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1 ontaining aromatic amino acids, the caveolin-binding motif.
2 use the predicted protein contains a Myb DNA binding motif.
3 846053 affects a putative intronic NFAT5 DNA binding motif.
4 e tandem Tudor domain and masks its H4K20me2 binding motif.
5 lation site and flanks the hydrophobic Ezrin-binding motif.
6 ly potent inhibitors having a sulfamide zinc-binding motif.
7 xtended tail domain with an additional actin-binding motif.
8 ia by a mechanism of action using a lipid-II-binding motif.
9 were strongly enriched for the consensus GR-binding motif.
10 ged preference for a low-affinity, secondary binding motif.
11 natal thymic epithelia and defined the Foxn1 binding motif.
12 group via an aromatic box, a typical choline-binding motif.
13 but also afforded discovery of a novel CTCF binding motif.
14 a novel small ubiquitin-like modifier (SUMO) binding motif.
15 e allelic imbalance from the disruption of a binding motif.
16 alf and PIFs' conserved active-phytochrome B binding motif.
17 binding sites, based on the discovery of its binding motif.
18 dominantly at W-box elements, the known WRKY binding motif.
19 4 E3 ligase requires a highly conserved zinc-binding motif.
20 inding through an Arg-Gly-Asp (RGD) integrin-binding motif.
21 s by a single point mutation in the caveolin-binding motif.
22 imately 800) with no high-throughput-derived binding motifs.
23 fic domain and Kv7 channel 1-5-10 calmodulin-binding motifs.
24 enhancers do not encode canonical NF-kappaB binding motifs.
25 f Clostridium difficile has intact LytM zinc-binding motifs.
26 shoot compared with models based on known TF binding motifs.
27 ated R domain contains nine different 14-3-3 binding motifs.
28 fluorescent proteins (FPs) fused with Zn(2+)-binding motifs.
29 ndidate binding sites and discover potential binding motifs.
30 binding was obtained at two canonical STAT5 binding motifs.
31 ociate with STAT5 at sites lacking bona fide binding motifs.
32 Gli3 has multiple weak SPOP binding motifs.
33 ol for characterizing CB1R allosteric ligand-binding motifs.
34 sting the existence of common RGD-containing binding motifs.
35 ctly alter recognizable transcription factor binding motifs.
36 o accurately infer monomeric and homodimeric binding motifs.
37 on inadequate knowledge of cell-specific DNA binding motifs.
38 helices were replaced by synthetic membrane-binding motifs.
39 key residue difference in the consensus GTP-binding motifs.
40 n with the DNA minor groove that flanks PU.1-binding motifs.
41 odifiers that bind RNA without canonical RNA-binding motifs.
42 be related to their different C-terminal PDZ binding motifs.
43 istinct combinations of transcription factor-binding motifs.
44 , we showed that several residues in the RNA-binding motif 2 interact with the N-terminal region of t
45 ruption of the implicated intramolecular RNA-binding motif 2-RS domain interaction impairs both the d
47 NA recognition motif (RRM) of one of the RNA binding motif-20 alleles was floxed and that expressed t
50 ific binding of the three proteins to an Rsm-binding motif (5'CANGGANG3') encompassing the translatio
51 tivity, and an extended tail with tail actin-binding motif, allow it to play an important role in sta
52 e, TRPC4/5 channels contain a C-terminal PDZ-binding motif allowing for binding of the scaffolding pr
53 ed flat free energy landscape containing all binding motifs allows determination of the ligand mechan
57 flanked by a C-terminal helix-turn-helix DNA-binding motif and a divergent N-terminal receiver domain
58 tes with Rad18 directly via a consensus USP7-binding motif and can disassemble Rad18-dependent poly-u
59 uted cyclopentyl amide as a preferred FKBP51-binding motif and elucidated its binding mode to provide
60 We have identified an hnRNP E1 consensus-binding motif and genomically resolved a subset of genes
61 erizes the binding kinetics of the consensus-binding motif and hnRNP E1, its various K-homology (KH)
62 enetic variation that disrupts the consensus binding motif and its methylation is often associated wi
63 rotective effect of EphB2 depends on its PDZ-binding motif and the presence of neuronal activity but
65 se data enabled the discovery of subdominant binding motifs and an integrative analysis quantifying t
66 , we identify that PrimPol possesses two RPA-binding motifs and ascertained the key residues required
67 evolution," to reflect the diversity of both binding motifs and binding motif transitions and the fac
68 ractions is crucial to understanding protein binding motifs and cellular function, that is, an intera
69 referentially in the direct vicinity of NFAT-binding motifs and in a distinct orientation to them.
70 the availability of large scale data for RBP binding motifs and in vivo binding sites results in the
71 inding, burst-like expression, degeneracy of binding motifs and massive regulatory rewiring during ev
72 ry data (e.g. presence/absence of mutations, binding, motifs and epigenetic marks) and continuous dat
73 mbrane protein that contains the WD40 domain-binding motif, and disrupts its normal intracellular tra
74 in the identification of seven novel Mg(2+)-binding motifs, and all RNA structures in the PDB were s
75 g sites within enhancers containing multiple binding motifs, and allows for the analysis of in vivo b
76 e virus were enriched for HLA class I and II binding motifs, and constituted both species-specific (R
77 ription factors relevant to the CRM or their binding motifs, and is thus more widely applicable than
78 in vivo, identifies export-promoting ALYREF-binding motifs, and reveals CstF64- and PABPN1-mediated
80 ion in the acetyllysine binding site, common binding motifs, and unusual interactions (e.g., the repl
81 he conserved residues in the putative cyclin-binding motif are important for protein expression, prot
82 t existing analysis methods require that the binding motifs are enriched in the population relative t
83 C terminus of VP1, a position where integrin binding motifs are found in some other picornaviruses.
84 we find that particular transcription factor binding motifs are intrinsically biased toward the gener
86 t the notion that the distinct alignments in binding motifs are part of a critical regulatory strateg
88 rtance of regulatory syntax, as noncanonical binding motifs are typically disregarded by enhancer det
90 midazoles with a rigidized 7-azaindole hinge binding motif as a new structural class of EGFR inhibito
97 e ACGT motif (Box2) rather than by the G-Box binding motif (Box1) in the vegetative phase of developm
98 but not of a variant lacking the periplakin binding motif, BTN3A1Deltaexon5, restored gammadelta T c
99 s motor domain contains conserved nucleotide binding motifs, but is divergent in sequence ( 35% ident
100 f the flexible linker and the intramolecular binding motif by assuming the flexible linker behaves as
101 ariant lies within the consensus SH3 protein-binding motif by which SHANK2 may interact with post-syn
102 demonstrate that local transcription factor binding motifs can be identified from a network trained
105 n structure analysis, further reveal how HLA-binding motifs change with peptide length and predict ne
106 Isolated deletions of the canonical GATA1 binding motif completely abrogated binding of the cofact
108 threonine for alanine in the C-terminal PDZ-binding motif conferred DAG sensitivity to the channel.
109 re, bioinformatics data, showing key citrate-binding motifs conserved across a broad range of PNPase
110 XI binding, which identified a series of FXI binding motifs containing the signature Asp-Phe-Pro (DFP
111 base pair (bp) deletion within IQ calmodulin-binding motif-containing protein-1 (IQCB1), the gene tha
113 he presence of transcription factor (TF) DNA binding motifs correlated with specific TF activity duri
116 ng nascent transcript RNA-seq, ChIP-seq, and binding motif datasets from lipid A-stimulated macrophag
118 oma and glioblastoma cell lines in a PDZ.PDZ binding motifs-dependent manner, but the cellular partne
121 The conformation of the prodomain integrin-binding motif differs in the presence and absence of int
122 t, despite the presence of putative cytokine-binding motifs, does not detectably interact with pathwa
123 s containing one or more double-stranded RNA binding motif (dsRBM) that play important roles in small
124 uring a tandem array of two highly conserved binding motifs, each comprising a 24-residue sequence RL
125 on, we show that a peptide comprising the ET binding motif (EBM) of MLV IN can disrupt the cognate in
126 scriptomic profiles and transcription factor binding motifs enabled us to construct a regulatory netw
129 ion pattern, identified transcription factor binding motifs enriched in each cluster, and generated a
133 gen residues gamma390-396 comprise the major binding motif for FXIII-A2B2 Compared with gammaA/gammaA
135 l cases are predicted to disrupt a canonical binding motif for the hematopoietic transcription factor
136 ripts contain a disproportionate amount of a binding motif for the quaking RNA binding protein, a seq
137 e identify and experimentally define a novel binding motif for the SOS transcriptional repressor LexA
141 dvance, the utilization of the corresponding binding motifs for fast and robust quantitative chemosen
142 gions are enriched for clusters of consensus binding motifs for HOX, PBX, and MEIS, and many display
143 hromatin regions, which demonstrate enriched binding motifs for inducible factors and correlate with
144 associated peaks were enriched for consensus binding motifs for NKX2-1, LHX, and SOX transcription fa
145 n, characterized by enrichment for consensus binding motifs for Nr4a and NFAT transcription factors.
146 , our computational analysis discovered that binding motifs for RUNX and CREB1 are found preferential
149 s characterized by a precise organization of binding motifs for the Sertoli cell reprogramming factor
150 reast and endometrial cancer and enriched in binding motifs for the transcription factor FOXA1, which
152 anscription factors (TFs), and enrichment of binding motifs for these TFs in alphaTC1/betaTC6 cis-reg
153 lysis of SAMHD1 identifies a putative cyclin-binding motif found in many cyclin-CDK complex substrate
155 core of MbIV resembles the tetrapeptide HCF-binding motif (HBM) found in many HCF-interaction partne
156 vitro evolution identify consensus hnRNP A1 binding motifs; however, such data do not reveal how sur
158 ivities were more likely to enrich for miRNA binding motifs; (iii) expression levels of these genes a
161 e variants or deletion of the C-terminal PDZ-binding motif in CaV1.3L induced aberrant dendritic spin
162 e M18BP1 motif resembles a CENP-A nucleosome binding motif in CENP-C, and we show that CENP-C compete
163 on of the glycosyltransferase-like metal ion binding motif in H3 greatly diminished its binding to UD
165 mmary, we have identified a unique substrate-binding motif in NleE and OspZ that is required for the
170 We identify a Lys-Gly-Glu (KGE) integrin-binding motif in the FVIIa protease domain that is requi
171 , the absence of a conserved ephrin receptor-binding motif in the MojV attachment glycoprotein (MojV-
173 II (CaMKII) strongly interacts with a novel binding motif in the N-terminal domain of CaV1 LTCC alph
177 ositions nucleosomes on top of adjacent Ume6 binding motifs in a highly predictable and reproducible
178 Finally, by integrating transcription factor binding motifs in a machine learning framework, we ident
180 ese echinoderms and that the targets and the binding motifs in associated cis-regulatory sequences ar
184 arch reveals occurrences of protein and drug binding motifs in the HERV RNA ensemble that do not occu
185 nd Taz (transcriptional coactivator with PDZ binding motif) in tissue development, homeostasis, and r
186 evolved under selection pressure to encode a binding motif innately capable of recognizing and neutra
187 rotein, demonstrating that ataxin3's p97/VCP-binding motif interacts with the inter-lobe cleft in the
188 esidues 483 and 484, located within the Alix-binding motif involved in virus budding, as major contri
193 TAZ (transcriptional coactivator with PDZ binding motif) is a transcriptional coactivator and end
195 oding an L53F protein variant within the ATP-binding motif, is prioritized as the candidate at the lo
198 ) and sodium channels possess homologous CaM-binding motifs, known as IQ motifs in their C termini, w
200 , Oxygen and Voltage sensing 2 (LOV2) flavin-binding motif located within the N-terminus of the photo
201 n a collection of known transcription factor binding motifs, many bioinformatics methods have been pr
202 ed a high-resolution structure of WHAMM's MT-binding motif (MBM) assembling around MTs using cryo-ele
203 diimide (PDI) unit and two triazolium anion-binding motifs, mechanically bonded with two smaller iso
204 e observed that SAMHD1 mutants of the cyclin-binding motif mislocalized to a nuclear compartment and
205 ing conservation of the transcription factor-binding motif (motif-based) are shown to substantially o
209 n binding to LRP1 based on the proposed LRP1 binding motif of 2 lysine residues separated by about 21
211 red via the BIR3 domain of cIAP1 and the IAP-binding motif of C9b, but did not require proteolytic cl
213 A2, which can become associated with the PDZ-binding motif of EphB2 through PDZ domain-containing pro
217 SNX27 binds directly to the C-terminal PDZ-binding motif of PTHR, wiring it to retromer for endosom
218 es an amino acid substitution in the calcium-binding motif of the extracellular cadherin (EC) domains
220 lity mass spectrometry, clearly indicating a binding motif of two partially overlapping diarylviologe
222 epigenetic network selectively enriched for binding motifs of a transcription factor cohort expresse
225 s, and their promoters were enriched for the binding motifs of TFAP2 (which was identified in promote
226 tion that enlists both of the N-terminal RNA-binding motifs of the protein with separate surfaces of
227 pressed growth plate genes, and enriched for binding motifs of transcription factors with roles in ch
228 rther NOE analysis provided a unique pyrrole binding motif, offering accurate substrate positioning w
229 o-box domain (PBD) of PLK1 interacted with a binding motif on MLL5 (Thr887-Ser888-Thr889), and this i
231 scovery of oncogenic activation of RBMY (RNA-binding motif on Y chromosome), which is absent in norma
232 g strategy that incorporates a serum protein binding motif onto a covalent side-chain staple and appl
234 created a mutant of Hsp93 affecting its ClpP-binding motif (PBM) (Hsp93[P-]), which is essential for
238 cular surface and a conserved "lock and key" binding motifs previously observed to mediate nectin/nec
239 ning octamer-binding protein (NONO), and RNA binding motif protein 14 (RBM14), all reported to be com
240 ell as in cellular mRNAs, is mediated by RNA-binding motif protein 15 (RBM15) and its paralogue RBM15
242 us missense mutations were identified in RNA-binding motif protein 20 (RBM20), a spliceosome protein
243 several cardiac splice factors, such as RNA-binding motif protein 20 and SF3B1, not only provided im
245 associates with the core splicing factor RNA binding motif protein 39 (RBM39) and localizes to nuclea
246 sulam promotes the recruitment of RBM39 (RNA binding motif protein 39) to the CUL4-DCAF15 E3 ubiquiti
247 nd instead define it as an extended Class II binding motif PXXPXRpXR, where additional positive charg
248 ted in multiple key residues in the receptor-binding motif (RBM) of RBD and demonstrated their strong
249 protein that regulates FtsZ, and its cognate binding motifs (RBMs) in defining the specific region of
250 lations and measurements, the intramolecular binding motif reduces the apparent affinity of p53 for M
253 Mutational analysis of the trailer HSPA8 binding motif revealed that this interaction is essentia
255 hannel of the 14-3-3 dimer, with both 14-3-3 binding motifs simultaneously participating in protein a
257 ressed genes often lacking canonical Tcf DNA binding motifs, suggesting a novel mode of direct repres
258 ormation-based analysis of the two homologs' binding motifs suggests a role for dynamic coupling in P
260 tion of transcriptional coactivator with PDZ binding motif (TAZ) and Yes-associated protein (YAP) pro
261 AP) and transcriptional coactivator with PDZ-binding motif (TAZ) are related mechanosensory proteins
262 induces transcriptional coactivator with PDZ-binding motif (TAZ) expression, which is required for os
263 AP) and transcriptional coactivator with PDZ-binding motif (TAZ) in mediating mechanotransduction and
264 P) and transcriptional co-activator with PDZ-binding motif (TAZ), are required for the generation of
267 the recently proposed tetracysteine-arsenic-binding-motif technology to detect and quantitatively ch
268 AMP with its main chain atoms, a nucleotide-binding motif that appears unique to eukaryotic ADPGKs.
271 ys enabled identification of a SigG promoter-binding motif that was supported in vivo by reporter stu
272 within the TE, we identified a module of TF-binding motifs that cooperatively enhanced gene expressi
273 r ALYREF binding sites and identified ALYREF-binding motifs that promote nuclear export of intronless
274 We functionalize these polymers with RNA-binding motifs that sequester polyadenine-containing nuc
276 d was developed to identify disease-specific binding motifs through integration of bacterial display
277 e RNAs (sgRNAs) integrated with up to 16 MS2 binding motifs to enable robust fluorescent signal ampli
278 ated S-arylation that exploits natural metal-binding motifs to ensure high site selectivity for a pro
279 ctionalities, as the possibility to identify binding motifs, to cluster aptamer families or to compar
280 ect the diversity of both binding motifs and binding motif transitions and the facilitation of their
281 e DNA segments are typified by consensus p63 binding motifs under purifying selection and are associa
282 ively, and are indicative of a change in the binding motif upon replacement of the ligand (GDP versus
285 ma' variant lacking the gammaC alphaIIbbeta3-binding motif was more reactive with alphaIIbbeta3 than
286 , we found that the DAT carboxy-terminal PDZ-binding motif was required for DAT recycling and exit fr
288 isclosed TAFIa inhibitors having a urea zinc-binding motif were used as the starting point for the de
289 ely or independently, and AP1, ETS, and RUNX binding motifs were enriched in the accessible chromatin
290 tion determinants, including a predicted PDZ binding motif, which are critical for its normal membran
291 ural analysis allow us to propose a novel UQ-binding motif, which is completely different compared wi
292 l3 carries both iron-sulfur cluster and zinc-binding motifs, which mediate interactions with Pol31, a
293 ciated peaks are enriched for Zic1 consensus binding motifs, while Zic1-bound peaks are also enriched
294 integrates a database of more than 65 000 TF binding motifs with tools to easily and efficiently scan
298 protein/Transcriptional coactivator with PDZ-binding motif, YAP/TAZ) and late (alpha-smooth muscle ac
299 VDR-BVs are enriched in consensus RXR::VDR binding motifs, yet most fell outside of these motifs, i
300 we employed peptide arrays based on zDHHC AR-binding motif (zDABM) sequences of synaptosomal-associat
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