ライフサイエンスコーパス: beta-hydroxylase

1 of norepinephrine from dopamine by dopamine beta-hydroxylase.

2 enteric ganglia by the promoter for dopamine beta-hydroxylase.

3 the N-terminal regulatory region of dopamine beta-hydroxylase.

4 , ceruloplasmin, lysyl oxidase, and dopamine beta-hydroxylase.

5 ive genes, tyrosine hydroxylase and dopamine beta-hydroxylase.

6 y for choline acetyltransferase and dopamine beta-hydroxylase.

7 ed against tyrosine hydroxylase and dopamine-beta-hydroxylase.

8 inactivating the gene that encodes dopamine beta-hydroxylase.

9 g enzymes, tyrosine hydroxylase and dopamine-beta-hydroxylase.

10 en as the human form of aspartyl(asparaginyl)beta-hydroxylase.

11 99 for aldosterone synthase compared with 11-beta-hydroxylase.

12 s, due to a disruption the gene for dopamine beta-hydroxylase.

13 nking water of metyrapone, which inhibits 11-beta-hydroxylase.

14 es a different mechanism than nonheme diiron beta-hydroxylases.

15 w expression there is enhanced GIBBERELLIN 3 BETA-HYDROXYLASE 1 (GA3ox1) expression, exhumed seeds ha

16 pressed in all Arabidopsis tissues analyzed, beta-hydroxylase 1 mRNA is always present at higher leve

17 ts in vivo that is structurally unrelated to beta-hydroxylase 1 or 2.

18 tical to the previously reported Arabidopsis beta-hydroxylase 1.

19 null mutant allele of LUT1, lut1-3, into the beta-hydroxylase 1/beta-hydroxylase 2 (b1 b2) double-mut

20 ivo, T-DNA knockout mutants corresponding to beta-hydroxylases 1 and 2 (b1 and b2, respectively) were

21 wo genes that encode beta-ring hydroxylases (beta-hydroxylases 1 and 2) have been identified in the A

22 of LUT1, lut1-3, into the beta-hydroxylase 1/beta-hydroxylase 2 (b1 b2) double-mutant background, in

23 nuclear antigen, and aspartyl-(asparaginyl)-beta-hydroxylase, a gene associated with increased cell

24 Aspartyl-(asparagyl)-beta-hydroxylase (AAH) is overexpressed in various malig

25 date compounds were tested for inhibition of beta-hydroxylase activity and selected for their capabil

26 ease in microsomal CYP3A dependent steroid 6 beta-hydroxylase activity but not in 90-day-old rats, po

27 Reduced beta-hydroxylase activity generated by the SMI MO-I-1100

28 AH protein in several tissues, lack aspartyl beta-hydroxylase activity in liver preparations, and exh

29 has been used successfully to assay aspartyl-beta-hydroxylase activity in microtiter plate format.

30 Beta-carotene hydroxylases (beta-hydroxylases) add hydroxyl groups to the beta-rings

31 Analyses of noradrenergic (dopamine-beta-hydroxylase) afferents revealed no differences in a

32 a cofactor to superoxide dismutase, dopamine-beta-hydroxylase, amyloid precursor protein, ceruloplasm

33 quent lipolysis, as do knockouts of dopamine beta-hydroxylase, an enzyme required for catecholamine s

34 he noradrenergic transmitter enzyme dopamine beta-hydroxylase and by using catecholamine histofluores

35 l complex that drives expression of dopamine-beta-hydroxylase and can also up-regulate expression of

36 density of axons immunoreactive for dopamine beta-hydroxylase and for serotonin.

37 coexist at significant levels with dopamine beta-hydroxylase and hence it is likely that this group

38 ubstances as well as for serotonin, dopamine-beta-hydroxylase and met-enkephalin are observed in the

39 ranule membrane proteins, including dopamine beta-hydroxylase and peptidyl glycine alpha-amidating en

40 al immunohistochemical detection of dopamine-beta-hydroxylase and PRV.

41 idence has shown that the genes for dopamine beta-hydroxylase and the dopamine transporter SLC6A3 may

42 catecholamine biosynthetic enzymes, dopamine beta-hydroxylase and tyrosine hydroxylase, regulation of

43 copic levels to investigate whether dopamine-beta-hydroxylase and tyrosine hydroxylase-containing axo

44 ect evidence for the termination of dopamine-beta-hydroxylase and tyrosine hydroxylase-positive fiber

45 adrenergic differentiation markers dopamine beta-hydroxylase and tyrosine hydroxylase.

46 -ir) axons in the PF also expressed dopamine-beta-hydroxylase and were therefore noradrenergic or adr

47 egion of homology in catalysis for Asp (Asn) beta-hydroxylase and, by analogy, other alpha-ketoglutar

48 t also sufficient to induce Phox2b+ dopamine-beta-hydroxylase+ and tyrosine hydroxylase+ NA neurons i

49 s most often affected are 21-hydroxylase, 11 beta-hydroxylase, and 3 beta-hydroxysteroid dehydrogenas

50 ile inhibitors of aminopeptidase A, dopamine beta-hydroxylase, and the intestinal Na(+)/H(+) exchange

51 ls expressing tyrosine hydroxylase, dopamine-beta-hydroxylase, and the SA lineage marker SA-1 in near

52 Dopamine-beta-hydroxylase- and tyrosine hydroxylase-positive fibe

53 chieved by intrathecal injection of dopamine beta-hydroxylase antibodies conjugated to the toxin sapo

54 sponse to psychological stress.Anti-dopamine-beta-hydroxylase antibody conjugated to the neurotoxin s

55 (spinal segments T2-T3) of an anti-dopamine-beta-hydroxylase antibody conjugated to the ribosomal to

56 In contrast, the use of an antidopamine beta-hydroxylase antiserum (which labels only adrenergic

57 AMP, protein complexes bound to the dopamine beta-hydroxylase AP1/cAMP response element element chang

58 mutant background, in which both Arabidopsis beta-hydroxylases are disrupted, yielded a genotype (lut

59 abolizing enzymes and revealed the taxane 10 beta-hydroxylase as a 1494-bp cDNA that encodes a 498-re

60 nce identity to the aforementioned taxane 10 beta-hydroxylase) as a taxane 13 alpha-hydroxylase by ch

61 Aspartyl-(asparaginyl)-beta-hydroxylase (ASPH) is a cell-surface enzyme that ge

62 Aspartate beta-hydroxylase (ASPH) is an enzyme overexpressed in hu

63 d DC population and load them with aspartate-beta-hydroxylase (ASPH), a highly expressed tumor-associ

64 ASPH encodes aspartyl/asparaginyl beta-hydroxylase (ASPH), which has been found to hydroxy

65 epsilon-ring hydroxylation but unrelated to beta-hydroxylases at the level of amino acid sequence.

66 Carotenoid beta-hydroxylases attach hydroxyl groups to the beta-ion

67 to PHA-L, tyrosine hydroxylase, and dopamine beta-hydroxylase, but not phenylethanolamine-N-methyltra

68 es, one of which was assigned as a taxane 10 beta-hydroxylase by functional expression in yeast.

69 Neither beta-hydroxylase cDNA maps to the LUT1 locus, and the ge

70 analysis of immunocytochemistry for dopamine beta-hydroxylase, choline acetyltransferase, and seroton

71 -injected rats pretreated with anti-dopamine-beta-hydroxylase conjugated to saporin to lesion hindbra

72 We have shown that an antibody to dopamine-beta-hydroxylase conjugated with saporin (anti-DBH-SAP)

73 R2)-mCherry (AAV2) into the RVLM of dopamine-beta-hydroxylase Cre transgenic mice (DbetaH(Cre/0)), mC

74 unilaterally into the brainstem of dopamine-beta-hydroxylase(Cre/0) mice.

75 for cortisol synthesis, including steroid 11 beta-hydroxylase (CYP11B1), and an enzyme that controls

76 Dopamine-beta-hydroxylase (D beta H) catalyzes the conversion of

77 ed to the antibody directed against dopamine beta hydroxylase (DbetaH-saporin), the analgesic and sed

78 out to investigate overlap between dopamine-beta-hydroxylase (DbetaH) -immunopositive projections an

79 rotein (pCREB) expressing nuclei in dopamine-beta-hydroxylase (DbetaH) containing cells in the LC.

80 nergic neurons were demonstrated by dopamine-beta-hydroxylase (DbetaH) immunofluorescence.

81 se in tyrosine-hydroxylase (TH) and dopamine beta-hydroxylase (DbetaH) immunoreactive (IR) axonal ter

82 Dopamine-beta-hydroxylase (DbetaH) is a copper-containing enzyme

83 et(MEN2B)) under the control of the dopamine-beta-hydroxylase (DbetaH) promoter develop profound neur

84 We used the human dopamine-beta-hydroxylase (DbetaH) promoter to direct transgenic

85 P) under the control of a synthetic dopamine-beta-hydroxylase (DbetaH) promoter was used to define ef

86 e catecholamine-synthesizing enzyme dopamine-beta-hydroxylase (DbetaH) was performed using confocal i

87 ral vectors into the brain of adult dopamine-beta-hydroxylase (DbetaH)(Cre/0) mice.

88 tions on tyrosine hydroxylase (TH), dopamine beta-hydroxylase (DbetaH), and the norepinephrine transp

89 in and tyrosine hydroxylase (TH) or dopamine beta-hydroxylase (DbetaH), respectively.

90 An antibody raised against DA-beta-hydroxylase (DbetaH), the mammalian enzyme that con

91 volved in catecholamine metabolism, dopamine beta-hydroxylase (DbetaH), which converts dopamine to no

92 Quantification of dopamine beta-hydroxylase (DbetaH)-immunostained varicosities was

93 er 2 (VMAT2), serotonin (5-HT), and dopamine-beta-hydroxylase (DbetaH; a marker for norepinephrine) i

94 enous tyrosine hydroxylase (TH) and dopamine-beta hydroxylase (DBH) gene expression in these cells.

95 ar tasks, ATP7A transfers copper to dopamine beta hydroxylase (DBH) within the lumen of the Golgi net

96 dramatically reduces expression of Dopamine Beta Hydroxylase (Dbh), a gene encoding a crucial catech

97 zed by immunoperoxidase labeling of dopamine beta hydroxylase (DbH), and gastric preautonomic PVN neu

98 hat express the NA synthetic enzyme dopamine beta hydroxylase (DbH)] in the caudal NST were lesioned

99 total phenotypic variance in plasma dopamine beta-hydroxylase (DBH) activity in samples from three di

100 were exposed to antibodies against dopamine beta-hydroxylase (DBH) and 5-HT.

101 esis, tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH) are absent.

102 Dopamine beta-hydroxylase (DBH) catalyzes the conversion of dopam

103 Dopamine beta-hydroxylase (DBH) catalyzes the production of norep

104 ly, immunohistochemical staining of dopamine-beta-hydroxylase (DBH) containing cells confirmed that s

105 norepinephrine (NE) deficiency (or dopamine beta-hydroxylase (DBH) deficiency) is a rare congenital

106 ormal tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH) expression in sympathetic neurons

107 To examine if Egr1 also regulates dopamine beta-hydroxylase (DBH) gene expression, PC12 cells were

108 The dopamine beta-hydroxylase (DBH) gene is expressed selectively in

109 gated by targeted disruption of the dopamine beta-hydroxylase (Dbh) gene, thereby eliminating these c

110 eated by targeted disruption of the dopamine beta-hydroxylase (DBH) gene.

111 in vitro by retrograde tracing and dopamine beta-hydroxylase (DBH) immunocytochemistry.

112 etic genes tyrosine hydroxylase and dopamine beta-hydroxylase (DBH) is regulated by cell type-specifi

113 Dopamine beta-hydroxylase (DBH) is the biosynthetic enzyme cataly

114 Dopamine-beta-hydroxylase (DBH) is the penultimate enzyme require

115 cy in an AD mouse model, we crossed dopamine beta-hydroxylase (DBH) knockout mice with amyloid precur

116 ously showed that ethanol regulates dopamine beta-hydroxylase (DBH) mRNA and protein levels in human

117 Tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH) mRNA expression in postmortem LC

118 Inhibition of dopamine beta-hydroxylase (DBH) results in a decrease in norepine

119 ymes, tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH) was examined.

120 targeted gene knockdown of NPY and dopamine-beta-hydroxylase (DBH), a catecholamine biosynthetic enz

121 immunocytochemical distribution of dopamine-beta-hydroxylase (DBH), a noradrenergic marker, in the b

122 In mice lacking dopamine beta-hydroxylase (DBH), an enzyme critical for NE synthe

123 active neurons was also labeled for dopamine-beta-hydroxylase (DBH), an enzyme involved in norepineph

124 e (VIP), tyrosine hydroxylase (TH), dopamine beta-hydroxylase (DBH), and muscarinic and alpha(1)- and

125 urotransmitter synthesizing enzyme, dopamine beta-hydroxylase (DBH), could selectively destroy centra

126 sses both the genes encoding TH and dopamine beta-hydroxylase (DBH), the key enzymes in norepinephrin

127 urons by inducing the expression of dopamine beta-hydroxylase (DBH), the terminal enzyme for noradren

128 ared the distribution and number of dopamine-beta-hydroxylase (DBH)- and phenylethanolamine-N-methylt

129 receptor population specifically in dopamine beta-hydroxylase (DBH)-expressing cells is both necessar

130 cystokinin (CCK) and noradrenergic, dopamine beta-hydroxylase (DBH)-expressing NTS neurons as two sep

131 the norepinephrine synthetic enzyme dopamine-beta-hydroxylase (DBH).

132 monooxygenase with low homology to dopamine beta-hydroxylase (DBH).

133 ic enzymes tyrosine hydroxylase and dopamine beta-hydroxylase (DBH).

134 the norepinephrine-synthetic enzyme dopamine beta-hydroxylase (DBH).

135 oreactive fibers did not co-contain dopamine beta-hydroxylase (DBH).

136 IP), tyrosine hydroxylase (TH), and dopamine-beta-hydroxylase (DBH).

137 ar sequence homologue of the enzyme dopamine beta-hydroxylase (DBH).

138 ase, tyrosine hydroxylase (TH), and dopamine beta-hydroxylase (DBH).

139 mice lacking NE due to mutation of dopamine beta-hydroxylase (dbh).

140 ic pathway that includes the enzyme dopamine-beta-hydroxylase (DBH).

141 ring the number and distribution of dopamine beta-hydroxylase (DBH)/cholinergic appositions, describe

142 Ethanol treatment elevated dopamine beta-hydroxylase (DBH, EC 1.14.17.1) mRNA and protein le

143 genetically by using mice that lack dopamine beta-hydroxylase (dbh-/- mice).

144 Gene-targeted mice that lack dopamine beta-hydroxylase (dbh-/-), the enzyme needed to convert

145 ucts (tyrosine hydroxylase, Th, and dopamine beta-hydroxylase, Dbh) are markedly altered.

146 tyrosine hydroxylase, Th) and Dbh (dopamine beta-hydroxylase, Dbh) mRNA, whereas several other SNS g

147 g patients with recently documented dopamine beta-hydroxylase deficiency at a single institution.

148 a finding has never been described in an 11 beta-hydroxylase deficient individual.

149 ested this hypothesis in vivo using dopamine beta-hydroxylase-deficient mice (DBH -/-), which are una

150 Dopamine beta-hydroxylase-deficient mice (Dbh-/-), lacking catech

151 n conjugated to an antibody against dopamine beta hydroxylase (DSAP) was microinjected bilaterally in

152 ble factor (HIF)-1 (FIH-1) is an asparaginyl beta-hydroxylase enzyme that was initially found to hydr

153 case of a 15-year-old male, deficient in 11 beta-hydroxylase enzyme, presenting with hypertensive ha

154 he evolutionarily related mammalian dopamine beta-hydroxylase enzyme.

155 b1 b2 double mutant, which lacks both known beta-hydroxylase enzymes, still contains significant lev

156 suggesting that a fourth unknown carotenoid beta-hydroxylase exists in vivo that is structurally unr

157 ied in our laboratory) in intron 8 of the 11-beta hydroxylase gene.

158 The mouse aspartyl beta-hydroxylase gene (Asph, BAH) has been cloned and ch

159 to the role of c-Fos in regulating dopamine beta-hydroxylase gene expression in response to cAMP, a

160 lanking -1012C --> T variant of the dopamine beta-hydroxylase gene was slightly increased and protect

161 e due to targeted disruption of the dopamine beta-hydroxylase gene, Dbh, were used to critically test

162 ne decarboxylase gene, tdc-1, and a tyramine beta-hydroxylase gene, tbh-1.

163 ivation of tyrosine hydroxylase and dopamine beta-hydroxylase genes after repeated episodes of stress

164 enomics-based approaches to isolate a second beta-hydroxylase genomic clone and its corresponding cDN

165 The human aspartyl (asparaginyl) beta-hydroxylase (HAAH) is a highly conserved enzyme tha

166 The S. typhimurium aspartyl/asparaginyl beta-hydroxylase homologue (designated lpxO) was cloned

167 In addition, dopamine-beta-hydroxylase immunohistochemistry, employed to deter

168 Previous studies have demonstrated dopamine-beta-hydroxylase immunoreactive (DBH-ir) fibers in the N

169 15 dorsal group and the very sparse dopamine-beta-hydroxylase immunoreactive fibers and varicosities

170 yrosine hydroxylase fibers, and not dopamine-beta-hydroxylase immunoreactive fibers, were located thr

171 No dopamine-beta-hydroxylase immunoreactive perikarya were observed

172 ty of tyrosine hydroxylase- but not dopamine-beta-hydroxylase-immunoreactive axons in sensory, motor,

173 Both tyrosine hydroxylase- and dopamine-beta-hydroxylase-immunoreactive fibers and punctate vari

174 Dopamine beta-hydroxylase-immunoreactive sympathetic nerves inner

175 sine hydroxylase-immunoreactive and dopamine-beta-hydroxylase-immunoreactive) were also quantified in

176 tyrosine hydroxylase perikarya, but dopamine-beta-hydroxylase immunoreactivity was very sparse within

177 activities of monoamine oxidase and dopamine beta hydroxylase in the hippocampus and prefrontal corte

178 ses to male song and the density of dopamine-beta-hydroxylase in area X and another song nucleus LMAN

179 axons immunoreactive for the enzyme dopamine-beta-hydroxylase in representative areas of acutely and

180 adrenaline (NA) and NA-synthesizing dopamine beta-hydroxylase in the peripheral nervous system.

181 similarity to mammalian aspartyl/asparaginyl beta-hydroxylases in bacteria known to make 2-hydroxyacy

182 hree homeologs), HYD1 and HYD2, which encode beta-hydroxylases in wheat.

183 nt the entire complement of non-heme di-iron beta-hydroxylases in wheat.

184 ese neurons were immunopositive for dopamine beta-hydroxylase, indicating that they were catecholamin

185 production was blocked by metyrapone, an 11-beta-hydroxylase inhibitor, females exhibited reduced se

186 howed previously that the selective dopamine beta-hydroxylase inhibitor, nepicastat, had no effect on

187 e examined tyrosine hydroxylase and dopamine-beta-hydroxylase innervation in hormonally intact adult

188 NPY knock-out (NPY KO) and dopamine beta-hydroxylase knock-out (DBH KO) mice that lack NE ar

189 Here, we exposed dopamine beta-hydroxylase knock-out (Dbh(-/-)) mice, which lack N

190 telemetrically monitoring the Tb of dopamine beta-hydroxylase knock-out (Dbh-/-) mice, which lack the

191 ethanol-mediated behaviors by using dopamine beta-hydroxylase knockout (Dbh -/-) mice that specifical

192 Additionally, dopamine beta-hydroxylase knockout (Dbh(-)(/)(-)) mice that do no

193 sts and examining motor deficits in dopamine beta-hydroxylase knockout (Dbh-/-) mice that lack NE alt

194 imulant responses by testing LRA in dopamine beta-hydroxylase knockout (Dbh-/-) mice that lack NE.

195 sverse aortic constriction (TAC) in dopamine beta-hydroxylase knockout mice (Dbh(-/-), genetically al

196 reatment with NE inhibitors, and in dopamine beta-hydroxylase knockout mice (which cannot synthesize

197 enomic region harbors monooxygenase dopamine beta-hydroxylase-like 1 gene (MOXD1), implicated in the

198 In a separate study, TH-ir and dopamine-beta-hydroxylase-like immunoreactivity (DBH-ir) were map

199 tro, and cAMP- and Phox2a-dependent dopamine-beta-hydroxylase-luciferase reporter expression.

200 Dopamine beta-hydroxylase (-/-) mice are unable to synthesize NA

201 usceptibility was determined in the dopamine beta-hydroxylase null mutant (Dbh -/-) mouse using four

202 nce Raman spectroscopies show that CmlA, the beta-hydroxylase of the chloramphenicol biosynthetic pat

203 in, saporin-conjugated antiserum to dopamine-beta-hydroxylase, on acute restraint stress-induced acti

204 to investigate the distribution of dopamine-beta-hydroxylase- or tyrosine-hydroxylase-labeled extran

205 hydroxylase, L-dopa decarboxylase, dopamine beta-hydroxylase, phenylethanolamine-N-methyltransferase

206 strate PHA-L, tyrosine hydroxylase, dopamine beta-hydroxylase, phenylethanolamine-N-methyltransferase

207 em sections were stained for c-Fos, dopamine beta-hydroxylase, phenylethanolamine-N-methyltransferase

208 rosine hydroxylase-positive but not dopamine-beta-hydroxylase-positive fibers, suggesting dopaminergi

209 s were in close proximity to single dopamine-beta-hydroxylase-positive varicosities, others, particul

210 verexpress the galanin gene under a dopamine-beta-hydroxylase promoter (GalOE).

211 its cAMP-mediated expression of the dopamine beta-hydroxylase promoter construct in PC12 and CATH.a c

212 egulation of transcription from the dopamine beta-hydroxylase promoter is mediated by the AP1 protein

213 nsgenic mice were created using the dopamine beta-hydroxylase promoter to direct expression of RET(ME

214 converge on a single element in the dopamine beta-hydroxylase promoter to elicit activation of gene e

215 ss galanin under the control of the dopamine beta-hydroxylase promoter to study the neurochemical and

216 H-Ras in transgenic mice using the dopamine-beta-hydroxylase promoter, which directs expression to t

217 tant under the control of the human dopamine beta-hydroxylase promoter.

218 onatal lethality by expression of a dopamine beta-hydroxylase promoter/ET(B) receptor transgene (Tg/T

219 rescent protein under an artificial dopamine beta-hydroxylase (PRSx8) promoter to trace the spinal pr

220 emporal expression of TH, 5-HT, and dopamine beta hydroxylase reactivity, we determined that these fi

221 The 10 beta-hydroxylase represents the initial cytochrome P450

222 Immunostaining for dopamine beta-hydroxylase revealed fibers within dopamine (DA) ne

223 pecifically lesioning them with antidopamine beta-hydroxylase-saporin (DBH-SAP) injected via the 4th

224 roventricularly with saline or anti-dopamine-beta-hydroxylase-saporin, a toxin that destroys noradren

225 Intracerebroventricular anti-dopamine beta-hydroxylase/saporin, a treatment that destroys a ma

226 y endocytosis assessed by measuring dopamine-beta-hydroxylase (secretory granule membrane) internaliz

227 By contrast, GA4, which encodes 3 beta-hydroxylase, showed low expression in stems and its

228 beta-Hydroxylase single mutants do not exhibit obvious g

229 ic enzymes tyrosine hydroxylase and dopamine beta-hydroxylase, suggesting a role for ARIX in expressi

230 r tyrosine hydroxylase, but not for dopamine-beta-hydroxylase, suggesting that these axonal arrays ar

231 We found that levels of tyramine beta-hydroxylase (TbetaH), an essential enzyme for the b

232 la melanogaster gene, which encodes tyramine beta-hydroxylase (TBH), the enzyme that catalyzes the la

233 s, tyrosine decarboxylase (TDC) and tyramine beta-hydroxylase (TBH).

234 al residues in bovine aspartyl (asparaginyl) beta-hydroxylase that are located in a region of homolog

235 In contrast to the well studied beta-hydroxylases that have been cloned and characterize

236 ocalization of immunoreactivity for dopamine beta-hydroxylase (the synthetic enzyme for noradrenaline

237 ed mice lacking the gene coding for dopamine beta-hydroxylase, the enzyme responsible for synthesis o

238 ipts encoding NET, NET protein, and dopamine beta-hydroxylase; these neurons lack tyrosine hydroxylas

239 convert tyrosine into tyramine and tyramine beta-hydroxylase to convert tyramine into octopamine.

240 pared with tyrosine hydroxylase and dopamine beta-hydroxylase, to reflect the extent of adrenergic co

241 ies indicating direct activation of dopamine beta-hydroxylase transcription by Phox2a/2b, the present

242 ulation of tyrosine hydroxylase and dopamine beta-hydroxylase transcription was confirmed in PC12 cel

243 NE and dopamine beta-hydroxylase were increased by 3.8- and 10.7-fold, r

244 st 5-HT and the NA precursor enzyme dopamine beta-hydroxylase were utilized to examine the density of

245 closely related invertebrate enzyme tyramine-beta-hydroxylase, which converts tyramine to OA, suggest

246 noradrenergic biosynthetic enzyme, dopamine beta-hydroxylase, which is instead regulated by Ascl1.