ライフサイエンスコーパス: biased

1 uting miscarriage to fibroids is potentially biased.

2 al model parameter estimates can be severely biased.

3 directly measured, spatial data products are biased.

4 In such cases, imputation-based methods are biased.

5 ct of plant diversity on productivity may be biased.

6 h H1N1 influenza viruses elicited an Igkappa-biased Ab response directed against the HA globular head

7 Delivering sounds during sleep biased AC activity patterns, and sound-biased AC pattern

8 sleep biased AC activity patterns, and sound-biased AC patterns predicted subsequent hippocampal acti

9 rences in social behaviour may underpin male-biased acquisition of infection and may result in males

10 lly migratory and that migration was not sex-biased across surveyed areas.

11 This SCF variant elicited biased activation of hematopoietic progenitors over mast

12 s are of importance in generating T helper-1 biased adaptive immune responses.

13 ural populations, we find no evidence of sex-biased admixture during the migration that spread farmin

14 us to identify protein substrates that have biased affinities for either oxidation or reduction by P

15 y binds accessible chromatin, its binding is biased against accessible chromatin located at promoter

16 over that northern blotting of small RNAs is biased against short sequences and develop a protocol th

17 pment of CB1 allosteric modulators that show biased agonism and potentially antiobesity behavior via

18 Biased agonism at G protein-coupled receptors constitute

19 ndogenous mGluR1 activator (i.e., endogenous biased agonism at mGluR1) and changes in spinal dynorphi

20 lso suggest parallels between partial and/or biased agonism in RTKs and G-protein-coupled receptors,

21 ively control signaling, a phenomenon termed biased agonism.

22 stin assays, SARs were different, indicating biased agonism.

23 opioid drug (morphine) or a potent G protein-biased agonist (TRV-130).

24 he proinflammatory effects of OT without the biased agonist effects.

25 le compound 81 was identified as a potent Gi biased agonist for KOR with minimal beta-arrestin recrui

26 Here we demonstrate that ML290 is a biased agonist in human cells expressing RXFP1 with long

27 we reveal that TRV120027, a beta-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT

28 xperiments at D2R and consequently represent biased agonists favoring beta-arrestin-2 recruitment ove

29 ypes of KOR antagonists as well as G-protein-biased agonists.

30 as, and in most cases, outperforms existing biased algorithms.

31 our study is best described as egoistically biased altruism, with important implications for our und

32 on or velocity that subsequently resulted in biased amounts of motion-based learning.

33 a protocol enabling quantitative, minimally biased analysis of extracellular RNAs (exRNAs) associate

34 he island reveals that the admixture was sex biased and happened heterogeneously across Madagascar, s

35 usting a minimal peak intensity threshold is biased and inefficient since lipid species and classes v

36 autoantibody levels in IPF patients were HLA biased and inversely correlated with physiological measu

37 ly interpreted as testifying to the power of biased and self-fulfilling processes - is that interpers

38 nslation machinery, known to be highly codon biased and using preferentially fast codons, are highly

39 treatment, gametocyte sex ratio became male-biased and was not significantly different between the D

40 t inflammasome activation and that mimicking biased aPC PAR-1 signaling using parmodulins may be a fe

41 f Si(-O-Si)4-n (-O-Al)n species is spatially biased as opposed to being random.

42 he CARe cohort, downsampled to induce family-biased ascertainment, LT-Fam was correctly calibrated wh

43 The CUME was biased at a potential where the ion would deposit as the

44 ith complex regional pain syndrome only have biased attention for bodily-specific information in the

45 d have multiple underlying causes, including biased attention, impaired decision formation, or a moto

46 wn inflammatory pathway that promotes female-biased autoimmunity.

47 ity was associated with higher anxiety for M-biased averted-gaze fear, while increased left amygdala

48 proxyfan, and iodoproxyfan were all markedly biased away from calcium signaling, and principal compon

49 the estimated effects will be systematically biased away from the null.

50 Female-biased BCL6 targets were enriched for early cGH derepres

51 5-regulated transcriptional repressors: male-biased BCL6, which was repressed, and female-specific CU

52 ems are implicated in diverse domains of sex-biased behavior and pathology, but we lack a basic under

53 hat the epitaxial BaM films with strong self-biased behaviors have good electromagnetic properties in

54 s can modulate threat appraisal and racially biased behaviour in context-dependent ways.

55 sociation-mediated DNA transfer, followed by biased binding into the exonuclease active site.

56 articipants' choices revealed that attention biased both value computation during choice and value up

57 case surveillance, and thus inference may be biased by age-specific variation in measles reporting.

58 that scores inferred from European GWASs are biased by genetic drift in other populations even when c

59 Both hubs were biased by inputs from the insula identified from seed-ba

60 ropose, the one entailing cultural diffusion biased by linguistic differences is the most plausible.

61 el has multiregional applications and is not biased by postdepositional diagenesis, allowing the iden

62 stical patterns of language in acoustics are biased by the arbitrary, language-dependent segmentation

63 c images, not the people, their ratings were biased by the attractiveness of the learned images.

64 The literature is often biased by the heterogeneity of the criteria leading to a

65 Dendritic cell (DC) subsets with biased capacity for CD4(+) and CD8(+) T cell activation

66 In simulations with family-biased case-control ascertainment, LT-Fam was correctly

67 at an outcome-specific conditioned inhibitor biased choice away from actions delivering that outcome

68 a dopaminergic disturbance may underpin drug-biased choice in addiction.

69 frontal gyrus was temporarily disrupted made biased choices more often than a control group.

70 ontal control was temporarily disrupted made biased choices more often than a control group.

71 cruited to prevent heuristics from producing biased choices, the right inferior frontal gyrus, often

72 by miRNA-specific regulation, including sex-biased chromatin accessibility at promoters, rather than

73 omosome through a phenomenon we term trisomy-biased chromosome loss (TCL).

74 so detected quantitative expansion of T cell-biased clones consistent with an adaptive immune respons

75 (1:1) through a computer-generated adaptive biased coin design to either palliative chemoradiotherap

76 stent between different regions and strongly biased compared to the observation-based relationships.

77 We find that betaarrestin-biased compounds, such as fentanyl, are more likely to i

78 loration and without any evidence for payoff-biased copying.

79 of principle that when CRF is in excess, sex-biased CRF1 coupling translates into divergent cell sign

80 n male and female brains, as a result of sex-biased CRF1 signaling.

81 cell and neutrophil infiltration and a Th17-biased cytokine response.

82 trated, acquiring the mechanistic details of biased D2R/G-protein and D2R/beta-arrestin signaling in

83 g" for pathogenicity takes place is based on biased data collected with cells injected i.v., a route

84 on balanced (P50:C50 and P53:C47) or protein-biased diets and induced on carbohydrate-biased diets in

85 ein-biased diets and induced on carbohydrate-biased diets in H. armigera, but was at the highest leve

86 d reduced on either protein- or carbohydrate-biased diets in H. assulta.

87 50 for larvae on optimal versus carbohydrate-biased diets, and significant diet-mediated variation in

88 We report greater sex-biased differential expression in the pituitary as compa

89 Biased differentiation in these progenitors results in a

90 change normal stochastic adatom diffusion to biased diffusion, leading to selective mass transport.

91 ity was associated with higher anxiety for P-biased, direct-gaze fear.

92 ow the pattern of female philopatry and male-biased dispersal.

93 spine calcium dynamics, we propose that this biased distribution in calcium signals is governed by a

94 neity of 5fC and 5caC and reveals the strand-biased distribution of 5fC and 5caC.

95 The constraint factors that regulate the biased distribution of natural form have long since been

96 om the network via the motif's enrichment or biased distribution towards transcription start sites in

97 otetraline unit led to balanced or G protein-biased dopaminergic ligands depending on the stereochemi

98 ans of check-all-that-apply questions may be biased downward.

99 il and blood, the dPCR quantification can be biased due to the presence of inhibitory compounds.

100 or longitudinal random-effects models may be biased due to unmeasured confounding and measurement and

101 movement is suspected to have significantly biased early biomass estimates of highly mobile top pred

102 ite large samples (n > 20 000), and produced biased effect estimates.

103 eptor-transducer interaction, among which no biased efficacy is theoretically possible.

104 using ODN donors produced conversion tracts biased either mostly uni- or bidirectional depending on

105 HT, a dedoped region forms at the negatively biased electrode, increasing the overall resistance of t

106 etwork and by the dynamics of changes in sex-biased epigenetic states.

107 nnaire after the start of exposure creates a biased estimate the total effect of exposure choice on o

108 not identified in these sources results in a biased estimate.

109 mine whether genotyping errors substantially biased estimates of association.

110 cate that loci with missing data can produce biased estimates of key population genetic parameters, a

111 s came from another population, the ABM gave biased estimates of mortality-and often of causal effect

112 s of respiratory symptoms provides the least biased estimates of pneumonia etiology.

113 dling missing data can lead to imprecise and biased estimates.

114 That sex-biased exposure might translate to sex-specific adverse

115 significantly enriched for genes with female-biased expression in developing gonads after the critica

116 We report tissue-specific and sex-biased expression in genes commonly investigated when st

117 rial tissues and the other homoeolog showing biased expression in tip-growth tissues.

118 Sex-biased expression is explained by miRNA-specific regulat

119 at are located on autosomes and exhibit male-biased expression patterns [6].

120 factor VGLL3, which also had a strong female-biased expression.

121 d secreted through the kidneys, exhibit male-biased expression.

122 arise complex feature descriptions in a less biased fashion than user defined plain texts and numeric

123 xtraction, which may result in incomplete or biased features.

124 This may result in inadvertently biased filtering of periodontal reviews and subsequently

125 erleaved with two bilateral regions that are biased for auditory attention, transverse gyrus intersec

126 However, MeDIP-Seq is biased for CpG enriched regions and thus its results nee

127 They are biased for shallow, lowest common denominator informatio

128 015) reported two bilateral regions that are biased for visual attention, superior precentral sulcus

129 of intrinsic disorder, are essential for the biased formation.

130 rization, IF transport becomes directionally biased from the cell center toward the cell front.

131 X chromosome has acquired a paradoxical sex-biased function by redistributing gene contents [5, 6] a

132 nipulation disproportionately influences sex-biased gene expression but show that the direction of ch

133 ifications accompanied these cGH-induced sex-biased gene expression changes.

134 trogen signaling is a major driver of female-biased gene expression in the post-temperature sensitive

135 We find that tissue-specific strain-biased gene expression may be regulated by tissue-specif

136 tic backgrounds showed a striking pattern of biased gene expression on chromosomes 6A and 6D, indicat

137 Sexual dimorphism depends on sex-biased gene expression, but the contributions of microRN

138 be classified into duplications with higher, biased gene loss and bias in gene expression between sub

139 Thus, the temporal, sex-biased gene responses to persistent GH stimulation are d

140 Male-biased genes activated by STAT5 and/or repressed by CUX2

141 Female-biased genes already in an active chromatin state in mal

142 s been found in many other organisms, female-biased genes are more rapidly evolving in sequence, expr

143 ly, our data reveal that the deficit of male-biased genes on the X Chromosomes in Anopheles is a cons

144 ce, expression, and genic turnover than male-biased genes.

145 gnatures of positive selection on young male-biased genes.

146 e genomic and evolutionary properties of sex-biased genes.

147 ough cell contacts and creates directionally biased geometry.

148 during viral infection and that this led to biased helper CD4 T cell differentiation as well as impa

149 Myeloid-biased hematopoietic stem cells (MB-HSCs) play critical

150 ritability estimates to avoid the problem of biased heritability estimation, enabling correct calibra

151 e marrow cells restore quiescence of myeloid-biased HSCs, with implications for blood disorders, agin

152 te constants in biofilm can be significantly biased if the boundary layer thickness is not accurately

153 ate that previous empirical studies could be biased in assessing climate change impacts by ignoring t

154 In fact, substitution rates are biased in favor of dominant sex determining chromosomes,

155 blood-brain barrier in a discriminating way biased in favor of non-pathogenic CD8(+) T cells relativ

156 Strikingly, the gene conversion events were biased in favour of long-tract gene conversions in FANCJ

157 st experiences, and that this process can be biased in favour of past choices using incidental remind

158 fespan, which has become increasingly female-biased in recent centuries.

159 reproduction and territories, which is male-biased in the weasels.

160 otent allergen of S aureus and induces a TH2-biased inflammatory response in the airways in an IL-33-

161 cial anxiety disorder (SAD) is maintained by biased information-processing vis-a-vis threat of social

162 , disperse further, suggesting a sociability-biased invasion front.

163 ic interpretations by applying the pertinent biased kinetic models of the charge/spin exchange rates

164 d that nalfurafine, a clinically available G-biased KOR agonist, could also produce DRL disruptions.

165 Here, the sensory-biased LFC results are reproduced using a new task, and

166 n and MD functionality, especially in visual-biased LFC structures.SIGNIFICANCE STATEMENT Lateral fro

167 e show that endomorphin-2 (EM2), an arrestin-biased ligand for microR, lengthens surface lifetimes of

168 In this study we identified two novel biased ligands for the chemokine receptors CCR2 and CCR5

169 tubulin complex proteins (GCPs) that exhibit biased localization toward MT minus ends.

170 a transcription factor expressed by myeloid-biased long term-hematopoietic stem cells, guides the li

171 verage GOM measurements were estimated to be biased low by more than a factor of 2 at six sites, betw

172 the present study, by expressing an arrestin-biased M3 muscarinic receptor-based DREADD (M3D-arr) in

173 and technically important materials for self-biased magnetic microwave devices.

174 es in single-cell RNA-seq data sets in a non-biased manner.

175 We identify the most accurate and least biased method.

176 at chemotactic bacteria exhibited a distinct biased migration toward contaminant sources that resulte

177 Another Z-linked miRNA, the male-biased miR-2954-3p, shows conserved preference for dosag

178 yses uncovered numerous cases of somatic sex-biased miRNA expression, with the largest proportion fou

179 tically male-biased, whereas autosomal ovary-biased miRNAs are female-biased, possibly due to broad h

180 ed across tissues such that autosomal testis-biased miRNAs tend to be somatically male-biased, wherea

181 at the two modified estimators are much less biased, more precise and more accurate than the original

182 Male-biased mutations in genes that escape X-inactivation wer

183 spatial and temporal information to regulate biased Myosin activity.

184 These results highlight the biased nature of the J113863 and UCB35625 that act eithe

185 st pronounced in binocular and ipsilaterally biased neurons, which are the populations that have unde

186 and that Th1 immunity can be imparted to Th2-biased offspring; in some instances, it can be greater t

187 correspond to uniform pixel filling, whereas biased ones exhibit pixel locking, in which the estimate

188 e receptor bound to a classical or G protein-biased opioid agonist, c) Identification of kinetically

189 G causality estimates can be either severely biased or of high variance, both leading to spurious res

190 nalysis, they often produce results that are biased or require excessive computational requirements.

191 Biased, or non-Mendelian, segregation is frequently obse

192 on, whereas laminar restriction results from biased outgrowth toward the outermost IPL.

193 he periodic spatial distribution of reversed biased p-i-n junctions.

194 A simple model for biased partitioning predicts a population structure of l

195 At the species level, biased patterns of synonymous substitutions underpin inc

196 ral excitability instead reflects a state of biased perception, during which a person is more likely

197 an invasion front made of individuals with a biased phenotype.

198 aried in density, genetic diversity, and sex-biased philopatry.

199 s observed when the bottom gold electrode is biased positively.

200 eas autosomal ovary-biased miRNAs are female-biased, possibly due to broad hormonal control.

201 optimization of fragment hit 5b to 13-d as a biased, potent inhibitor of the BRD of the BRPFs with ex

202 lts reveal a neural basis for state-specific biased processing of motivationally relevant cues.

203 ivity with the vmPFC in OCD, consistent with biased processing of the CS+.

204 rrow, where it stimulates a distinct myeloid-biased progenitor subset.

205 s indicates that non-classical monocytes are biased progenitors of alternatively activated macrophage

206 of all lineages through expansion of lineage-biased progenitors.

207 ion into multipotent and downstream lymphoid-biased progenitors.

208 than piggybacking of intronic miRNAs on sex-biased protein-coding genes.

209 contact with the basement membrane, exhibit biased protrusive activity and directed movement along t

210 gressive transposon-like silencing of canola-biased PUFA synthase transgenes.

211 this, most Bt bioassays employ carbohydrate-biased rearing diets.

212 he thrombin-cleavage site and thus initiates biased receptor signaling, triggering only some of the s

213 The two visual-biased regions exhibit MD behavior, whereas the auditory

214 ns exhibit MD behavior, whereas the auditory-biased regions have no more than weak MD responses.

215 and performs best on diets that are protein-biased relative to carbohydrates.

216 l activity) contributes to a T helper type 2 biased response and predisposes to features of AD in mic

217 the HA stem region, also elicited an Igkappa-biased response.

218 the role of recombinant SplD in driving TH2-biased responses and IgE formation in a murine model of

219 ransgenic (tg) C57BL/6 mice, which have Th17-biased responses due to RORgammat overexpression in T ce

220 ces have accrued in a haphazard manner, with biased sampling of natural variation that is driven larg

221 erage was based on outdated, incomplete, and biased science and did not reflect current evidence or s

222 Two recent studies on a specific type of biased segregation in mammalian meiosis suggest that it

223 -counting, reduced the effect of potentially biased self-reports, and produced credible data from ano

224 indered by high quantitative variability and biased sequence counts.

225 ing early on, leading to an increased female-biased sex ratio for the whole brood.

226 We now show a similar but male-biased shrinking (16%) and regrowth (8%) in the standard

227 pathways is termed functional selectivity or biased signaling and is a promising therapeutic strategy

228 sting was the identification of differential biased signaling between the two isoforms.

229 avage/activation of PAR2, possibly through a biased signaling function.

230 Though biased signaling through D2Rs has been demonstrated, acq

231 Both isoforms engender biased signaling, notably for 4-[3-(benzyloxy)propyl]-1H

232 ding, activation, allosteric modulation, and biased signaling.

233 s on the Z Chromosome is expected to be male-biased, since there is no global dosage compensation mec

234 s and persistent in females-regulate the sex-biased, STAT5-dependent expression of hundreds of genes

235 e value must be encoded to establish a value-biased state of preparation for an impending sensorimoto

236 es also had higher antibody titers and a Th1-biased T cell memory response at 75 days p.i.

237 cell technology, but these animals contain a biased T cell receptor (TCR) repertoire that might affec

238 igen-specific gamma interferon-dominated Th1-biased T cell response.

239 When sex ratios are biased, the more numerous sex faces increased competitio

240 ns to benenodin-1 generate peptides that are biased to a single conformer, showing that the switching

241 predicts that individuals with PTSD will be biased to attend to potential dangers in the environment

242 cies and education, subjects are universally biased to base their judgments on number as opposed to t

243 The bacterial protein is here biased to move relatively freely in the bacterial interi

244 at our automated segmentation method was not biased to prevent detection of putative song periodicity

245 than ipsilateral responses and are strongly biased to the cardinal directions.

246 ies of marketed CNS drugs, which are heavily biased toward "traditional" aminergic targets and common

247 The cultivation of bacteria is highly biased toward a few phylogenetic groups.

248 cells in patients with LRBA deficiency were biased toward a TH1-like cell phenotype, which was parti

249 DOCK8-deficient memory CD4(+) T cells were biased toward a TH2 type, and this was at the expense of

250 orest inventory plot locations are spatially biased toward areas with high probability of ancient hum

251 e action of pilocarpine on endogenous M3R is biased toward beta-arrestin.

252 to aggrecan production, a feature which was biased toward collagen production when cells were cultur

253 ostatin and parvalbumin neurons was strongly biased toward Go trials, VIP neurons were similarly acti

254 differences in their calibration, with some biased toward higher precision and others toward higher

255 t phase sensitivity in early visual areas is biased toward higher SFs.

256 e against the original HA that was no longer biased toward Iglambda and possessed differential specif

257 However, sequencing assays are biased toward mutations with minimal fitness impacts and

258 plasticity in intrinsic MB neurons, which is biased toward naturalistic reward learning.

259 cocrystal structure reveals that binding is biased toward occupation of the adenine subpocket of the

260 mentary can show why prosocial behaviors are biased toward physically attractive individuals, as they

261 With a few exceptions, the estimates are biased toward predicting saturation vapor pressures that

262 moment is not entirely veridical, but rather biased toward recently seen stimuli: a positive serial d

263 pathways by way of amino acid-level dynamics biased toward selecting native-like interactions.

264 the hierarchy of the GRN, rather than being biased toward terminal process or discrete functional bl

265 tabilizes beta1ARs in a conformation that is biased toward the cAMP pathway.

266 first-step decision dynamics were initially biased toward the choice representing the highest sum/me

267 TOP2A CCRs are biased toward the distal regions of gene bodies, and TOP

268 operative and the supramolecular helicity is biased toward the helical preference of the sergeant.

269 he funnel-like binding energy landscape more biased toward the native state.

270 Scene domains were biased toward the peripheral visual field.

271 genotypes, despite expression being slightly biased toward the risk allele in heterozygotes.

272 utes in human observers at a given moment is biased toward what was recently seen.

273 , the distribution of memory clones would be biased towards clones activated more recently, or respon

274 iations in irradiance for human subjects are biased towards low temporal frequencies and small magnit

275 extent to which T cell receptors (TCRs) are biased towards MHC proteins in particular has been widel

276 by within-population patterns; gene flow was biased towards nearby plants, and significant small-scal

277 n, the current knowledge on AMF diversity is biased towards temperate ecosystems, whereas little is k

278 set of crystal structures using measurements biased towards the active site geometry.

279 n which the particle sub-pixel positions are biased towards the center of the pixel.

280 etermine that the flow of energy is strongly biased towards the excitation of energetic charge carrie

281 d the introgression pattern is significantly biased towards the gene flow from G. hirsutum into G. ba

282 UL40 (VMAPRTLIL), which is characterized by biased TRBV14 gene usage.

283 ured after the start of exposure can lead to biased treatment effect estimates.

284 To completely understand biased treatment, we must also incorporate these other f

285 ell renal cell carcinoma (ccRCC) is a gender-biased tumor.

286 arge from this residue produced a signalling-biased variant of Free Fatty Acid Receptor 2 in which Gi

287 Selective and biased VH:VL pairing was particularly evident among expa

288 eased cell motility inside the aggregates, a biased walk toward aggregate centroids, and alignment am

289 dress the question of why Tau is GDP-tubulin-biased, we tested whether Tau might affect MT binding of

290 ence in gene loss rates between unbiased and biased WGDs, and how plant genomes have avoided being ov

291 g the traditional product term approach were biased when confounders had sex-dependent associations w

292 mplication is that zygotic sex-ratios become biased when haploid selected loci become linked to the s

293 stment for the prior value can also be badly biased when measured long before exposure initiation.

294 causal effect estimated using an ABM may be biased when parameterized from at least 1 source externa

295 is-biased miRNAs tend to be somatically male-biased, whereas autosomal ovary-biased miRNAs are female

296 y found that the CRF1 receptor (CRF1) is sex biased whereby coupling to its GTP-binding protein, Gs,

297 Gag293-specific CD4(+) T cells proved highly biased, with a predominant usage of the TCRbeta variable

298 pp65, IE1, IE2, and gB was predominantly Th1 biased, with neither the loss nor the accumulation of th

299 wing whole genome duplication (WGD) is often biased, with one subgenome retaining more ancestral gene

300 Despite causing biased zygotic sex-ratios, we find that a period of sex-