ライフサイエンスコーパス: beta5 integrin

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1 sm for regulation of beta1, but not beta3 or beta5 integrins.

2 eated VSMCs, a process mediated, in part, by beta5 integrins.

3 cubation of Ad particles with soluble alphav beta5 integrin also inhibited subsequent Ad internalizat

4 ic vasculature such as alpha(v)beta3/alpha(v)beta5 integrins, aminopeptidase N, and aminopeptidase A.

5 alance between the interactions of annexin V/beta5 integrin and annexin V/active PKCalpha play a role

6 V, which binds to the cytoplasmic domain of beta5 integrin and protein kinase C alpha (PKCalpha), st

7 epletion of SNX17 led to a loss of beta1 and beta5 integrins and associated a subunits from HeLa cell

8 s in vitro via interactions with alphavbeta3/beta5 integrins and neuropilin-1 (NRP-1).

9 In contrast, neither beta3 nor beta5 integrins are alpha2-6 sialylated, regardless of t

10 , strongly suggesting that neither beta3 nor beta5 integrins are essential for neovascularization.

11 V (Penetratin (Pen)-VVISYSMPD) that binds to beta5 integrin but not to PKCalpha was used.

12 inds avidly to the alpha(v)beta3 and alpha(v)beta5 integrins but does not bind to other closely relat

13 nhibited TGF-beta-inducible transcription of beta5 integrin by an interaction with a TGF-beta respons

14 chondrocytes and that binding of annexin Vto beta5 integrin controls these interactions and ultimatel

15 The interaction between TAP20 and beta5 integrin cytoplasmic domain was demonstrated by pr

16 ted RPE phagocytosis and retinal function in beta5 integrin--deficient mice, which specifically lack

17 interaction or global knockout of Angptl4 or beta5 integrin delayed recovery from peak proteinuria in

18 Alpha(v)beta5 integrin does not participate in phagocytosis by o

19 Ralpha ligands on TGF-beta-induced beta3 and beta5 integrin expression and potential interaction betw

20 We herein report cloning of the beta5 integrin gene promoter and identification of a GM-

21 we investigate the involvement of beta3 and beta5 integrins in the development and progression of ma

22 Blocking the Angptl4-beta5 integrin interaction or global knockout of Angptl4

23 Periostin activated alphaV, beta1, beta3 and beta5 integrins located in the cardiomyocyte cell membra

24 Furthermore, they identify the beta5-/- integrin mouse strain as a new animal model of

25 pha ligands also suppressed TGF-beta-induced beta5 integrin mRNA levels.

26 nt was not inhibited by expression of mutant beta5 integrin, nor was alphavbeta5 integrin-mediated en

27 ce lacking beta3 integrins or both beta3 and beta5 integrins not only support tumorigenesis, but have

28 TG2 closely associated with beta1 and beta5 integrins on the surface of drug-resistant MCF-7 (

29 RPE expressed both alpha(v)beta3 and alpha(v)beta5 integrins, only alpha(v)beta3 was expressed at bir

30 ected s.c. into mice lacking beta3- or beta3/beta5-integrins or various selectins show enhanced tumor

31 integrin but not neutralizing antibodies to beta5 integrin prevented the hypoxia-induced increase in

32 A, 50 micromol/L) inhibited TGF-beta-induced beta5 integrin protein expression by 72+/-6.8% and 73+/-

33 monstrate that this process requires alpha(v)beta5 integrin, rather than alpha(v)beta3 integrin utili

34 EBV infection increases alpha(v), beta3 and beta5 integrin subunit mRNAs as well as upregulates the

35 The individual alphav and beta5 integrin subunits are also reduced but only partia

36 a peptide containing a alpha(v)beta3/alpha(v)beta5-integrin targeting domain fused to a proapoptotic

37 PARalpha activators inhibit TGF-beta-induced beta5 integrin transcription in VSMCs through a novel in

38 ments demonstrated codistribution of alpha(v)beta5 integrin with internalized ROS.

39 s the Ad coreceptor alpha(v)beta3 or alpha(v)beta5 integrins, yet these cells are efficiently infecte

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