ライフサイエンスコーパス: betaine aldehyde

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1 sition state for the oxidation of choline to betaine aldehyde.

2 the aldehyde metabolites of polyamines, and betaine aldehyde.

3 red values were 133 s(-1) and 135 s(-1) with betaine aldehyde and 60 s(-1) and 93 s(-1) with choline.

4 sing spectroscopic and kinetic analyses with betaine aldehyde and its isosteric analogue 3,3-dimethyl

5 ation of choline to glycine betaine, forming betaine aldehyde as an enzyme-bound intermediate.

6 xidation of choline to glycine betaine, with betaine aldehyde as an intermediate.

7 oxidation of choline to glycine betaine with betaine aldehyde as enzyme-associated intermediate and m

8 xidation of choline to glycine betaine, with betaine aldehyde as intermediate and oxygen as electron

9 dehydrogenase (SoBADH), efficiently oxidize betaine aldehyde (BAL) forming the osmoprotectant glycin

10 cal steps of flavin reduction by choline and betaine aldehyde being rate limiting for the overall tur

11 ep oxidation of choline via the intermediate betaine aldehyde, catalyzed by choline monooxygenase and

12 ability modulates whether the reduced enzyme-betaine aldehyde complex partitions forward to catalysis

13 We report here high-level expression of betaine aldehyde dehydrogenase (BADH) in cultured cells,

14 hyde, catalyzed by choline monooxygenase and betaine aldehyde dehydrogenase (BADH).

15 hem, such as the spinach (Spinacia oleracea) betaine aldehyde dehydrogenase (SoBADH), efficiently oxi

16 th the betB gene product of E. coli that has betaine aldehyde dehydrogenase activity.

17 n and energy source, and it was deficient in betaine aldehyde dehydrogenase activity.

18 betC genes, encoding choline dehydrogenase, betaine aldehyde dehydrogenase and choline sulfatase, re

19 in rice, yet the origin and evolution of the betaine aldehyde dehydrogenase gene (BADH2) underlying t

20 lones, BADH1 and BADH15, putatively encoding betaine aldehyde dehydrogenase were isolated and charact

21 ce-associated protein/B12D-related protein1, Betaine aldehyde dehydrogenase, and Unknown protein5.

22 heroma by doping the charge labeling reagent betaine aldehyde directly into the DESI solvent spray, l

23 NMR spectroscopic analyses indicated that betaine aldehyde exists predominantly (99%) as a diol fo

24 nt glycine betaine via the route choline --> betaine aldehyde --> glycine betaine.

25 In this study, the oxidation of betaine aldehyde has been investigated by using spectros

26 Betaine aldehyde, incorporated into the spray solvent, r

27 sequential FAD-dependent reactions in which betaine aldehyde is formed as an intermediate.

28 ubstrates, including the osmolyte precursor, betaine aldehyde, lipid peroxidation-derived aldehydes,

29 spectrophotometer upon anaerobic mixing with betaine aldehyde or choline at pH 8, with similar k(red)

30 h a pKa of approximately 6.7 is required for betaine aldehyde oxidation.

31 pendence of the kcat/Km and kcat values with betaine aldehyde showed that a catalytic base with a pKa

32 This enzyme catalyses the conversion of betaine aldehyde to glycine-betaine.

33 dy-state kinetic data with either choline or betaine aldehyde were consistent with the flavin semiqui

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