ライフサイエンスコーパス: beta-strand

1 tor's binding loop (encompassing the contact beta-strand).

2 1) included in a "kink" followed by an extra beta strand.

3 helix, echoing the role of ugi's inhibitory beta strand.

4 resulting in a shortening of the C-terminal beta-strand.

5 tein in the crystal lattice to form an extra beta-strand.

6 a disordered solvent-exposed amino-terminal beta-strand.

7 acting in an antiparallel fashion with a PDZ beta-strand.

8 main arrangements, connected by a continuous beta-strand.

9 posed of domains formed by alpha helices and beta strands.

10 led the LytTR domain, which mainly comprises beta strands.

11 he parallel/antiparallel organization of the beta strands.

12 the orientation of residues in transmembrane beta-strands.

13 of only approximately 4.8 A between stacked beta-strands.

14 r by packing of their hydrophobic C-terminal beta-strands.

15 rils differ in intermolecular arrangement of beta-strands.

16 ace of hbeta2m containing the A, B, E, and D beta-strands.

17 consistent with the behavior of amphipathic beta-strands.

18 ty and two D-lysines to limit the lengths of beta-strands.

19 n partially solved and are made up mainly of beta-strands.

20 f intrinsically disordered domains (IDDs) or beta-strands.

21 urns, helices, and antiparallel and parallel beta-strands.

22 es that are, in the fibrillar state, part of beta-strands.

23 that form H-bonds across the dimer interface beta-strands.

24 vent-exposed N terminus spanning the A and B beta-strands.

25 nied with a long-range order of well-defined beta-strands.

26 boxylated agarose use a scaffold of unpaired beta-strands.

27 the peptide hydrogen bonded between parallel beta-strands.

28 n-like shape composed of mostly antiparallel beta-strands.

29 31 and 157, which increased the formation of beta-strands.

30 These results suggest that beta-strands 1 and 12 contribute antagonistically to act

31 Glu-79 and Glu-416 are located in beta-strands 1 and 12, respectively.

32 In the other orientation, beta-strands 1-3 and helix 2 on the opposite face of the

33 We identified substitutions in beta-strand-1 and C-terminal residues of yeast Rps5 that

34 Consistently, the beta-strand-1 substitution greatly destabilized the 'PIN

35 Here, stemming from beta-strand 10 of the binding domain, the invariant alph

36 ation properties of split proteins involving beta-strands 10 and 11.

37 with both host proteins interacting with Vif beta-strand 2.

38 the cavity located between alpha-helix D and beta-strand 2A.

39 Ser(P)(279)to interact with the back face of beta-strand 3 (Tyr(286)is on the front face) and loop 2,

40 t coordination of Ser(P)(282)with the end of beta-strand 3 enables Ser(P)(279)to interact with the ba

41 putative dockerin-binding site, centered at beta-strands 3, 5, and 6, is likely to be conserved in o

42 differences are found mainly in the dynamic beta strands 4, 5, and 7, triggered by partial protonati

43 local conformational changes in helix 2 and beta-strand 4, both of which are compromised to maintain

44 The Phe65-Phe71 pair spans beta-strands 4 and 5 in the beta-barrel, which lack inte

45 ng the N-terminal tail and a loop connecting beta-strands 4 and 5, consistent with interactions invol

46 lices 3 and 7 and the degree of structure in beta-strand 5.

47 red to as HPR motif) is also present between beta-strands 5 and 6 of TILs.

48 SAM-binding fold but the region linking core beta strands 6 and 7 (the 'beta6/7 linker') has a unique

49 RD not involved in carbohydrate recognition (beta-strands 7-9; residues approximately 200-220), formi

50 constrained into either a 310-helix (1-6) or beta-strand (7-9) conformation, with variable numbers of

51 Leu-375-Pro-380 of TolA, which constitutes a beta-strand addition commonly seen in more promiscuous p

52 modules more C-terminal than (3)FNIII limit beta-strand addition to (1-5)FNI within intact soluble F

53 8-9)FNI, demonstrated that binding occurs by beta-strand addition.

54 t beta-barrel made up of seven anti-parallel beta-strands along with two surrounding alpha-helices.

55 domain that interact with PCSK9, notably the beta-strand and a discontinuous short alpha-helix, and i

56 the linker connecting the helix to the first beta-strand and adjacent barrel residues.

57 RsmF deviates from the canonical 5 beta-strand and carboxyl-terminal alpha-helix topology o

58 racy, with a blind three-state (alpha-helix, beta-strand and coil) secondary structure prediction acc

59 tructure, which includes the relocation of a beta-strand and repositioning of the functionally import

60 e [KIGAKI](3) was designed as an amphiphilic beta-strand and serves as a model for beta-sheet aggrega

61 lyroll domain B was inserted between the 7th beta-strand and the 7th alpha-helix of the catalytic dom

62 structure, which is formed by regular (i.e. beta-strands and alpha-helices) and non-periodic structu

63 hains of nonpolar residues stemming from the beta-strands and alpha-helices.

64 beta-barrel containing 19 membrane spanning beta-strands and an N-terminal alpha-helical region.

65 lt a 1 is a unique beta-barrel comprising 11 beta-strands and forms a "butterfly-like" dimer linked b

66 ng advantage of self-sorting between peptide beta-strands and hydrocarbon chains, we have demonstrate

67 e with alpha-helical domains on one side and beta-strands and loops on the other.

68 bular domain structure, consisting mostly of beta-strands and random coil with two small alpha-helice

69 eric medin comprising a stable core of three beta-strands and shorter more labile strands at the term

70 terfaces, one involving interactions of ABED beta-strands and the other involving GFCC'C'' beta-stran

71 structure, formed from an elongated stack of beta-strands, and have a rigidity similar to that of sil

72 version of the alpha-helical coiled coils to beta-strands, and partial unfolding of the protein, may

73 ed beta-barrel fold with mostly antiparallel beta-strands, and the loops extending out the beta-barre

74 acking interactions by which the constituent beta-strands are assembled hierarchically into protofila

75 ogen-bonded dimers are antiparallel, and the beta-strands are fully aligned, with residues 17-23 of o

76 e chemical shift assignments indicate that 4 beta-strands are present in the fibril's secondary struc

77 topological changes during fusion using the beta-strand as the fusogenic conformation.

78 can be achieved to atomic-level accuracy by beta-strand assembly or through metal-mediated interacti

79 ha-helices and pervasively in the underlying beta-strands associated with a pair of large clusters of

80 drogen-bonded residue pairs between adjacent beta-strands at an accuracy of approximately 70%.

81 B24) to a 60 degrees rotation of the B25-B28 beta-strand away from the hormone core to lie antiparall

82 able structures of VDAC proteins show a wide beta-stranded barrel pore, with its N-terminal alpha-hel

83 transfer structural motifs range from multi-beta-strand barrels, to beta-sheet cups and baskets cove

84 glutamine-based aggregates contain identical beta-strand-based cores.

85 led the external loop connecting the B and C beta-strands (BC loop) of the capsid protein VP1 (residu

86 cF) consists of an N-terminal domain of four beta-strands (beta1-beta4) connected by four alpha-helic

87 boxylate side chain at the tip of the second beta-strand (beta2-Asp/Glu).

88 However, mutations in beta strands beta5 and beta6 do not perturb G protein ac

89 ded alpha-helix II and hairpin turns between beta-strands betaC-betaD and betaE-betaF as well as seve

90 featuring reciprocal exchange of N-terminal beta-strands between two protomers.

91 84, Cys88, and Cys91 located after the first beta-strand bind a [4Fe-4S] cluster.

92 s of topologically equivalent water-mediated beta-strand bridging interactions within the pseudosymme

93 e finding, because the formation of extended beta-strands by monomeric Abeta proteins suggests a plau

94 dual substrate specificity within the seven beta-strand class of lysine-specific methyltransferases,

95 hese results give insight into split protein beta-strand complementation and enhance a distinct appro

96 By contrast, nine beta-strands comprise the fibrils formed from DeltaN6, i

97 ions, which contrasted dramatically with the beta strand conformation previously observed with a broa

98 ich the ligand main chain adopts an extended beta-strand conformation by interacting in an antiparall

99 ates that approximately 70 residues are in a beta-strand conformation in the fibril core.

100 The ability of the beta-strand conformation of the fusion peptide to genera

101 , which revealed that each molecule adopts a beta-strand conformation that stack together to form par

102 ture reveals that the peptide approximates a beta-strand conformation whose helical symmetry matches

103 due segment termed the stalk, which adopts a beta-strand conformation, instead of forming an alpha-he

104 branes, the TMD changes significantly to the beta-strand conformation.

105 and PHF6 hexapeptide motifs, the latter in a beta-strand conformation.

106 V1V2 antigens, suggesting recognition of the beta-strand conformation.

107 ions, our experiments show that the extended beta-strand conformational state of PHF6((*)) is readily

108 ch repeat domain of PP32 is composed of five beta-strand-containing repeats anchored by terminal caps

109 -41, directly control the differences in the beta-strand content found between the Abeta40 and Abeta4

110 ic and tetrameric oligomers that are rich in beta-strand content.

111 t that random or out-of-phase motions of the beta-strands contribute greater than two-thirds of the i

112 teinase-assisted removal of their N-terminal beta strand, creating an extended hydrophobic groove tha

113 amyloidogenic conditions (pH6.4-3.7), where beta-strand D and regions of the D-E and E-F loops were

114 of the residues in the beta-sheet containing beta-strands D, A, G, and H undergo conformational fluct

115 ues from the N terminus, 40s turn, and third beta-strand (defined as beta-domain) is novel.

116 structure or changing from alpha helical to beta strand depending on the solvents and molecules adde

117 tion of hairpins connecting two antiparallel beta-strands determines overall folding.

118 Here we show that alpha helices and beta strands differ significantly in their ability to to

119 that rupture and re-insertion of individual beta-strands do not take place locally but require the S

120 two Ig-like domains followed by an elongated beta-stranded domain with a new fold.

121 its N-terminal alpha-helical and C-terminal beta-strand domains, respectively.

122 bilized by a core domain assembled from four beta strands donated by one VipA and two VipB molecules.

123 gh backbone-to-backbone interactions at open beta-strand edges, in a manner that resembles the inter-

124 ntiparallel arrangement of alpha-helices and beta-strands, enumerated all possible topologies formed

125 ive strategies for mimicking alpha-helix and beta-strand epitopes have been developed, producing valu

126 of another 10FNIII domain via a Trp-mediated beta-strand exchange to stabilize a partially unfolded i

127 heet segments and the turn linking these two beta-strands exhibit high order parameters between 0.8 a

128 he other beta-sheet are limited to the outer beta-strand F, which packs against strand F' in the tetr

129 Here we identify beta-strands F and H as necessary for TTR aggregation.

130 ve substrates, which harbor mutations within beta-strands, fail to associate productively with the Ba

131 3 residues of the ATG3 fragment form a short beta-strand followed by an alpha-helix on a surface area

132 ty of amyloidogenic peptides to convert into beta-strands for their polymerization into amyloid fibri

133 the Protein Data Bank where alpha-helices or beta-strands form critical contacts.

134 d shape and showed a significant increase in beta-strand formation in the final tetramer unit relativ

135 eet is shown to be built up from in-register beta-strands formed by nearly the entire protein sequenc

136 e pair of beta-sheets motif is built up from beta-strands formed by only the last two-third of the pr

137 alpha-Strands and beta-strands formed in the initially unstructured N-term

138 ey Abeta self-recognition sites spanning the beta strands found in cross-beta protofibril structures,

139 tes dissociation of a noncovalently attached beta-strand from a circularly permuted split GFP, allowi

140 ted that detachment of the short, C-terminal beta-strand from the soluble fold exposes key amyloidoge

141 the hypothesis that increasing the number of beta-strands, from two to three, increases the stability

142 al residues of the Abeta subunit, indicating beta strand-g3p interactions.

143 parallel beta-sheets have swapped their last beta-strands giving a novel sheet topology which is an i

144 outer beta-strand H, which hydrogen bonds to beta-strand H' of a neighboring subunit in the tetramer,

145 dening is greatest for residues in the outer beta-strand H, which hydrogen bonds to beta-strand H' of

146 cess, however the analogous approach for the beta-strand has received less attention.

147 er induce or stabilize secondary structures (beta-strands, helices, reverse turns) in short peptide s

148 Using the same 12-aa beta-strand-hinge-alpha-helix domain, superantigens enga

149 nt upstream of the cleavage site as an extra beta-strand in a central beta-sheet.

150 n the DOPC/DOPG membrane, and is primarily a beta-strand in the DOPE membrane.

151 truncated GFP by substituting as a surrogate beta-strand in the groove vacated by the native strand.

152 r of Abeta42 molecules, each containing four beta-strands in a S-shaped amyloid fold, and arranged in

153 into cruciform tetramers consisting of eight beta-strands in a two-layered assembly.

154 primarily found on cadherins and plexins on beta-strands in extracellular cadherin and Ig-like, plex

155 The identification of seven beta-strands in hbeta2m fibrils indicates that approxima

156 that monomeric Abeta proteins form extended beta-strands in reverse micelles, while an analogue with

157 e Sec61/SecY complex to translocate IDDs and beta-strands in the absence of alpha-helical domains.

158 learning approach (boctopus2) for predicting beta-strands in the barrel.

159 tenon' motifs are shown to join neighbouring beta-strands in the C-terminal barrel domain, and mutati

160 psin-like protease conformation in which two beta-strands in the core of the protease domain undergoe

161 inding, is a flexible loop that connects two beta-strands in the cytokine-binding domain (DII) of IL-

162 rn break crucial hydrogen-bonds bridging two beta-strands in the Greek key motifs at the "tyrosine co

163 from the presence of preformed amyloidogenic beta-strands in the native state.

164 bility mapping to identify several potential beta-strands in the Tom40 protein in isolated mitochondr

165 The precise location and length of beta-strands in the two fibril forms also differ.

166 rearrangement compared with the location of beta-strands in their native immunoglobulin folds.

167 ructure becomes more stable as the number of beta-strands increases, via comparisons among peptides d

168 ing alpha-subdomain compaction, facilitating beta-strand intercalation, and optimizing translation ki

169 usly not only the arrangement of the peptide beta-strands into beta-sheets but also the beta-sheet in

170 mbrane, but it is unclear whether it threads beta-strands into the lipid bilayer in a stepwise fashio

171 stinct, second conformation wherein the last beta-strand is retracted to extend the Ser65 loop and sh

172 itution at the middle of the dimer interface beta-strand is sufficient to generate a fully functional

173 with a parallel in-register organization of beta-strands is capable of seeding the conversion of ful

174 observed in a parallel orientation with the beta-strands, is a typical feature of type A CBMs, altho

175 Mutant constructs show that the beta-strand itself is not required for transcriptional a

176 partially unfolded exchanging among multiple beta-strand-like conformations in solution.

177 We discuss the prominent role of beta-strand-like intermediates in flight toward the nati

178 beta-strand LK peptides with a periodicity of 2.0 induce

179 The loop region linking the beta-strands (loop 4) presents residue 24 in a configura

180 uent hairpin fragments and comparable-length beta-strand-loop-beta-strand models, indicate 2-state fo

181 tophan residues that stabilize a distinctive beta-strand:loop:PPII-helix topology.

182 (OM) beta-barrel proteins composed of 12-18 beta-strands mediate cellular entry of small molecules i

183 pon the presence of Hpm1p, a candidate seven-beta-strand methyltransferase.

184 contains the motifs characteristic of seven-beta-strand methyltransferases, a methyl-accepting subst

185 This domain is buried in the 6-beta-stranded MinE "closed" structure, but is liberated

186 otease accessibility studies, support the 19 beta-strand model for Tom40 with the C-terminal end of t

187 Theoretical calculations on beta-strand models analogous to 7, 8 and 9 provide furth

188 ments and comparable-length beta-strand-loop-beta-strand models, indicate 2-state folding for all top

189 The helix, turn, and beta-strand motifs of biopolymer folded structures have

190 osed of four structured domains, including a beta-stranded N-terminal domain.

191 2 site 2 TQC motif forms a uniquely extended beta-strand, not observed in other dynein light chain-ta

192 th an N-terminal segment preceding the first beta-strand occluding the lumen of the barrel.

193 ntermolecular beta sheet with the N-terminal beta strands of arrestin.

194 ntified were located at loops connecting the beta strands of MOG.

195 r PapC, and a loop between the 12th and 13th beta strands of the TD (beta12-13 loop) was found to fac

196 A chimaera S-peptide composed of the 10th beta-strand of GFP (s10) and a kinase substrate peptide

197 l, placed at the N-terminal end of the first beta-strand of Het-s fibrils, is significantly reduced i

198 and sfCherry11 are derived from the eleventh beta-strand of super-folder GFP and sfCherry, respective

199 x of the muscle endplate AChR is linked to a beta-strand of the extracellular domain that extends to

200 ions in WDR1 affecting distinct antiparallel beta-strands of Aip1 were identified in all patients.

201 When beta-strands of an amyloid are arranged parallel and in

202 etwork flips nearly 90 degrees , and the two beta-strands of each monomeric unit move apart, to give

203 selective loss of O-Man glycans on specific beta-strands of EC domains, suggesting that each isoenzy

204 de scan revealed that TamA and BamA bind the beta-strands of FimD, and do so selectively.

205 One alpha-helix and three central beta-strands of PASGtYybT are noticeably shorter than th

206 r structure but intercalates between the two beta-strands of the amyloid fibril and binds to hydropho

207 eta-barrel of BamA to induce movement of the beta-strands of the barrel and promote insertion of the

208 the concave surface of the VLR formed by the beta-strands of the leucine-rich repeat modules.

209 highly conserved sites localized to specific beta-strands of their extracellular cdh (EC) domains.

210 nd F' in the tetramer, while the B, C, and E beta-strands of this sheet remain stable.

211 oop and to plasticity in accommodating extra beta-strands of variable length.

212 ns reveal that interactions between shearing beta-strands on the threaded and knotting loops provide

213 r interactions with MinD, giving rise to a 4-beta-stranded "open" structure through an unknown mechan

214 h at the C terminus, whereas the presence of beta-strands or only a short alpha-helical stretch leads

215 Ig-like fold encompassing seven antiparallel beta-strands organized in two beta-sheets, packed into a

216 atic interactions across non-hydrogen-bonded beta-strands outside the iLBPs, arguing for the generali

217 provide a flat geometry to seed the ordered beta-strand packing of the fibrils.

218 ed upon association with IMPs; resulting IMP-beta-strand peptide complexes resisted aggregation when

219 2) oligomers and fibrils suggest that folded beta-strand peptide conformations form early in the cour

220 beta-strand peptides enabled clear visualization of flex

221 beta-strand peptides self-assemble in solution as filame

222 We designed beta-strand peptides that stabilize integral membrane pr

223 rmation, in which the substrate binds atop a beta-strand platform in the 130's region.

224 hanges to Val(8) on the exterior side of the beta-strand, possibly through contacts to Lys(18) Thus G

225 AP1, revealed an extension of the N-terminal beta-strand previously shown to cross between protomers

226 demonstrate that two valine (V) residues and beta-strand propensity in QVKEVTQ are structurally impor

227 between the Met-129 and Val129 proteins, but beta-strand propensity was similar.

228 the presence in their structures of a seven-beta-strand protein fold.

229 hydroxamate uptake component A (FhuA), a 22-beta-stranded protein containing an N-terminal 160-resid

230 dified conformational ensemble typified by a beta-strand rearrangement.

231 egatively charged and is occupied by a short beta-strand, referred to as the intrinsic ligand, explai

232 escent protein (GFP), i.e., split GFP with a beta-strand removed, that were found to behave different

233 edicted to extend perpendicularly across the beta-strands, requiring them to bend to match the concav

234 e propose that Pro substitution of interface beta-strand residues is a viable strategy for generating

235 interactions by substituting dimer interface beta-strand residues with proline (Pro) results in fully

236 rvation of a continuous 20-residue elongated beta-strand (residues 39-58), the latter being a salient

237 ha-helices enwrapping a pair of antiparallel beta-strands (ribbon).

238 O binds to TRiC directly, mainly through its beta-strand rich, DNA-binding domain (AML-(1-175)), with

239 binding to TRiC mapped predominantly to the beta-strand rich, DNA-binding domain of Stat3.

240 X-ray scattering (SAXS) data show that this beta-strand-rich conformation converts the PE membrane t

241 es demonstrate that alpha-synuclein can form beta-strand-rich oligomers that are neurotoxic, and rece

242 tor, NDUFAF5, belongs to the family of seven-beta-strand S-adenosylmethionine-dependent methyltransfe

243 esidues in the helices and on the surface of beta-strands S3, S9, and S10.

244 pic labels at I32, M35, G37, and V40 exhibit beta-strand secondary chemical shifts in 2-dimensional (

245 hemical shifts for EmrE were consistent with beta-strand secondary structure for the loop connecting

246 s of labeled residues that are indicative of beta-strand secondary structure.

247 omains, which are each assembled from paired beta strands secured by disulfide bonds and grasp two si

248 pts a beta-helical architecture, in which 18 beta-strand segments are arranged in six consecutive win

249 h of BacA filaments, and the distribution of beta-strand segments identified by solid-state NMR, we p

250 drophobic residues located in the identified beta-strand segments suggest that bactofilin folding and

251 repeat unit comprising at least two extended beta-strands, separated by a turn stabilized by a Asp(25

252 ucture prediction programs predicted a short beta-strand separating two acidic domains.

253 d short amyloid-like aggregation-prone cross-beta-strand sequences within the putative PFMG1 pseudo-E

254 tations in the moving beta5 and neighbouring beta-strands shift the Ub/Ub-CR equilibrium.

255 d beta-barrel consisting of six antiparallel beta-strands similar to what was observed in the hepatit

256 ture continuous wave (CW) experiments of the beta-strand site showed two distinct components that wer

257 topology formed by 2 sheets of antiparallel beta strands stabilized by the hallmark disulfide bond b

258 ystine knot structure, with two antiparallel beta-strands stabilized by three disulfide bridges.

259 mog1p"-fold consisting of seven antiparallel beta strands stacked between alpha helices.

260 llel heterodimeric coiled-coil motif for the beta-strand stalk in this antibody.

261 rm a very unusual architecture composed of a beta strand "stalk" that supports a structurally diverse

262 3 (CDR3H) that folds into a solvent-exposed beta-strand "stalk" fused to a disulfide crosslinked "kn

263 By modifying the beta-strand "stalk" of BLV1H12 with sequences derived fr

264 ed hairpin feature is its anti-parallel, two beta-strand stem, which we show by mutagenesis to be cri

265 ton are mediated by a drastic alpha-helix-to-beta-strand structural transition.

266 ttern of high and low SASA consistent with a beta strand structure.

267 ly random coil in the nanosphere-gel adopt a beta-strand structure and are less mobile with HAP bindi

268 domains display a similar three antiparallel beta-strand structure and interact with the same Cx43CT(

269 ETTA and MD simulations resulted in a unique beta-strand structure distinct from the conventional amy

270 Solid-state NMR demonstrated that beta-strand structure of the cross-linking domains domin

271 the formation of aggregation-prone extended beta-strand structure within rPFMG1.

272 ely folded proteins with an all antiparallel beta-stranded structure.

273 copper-catalyzed oxidation promotes extended beta-strand structures that lack a cooperative fold.

274 tend to distances commensurate with extended beta-strand structures within the earliest stages of agg

275 yl group of the terminal adenosine towards a beta-strand, such that an aminoacylated tRNA at this pos

276 he isolated TrkAIg2 domain crystallizes as a beta-strand-swapped dimer in the absence of NGF, occludi

277 The N-terminal portions of HAP form a beta-strand that inserts between two IL-17A monomers whi

278 The Ana2 peptides form beta-strands that extend a central composite LC8 beta-sa

279 result in the ordering of two anti-parallel beta-strands that protrude from each monomer and allowed

280 the core of Tau fibrils assembles from short beta-strands, the properties of the much longer unstruct

281 wo peptides is the type of beta-hairpins and beta-strands they populate.

282 Each subunit contributes three beta-strands to adjacent subunits to form a core seven-s

283 r internal linear motifs of proteins bind as beta-strands to form an extended antiparallel beta-sheet

284 ion into amyloid fibrils, they also use such beta-strands to stabilize the disrupted catalytic site r

285 ithin the N-terminal domain, which undergoes beta-strand-to-alpha-helix and alpha-helix-to-beta-stran

286 structural features that included an unusual beta-strand topology, a number of extended loops and a p

287 eta-strand-to-alpha-helix and alpha-helix-to-beta-strand transitions during catalysis, interacts with

288 nes, a time-dependent increase in aggregated beta-strand-type structure in CAPs with relatively high

289 a-helical domains have to precede the IDD or beta-strands, whereas in mammalian cells, C-terminally l

290 N-terminal F(1-94) domain with four-parallel beta-strands, which are intermittently surrounded by fou

291 cated RRM2 fragments with abnormally exposed beta-strands, which can oligomerize into high-order incl

292 point, causing the local formation of short beta-strands, which move the path of the chain by 120 de

293 ve site of the enzyme by forming an extended beta-strand with Glu(40) or Tyr(46) inserted into the S1

294 nterfered with the interaction of a collagen beta-strand with the beta-sheet structure of Fn modules

295 ayers of beta-sheets possessing antiparallel beta-strands with each being anchored by a pair of cyste

296 of strong self-recognition contacts between beta-strands with high hydrophobic content.

297 eta-strands and the other involving GFCC'C'' beta-strands, with the former burying one prominent glyc

298 This destabilizes the beta-strands within the (beta/alpha)8-barrel domain and

299 ate antiparallel intermolecular alignment of beta-strands within the oligomers.

300 The truncated RRM2, as well as two beta-strands within the RRM2, form fibrils in vitro with