ライフサイエンスコーパス: beta1 adrenergic receptor

1 stitution at residue 389 (Arg389Gly), in the beta1 adrenergic receptor.

2 the activation of a Gs-coupled receptor, the beta1-adrenergic receptor.

3 was strongly enhanced only by the activated beta1-adrenergic receptor.

4 nesis in iBAT was eliminated in mice lacking beta1-adrenergic receptors.

5 rease in calcium current was attributable to beta1-adrenergic receptors.

6 the released norepinephrine on myocytes are beta1-adrenergic receptors.

7 prolonged 5 Hz stimulation when paired with beta1-adrenergic receptor activation.

8 Each was genotyped for beta1-adrenergic receptor (ADRB1) Arg389>Gly and G-prote

9 ssociated with changes in gene expression of beta1-adrenergic receptor (ADRB1) or other calcium handl

10 The beta1-adrenergic-receptor (ADRB1) antagonist metoprolol

11 ion protected myocytes from death induced by beta1-adrenergic receptor agonists by preventing cytosol

12 This GIPC effect was specific for the beta1-adrenergic receptor and was dependent on an intact

13 d extend consequences of genetically variant beta1-adrenergic receptors and G-protein receptor kinase

14 er effects for the Arg389Gly polymorphism of beta1-adrenergic receptors and the intron 16 in/del poly

15 hyperpolarization-activated cation channels, beta1-adrenergic receptors, and NMDA receptors.

16 h post-handgrip-exercise ischaemia (PEI) and beta1 -adrenergic receptor (AR) blockade.

17 The human beta1-adrenergic receptor (AR) and hamster beta2-AR tran

18 a reciprocal down-regulation occurs between beta1-adrenergic receptors (ARs) and the cardioprotectiv

19 ably transfected with alpha1A-, alpha2A-, or beta1-adrenergic receptors (ARs) in an inducible express

20 orepinephrine acting through alpha1beta- and beta1-adrenergic receptors (ARs).

21 ter kidney cells stably expressing the human beta1-adrenergic receptor (beta 1AR) to agonist over a 2

22 the second extracellular loop of the cardiac beta1-adrenergic receptor (beta1-AR) are thought to cont

23 n 324 in helix 6 of the wild-type (WT) human beta1-adrenergic receptor (beta1-AR) generated mutant re

24 The beta1-adrenergic receptor (beta1-AR) is a target for tre

25 The beta1-adrenergic receptor (beta1-AR) mediates several fu

26 s study, we evaluated the impact of 2 common beta1-adrenergic receptor (beta1-AR) polymorphisms (G389

27 fect of protein kinase C (PKC) activation on beta1-adrenergic receptor (beta1-AR) regulation of the c

28 cids within amphipathic helix 8 of the human beta1-adrenergic receptor (beta1-AR) were mutagenized to

29 ral G-protein coupled receptors, such as the beta1-adrenergic receptor (beta1-AR), contain polyprolin

30 (AKAP5) in trafficking and signaling of the beta1-adrenergic receptor (beta1-AR).

31 to the exclusion of caveolin-1, caveolin-2, beta1-adrenergic receptors (beta1-AR), beta2-AR, Galpha(

32 The beta1 adrenergic receptor (beta1AR) is recognized as a c

33 ST reduces activation of the MAPK pathway by beta1-adrenergic receptor (beta1AR) agonists.

34 Based on bioinformatic analysis, beta1-adrenergic receptor (beta1AR) and other components

35 y zinterol or isoproterenol plus a selective beta1-adrenergic receptor (beta1AR) antagonist CGP 20712

36 Antibodies to the beta1-adrenergic receptor (beta1AR) are detected in a su

37 hingosine-1-phosphate receptor 1 (S1PR1) and beta1-adrenergic receptor (beta1AR) are G-protein-couple

38 The beta1-adrenergic receptor (beta1AR) is a G protein-coupl

39 The beta1-adrenergic receptor (beta1AR) is a key cell surfac

40 The beta1-adrenergic receptor (beta1AR) is known to be local

41 n kinase C (PKC) regulates the expression of beta1-adrenergic receptor (beta1AR) mRNA in rat C6 gliom

42 G protein-coupled receptors such as the beta1-adrenergic receptor (beta1AR) must be trafficked t

43 A tenet of beta1-adrenergic receptor (beta1AR) signaling is that st

44 beta1-Adrenergic receptor (beta1AR) stimulation confers

45 cal fragment screening of a thermostabilized beta1-adrenergic receptor (beta1AR) using surface plasmo

46 has decreased function, and a variant of the beta1-adrenergic receptor (beta1Arg389) has increased fu

47 Here, we hypothesized that activation of beta1-adrenergic receptors (beta1ARs) localized to ghrel

48 beta1-adrenergic receptors (beta1ARs) mediate catecholam

49 yl terminus as bait, we identified the novel beta1-adrenergic receptor-binding partner GIPC in a yeas

50 In contrast, during beta1 -adrenergic receptor blockade, LV apical rotation,

51 gth during post-exercise ischaemia (PEI) and beta1 -adrenergic receptor blockade.

52 Adrenergic influences were reduced by the beta1-adrenergic receptor blocking agent metoprolol (1.5

53 PIST controls trafficking of the interacting beta1-adrenergic receptor both in the anterograde, biosy

54 Using the beta1-adrenergic receptor carboxyl terminus as bait, we

55 r this interaction is the Ser residue of the beta1-adrenergic receptor carboxyl-terminal ESKV motif.

56 the application of MembStruk and HierDock to beta1-adrenergic receptor, endothelial differential gene

57 Beta1-adrenergic receptors, expressed at high levels in

58 A (PKA), and this is pivotal to activate the beta1-adrenergic receptor gene (Adrb1) and downstream ta

59 reversal of gene expression controlled by a beta1-adrenergic receptor gene network.

60 rotein, GIPC, co-immunoprecipitates with the beta1-adrenergic receptor in COS-7 cells.

61 ailing hearts, because of desensitization of beta1-adrenergic receptor in heart failure.

62 involvement of the TGN in down-modulation of beta1-adrenergic receptor in response to persistent isop

63 n the basal forebrain as well as alpha2- and beta1-adrenergic receptor in the anterior cingulate cort

64 lated because of, for example, activation of beta1-adrenergic receptors in myocardium.

65 Because signaling through the beta1 adrenergic receptor is a key determinant of cardia

66 We find that the predicted structure of beta1-adrenergic receptor leads to a binding site for ep

67 beta1-adrenergic receptor-mediated ERK1/2 activation was

68 nd, the frontal cortex alpha1-, alpha2-, and beta1-adrenergic receptor mRNA levels were reduced throu

69 Neither the Arg389Gly polymorphism in the beta1 adrenergic receptor nor polymorphisms in the beta2

70 of autoimmune antibodies against the cardiac beta1-adrenergic receptor related to dilated cardiomyopa

71 pression of GIPC had no observable effect on beta1-adrenergic receptor sequestration or receptor-medi

72 the t-tubular region and is responsible for beta1-adrenergic receptor signaling-mediated enhancement

73 oid hormone-responsive, and are regulated by beta1-adrenergic receptor signaling.

74 ndrial function and is mediated, in part, by beta1-adrenergic receptor signaling.

75 These data suggest that GIPC can regulate beta1-adrenergic receptor-stimulated, Gi-mediated, ERK a

76 Our data also demonstrate that beta1-adrenergic receptor stimulation activates the mito

77 FLJ00018 is phosphorylated and activated by beta1-adrenergic receptor stimulation-induced EGF recept

78 ave demonstrated that signaling via specific beta1-adrenergic receptor subtypes (beta1ARs) promotes b

79 When applied to the beta1-adrenergic receptor, the method generated 13 novel

80 NE promotes retrieval via the stimulation of beta1-adrenergic receptors, the production of cAMP, and

81 pinephrine (10 micromol/L), mediated through beta1-adrenergic receptors, tissues were freeze clamped.

82 Using (13)C methyl methionine NMR for the beta1-adrenergic receptor, we identify ligand efficacy-d

83 tified squamous cells, but M1-muscarinic and beta1-adrenergic receptors were not detected.

84 carboxyl-terminal cytoplasmic domain of the beta1-adrenergic receptor, which does not bind either to

85 These cells also express the beta1-adrenergic receptor with no beta2-adrenergic recep

86 Stimulation of the beta1-adrenergic receptor with xamoterol, a specific par