidase fusions driven by the native promoter
117 work, transgenic plants expressing ProRPL10:beta-glucuronidase fusions show that, while AtRPL10A and
118 Arabidopsis lines carrying AtWRKY30 promoter-beta-glucuronidase fusions showed transcriptional activi
119 resulting in increased activity of secreted beta-glucuronidase fusions that result from gene trap in
120 were independently validated using promoter:beta-glucuronidase fusions with the MtCRE1 CK receptor g
121 ression of each GGT in plants containing GGT:beta-glucuronidase fusions, the temporal and spatial pat
124 erobacteriaceae) and approximately 9% higher beta-glucuronidase gene abundance compared with nonrespo
125 e expression of two reporter constructs: the beta-glucuronidase gene driven by the GA-inducible Amy32
128 equired for the transgenic expression of the beta-glucuronidase gene fused to a synthetic auxin-induc
129 ta-Synthase-like1 (MtCBS1), using a promoter-beta-glucuronidase gene fusion, which revealed expressio
130 ox genes in Arabidopsis thaliana by promoter-beta-glucuronidase gene fusions and by quantitative RT-P
132 cally processed as predicted by bovine liver beta-glucuronidase, generating 2-aminoethylGdDO3A, 2.
133 on analyses using a complete set of promoter-beta-glucuronidase/green fluorescent protein reporter li
135 oral expression patterns as shown by DAO1pro:beta-glucuronidase (GUS) activity and DAO1pro:YFP-DAO1 s
136 sion of VHA-c1, monitored by promoter-driven beta-glucuronidase (GUS) activity was responsive to ligh
137 e gene and protein levels was analyzed using beta-glucuronidase (GUS) activity, quantitative reverse
138 dopsis lines were constructed expressing the beta-glucuronidase (GUS) and green fluorescence protein
139 e RT-PCR and transcriptional fusions to both beta-glucuronidase (GUS) and green fluorescent protein (
141 e kinetics of wild-type and in vitro evolved beta-glucuronidase (GUS) at the single molecule level.
143 e recently reported that PerT-GUS, a form of beta-glucuronidase (GUS) chemically modified to eliminat
147 In proof-of-principle experiments, a 35S::beta-glucuronidase (GUS) expression cassette was introdu
149 ion identified multiple lines that exhibited beta-glucuronidase (GUS) expression in the micropylar en
150 xpression patterns, as monitored by promoter-beta-glucuronidase (GUS) fusion and RT-PCR experiments.
155 agments of Ssp DnaE split intein and divided beta-glucuronidase (GUS) gene to encode GUS-n and GUS-c
158 a transgene with three direct repeats of the beta-glucuronidase (GUS) open reading frame (ORF) is ass
159 tive promoter and a coding region for either beta-glucuronidase (Gus) or glyphosate acetyltransferase
160 slated region (UTR) was used to drive either beta-glucuronidase (GUS) or green fluorescent protein (G
162 cyp71av1 promoter sequence was fused to the beta-glucuronidase (GUS) reporter gene and two varieties
163 lant system, we analyzed the activation of a beta-glucuronidase (GUS) reporter gene by enhancers cont
164 terium tumefaciens strain AGL1 harboring the beta-glucuronidase (GUS) reporter gene driven by the cau
166 nsformed with the RTE1 promoter fused to the beta-glucuronidase (GUS) reporter gene revealed that RTE
167 Gene and enhancer trap vectors carrying the beta-glucuronidase (GUS) reporter gene were inserted int
168 se regulator (ARR)5 gene promoter fused to a beta-glucuronidase (GUS) reporter gene, and cytokinin ox
169 , TAPNAC promoter elements were fused to the beta-glucuronidase (GUS) reporter gene, and spatial and
170 At3g25830 promoter activity, measured with a beta-glucuronidase (GUS) reporter gene, was primarily fo
173 s containing an INPACT cassette encoding the beta-glucuronidase (GUS) reporter had negligible backgro
174 -responsive Em promoter from wheat linked to beta-glucuronidase (GUS) to determine whether ABI3/VP1,
175 ansgenic Arabidopsis lines bearing promoter::Beta-glucuronidase (GUS) transcriptional fusions as well
177 have examined the differential expression of beta-glucuronidase (GUS) transgenes under the control of
178 of transgenic plants harboring an SOB5:SOB5-beta-glucuronidase (GUS) translational fusion under the
179 to direct the evolution of Escherichia coli beta-glucuronidase (GUS) variants with improved beta-gal
180 to direct the evolution of Escherichia coli beta-glucuronidase (GUS) variants with increased beta-ga
181 Expression of the reporter construct EBS: beta-glucuronidase (GUS) was detected in Arabidopsis roo
182 ncoded the minor activity, and ARGAH1-driven beta-glucuronidase (GUS) was expressed throughout the se
184 despite the fact that the uidA gene product, beta-glucuronidase (GUS), was produced only when the cel
188 r to infection with Agrobacterium carrying a beta-glucuronidase (GUS, uidA) gene with an artificial i
189 cco to regulate expression of uidA (encoding beta-glucuronidase; GUS) and the cytokinin-biosnythetic
190 ysosomal storage disease caused by deficient beta-glucuronidase (GUSB) activity resulting in defectiv
191 k cancer and Transferrin receptor (TFRC) and beta-Glucuronidase (GUSB) in pancreatic cancer were iden
193 evention of severe cardiac manifestations in beta-glucuronidase (GUSB) null mice BM-transplanted i.v.
194 approach, we identified the lysosomal enzyme beta-glucuronidase (GUSB), a member of a large family of
195 in's ability to ferment sorbitol and express beta-glucuronidase have complicated its detection and id
196 asured the distribution of recombinant human beta-glucuronidase (hGUS) and reduction in storage by we
197 vels were unchanged compared to control (DR5:beta-glucuronidase), however, in the seedlings expressin
198 auxin resistance, ectopically expressed DR5:beta-glucuronidase in developing embryos, and defective
200 Quin-C1 induces chemotaxis and secretion of beta-glucuronidase in peripheral blood neutrophils with
201 expected, incubation of these prodrugs with beta-glucuronidase in the culture medium led to much mor
203 nsin] and Thi1.2 [thionin]) or SA (PR1 [PR1a-beta-glucuronidase in tobacco]) signaling when both sign
204 y to express the reporter gusA gene encoding beta-glucuronidase in transgenic tobacco seeds relative
205 ase inhibitors that inhibit Escherichia coli beta-glucuronidase in vitro with Ki values between 180 n
206 moieties from drug metabolites by bacterial beta-glucuronidases in the GI lumen can significantly da
207 and structural basis of selective microbial beta-glucuronidase inhibition, which may improve human d
208 y effect of Klotho on NaPi-2a was blocked by beta-glucuronidase inhibitor but not by protease inhibit
211 cent protein fusion, beta-galactosidase, and beta-glucuronidase) into the F14.5L, J2R (encoding thymi
212 ossing of the abscission marker, Pro(PGAZAT):beta-glucuronidase, into the mutant reveals that while f
217 xpression of the auxin-induced reporter (DR5-beta-glucuronidase) is reduced in initiating lateral roo
218 ession patterns inferred from these promoter:beta-glucuronidase lines for roots, light- versus dark-g
220 vector-adapted vectors with three reporters, beta-glucuronidase, luciferase, and green fluorescent pr
221 n of the untranslated regions of StBEL5 to a beta-glucuronidase marker, translation in tobacco (Nicot
224 7 that are non-sorbitol fermenting (NSF) and beta-glucuronidase negative (GUD(-)) carry a large virul
225 t recent common ancestor of the contemporary beta-glucuronidase-negative, non-sorbitolfermenting STEC
226 TC-TrapG was selectively trapped on purified beta-glucuronidase or beta-glucuronidase-expressing CT26
227 monotherapy of necrotic tumors that liberate beta-glucuronidase or for antibody-directed enzyme prodr
229 nd temporal characterization, using Pro(HWS):beta-glucuronidase or Pro(HWS):green fluorescent protein
230 enerating stable transgenic lines expressing beta-glucuronidase plus (GUSplus), green fluorescent pro
231 EC) O55:H7 (sorbitol fermenting [SOR(+)] and beta-glucuronidase positive [GUD(+)]), through sequentia
236 and brain microvasculature, indicating that beta-glucuronidase reached brain parenchyma via the peri
238 e PET tracer (18)F-FEAnGA was able to detect beta-glucuronidase release during neuroinflammation in a
240 enic studies with an ABA-INSENSITIVE2 (ABI4)-beta-glucuronidase reporter construct revealed that in r
246 eaction analyses and promoter fusions to the beta-glucuronidase reporter gene confirmed the expressio
248 e ipx genes were variably induced in planta; beta-glucuronidase reporter gene expression analysis of
249 1 expression pattern, determined by promoter-beta-glucuronidase reporter gene expression, is associat
251 al analyses of WAKL promoters fused with the beta-glucuronidase reporter gene have shown that the exp
252 nslation start site direct expression of the beta-glucuronidase reporter gene primarily in the vascul
253 of the Ckx1 promoter to the Escherichia coli beta-glucuronidase reporter gene revealed that the gene
254 , expression of the RPT2 promoter fused to a beta-glucuronidase reporter gene shows differential expr
256 eased expression of the auxin-responsive DR5:beta-glucuronidase reporter gene, suggesting a perturbat
257 ying four copies of the GCC-box fused to the beta-glucuronidase reporter gene, we showed that the GCC
258 ce-specific manner and to transactivate ABRC-beta-glucuronidase reporter genes when introduced to bar
259 tested in C. reinhardtii chloroplasts using beta-glucuronidase reporter genes, and the nearly identi
260 -head oriented green fluorescent protein and beta-glucuronidase reporter genes, both transcripts and
261 OCALIZATION SIGNAL-GREEN FLUORESCENT PROTEIN/beta-GLUCURONIDASE reporter lines throughout the life cy
264 is of auxin influx facilitator expression in beta-glucuronidase reporter plants revealed that AUXIN R
265 In addition, primer extension analyses and a beta-glucuronidase reporter system were used to quantita
268 n pollen, as indicated from a promoter::GUS (beta-glucuronidase) reporter analysis and expression pro
269 that OsGZF1 can down-regulate a GluB-1-GUS (beta-glucuronidase) reporter and OsGZF1 was also able to
271 of POTH1 when fused to an expression marker beta-glucuronidase, repressed its translation in tobacco
272 hesis and biological evaluation of the first beta-glucuronidase-responsive albumin-binding prodrug de
273 ed by 2.66-fold via the addition of ISL to a beta-glucuronidase solution that contained GL at a 3:10
276 ptase-polymerase chain reaction and promoter:beta-glucuronidase studies indicate that all AtGT genes
278 evere diarrhea caused by symbiotic bacterial beta-glucuronidases that reactivate the drug in the gut.
279 localization of the provascular marker Athb8:beta-glucuronidase, the auxin-sensitive reporter DR5:bet
281 In transgenic plants expressing the BOS1-beta-glucuronidase transgene, beta-glucuronidase activit
284 Tissue-specific accumulation of an OBP3:OBP3-beta-glucuronidase translational fusion is regulated by
287 ' deletions, were fused to the reporter gene beta-glucuronidase (uidA) and analyzed in transgenic Nic
288 A herpes simplex virus type 2 (HSV-2) UL24 beta-glucuronidase (UL24-betagluc) insertion mutant was
289 in vivo functional assay using the reporter beta-glucuronidase under the auxin-inducible DR5 promote
290 ion, which can be rescued by expressing SUF4-beta-glucuronidase under the control of the SUF4 promote
291 -2 protoplasts inhibited nuclear import of a beta-glucuronidase-VirD2 nuclear localization signal fus
292 nteraction affinity for the lysosomal enzyme beta-glucuronidase was also much lower (K(d) = 54 microm
294 uman IGF-II fused to the C terminus of human beta-glucuronidase was taken up by MPS VII fibroblasts i
296 sitive for a vector-encoded secreted enzyme (beta-glucuronidase) was notably greater and more widespr
298 ociated with BC share an enzymatic activity, Beta-Glucuronidase, which may promote breast cancer.
299 usA2 and gusA3, were recovered that produced beta-glucuronidase with increased activity in neutral pH
300 All compounds are selective for E. coli beta-glucuronidase without inhibiting purified mammalian
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