ライフサイエンスコーパス: betacellulin

1 or family members, epigen, amphiregulin, and betacellulin.

2 gulin were less than those induced by EGF or betacellulin.

3 de, hepatocyte growth factor/scatter factor, betacellulin, activin A, or exendin-4 failed to induce p

4 enin3, the islet-defining factor, along with betacellulin, an islet growth factor.

5 the terminal 48 or 50 amino acids of mature betacellulin and a binding defective form of Pseudomonas

6 results provide evidence that expression of betacellulin and epiregulin in the uterus requires the p

7 e expression of two additions to the family, betacellulin and epiregulin, are exquisitely restricted

8 These data identify a novel receptor for betacellulin and establish that different EGF family lig

9 ave differently from the EGF family hormones betacellulin and neuregulins.

10 ased vascular leakage apparently mediated by betacellulin and signaling via the epidermal growth fact

11 ave stimulated this panel of cell lines with betacellulin and two other EGF family members, EGF itsel

12 AM10 emerged as the main sheddase of EGF and betacellulin, and ADAM17 as the major convertase of epir

13 Betacellulin belongs to the family of epidermal growth f

14 EGF, TGFalpha, and betacellulin (BTC) appear to mainly stimulate receptor a

15 binding epidermal growth factor (HB-EGF) and betacellulin (BTC) are activating ligands for EGF recept

16 E2/E3 cells were displaced by HRG and betacellulin (BTC) but not by other EGF-like ligands tha

17 Betacellulin (BTC) is a member of the EGF ligand family

18 (TGF)-alpha, but not with amphiregulin (AR), betacellulin (BTC) or epiregulin (EPR), increased fetal

19 shedding of epiregulin and had no effect on betacellulin (BTC) processing.

20 en endothelial cells and NSCs, and show that betacellulin (BTC), a member of the EGF family and one o

21 ases that is activated by neuregulins (NRG), betacellulin (BTC), and heparin-binding EGF-like growth

22 -200 targets, including amphiregulin (AREG), betacellulin (BTC), and the transcription factor GATA6,

23 ascular endothelial growth factor C (VEGFC), betacellulin (BTC), EGF, epiregulin (EREG), and other me

24 identified novel modulators of IFN response-betacellulin (BTC), interleukin 11 (IL-11), and IL-17F-t

25 factor (EGF), neuregulin 1-beta (NRG1-beta), betacellulin (BTC), transforming growth factor-alpha (TG

26 tely reversed by a combination of Neurod and betacellulin (Btc), without producing hepatitis.

27 ively similar to another EGF family hormone, betacellulin (BTC).

28 he data herein demonstrate that heregulin or betacellulin, but not EGF, promotes the rapid translocat

29 rin-binding EGF-like growth factor (HB-EGF), betacellulin, epiregulin, and epigen.

30 We also revealed that betacellulin, IL-17, and IL-11 cytokines have the novel

31 While evidence suggests that betacellulin is a ligand for the EGFR, the ability of be

32 Betacellulin is a member of the epidermal growth factor

33 gulin, transforming growth factor-alpha, and betacellulin mRNA as compared with wild type glands.

34 (HB)-EGF and amphiregulin (AR), and reduces betacellulin mRNA levels.

35 phosphorylation, the EGF-like growth factors betacellulin, neuregulin-1beta, neuregulin-2beta, and ne

36 es expressing a single erbB family receptor, betacellulin not only stimulated EGFR tyrosine phosphory

37 ike growth factor, amphiregulin, epiregulin, betacellulin, or heregulin beta1 that bind to either the

38 investigated the ectodomain shedding of the betacellulin precursor (pro-BTC) in conditionally immort

39 s we show that the ADAM10 prodomain inhibits betacellulin shedding, demonstrating that it could be of

40 Moreover, betacellulin stimulated a complex pattern of interleukin

41 in the double recombinant Ba/F3 derivatives, betacellulin stimulated a complex pattern of receptor ph

42 ws: (i) EGF, amphiregulin, and EPR; and (ii) betacellulin, TGFalpha, and epigen.

43 r shedding of membrane proteins such as EGF, betacellulin, the amyloid precursor protein, and CD23 fr

44 -1beta to ErbB4 and ErbB3 and the binding of betacellulin to both ErbB4 and ErbB1 does not decrease a

45 lin is a ligand for the EGFR, the ability of betacellulin to regulate other erbB family receptors has

46 Interestingly, betacellulin transcript levels were inversely regulated

47 stimulated shedding of the ADAM10 substrate betacellulin, whereas the ionomycin-stimulated shedding