ライフサイエンスコーパス: binding experiment

1 nt of a ligand in an equilibrium competition binding experiment.

2 ed through guanosine 5'-O-(thiotriphosphate) binding experiments.

3 mersome shell, as proven by selective lectin binding experiments.

4 odynamic, biosensing, or other thermodynamic binding experiments.

5 These conclusions were confirmed by coenzyme binding experiments.

6 ced by enzymatic assays and antigen-antibody binding experiments.

7 ceptors/channels/transporters in radioligand binding experiments.

8 to get the most out of valuable reagents in binding experiments.

9 zed by enzyme inhibition and NMR and Biacore binding experiments.

10 interpretation and design of protein-ligand binding experiments.

11 and E2F was also supported by independent TF binding experiments.

12 ociation constants were determined in direct binding experiments.

13 by sequence patterns discovered by in vitro binding experiments.

14 fibril assembly using chromatography and dye-binding experiments.

15 brane-based [(3)H]DPCPX and [(35)S]GTPgammaS binding experiments.

16 y two conceptually different sets of tweezer binding experiments.

17 fully displaced radiolabeled vasopressin in binding experiments.

18 n by using in situ hybridization and in situ binding experiments.

19 to be -6.5 kcal mol(-1) at pH 4.9 by vesicle binding experiments.

20 finity for neuropilin-1 based on competition binding experiments.

21 our three-dimensional structure and affinity binding experiments.

22 nsfected in human cell lines and by in vitro binding experiments.

23 nding of RcoLS20, as seen in competitive DNA binding experiments.

24 of in vitro biochemical analyses and in vivo binding experiments.

25 518 using small-angle neutron scattering and binding experiments.

26 was validated by immunoblotting and in vitro binding experiments.

27 inely used as probes for conducting in vitro binding experiments.

28 was shown by neutralisation and micro-array binding experiments.

29 onfirmed by surface plasmon resonance direct binding experiments.

30 ng GABAB receptors and performed competition binding experiments.

31 Anion binding experiments ((1)H NMR titrations, ESI-MS) reveal

32 n [(35)S]-tert-butylbicyclophosphorothionate binding experiments, (2) in electrophysiological experim

33 n [(35)S]-tert-butylbicyclophosphorothionate binding experiments, (2). in electrophysiological experi

34 In equilibrium and kinetic binding experiments [(3)H]RO6957022 showed high affinity

35 ere also synthesized and used in competition binding experiments against [(125)I-Tyr(4)]BBN in GRPR-p

36 Competition binding experiments against [(125)I-Tyr(4)]BBN were cond

37 Among the best candidates, in vitro binding experiments allowed identification of three nove

38 Significantly, the equilibrium binding experiments also indicate that, regardless of wh

39 ANS binding experiments and analysis of the CD data show tha

40 This conclusion was further supported by binding experiments and assessment of membrane lipid pac

41 We also use a combination of in vitro binding experiments and bioinformatics analysis to redef

42 DNA binding experiments and cell-based transcription studies

43 A with Sp1 was demonstrated through in vitro binding experiments and coimmunoprecipitation and is sup

44 d control cells was assessed in cell culture binding experiments and compared with that of microbubbl

45 experimentally validated by hsc-70 endosomal binding experiments and endosomal microautophagy assays.

46 Binding experiments and functional assays identified MD2

47 ding kinetics, without the need for repeated binding experiments and immobilizing the molecules.

48 nR in two crystal forms together with ligand binding experiments and in vivo studies.

49 Binding experiments and Laurdan generalized-polarization

50 Ligand blot analysis, C3 binding experiments and opsonophagocytosis assays identi

51 RBPmap was tested on high-throughput RNA-binding experiments and was proved to be highly accurate

52 ctroscopy and saturation transfer difference binding experiments) and ultimate hit validation by isot

53 In silico docking analysis, competition binding experiments, and downstream assays were used to

54 Equilibrium binding experiments are widely used for the accurate cha

55 transfer (BRET)-based saturation and kinetic binding experiments, as well as a high specific to nonsp

56 In competition binding experiments, atrial natriuretic peptide and brai

57 extensive nucleotide sequences identified in binding experiments based on their selection by a TF.

58 In chromatin binding experiments, bexarotene increased the occupancy

59 However, our SRAP-RNA binding experiments, both in vitro with recombinant prot

60 In direct binding experiments, bovine IF-2(mt) has a 25-fold great

61 y distinguished from full-length channels in binding experiments but do not form functional channels.

62 Real time binding experiments by surface plasmon resonance spectro

63 Real time binding experiments by surface plasmon resonance spectro

64 Real time binding experiments by surface plasmon resonance spectro

65 tes could not be predicted from in vitro DNA-binding experiments by using recombinant Alx3.

66 Competitive binding experiments carried out in solutions of intermed

67 Structural analyses and binding experiments comparing the wild-type furin propep

68 Both direct and displacement binding experiments concurred to define the following bi

69 Transient-state glucose binding experiments conducted in the presence of increas

70 Ab binding experiments conducted with an enzymatically degl

71 [(3)H]NMS ([(3)H]N-methylscopolamine) binding experiments confirm that LY2119620 does not comp

72 dent synaptosomal DA release and radioligand binding experiments confirmed correct expression and fun

73 Equilibrium binding experiments confirmed that C-terminal peptides d

74 In vitro binding experiments confirmed that CMG and/or Mcm2-7 had

75 In vitro binding experiments confirmed that recombinant DbpA prot

76 Equilibrium binding experiments confirmed that the truncated protein

77 Saturation binding experiments demonstrate reduced affinity of the

78 Radioligand binding experiments demonstrate that mutations in this r

79 ally, dynamic light scattering and gel shift binding experiments demonstrate that the ED interface pl

80 Binding experiments demonstrate that the Necl proteins p

81 These binding experiments demonstrate the potential of fluores

82 In vitro binding experiments demonstrated that activated Arl1p-GT

83 Molecular docking and TR-FRET GR competitive binding experiments demonstrated that ASI could bind to

84 Protein binding experiments demonstrated that intimin of types a

85 ever, our immunoprecipitation RT-PCR and RNA binding experiments demonstrated that IRP1, but not IRP2

86 Collagen binding experiments demonstrated that PP favors the form

87 DNA binding experiments demonstrated that PU.1 itself and El

88 Binding experiments demonstrated that the materials had

89 Solution binding experiments demonstrated that the transmembrane

90 Thus, direct binding experiments, dependence on heparan sulfate, and

91 Using binding experiments, electrophysiology and x-ray crystal

92 Erythrocyte binding experiments elucidated essential glycan contact

93 Competition binding experiments employing [3H]colchicine and purifie

94 In a competitive binding experiment, EpCAM aptamer generated a staining p

95 Here, we use 456 binding experiments for 119 regulators and 84 chromatin

96 Binding experiments for a model system of carbonic anhyd

97 well with affinities measured in radioligand binding experiments for both PAMs and NAMs with diverse

98 report crystallographic analyses and ligand-binding experiments for KAI2 recognition of karrikins.

99 We performed new binding experiments for p53 mutants and used DECOD to id

100 Binding experiments for TATA spacer relative to ATAT sho

101 the DNA binding affinities, and competition binding experiments further characterized the nature of

102 Quantitative epidermal growth factor (EGF)-binding experiments have shown that the EGF-receptor (EG

103 ift assays, together with ligand competition binding experiments, have demonstrated the inability of

104 In direct-binding experiments, HCV helicase bound DNA weakly at hi

105 Similar binding experiments identified a leucine-rich repeat wit

106 Glutathione S-transferase binding experiments identified an internal region of PIS

107 Moreover, binding experiments in mammalian cells show that the mut

108 Pulsed ultrafiltration binding experiments in phosphate buffer containing 0.15

109 Binding experiments in solution also confirm that one GN

110 (3)H]33 at the M2R, for instance, saturation binding experiments in the presence of the allosteric MR

111 Binding experiments in transfected cells also demonstrat

112 Here we perform quantitative binding experiments in vitro to determine the ligand req

113 d dopamine transporter (DAT)) in competitive binding experiments in vitro using cloned human transpor

114 ted ligand of TALL-1, which was confirmed by binding experiments in vitro.

115 ty of the mutant proteins is also evident in binding experiments in vivo.

116 Moreover, binding experiments in which one ligand was added after

117 In vitro and ex vivo autoradiography binding experiments in Wistar and in mGluR2 knockout and

118 Genome-wide binding experiments in zld mutants showed variable effec

119 cell surface levels of TMEM16A and cellular binding experiments indicate CLCA1 engages TMEM16A on th

120 rlin(S518D) adopt a closed conformation, but binding experiments indicate that a significant fraction

121 Genome-wide expression analyses and binding experiments indicate that Brg1 specifically coor

122 However, results of membrane binding experiments indicate that covalent linkage of th

123 Binding experiments indicate that neither SKP1 (S-phase

124 In fact, kinetic and binding experiments indicate that removal of the E-hook

125 Antibody inhibition and alpha6beta1 ligand binding experiments indicate that the egg integrin alpha

126 Radiolabeled galactose saturation binding experiments indicate that, like LeuT, vSGLT can

127 Kinetic binding experiments indicated a simple one-step binding

128 Competitive binding experiments indicated that the radiolabeled pept

129 se observations, in combination with surface binding experiments, indicated that trypsin indirectly a

130 dictions by transport kinetics and substrate-binding experiments, integrating the data on this single

131 fraction and a beta-glucan were monitored by binding experiments, ITC and DLS.

132 re reagents, but flaws in the design of many binding experiments limit the information obtained.

133 Nonetheless, in direct binding experiments, Mg(2+) replaced three Ca(2+) sites

134 Binding experiments on rat brain membranes and the purif

135 modulator binding modes through radioligand binding experiments on receptor mutants designed, on the

136 ased on high-throughput transcription-factor binding experiments or on comparative genomics.

137 m-exchange, solution scattering data and DNA-binding experiments, our studies reveal a light-sensitiv

138 enesis, nuclear magnetic resonance-monitored binding experiments performed for both H402 and Y402 var

139 Substrate binding experiments performed on purified MdtM demonstra

140 , and fluorescence resonance energy transfer binding experiments performed under equilibrium and kine

141 Grafted antibody binding experiments, performed under stringent condition

142 In vitro binding experiments presented here show that histone ace

143 Additional SAXS, DXMS, and dsRNA-binding experiments presented here support a model of co

144 Furthermore, real-time binding experiments provide no evidence for a more exten

145 Other binding experiments provided evidence for a conformation

146 In vitro binding experiments reveal a direct, robust interaction

147 Ligand-binding experiments reveal a much greater fraction of N5

148 Consistent with this model our in vitro binding experiments reveal optimal assembly of two wild-

149 Interestingly, DNA binding experiments reveal that the identity of the two

150 Surface plasmon resonance binding experiments revealed binding and dissociation of

151 The anion binding experiments revealed interesting difference in t

152 t the catalytic site, and ligand competition binding experiments revealed no competition between L685

153 In vitro protein-protein binding experiments revealed that >65% of these TF pairs

154 Binding experiments revealed that a subset of the BKV mu

155 CaM-binding experiments revealed that all five AtBTs are CaM

156 A series of in vitro DNA binding experiments revealed that POU1F1 binds to multip

157 Furthermore, membrane-binding experiments revealed that the basic linker regio

158 Ligand binding experiments revealed that the S186F protein had

159 Gel filtration and biosensor binding experiments revealed that, unlike host FcgammaRs

160 Modeling and binding experiments revealed these conformations to be p

161 Binding experiments show that alpha-COP and beta'-COP ha

162 Finally, DNA binding experiments show that CasA is essential for bind

163 Direct binding experiments show that CDK phosphorylation specif

164 ob1 is essential for optimal growth, and RNA binding experiments show that Dim2 increases Nob1 RNA af

165 Our in vitro binding experiments show that DNA-binding/dimerization d

166 Separate kinetic and binding experiments show that hTdp1 has a preference for

167 Moreover, binding experiments show that K(+) (but not Na(+)) incre

168 In vitro binding experiments show that MSP promotes oocyte mitoge

169 nteracts with full-length Mlp1p and in vitro binding experiments show that Nab2p binds directly to th

170 re, de novo Rosetta modeling and competitive binding experiments show that the acidic tip of the E. c

171 Binding experiments show that the affinity of the E2b co

172 Stoichiometric binding experiments show that the functional RNP complex

173 DNA-binding experiments show that the Ml proteins studied bi

174 Thermodynamic binding experiments show that the MLL1 Win peptide is pr

175 Ligand-binding experiments showed a good binding affinity betwe

176 increase the rate of ADP release; and direct binding experiments showed osmotic pressure to correspon

177 Binding experiments showed that a Y315A mutation alone s

178 The results of binding experiments showed that after chronic morphine t

179 Equilibrium metal binding experiments showed that AntR binds 2 equivalents

180 interaction assays in live cells and in situ binding experiments showed that Atgl and its protein act

181 Radioligand binding experiments showed that derivatizing the N-termi

182 ion and amplification binding assays and DNA binding experiments showed that ID1 binds selectively to

183 However, in vitro binding experiments showed that mutant ICP27 was able to

184 Co-immunoprecipitation and in vitro binding experiments showed that NPM associated with PKR.

185 DNA binding experiments showed that PcrA bound much more eff

186 In vitro DNA binding experiments showed that recombinant N-ATF6 beta

187 Binding experiments showed that several AMC compounds ha

188 Competition DNA binding experiments showed that the 5' and central regio

189 However, in vitro binding experiments showed that the H4 mutant proteins b

190 Binding experiments showed that the polymorphic OGG1 bin

191 Drug resistance profiling and drug binding experiments showed that the presence of both Ebr

192 In vitro binding experiments showed that the strength of the inte

193 f surface plasmon resonance-based, real-time binding experiments showed that while both proteins have

194 MHC-I heavy chain, consistent with in vitro binding experiments showing significantly reduced comple

195 bed is applicable to equilibrium competition binding experiments such as radioligand assays and fluor

196 The results of competitive binding experiments suggest that a common adhesin recogn

197 In vitro binding experiments suggest that the Gcn4p activation do

198 Solid phase binding experiments suggest that the unstructured N-term

199 Fluorescence anisotropy competition binding experiments suggest that TWINKLE has more than o

200 Competitive binding experiments suggest that Zn and Cd share the sam

201 Inhibition and direct binding experiments suggest that, during the first half-

202 Mixed binding experiments suggested that gelatin, fibronectin,

203 Additionally, in vitro binding experiments supported the notion that the C term

204 However, in [(3)H]ryanodine binding experiments, the Ca(2+)-dependent activation and

205 Confirmed by mutagenesis and in vitro binding experiments, the novel consensus allowed for the

206 We find that in both saturation and kinetic-binding experiments, the Org 27569 and PSNCBAM-1 appeare

207 In saturation binding experiments, the three radioligands exhibited di

208 ral specificity in surface plasmon resonance binding experiments: The L-protein ligand bound only to

209 lography, molecular dynamics simulations and binding experiments to characterize the protocadherin 15

210 ssion profiling, and microfluidics-based DNA binding experiments to determine the direct and indirect

211 5-trisphosphate accumulation and radioligand binding experiments to determine the impact of receptor

212 Mathematical modeling of EGF-binding experiments to different conformational mutants

213 e anisotropy, functional assays, and Biacore binding experiments to examine the effects of mutations

214 valuate the feasibility of using competition binding experiments to identify specific lipid-protein i

215 and antibodies to HSPGs were used in in situ binding experiments to identify which HSPGs bound CXCL8.

216 ing complex antibody mixtures and in antigen-binding experiments to understand the contribution of do

217 study uses theory, as well as simulations of binding experiments, to test the validity of the three i

218 In competition binding experiments two derivatives (13 and 14) emerged

219 NADH in these preparations, we conducted the binding experiments under anoxic conditions in a special

220 Binding experiments under conditions at which hCXCL1 exi

221 Radioligand binding experiments using [(3)H]MPEP revealed that these

222 Equilibrium binding experiments using a judiciously chosen panel of

223 Equilibrium binding experiments using a panel of well-characterized

224 Competitive binding experiments using a series of ligands including

225 Previous in vitro binding experiments using bacterially expressed HDAg sho

226 me flow cytometry and competition inhibition binding experiments using cell surface CD16a.

227 Detailed binding experiments using cells expressing ALK or the re

228 Binding experiments using either endogenous p21 mRNA or

229 PSMA targeting was analyzed in vitro by cell-binding experiments using flow cytometry, autoradiograph

230 DNA binding experiments using gel-shift and ChIP assays demo

231 Binding experiments using heparin-Sepharose gel demonstr

232 Binding experiments using phosphoinositide-containing ve

233 Binding experiments using protein fluorescence confirm t

234 ymogens in a systematic manner, we performed binding experiments using recombinant proelastases CELA2

235 Equilibrium binding experiments using saturating hPRLbp concentratio

236 Neutral-sugar analysis and lectin binding experiments using succinylated concanavalin A, a

237 Real-time binding experiments using surface plasmon resonance show

238 Real-time binding experiments using surface plasmon resonance spec

239 Binding experiments using the isolated GAF domain of EI(

240 Competitive binding experiments using unlabeled and 125I-M12A genera

241 rform in vitro catalytic activity assays and binding experiments using ZAP-70 proteins purified from

242 Binding experiments, using fluorescent liposomes, confir

243 In competition-binding experiments, V2 outcompetes SGS3 for substrate d

244 Direct binding experiments, via isothermal titration calorimetr

245 rs in the striatum as measured by D1- and D2-binding experiments was greatly diminished in the mutant

246 Through kinetic radioligand binding experiments, we characterized mutant receptors s

247 In combination with fluorescence binding experiments, we conclude that triclosan binds to

248 In further competition binding experiments, we identified 12 compounds with aff

249 s simulations, mutagenesis, and A1-GpIbalpha binding experiments, we identified a network of salt bri

250 ional analysis, and fluorescent polarization binding experiments, we identify here three structural m

251 Using scoC-lacZ fusions and DNA-binding experiments, we show here that scoC is directly

252 st two-hybrid assays followed by biochemical binding experiments, we show that the region in CAPS1 co

253 cations from dissociation of this dimer, DNA binding experiments were carried out using an SS crossli

254 Protein folding and TolA binding experiments were combined with real-time NMR spe

255 Binding experiments were conducted by fluorescence spect

256 Catch and release competitive binding experiments were done by NMR for the cation-carb

257 In vitro saturation binding experiments were performed for (99m)Tc-TCP-1 in

258 Cyanide-binding experiments were performed to assess trans effec

259 Surface plasmon resonance binding experiments were performed using immobilized gam

260 ac-2 in host-pathogen interactions, solution binding experiments were performed using surface plasmon

261 Enzyme-substrate and enzyme-inhibitor binding experiments were performed using water-ligand ob

262 (125)I-STa-binding experiments were performed with intestinal mucos

263 Meat binding experiments were performed with two technical TG

264 In addition, the SPR binding experiments were qualitatively simulated, confir

265 ensing mechanism, optical and potentiometric binding experiments were used to characterize the stoich

266 r recognition between VEGF and this aptamer, binding experiments were used to show that the HBD contr

267 s interaction are determined in a saturation binding experiment, where increasing concentrations of p

268 s is further supported by a series of direct binding experiments, which clearly demonstrate a high af

269 Binding experiments with [(3)H]N-methylscopolamine at th

270 Receptor binding experiments with [3H]MK-801 showed significant u

271 tein receptor (sLDLR) was employed in ligand binding experiments with a fluorescently tagged variant

272 on of vancomycin was achieved in competitive binding experiments with a horseradish peroxidase-vancom

273 To explain this phenomenon, we performed binding experiments with a peptide construct of the tail

274 e evaluated assay performance by competitive binding experiments with a series of known ligands and a

275 Binding experiments with alkyl-transfer-active and -inac

276 odeling and isothermal titration calorimetry binding experiments with an engineered PG9 mutant sugges

277 l into question many of the past kinetic and binding experiments with ATCase with nucleotides as the

278 Meat binding experiments with beef and pork were performed us

279 Competition binding experiments with both MCHR isoforms, a series of

280 Competitive in vivo binding experiments with BR55 were performed in knock-ou

281 Binding experiments with circularly permutated DNA probe

282 Binding experiments with CTRC revealed that (i) inhibito

283 However, UV-vis, EPR, NIR MCD, and ligand binding experiments with ferrous and ferric Ns H-NOX ind

284 Equilibrium binding experiments with HeLa S(3) cells indicate that r

285 Binding experiments with heterologously expressed repeat

286 molecules allows one to perform competition binding experiments with high sensitivity while avoiding

287 Binding experiments with immobilized vitronectin suggest

288 Binding experiments with LA3-5 of LDLR and CR16-18 showe

289 application of this probe by performing NMR binding experiments with Lck and Src kinases and utilize

290 2 N-terminal region were studied in in vitro binding experiments with purified gH/gL and in cell-cell

291 Comparative in vitro binding experiments with purified proteins demonstrated

292 In vitro binding experiments with purified virus polymerase and N

293 Binding experiments with radioactive (45)Ca(2+) demonstr

294 d and characterized by in vitro displacement binding experiments with rat brain membranes, in vitro a

295 The assay was tested in competitive binding experiments with substrates and products of KMO

296 spective Ki values determined in radioligand binding experiments with the purified receptor.

297 Binding experiments with the von Willebrand factor A3 do

298 SRA binding experiments with this domain gave negative resul

299 al to the mica substrate through qualitative binding experiments with Trichosanthes kirilowii aggluti

300 In binding experiments with wild-type (WT) sLDLR, FRET-depe