ライフサイエンスコーパス: binaural

1 is pitch mismatch may be related to degraded binaural abilities.

2 -the BIC reflects the difference between the binaural ABR and the sum of the monaural ABRs (i.e., bin

3 ely, and changes its spike rate according to binaural acoustic differences.

4 Binaural acoustic signals in the form of phase-locked ac

5 d multiple units in response to monaural and binaural acoustic stimulation.

6 ithin milliseconds, but the actual extent of binaural adaptation is unknown.

7 of coincidence detection affect monaural and binaural AM coding.

8 for LSO neurons to encode both monaural and binaural AM sounds.

9 nature of overlap between systematic maps of binaural and frequency selectivity leads to representati

10 se sounds affected neither the ratio between binaural and monaural responses nor the interaural time

11 also ask how these different adaptations for binaural and spatial hearing might inform and inspire th

12 tivated cortex resulting from the overlap of binaural and tonotopic maps.

13 er range of strategies for ITD coding in the binaural auditory brainstem.

14 he direction of a sound source, although the binaural auditory cues available in the acoustic sound f

15 sitive channel blockers ('photoswitches') in binaural auditory gerbil neurons to show that hyperpolar

16 Low-order binaural auditory neurons with sharp frequency tuning ac

17 e medial superior olive (MSO) is part of the binaural auditory pathway, receiving excitatory projecti

18 quired submillisecond temporal precision for binaural auditory processing, reduced myelination might

19 information about sound stimuli, in part for binaural auditory processing.

20 lateral olivocochlear feedback maintains the binaural balance in neural excitability required for acc

21 A binaural beamforming algorithm was also assessed.

22 This stimulus, named amplitude modulated binaural beat, allows for a parametric and isolated chan

23 We obtained responses to binaural beats and dichotic noise bursts to characterize

24 e developed a biophysically-based model of a binaural brainstem nucleus, the medial superior olive (M

25 bility in noise can be improved using a new, binaural broadband hearing instrument system.

26 ison, randomized crossover design study with binaural broadband hearing instruments and advanced digi

27 the QuickSIN and the HINT measures with the binaural broadband hearing instruments, when compared wi

28 d over a wide range of stimulus levels under binaural, but not monaural, conditions.

29 n affected the synaptic organization at this binaural center in the ascending auditory pathway.

30 , calibrated to reproduce known monaural and binaural characteristics of LSO, generate largely simila

31 In terms of binaural characteristics, most (ca. 53%) labeled neurons

32 ch forms a key element of auditory brainstem binaural circuitry, exhibits all of these characteristic

33 A consistent BF and binaural class were usually observed within a patch.

34 representations of sound azimuth within two binaural clusters in the pallid bat A1: the binaural inh

35 erties, but how spatial tuning varies within binaural clusters is unknown.

36 ations are present locally within individual binaural clusters.

37 h and engineering project entitled Advancing Binaural Cochlear Implant Technology-ABCIT-as well as re

38 idelity of NM neurons, which is essential to binaural coincidence detection in nucleus laminaris.

39 ontrol the submillisecond time resolution of binaural coincidence detection, but little is known abou

40 or olive process sound-localization cues via binaural coincidence detection, in which excitatory syna

41 hase-locked signals to nucleus laminaris for binaural coincidence detection.

42 used these responses to construct inputs to binaural coincidence detector neurons in nucleus laminar

43 ion of maximal activation within an array of binaural coincidence-detector neurons that are tuned to

44 ng but not shifting the window for detecting binaural coincidence.

45 f the brain; this information is crucial for binaural comparisons and sound localization.

46 otentials and thus preserves the accuracy of binaural comparisons.

47 wo nuclei are the first significant sites of binaural convergence in the ascending auditory system, a

48 p is unique in that it is the first place of binaural convergence in the brainstem where monaural exc

49 By varying the degree of binaural correlation, we could accurately change the amp

50 te that ICX neurons integrate the results of binaural cross-correlation in different frequency bands.

51 The resulting binaural cross-correlation surface strongly resembles th

52 strate that the cortical representation of a binaural cue to sound source location is profoundly cont

53 The main binaural cue used by many mammals to locate a sound sour

54 for 2 weeks to moderate noise with no stable binaural cue.

55 superior temporal gyrus (pSTG) and modulated binaural-cue response functions differently in the two h

56 Parallel pathways for binaural cues and for different frequency bands converge

57 the degree of matching between the momentary binaural cues and the preferred values of the neuron.

58 ing work focused on the unmasking enabled by binaural cues at the periphery, and little quantitative

59 haracteristic frequency (CF) and the type of binaural cues available.

60 like humans, not all mammals use both of the binaural cues for sound localization.

61 rriving at a listener's ears, distorting the binaural cues for sound localization.

62 The processing of binaural cues for sound location has been studied extens

63 We determined the ability to use binaural cues in 2 New World bats, Phyllostomus hastatus

64 coustic environment, the processing of these binaural cues needs neuronal adaptation.

65 During scanning, the spectral and binaural cues of localized sound were reproduced by a so

66 Macaques were trained to discriminate binaural cues to sound localization, eventually allowing

67 al time difference (ITD), one of two primary binaural cues used to compute the position of a sound so

68 However, neuronal sensitivity to binaural cues was reversibly altered for a few days.

69 f the sound waveforms reaching the two ears (binaural cues) as well as spectrotemporal analysis of th

70 e mutual relationship of sound amplitude and binaural cues, characteristic to reverberant speech.

71 hleovestibular schwannomas (CVSs) that cause binaural deafness in most individuals.

72 discrepancy is that the extended periods of binaural deprivation typically experienced by cochlear i

73 sures of brainstem activity that include the Binaural Difference (BD), a measure of binaural processi

74 Binaural directional hearing emphasizes high frequencies

75 to characterize the nature and magnitude of binaural distortions caused by modern digital behind-the

76 This study assessed the contributions of binaural ENV and TFS cues for understanding speech in mu

77 that vary with separation of sound sources, binaural envelope (ENV) and temporal fine structure (TFS

78 Binaural EPSCs often showed a nonlinearity that strength

79 ummation of the monaural EPSCs predicted the binaural excitatory response but less well than the summ

80 localization by detecting the coincidence of binaural excitatory synaptic inputs distributed along th

81 Early binaural experience can recalibrate central auditory cir

82 ral ITD coding resulting from deprivation of binaural experience contributes to poor ITD discriminati

83 ng from previous deafness and deprivation of binaural experience may play a role in the poor ITD disc

84 erentially impacted by disruptions of normal binaural experience.

85 anesthetized cats that contrast maximally in binaural experience: acutely deafened cats, which had no

86 SRAF had the highest incidence of binaural facilitation for ILD cues corresponding to midl

87 longer-lasting EPSCs compensate to maintain binaural function with raised auditory thresholds after

88 ase membrane conductance during the decay of binaural glutamatergic EPSCs, thus refining coincidence

89 for assessment tools that enable testing of binaural hearing abilities.

90 input by first finding that foundations for binaural hearing are normally established during early s

91 may relate to the aetiology of amblyaudia, a binaural hearing impairment associated with bouts of oti

92 pect of restoring the functional benefits of binaural hearing in bilaterally implanted human subjects

93 implants (CIs) might promote development of binaural hearing required to localize sound sources and

94 nce: acutely deafened cats, which had normal binaural hearing until experimentation, and congenitally

95 When other cues are available (e.g., in binaural hearing), how much the auditory system actually

96 ers the potential to restore the benefits of binaural hearing, including sound source localization an

97 Binaural hearing, which involves the integration and ana

98 poral processing of low-frequency sounds for binaural hearing, which is impaired in FXS.

99 cation of a sound source requires the use of binaural hearing--information about a sound at the two e

100 rm a critical role in sound localization and binaural hearing.

101 this phenomenon has long been of interest to binaural-hearing researchers for uncovering brain mechan

102 Distinct pathways carry monaural and binaural information from the lower auditory brainstem t

103 is demonstrated that the auditory brain uses binaural information in the stimulus fine structure only

104 Binaural information was analyzed in terms of ITDs, ILDs

105 suggests that bilateral HA users' access to binaural information, namely interaural time and level d

106 previously been assessed for its effects on binaural information.

107 binaural clusters in the pallid bat A1: the binaural inhibition (EI) and peaked (P) binaural interac

108 A major inhibitory, binaural input emerges from glycinergic neurons in the i

109 y auditory brainstem structure that receives binaural inputs and is implicated in processing interaur

110 al precision in detecting the coincidence of binaural inputs dictates the resolution of azimuthal sou

111 The major excitatory, binaural inputs to the central nucleus of the inferior c

112 to these neurons' selectivity for coincident binaural inputs.

113 Binaural integration in the central nucleus of inferior

114 However, it is not known how binaural integration matures shortly after hearing onset

115 vely suggest that ILD sensitivity depends on binaural integration of excitation and inhibition within

116 the open ear's representation, and disrupted binaural integration of interaural level differences (IL

117 ssed combinations of spectral, temporal, and binaural integration.

118 y can use both binaural phase-difference and binaural intensity-difference cues to localize sound.

119 nformation mainly about ITDs and the average binaural intensity.

120 urally uncorrelated noise is consistent with binaural interaction based on cross-correlation.

121 the binaural inhibition (EI) and peaked (P) binaural interaction clusters.

122 One commonly proposed measure is the binaural interaction component (BIC), which is obtained

123 Here, we re-examined binaural interaction in low-frequency (less than approxi

124 uning and sensitivity, response latency, and binaural interaction types all showed spatial variations

125 The distributions of binaural interaction types and onset latency were also e

126 Thus, although binaural interactions are established by bilateral CIs i

127 Thus, both monaural and binaural interactions can occur at single inferior colli

128 Spike rate sensitivities to binaural interaural level difference (ILD) and average b

129 inspired by coincidence detection and by the binaural "latency hypothesis." It is known that the two

130 cy discrimination, level discrimination, and binaural lateralization.

131 ABR and the sum of the monaural ABRs (i.e., binaural - (left + right)).

132 n which ILD varies around a constant average binaural level (ABL) to approximate sounds on the horizo

133 nteraural level difference (ILD) and average binaural level cues were probed in A1 and two ventral co

134 or whichever source had the stronger average binaural level.

135 d if there are frequencies having an average binaural-level advantage over a second source.

136 The benefits of the VGHA over natural binaural listening observed in the fixed condition were

137 luence of frequency-specific features of the binaural localization cues experienced by the individual

138 or functions as diverse as Hebbian learning, binaural localization, and visual attention.

139 HAs were placed on a binaural manikin, and stimuli were presented from an arc

140 articipate in the formation of tonotopic and binaural maps in primary auditory cortex.

141 na in rabbit and in human listeners: (a) the binaural masking level difference (BMLD) and (b) differe

142 The binaural masking level difference (BMLD) is a phenomenon

143 Budgerigars show 8 dB of free-field binaural masking release when signal and noise are prese

144 the signal and noise are separated in space (binaural masking release).

145 parate target speech from either monaural or binaural mixtures, as well as microphone-array recording

146 In this article, we propose a binaural model that focuses on grouping, specifically on

147 Much of the previous binaural modeling work focused on the unmasking enabled

148 of coexisting neurological deficits and the binaural nature of auditory inputs.

149 In one binaural neuron with ipsilaterally evoked IPSCs, contral

150 nsists of an array of coincidence detectors--binaural neurones that respond maximally to simultaneous

151 This suggests that binaural neurons are tuned to acoustical features of eco

152 We used in vivo patch-clamp recordings of binaural neurons in the Mongolian gerbil and pharmacolog

153 The binaural neurons of the medial superior olive (MSO) act

154 In the mammalian auditory brainstem, binaural neurons of the medial superior olive (MSO) are

155 We have explored this issue in the binaural neurons of the medial superior olive (MSO), who

156 t ascending auditory pathways, including the binaural neurons of the medial superior olive (MSO).

157 r FMRP in regulating dendritic properties of binaural neurons that are essential for low-frequency so

158 In three binaural neurons, ipsilateral sound evoked a large IPSC

159 ng the azimuth depends on the sensitivity of binaural nuclei in the auditory brainstem to small diffe

160 herited their binaural property from a lower binaural nucleus or the EI property was created in the I

161 Such neurons are indeed found in the binaural pathways and are referred to as "peak-type." Ho

162 The results suggest that different binaural pathways through the low-frequency ICC may be f

163 rpen the encoding of fine structure and feed binaural pathways.

164 Understanding binaural perception requires detailed analyses of the ne

165 addition, LSO neurons are also sensitive to binaural phase differences of low-frequency tones and en

166 on, empirically-observed level-dependence of binaural phase-coding was reproduced in the framework of

167 ure tones, indicating that they can use both binaural phase-difference and binaural intensity-differe

168 Moreover, they were able to use the binaural phase-difference cue up to at least 5.6 kHz, wh

169 etermining the trough positions of simulated binaural phase-response curves.

170 Two binaural phenomena in budgerigars related to the detecti

171 h predictions of cross-correlation models of binaural processing and that the psychophysical detectio

172 s impact on biological processes and suggest binaural processing as a possible contributor to more pr

173 en maintains right cortical dominance during binaural processing but does not fully overcome effects

174 non-musicians, we do not know to what extent binaural processing contributes to this advantage.

175 h ear do not fully overcome deafness-related binaural processing deficits, even after long-term exper

176 aris (NL), the first nucleus responsible for binaural processing in chickens, neuronal excitability i

177 roencephalography demonstrated impairment of binaural processing in children who are deaf despite ear

178 e majority of IC units, bicuculline degrades binaural processing involved in directional coding, ther

179 over a monaural prosthesis by harnessing the binaural processing of the auditory system.

180 h on the similarities and differences in the binaural processing strategies adopted by birds and mamm

181 More recent extensions incorporate binaural processing to account for the summation of loud

182 is (NL) is a brainstem nucleus necessary for binaural processing, analogous in structure and function

183 e the Binaural Difference (BD), a measure of binaural processing, we showed that a period of unilater

184 he grouping or source-separation benefits of binaural processing.

185 d interest in clinical objective measures of binaural processing.

186 rgence for nearly all ascending monaural and binaural projections.

187 locations are computed by integrating neural binaural properties and frequency-dependent pinna filter

188 of the lateral lemniscus that inherit their binaural properties directly from the lateral and medial

189 The present study is the first report on binaural properties of auditory neurons with CIs in unan

190 ation in A1 is a clustered representation of binaural properties, but how spatial tuning varies withi

191 differ in discharge patterns, latencies, and binaural properties.

192 ity of EI cells, either they inherited their binaural property from a lower binaural nucleus or the E

193 ost high-frequency-sensitive LSO neurons are binaural, receiving inputs from both ears.

194 urones in the auditory brainstem to create a binaural representation.

195 The binaural response magnitude, however, was only 64-74% th

196 rse group, even though they exhibit a common binaural response property.

197 However, nearly all possible types of binaural response to sound localization cues were repres

198 egree to which that input contributed to the binaural response.

199 One zone may contain neurons with binaural responses that combine the properties of the in

200 the various projections played in generating binaural responses, we used modeling to compute a predic

201 This projection preserves binaural segregation in that ipsilateral NM projects to

202 The precision of this binaural segregation is evident at the earliest developm

203 hat EphA4 acts as a guidance molecule during binaural segregation.

204 expressed EphA4 during the establishment of binaural segregation.

205 We find that CHL shapes A1 binaural selectivity during two early critical periods.

206 organized with respect to both frequency and binaural selectivity.

207 Recent studies have shown that binaural sensitivity adapts to stimulation history withi

208 ined a similar proportion of variance as the binaural sensitivity for the acoustic temporal fine stru

209 study, we investigated long-term effects on binaural sensitivity using extracellular in vivo recordi

210 nhibition at the IC, we show that an initial binaural signal essentially reconfigures the circuit and

211 ural cues due to the absence of any relevant binaural signal, there is currently no proper explanatio

212 d of inhibition from the DNLL and respond to binaural signals as weakly inhibited or monaural cells.

213 ontext-dependent processing of low-frequency binaural signals in the IC.

214 ereby allows IC cells to respond to trailing binaural signals that were inhibitory when presented alo

215 itudes increased with intensity, even though binaural signals with the same ipsilateral intensities g

216 at property is a change in responsiveness to binaural signals, a change dependent on the reception of

217 The primary cues for binaural sound localization are comprised of interaural

218 We measured the tuning of Ipc units to binaural sound localization cues, including interaural t

219 y nuclei with identified roles in processing binaural sound localization cues, the role of the SPON i

220 rates, and abnormal coding of frequency and binaural sound localization cues.

221 The current dominant model of binaural sound localization proposes that the lateral po

222 made still more demanding by the process of binaural sound localization that utilizes separate compu

223 is an inhibitory hub considered critical for binaural sound localization.

224 ies on the neural processing of monaural and binaural spatial cues that arise from the way sounds int

225 iCIs and approaches for promoting the use of binaural spatial cues.

226 cally to nucleus laminaris (NL), maintaining binaural specificity with projections to either dorsal o

227 the localization cue values and the neurons' binaural spectrotemporal response properties.

228 s the linear transformation from monaural to binaural spike responses.

229 Importantly, binaural spiking response is generated apparently from a

230 the contralateral field, confirming that the binaural SRFs were shaped by contralateral inhibition.

231 e ASSRs were assessed using varying rates of binaural stimulation (auditory click-trains; 10-50 Hz in

232 leus laminaris neurons for both monaural and binaural stimulation increased with sound intensity unti

233 de either by doubling monaural current or by binaural stimulation produced equivalent responses.

234 Relative to binaural stimulation, presentations of the VS stimuli to

235 Using this technique and monaural or binaural stimulation, responses in the IC that reflect i

236 To mimic the arrival of PSCs during binaural stimulation, two stimulus trains were summed at

237 nts and modeling showed that, for simplified binaural stimuli (EPSC pairs in a noisy background), spi

238 ally when using monaural stimuli compared to binaural stimuli.

239 ed the time course and topography of ERPs to binaural syllables or complex tones in dichotic listenin

240 K(v)1 channels are important for preserving binaural synaptic timing.

241 ty to insure their coincident arrival at the binaural targets.

242 The ability to process binaural temporal fine structure (TFS) information was a

243 es are important for speech intelligibility, binaural TFS cues are critical for perceptually segregat

244 l, the results from this study revealed that binaural TFS cues, especially for frequency regions belo

245 the assessment of sensitivity to changes in binaural TFS for older listeners without or with hearing

246 the TFS-AF test yielded a graded measure of binaural TFS sensitivity for all listeners.

247 We now know of 3 bat species that cannot use binaural time cues and 2 that can.

248 this did not support significant effects of binaural timing cues in either auditory cortex.

249 ponses, adult patterns in cortical coding of binaural timing cues were measured.

250 advances, which more consistently represent binaural timing cues.SIGNIFICANCE STATEMENT Multichannel

251 Binaural tonal stimuli induced sustained depolarizations

252 racterized extracellularly with monaural and binaural tone and noise bursts (100- to 250-msec duratio

253 tal conditions: delay conditioning, in which binaural tones preceded air puffs to the right eye by 40

254 /9 carrying an eGFP-reporter gene results in binaural transduction of inner hair cells, spiral gangli

255 This experience-based adjustment of binaural tuning in the AAr helps to maintain mutual regi

256 pendent, because auditory spatial acuity and binaural unmasking (a measure of the spatial contributio

257 tened to voices and nonvocal sounds or heard binaural vocalizations with attention directed toward or

258 ignificant correlation between the degree of binaural weight asymmetry and the best azimuth.

259 s to simultaneous stimulation of both sides (binaural) were compared with responses to monaural stimu

260 The binaural whole-body response direction was compatible wi

261 efore, these neurons would be expected to be binaural with contralateral inhibition.