ライフサイエンスコーパス: binding domain

1 o its coiled-coil 2-leucine zipper ubiquitin binding domain.

2 y binding of ATP/ADP to mtHsp70's nucleotide-binding domain.

3 W7-binding domain of sT, but not the sT-PP2A binding domain.

4 phosphorylates YY1 at serine 365 in the DNA-binding domain.

5 through a small peptide motif within its MT-binding domain.

6 55) also binding the carboxy-terminal ligand binding domain.

7 mains: an R domain, an AAA+ domain and a DNA-binding domain.

8 f Gene 33 is partially dependent on its ErbB-binding domain.

9 of an rcSso7d binding module and a cellulose-binding domain.

10 tein kinase R (PKR) independently of its RNA-binding domain.

11 oxylated Pro-143 within its C-terminal F-box-binding domain.

12 at a highly conserved residue within the DNA binding domain.

13 ique demethylase fold and a canonical folate-binding domain.

14 linker, and the beta-basket of the substrate binding domain.

15 n-binding properties of the Ska1 microtubule binding domain.

16 inds to a site occupied by the gp42 receptor binding domain.

17 binds ATP only in its N-terminal nucleotide-binding domain.

18 lex with Smad3/4 through its N-terminal Smad-binding domain.

19 ediated exclusively by the protein's peptide-binding domain.

20 embrane domain and the C-terminal nucleotide binding domain.

21 ition Motif (RRM) is the most ubiquitous RNA binding domain.

22 is specifically targeted to mRNAs by its RNA binding domain.

23 Raf binding to Rap1 independently of its Ras-binding domain.

24 predicted to affect the highly conserved DNA binding domain.

25 sine (G > A) mutation in the mouse MeCP2 DNA binding domain.

26 in repeats two and three of the microtubule binding domain.

27 ance of parasite PfEMP1 DC8 and group A EPCR-binding domains.

28 ses (NOSs), which contain NADPH/FAD- and FMN-binding domains.

29 ion sequence, one in each of its two AP2 DNA binding domains.

30 ble kinetochore localization and microtubule binding domains.

31 es long, consisting of four eight-nucleotide binding domains.

32 tical proteins with different polysaccharide-binding domains.

33 ners by the combinatorial use of several RNA binding domains.

34 pair factors via their poly ADP-ribose (PAR) binding domains.

35 all loosening effect of the in tandem starch binding domains.

36 domain of RIIbeta is between its second cAMP binding domains.

37 stem was used to express SdrF and its ligand-binding domains.

38 FZD5/FZD8-specific and broadly FZD-reactive binding domains.

39 eoporin Nup2 via its importin alpha- and Ran-binding domains.

40 ATP-binding site 1 formed by the nucleotide-binding domains.

41 Methyl-CpG-binding domain 1 (MBD1) belongs to a family of methyl-Cp

42 ying protein high mobility group nucleosomal binding domain 2 (HMGN2) specifically promotes STAT5 acc

43 The methylcytosine-binding domain 2 (MBD2) protein recruits the nucleosome

44 of Mek null (Smek) interact with methyl-CpG-binding domain 3 (Mbd3) and the complex plays a critical

45 Here, we establish the cholesterol-binding domain 4 of anthrolysin O (ALOD4) as a reversibl

46 We apply this method to study the cAMP binding domain A (CBD-A) of Protein kinase A.

47 ia type 5 (SCA5) L253P mutation in the actin-binding domain (ABD) of beta-III-spectrin causes high-af

48 to-proline substitution (L253P) in the actin-binding domain (ABD) was shown to cause a 1000-fold incr

49 anophilin, specifically its C-terminal actin-binding domain (ABD), is a target of PKA.

50 Talin contains three actin-binding domains (ABDs).

51 hains bound, consistent with the light chain-binding domain acting as a lever arm to amplify nucleoti

52 ains the E2 binding domain but not the Rad50 binding domain acts as a dominant negative inhibitor of

53 2 protein sequence, the DNA and co-repressor binding domains alone are sufficient to avoid Rett syndr

54 conjunction with its N-terminal thioredoxin-binding domain, along with a central regulatory region t

55 Pb10 consists of an alpha-helical capsid-binding domain and an Ig-like domain exposed to the solv

56 ependent effects do not rely on the Chd1 DNA-binding domain and are not due to differences in nucleos

57 933N and N976S located between the glutamate-binding domain and C-terminus.

58 t of M1 mRNA required both an intact NS1 RNA-binding domain and effector domain.

59 Deletion analysis of the sigmaNS RNA binding domain and G3BP1 RNA (RRM) and ribosomal (RGG) b

60 l RNAs: a group II intron, Spinach II, 2-MS2 binding domain and glgC 5 UTR.

61 of the channel; ATP binds at the nucleotide-binding domain and inhibits channel activity.

62 two hexapeptides located in its microtubule-binding domain and is modulated by its projection domain

63 olved at the DANGEROUS MIX2 (DM2) nucleotide-binding domain and leucine-rich repeat (NLR)-encoding lo

64 bacterial products are sensed by nucleotide binding domain and leucine-rich repeat-containing protei

65 s I transactivator (CITA), NLRC5 [nucleotide-binding domain and leucine-rich repeats containing (NLR)

66 the nucleotide-binding domain and substrate-binding domain) in response

67 ce that the HAstV capsid spike is a receptor-binding domain and that the antibody neutralizes HAstV b

68 zation of Gene 33 is regulated by its 14-3-3-binding domain and that the chromatin localization of Ge

69 nt interactions with the double stranded RNA binding domain and the basic region underlie the ability

70 report, we found that the cyclic nucleotide-binding domain and the C terminus of the HCN channel are

71 The N-terminal nucleotide-binding domain and the C-terminal coiled-coil participat

72 terface between its two cytosolic nucleotide binding domains and coupling helices conferred by intrac

73 ved residues of either of the two nucleotide binding domains and determined the effect on BSEP basal

74 vation and quantification of the adsorption, binding domains and dynamics of guest I2 molecules withi

75 ilistic framework that not only exploits DNA-binding domains and specificities, but also integrates o

76 ct arrangement of the kinase and thioredoxin-binding domains and the central regulatory region active

77 h all isoforms sharing the same HDAC and DNA-binding domains and the long isoforms containing a uniqu

78 NLRX1 is unique among the nucleotide-binding-domain and leucine-rich-repeat (NLR) proteins in

79 bunit: the E loop (a loop of the transmitter-binding domain) and a region closer to the amino-terminu

80 gh basal ATPase activity, a unique aggregate binding domain, and almost exclusive expression in stati

81 nit (beta2) of higher fungi lacks a clathrin-binding domain, and experiments showing that AP-2 does n

82 The SFPQ*NONO complex contains an RNA binding domain, and prior work has demonstrated diverse

83 bits the NLS and the neighboring microtubule-binding domain, and RhoA-GTP binding may relieve this in

84 oth its ubiquitin-ligase and C2 phospholipid-binding domains, and involves K48- rather than K63-linke

85 hich contains an additional C-terminal eIF4A-binding domain; and (iii) eIF4G742-1196, which lacks the

86 r topoisomerases, contains a distinctive RNA-binding domain; and deletion of this domain diminishes t

87 omplexa-specific proteins containing AP2 DNA-binding domains (ApiAP2s) was identified in malaria para

88 We demonstrated that, even though their DNA-binding domains are extremely similar, WelLFY and its pa

89 cing conformation whereby the two nucleotide binding domains are misaligned along a two-fold symmetry

90 DNA bricks, which each consist of four short binding domains arranged so that the bricks can interloc

91 ull-length LRH-1, as well as isolated ligand binding domain, bound to PGC1alpha with higher affinity

92 truncated Rint1 protein that retains the E2 binding domain but not the Rad50 binding domain acts as

93 aM) molecules associated with the calmodulin-binding domain (CaM-BD) of these channels.

94 particular, the catalytic domain and the RNA-binding domain can move around a central hinge.

95 n ETS domain, such as ETV6, whose single DNA-binding domain cannot contact both source and destinatio

96 t photoreceptor C-terminal adenosylcobalamin binding domain (CarHC) proteins using genetically encode

97 teract with the regulatory cyclic nucleotide-binding domain (CNB) of the cAMP sensor, EPAC1.

98 In the apo state, the DNA-binding domain contacts the edge of the nucleosome while

99 th the peroxisomal membrane protein acyl-CoA binding domain containing 5 (ACBD5) and that this intera

100 t the Golgi resident protein acyl-coenzyme A binding domain-containing 3 (ACBD3) serves as a target o

101 a gene for a ubiquitously expressed Ets DNA-binding domain-containing transcriptional repressor.

102 the X-ray crystal structure of an EBNA1 DNA-binding domain (DBD) and discovered a novel hexameric ri

103 is protein; a number of mutations in the DNA-binding domain (DBD) are associated with XP disease.

104 RARbeta ligand-binding domain (LBD) and DNA-binding domain (DBD) are physically connected to foster

105 a (RXRalpha), and phosphorylation of the DNA-binding domain (DBD) at Thr-38 in CAR regulates this con

106 les reveal that the direct fusion of the DNA-binding domain (DBD) of Fkh1 to Dbf4 restores the Fkh-de

107 This anchor connects the DNA-binding domain (DBD) with the ligand-binding domain (LBD

108 ability to restore zinc to purified p53 DNA binding domain (DBD), and ability to restore site-specif

109 ich contains a proline-rich region and a DNA binding domain (DBD), is auto-cleaved from the ER membra

110 In our proposed mechanism, DNA-binding-domains (DBD) of R insert in major grooves of O

111 Despite structural similarities in their DNA-binding domains (DBDs), LANA homologs from Kaposi sarcom

112 three variable regions from the E2 receptor-binding domain (Delta123) increases the ability of human

113 The engineered albumin-binding domain-derived affinity protein (ADAPT) is a pro

114 re directed by a contiguous DNA- and histone-binding domain (DHBD) harboring the conserved CENP-C mot

115 intermediate, and mutations in the pTRS1 RNA binding domain did not affect PKR binding or inhibition.

116 at connects two beta-strands in the cytokine-binding domain (DII) of IL-6R.

117 TP and thereby impair ATP-induced nucleotide-binding domain dimerization and ABCB4 function.

118 the AMPAR extracellular domain, with ligand-binding domain dimers losing their local 2-fold rotation

119 Two N-terminal dsRNA Binding Domains (DRBD) are required for activation of PK

120 ow reversible dimerization of the nucleotide binding domains drives opening and closing of the MacB p

121 The effector-binding domain (EBD) of AmpR was purified to homogeneity

122 acquired antibodies against the reticulocyte-binding domains efficaciously blocked reticulocyte bindi

123 ional exchange events observed in the capsid-binding domain enable rearrangements upon binding that c

124 isms that underlie the diversity of this DNA-binding domain exclusively in metazoans are, however, mo

125 Devoid of a DNA-binding domain, FHL2 is a transcriptional cofactor that

126 ical peptide that reconstitutes the collagen-binding domain for integrins GFOGER reverted the assembl

127 rate that affinities of various nucleic acid binding domains for ASO depend on chemical modifications

128 cluding the putative BTE-binding region, and binding domains for eIF4E, eIF4A, and eIF4B; (ii) eIF4G6

129 mor-associated protein, harbors nucleic acid-binding domains for left-handed helix (Z-form) and recep

130 A well-known subset of these proteins with binding domains for the highly diverse sulfated polysacc

131 the pore and contacts the cytoplasmic Ca(2+)-binding domain from a neighbouring subunit.

132 ed fusion protein, which contains the ligand binding domain from a target NHR (human thyroid receptor

133 In this study, we demonstrate that binding domains from autolysins and lysins can be fused

134 orts on the ability of Rap1-heterologous DNA-binding domain fusion proteins to serve as chimeric tran

135 We show how TARPs sculpt the ligand-binding domain gating ring, enhancing kainate potency an

136 WASP homology 1 (WH1) domain and the GTPase binding domain (GBD) of N-WASP and no binding to the ver

137 AXS) experiments using isolated GluA2 ligand-binding domain (GluA2-LBD) are consistent with binding o

138 uorescent probes for PA, by fusing GFP to PA-binding domains, has provided direct evidence for PA dyn

139 sociated protein with four distinct cytokine binding domains, has roles in vasculogenesis, wound heal

140 Several novel PAR-binding domains have been recently identified.

141 s a translocation domain (HN) and a receptor binding domain (HC).

142 ontains four domains (I-IV), and a substrate-binding domain immediately precedes the catalytic domain

143 cture of the functionally essential ICP4 DNA binding domain in complex with a segment from its own pr

144 gnition motif (RRM) is the most abundant RNA-binding domain in eukaryotes, and it plays versatile rol

145 with peptide corresponding to the hemoglobin binding domain in PfHDP resulted in food vacuole abnorma

146 carboxy-lobe of calmodulin with a calmodulin-binding domain in the C-terminus of TRPA1.

147 GG/RG domains are the second most common RNA binding domain in the human genome, yet their RNA-bindin

148 ymerase (RNAP) beta subunit is a part of RNA binding domain in transcription complex.

149 mab binds to both ActRIIA and ActRIIB ligand binding domains in a competitive manner at the critical

150 The two separate non-overlapping DNA binding domains in the ERCC1-XPF heterodimer jointly bin

151 the nucleotide-binding domain and substrate-binding domain) in response to adenine nucleotides and s

152 Antisera against AmOmpA or its predicted binding domain inhibits A. marginale infection of host c

153 nker connecting S6 and the cyclic-nucleotide-binding domain interacts directly with both the voltage-

154 l states of the trimer wherein each receptor-binding domain is either tightly packed at the membrane-

155 We show here that while the central DNA binding domain is essential for anchoring at parS, this

156 ent, and that the region adjacent to the DNA-binding domain is pivotal to its homo-trimerization.

157 4 isoform, ACTN4 (Iso), that loses its actin-binding domain is still capable of potentiating a GRE re

158 n domains, amide exchange throughout the DNA-binding domains is decreased as if the entire domain is

159 ges over classic methods for determining RNA-binding domains: it produces proteome-wide, high-resolut

160 on CDF1, as mutations of the N-terminal TPL binding domain largely impair the ability of CDF1 protei

161 The RARbeta ligand-binding domain (LBD) and DNA-binding domain (DBD) are ph

162 GluA2 AMPA subtype glutamate receptor ligand-binding domain (LBD) dimers to characterize a natural pr

163 The presence of intact ligand-binding domain (LBD) ensures the strict androgen-depende

164 he crystal structure of the PPARgamma ligand-binding domain (LBD) in complex with VSP-51, which revea

165 aphy reveals that SJB7 resides in the ligand-binding domain (LBD) of hPXR, interacting with the AF-2

166 the DNA-binding domain (DBD) with the ligand-binding domain (LBD) via a mix of positively charged and

167 Agonists bind to the ligand-binding domain (LBD) which is arranged as a dimer of dim

168 pe-specific residues in the PPARdelta ligand-binding domain (LBD).

169 at many bacterial chemoreceptors have ligand-binding domains (LBD) of the dCACHE family, a structure

170 amics simulations of GluN1 and GluN2B ligand binding domains (LBDs) of NMDARs to investigate these ef

171 Nucleotide-binding domain leucine-rich repeat (NLR) proteins functi

172 study, we explore the role of the nucleotide-binding domain leucine-rich repeat containing receptor f

173 In mice, specific nucleotide-binding domain, leucine-rich repeat-containing family, a

174 ory proteins (NAIPs) activate the nucleotide-binding domain, leucine-rich repeat-containing family, C

175 ty; however, the plant can evolve nucleotide-binding domain-leucine-rich repeat domain-containing pro

176 distant sites on a DNA molecule with the DNA-binding domains located at each end of its strut-like st

177 In addition, Actr10 lacking the dynactin binding domain maintains its ability to bind mitochondri

178 w that DNA bricks with longer, 13-nucleotide binding domains make it possible to self-assemble 0.1-1-

179 Proteins containing a methyl-CpG-binding domain (MBD) bind methylated DNA and interpret e

180 DNA cytosine methylation and methyl-cytosine binding domain (MBD) containing proteins are found throu

181 Like other members of the methyl-CpG-binding domain (MBD) family, MeCP2 functions through the

182 In the presence of the MeCP2 methyl-CpG-binding domain (MBD), however, DNA methylation of decoys

183 TP7B, and the group of the first three metal-binding domains (MBD1-3) are central to the activity reg

184 omain of eIF4G plus an adjacent probable RNA-binding domain mediate translation initiation.

185 three of the GW/WG repeats in its Argonaute-binding domain: motif-1, motif-2, and the hook motif.

186 n cells stably expressing a PR-A or PR-B DNA-binding domain mutant (PRmDBD), P4-mediated transrepress

187 es or heterozygous males with an ERalpha DNA-binding domain mutation knocked in (WT/KI) to produce WT

188 structured domains: an N-terminal nucleotide-binding domain (NBD) and a C-terminal substrate-binding

189 able docking and undocking of its nucleotide-binding domain (NBD) and substrate-binding domain (SBD).

190 el predicted that a region in the nucleotide-binding domain (NBD) of DnaK interacted with a region in

191 from its inhibitory position; the nucleotide-binding domains (NBDs) form a "head-to-tail" dimer upon

192 coupling ATP-driven movements of nucleotide binding domains (NBDs) to the transmembrane domains (TMD

193 positive allosteric modulators of the ligand-binding domain of (S)-2-amino-3-(3-hydroxy-5-methylisoxa

194 exhibits an amino acid exchange in the auxin-binding domain of ABP1.

195 -3 was found to interact with the nucleotide-binding domain of ATP7B, thus physically coupling the do

196 cture of ciA-C2 in complex with the receptor-binding domain of BoNT/A1 (HCA1) at 1.68 A resolution.

197 The CP-binding domain of CARMIL consists of the CP-interaction

198 The GTP-binding domain of CrSEPT purified as a nucleotide-free m

199 y phosphorylating the phosphoinositide- (PI) binding domain of Daple, Akt abolishes Daple's ability t

200 t has similarities to the cysteine-rich zinc-binding domain of DnaJ chaperones.

201 that She1 directly contacts the microtubule-binding domain of dynein, and that their interaction is

202 ons is dependent on joint binding to the DNA binding domain of ERCC1 and XPF.

203 ides that interact specifically with the DNA binding domain of ERG.

204 The eponymous DNA-binding domain of ETS (E26 transformation-specific) tran

205 was obtained of 1b when bound in the ligand binding domain of GluK1.

206 e binding of d(GAC)7.d(GAC)7 with the Zalpha-binding domain of human adenosine deaminase acting on RN

207 Comparative modeling of the DNA-binding domain of human HSF1 facilitated the prediction

208 SARS-CoV PLpro in complex with the principle binding domain of human ISG15 (hISG15) and mouse ISG15s

209 ic homeostasis suggest that the RGD integrin-binding domain of IGFBP-1 may be a promising candidate f

210 The RGD integrin-binding domain of IGFBP-1, through integrin engagement,

211 -histidine replacement at residue 435 in the binding domain of IgG3 to FcRn increases the transplacen

212 ecular binding motif is connected to the p53 binding domain of MdmX by a conserved flexible linker th

213 of DISC1 C-terminal tail in complex with its binding domain of Ndel1.

214 e compound was shown to bind the minimal cap-binding domain of PB2 to inhibit the cap-snatching machi

215 d that AA binds to and stabilizes the ligand-binding domain of peroxisome proliferator-activated rece

216 acellular nanovesicles lysates using the Ras-binding domain of Raf also coprecipitates with ESCRT (en

217 report the crystal structures for the ligand-binding domain of RORgammat in both apo and ligand-bound

218 The actin-binding domain of Shot directly interacts with Actin-rel

219 affecting the coiled-coil domain or the DNA-binding domain of signal transducer and activator of tra

220 e tumor phenotype was dependent on the FBXW7-binding domain of sT, but not the sT-PP2A binding domain

221 action by rapamycin, truncation of the MyD88-binding domain of TACI, or B-cell-conditional mTOR defic

222 on of tau, which flanks the core microtubule-binding domain of tau, contributes largely to the format

223 us in Deltaras2 RAS2 interacted with the RAS-binding domain of the adenylate cyclase in vitro, and th

224 ly encoded probes consisting of the PtdIns4P-binding domain of the bacterial effector SidM.

225 , a portion of the previously described TBK1-binding domain of the gamma34.5 gene (D.

226 nce similarity with the extracellular ligand-binding domain of the human alpha7 nAChR, to investigate

227 and selective Nanobodies against the ligand-binding domain of the human EphA4 receptor.

228 steroidal ligands able to bind to the ligand-binding domain of the MR and recruit different co-regula

229 ucts lacking the entire extracellular ligand-binding domain of the receptor while retaining the trans

230 identified a novel missense mutation in the binding domain of the STAT3 protein in a patient with ND

231 ed on the source of the extracellular ligand binding domain of the subunit.

232 tein motif located at the border of the SMAD-binding domain of ZEB2 protein induces ribosomal pausing

233 wall of A. thaliana by targeting the starch-binding domains of A. thaliana starch synthase III to th

234 Here we report the binding domains of carbon dioxide and acetylene in a tet

235 flavin adenine dinucleotide (FAD)- and heme-binding domains of Cylindrospermum stagnale NOX5.

236 main to wedge apart the membrane and F-actin-binding domains of ezrin.

237 Crystal structures of the ligand binding domains of most of the phylogenetically widespre

238 We showed that the actin-binding domains of nesprin 1 were dispensable, whereas n

239 n also enables the identification of the RNA-binding domains of RBPs.

240 KEY MESSAGE: Starch binding domains of starch synthase III from Arabidopsis

241 pend on the integrity of the motor and lipid-binding domains of the protein.

242 echanisms by which missense mutations in DNA-binding domains of transcription factors can lead to aut

243 Although PfAP2-I contains three AP2 DNA-binding domains, only one is required for binding of the

244 augmented and that its highly conserved DNA binding domain or the human homolog PC4 is sufficient to

245 Combinatorial polyvalent contacts of histone-binding domains or readers commonly mediate localization

246 P (FK506-binding protein) and FRB (rapamycin-binding domain) pair and split GFP fragments.

247 Conversely, the PIH1D1 phospho-binding domain PIH-N is required for association with MR

248 The K-homology (KH) domain is a nucleic acid-binding domain present in many proteins but has not been

249 horter CD33m isoform lacking the sialic acid-binding domain produced primarily from the "LOAD-protect

250 ransferases (DNMTs) 3a and 3b and methyl-CpG-binding domain protein 2 (MBD2) to the Ankrd26 promoter.

251 The BER enzyme methyl-CpG binding domain protein 4 (MBD4) has been linked to the M

252 tify the PO membrane protein acyl-coenzyme A-binding domain protein 5 (ACBD5) as a binding partner fo

253 nding factor (CTCF) is an 11 zinc finger DNA-binding domain protein that regulates gene expression by

254 Mutations in its spike (S) protein receptor-binding domain (RBD), a key vaccine target, have been id

255 4 (DPP4) via the spike (S) protein receptor-binding domain (RBD).

256 onfiguration of Nth1's catalytic and calcium-binding domains relative to each other, thus stabilizing

257 f the tubulin dimer orientation and membrane-binding domain represents an essential step toward our u

258 catalytic site of the C-terminal nucleotide binding domain restored proper protein trafficking and c

259 ations to apply tension across the substrate binding domain (SBD) of heat shock protein 70 (Hsp70) to

260 ding domain (NBD) and a C-terminal substrate-binding domain (SBD), which are tethered by an interdoma

261 ucleotide-binding domain (NBD) and substrate-binding domain (SBD).

262 ional changes of single and native substrate-binding domains (SBD) of an ATP-Binding Cassette importe

263 of ERbeta (mERbeta2) with a modified ligand-binding domain sequence.

264 main and G3BP1 RNA (RRM) and ribosomal (RGG) binding domains showed that sigmaNS association and VF l

265 process is reproducible with three different binding domains specific to methicillin-resistant Staphy

266 Pathological Tau mutants lacking the vesicle binding domain still localize to the presynaptic compart

267 eracting region (LIR), but not its ubiquitin-binding domain, supported T cell proliferation.

268 TBK1 under certain conditions through a TBK1-binding domain (TBD), there was no direct impact of the

269 d knockin mice with a mutation in the TR DNA-binding domain that abrogates binding to DNA and leads t

270 on distinct surfaces of the Ska1 microtubule binding domain that disrupt binding to soluble tubulin b

271 ors sharing a structurally similar pheromone-binding domain that functions allosterically to regulate

272 gene 4 protein of phage T7 comprises a zinc-binding domain that recognizes a specific DNA sequence a

273 ymerase identified to date; it lacks two DNA-binding domains (the thumb domain and 8-KD domain) conse

274 ructs demonstrated that a portion of the ACh binding domain, the E loop, is a key determinant.

275 y converting a promiscuous natural human IgG-binding domain, the hyperthermophilic variant of protein

276 f DnaK, involving lobe IIA of the nucleotide binding domain, the inter-domain linker, and the beta-ba

277 inal angiopoietin domains to the Tie2 ligand-binding domain, the mechanisms for Tie2 activation are p

278 binds to these receptors via several lysine-binding domains, the specific interactions that occur ha

279 that TRIP8b binds the HCN cyclic nucleotide-binding domain through a 37-residue domain and the HCN C

280 F764 physically interacted with GR at ligand-binding domain through its KRAB domain, and both its phy

281 ing, and functional data have identified two binding domains through which propofol acts on the GABAA

282 electrophoresis, we coarsely mapped the CaM-binding domain to a site within the CPK28 J domain that

283 can be used to temporally recruit an F-actin binding domain to MT plus ends and cross-link the MT and

284 aches that use genotyping of the AHR1 ligand binding domain to screen for DLC sensitivity among avian

285 pre-complex, enabling its neighboring ligand binding domain to tightly clamp the two polypeptides tog

286 Therefore, adding protein-specific binding domains to DNA nanostructures can be used to rat

287 ple the extracellular regulatory and agonist-binding domains to the pore-forming trans-membrane domai

288 ach of the three candidate CENP-A nucleosome-binding domains (two on CENP-C and one on CENP-N) to CEN

289 rties, IL-10-based modeling predicts two DNA-binding domains, two amphipathic helices, and an in-plan

290 anching can indeed be detected using both Ub binding domains (UBDs) tested at endogenous levels.

291 intrinsic specificities of the AR and GR DNA-binding domains using a refined version of SELEX-seq.

292 , whereas nesprin 1alpha2, which lacks actin-binding domains, was crucial for postnatal viability, nu

293 specificity, and their specific reticulocyte-binding domains were mapped within their N-terminal regi

294 e critical helix 12 region of the ER hormone binding domain, where they are likely to be single allel

295 Anillin contains a RhoA-GTP binding domain, which autoinhibits the NLS and the neigh

296 ontrolled by two regulatory domains: the DNA-binding domain, which interferes with sliding when its r

297 bule motor kinesin-1 interacts via its cargo-binding domain with both microtubules and organelles, an

298 equires substantial reorientation of the DNA-binding domain with respect to the ATPase domains.

299 -terminal linker (IDL) that connects the DNA binding domain with the 9 amino acid C-terminal acidic t

300 ent occurs between the beta-catenin and p120-binding domains within the cadherin cytoplasmic tail.