ライフサイエンスコーパス: beta-ketoacyl-ACP synthase

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1 ferase activity (electrophile charging), and beta-ketoacyl ACP synthase activity (condensation).

2 terial cell growth through inhibition of the beta-ketoacyl-ACP synthase activity of type II fatty aci

3 iosynthesis, pfKASIII exhibited typical KAS (beta-ketoacyl ACP synthase) activity using acetyl-CoA as

4 al production, with fatty-acid biosynthesis (beta-ketoacyl-ACP synthases) attracting the most attenti

5 beta-Ketoacyl-ACP synthases catalyze the condensation st

6 teins: an acyl carrier protein (ACP) and two beta-ketoacyl ACP synthase components known as KSalpha a

7 contribution to chain length regulation of a beta-ketoacyl-ACP synthase, Cw KAS A1, derived from Cuph

8 This enzyme, along with the M. tuberculosis beta-ketoacyl ACP synthase I mtKasA, catalyzes the Clais

9 by FabA was only detected in the presence of beta-ketoacyl-ACP synthase I (FabB).

10 ne by regulating the expression of the fabB (beta-ketoacyl-ACP synthase I) and fabA (beta-hydroxydeca

11 petition for 16:0-ACP by down-regulating the beta-ketoacyl-ACP synthase II 16:0 elongase further incr

12 se), acpP (encoding ACP), and fabF (encoding beta-ketoacyl-ACP synthase II) genes was cloned and sequ

13 e residues in Streptococcus pneumoniae FabF (beta-ketoacyl-ACP synthase II; SpFabF) were investigated

14 tified initiation of fatty acid synthesis by beta-ketoacyl-ACP synthase III (fabH) and enoyl-ACP redu

15 ructure of ACP with the crystal structure of beta-ketoacyl-ACP synthase III (FabH) and experimentally

16 at the inhibition of chain initiation at the beta-ketoacyl-ACP synthase III step contributes to the a

17 The fabH gene (encoding beta-ketoacyl-ACP synthase III), which in most gram-nega

18 eins: ACP (acyl carrier protein) and KASIII (beta-ketoacyl-ACP synthase III).

19 FabH, beta-ketoacyl-ACP synthase III, is a particularly attrac

20 c deletion of acyl carrier protein (ACP) and beta-ketoacyl-ACP synthase indicated that this pathway i

21 etreatment of the wild-type protein with the beta-ketoacyl-ACP synthase inhibitor cerulenin also bloc

22 racterization of purified KasA and KasB, two beta-ketoacyl-ACP synthase (KAS) enzymes of the M. tuber

23 beta-Ketoacyl-ACP synthases (KAS) are key enzymes involv

24 encoding beta-ketoacyl-acyl carrier protein (beta-ketoacyl-ACP) synthase (KAS) III (FabH), was overex

25 carrier protein (ACP) reductase, InhA, and a beta-ketoacyl-ACP synthase, KasA.

26 The acyl-carrier protein (ACP), beta-ketoacyl-ACP synthase (KS) and acyltransferase (AT)

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