ライフサイエンスコーパス: binuclear

1 being bridged by AsO4 bound in a monodentate binuclear (2)C complex (chain model).

2 incubation with a synthetic precursor of the binuclear [2Fe] subcluster, namely: [NEt4]2[Fe2(adt)(CO)

3 We further demonstrate that binuclear acinar cells are terminally differentiated aci

4 us of Ag is evident in the EPR signal of the binuclear active site observed upon reduction with CO, i

5 n spectroscopy and extended it to the entire binuclear active site of an oxygen-tolerant [NiFe] hydro

6 the progenitor RAPTA-C anticancer drugs, the binuclear agents neither arrest specific cell cycle phas

7 notion for a radical mechanism as well as a binuclear alpha-hydrogen abstraction pathway being opera

8 2 Nb}2 (mu2 -CH)(mu2 -H)(mu2 -Cl)] (3) via a binuclear alpha-hydrogen elimination.

9 activator CuIBr/TPEN existed in solution as binuclear and mononuclear complexes in equilibrium but a

10 Fusion of nuclei in binuclear and polynuclear microspores occurs spontaneous

11 rates triads, dyads, and monads that contain binuclear and polynuclear microspores.

12 One binuclear and six tetranuclear clusters are arranged, ma

13 Moreover, approximately 42% of binuclear and tetraploid cells assemble aberrant spindle

14 on-sulfur clusters, four to five (one or two binuclear and three tetranuclear) could be detected by E

15 ycle involving initial oxidation of Au(I) to binuclear Au(II)-Au(II) complexes by Selectfluor, follow

16 We propose binuclear Au(II)-Au(II) complexes to be key intermediate

17 We report that binuclear benzo[h]quinoline-ligated Ni(II) complexes, up

18 al adsorption complexes, namely inner-sphere binuclear bidentate.

19 group 4 "constrained geometry" catalysts and binuclear bisborane and bisborate cocatalysts have been

20 and arsenite exclusively formed monodentate-binuclear ("bridging") complexes (R(As-Fe) = 3.31-3.34 A

21 g DFT computational analyses, and involves a binuclear C-H bond-activation process.

22 repositories, where the predominance of the binuclear Ca(2+) complex, which is a precursor of variou

23 While the structural similarity of the binuclear calcium-binding sites in anthrax protective an

24 intense proliferative burst of predominantly binuclear cardiomyocytes.

25 with the phosphate group of AMP, implying a binuclear catalysis.

26 mer structures can be obtained by using such binuclear catalyst/cocatalyst systems.

27 Furthermore, the binuclear catalysts exhibit enhanced AO tolerance and en

28 t herein a study of the reaction pathway for binuclear CcrA from Bacteroides fragilis using density f

29 Binuclear cell nuclei combine their genomes on a single

30 esis of mononuclear cells contributes to the binuclear cell pool, whereas enclosure of entire mitotic

31 ophans are localized relatively far from the binuclear center (30-60 A); therefore, oxidation probabl

32 both the pump loading site (PLS) and to the binuclear center (BNC) are thermodynamically driven by e

33 coupled to the reduction of the active site binuclear center (BNC).

34 e high-pH side of the membrane each time the binuclear center active site is reduced.

35 During turnover, the binuclear center apparently shuttles via a metastable bu

36 bed by the reduction of the heme d/heme b595 binuclear center at the active site.

37 electron reduction of dioxygen to water in a binuclear center comprised of a high-spin heme (heme a(3

38 ake and maintenance of net charge within the binuclear center domain.

39 or input pathway for protons which go to the binuclear center for water formation ("chemical protons"

40 In contrast, reduction of the binuclear center in the "as-isolated" ferric/cupric enzy

41 ibonucleotide reductase to match that of the binuclear center in the hydroxylase component of methane

42 ox-linked export of a pumped proton from the binuclear center into the exit pathway.

43 ince both modifications are prevented if the binuclear center is first blocked with cyanide.

44 rosine hydroxyl group is protonated when the binuclear center is oxidized but deprotonated in the P(M

45 f the dominant EPR spectrum from the coupled binuclear center of Mn/Mn-PTE requires slightly rhombic

46 rogen peroxide does more than react with the binuclear center of oxidized bovine cytochrome c oxidase

47 tryptophan and cardiolipin proceeds via the binuclear center since both modifications are prevented

48 the proton may instead be transferred to the binuclear center to complete the oxygen reduction chemis

49 migration of a free radical generated at the binuclear center to these distal reaction sites.

50 e redox states with only one electron in the binuclear center with respect to those with either zero

51 g while continuing to channel protons to the binuclear center without inhibiting the oxidase activity

52 s initial binding of H2 to the copper of the binuclear center, displacing the bound water, followed b

53 into the binding pocket of the loosely bound binuclear center, originally occupied by the nucleophili

54 One proton goes to the binuclear center, whereas the other is pumped to the low

55 a copper-hydride intermediate to reduce the binuclear center.

56 al change takes place in the vicinity of the binuclear center.

57 ggest regulation of the oxygen supply to the binuclear center.

58 and leads to another acidic residue near the binuclear center.

59 m E286 to the heme a(3) D-propionate and the binuclear center.

60 f CcO are unrelated to ligand binding to the binuclear center.

61 6 residue physically impede NO access to the binuclear center.

62 A likely role of a binuclear chelate effect is implicated for the unique S-

63 reaction likely proceeds via an unsymmetric binuclear chromium bis(mu-oxo) complex.

64 novel protein with the Gal4-type Zn(II)2Cys6 binuclear cluster DNA-binding motif at the N terminus.

65 Hap1 belongs to the Zn(2)Cys(6) zinc binuclear cluster family of transcription factors that t

66 The binuclear cluster N1a and the tetranuclear cluster N7 ar

67 The zinc binuclear cluster transcription factor CLR-1 is necessar

68 llection identified two uncharacterized zinc binuclear cluster transcription factors (clr-1 and clr-2

69 ctors, including the fungal Zn(II)2Cys6 zinc binuclear cluster transcription factors, the DNA binding

70 g that the two Mn(II) ions are not forming a binuclear cluster.

71 inal coiled-coil and a carboxy-terminal zinc binuclear cluster.

72 The binuclear Co-complexes are coordinated to mu-bonded, fiv

73 It has been established that this binuclear cofactor is synthesized and assembled by three

74 yzed by Pd(2)(dba)(3) and CyPF-(t)Bu was the binuclear complex [Pd(CyPF-(t)Bu)](2)(mu(2),eta(2)-dba)

75 A butterfly-like phosphorescent platinum(II) binuclear complex can undergo a molecular structure chan

76 for the functioning of both Co2+ ions of the binuclear complex found in the X-ray structure of E. col

77 ononuclear complexes in equilibrium but as a binuclear complex in its single crystals.

78 y published MntR.Mn(2+) structure revealed a binuclear complex of manganese ions with a metal-metal s

79 Cu(II/I) by formation of a hydroxide-bridged binuclear complex, Mn(II)(mu-OH)Mn(II), at the substrate

80 trongly activating because they can form the binuclear complex, while smaller metal ions cannot bind

81 (pop-BF2)(6-) a very rare 6p(2) sigma-bonded binuclear complex.

82 tivity difference between the trinuclear and binuclear complexes at parity of histamine ligand is str

83 The synthesis of a series of binuclear complexes comprising bis(2,2':6',2' '-terpyrid

84 monodentate surface complexes to bidentate, binuclear complexes had Gibbs free energies of activatio

85 m and calcium complexes of MntR also contain binuclear complexes with a 4.4 A internuclear separation

86 Previous work has shown that MntR forms binuclear complexes with Mn(2+) or Cd(2+) at two binding

87 Novel binuclear complexes, 4,4'-bis{[N-(2,6-diisopropylphenyl)

88 the zero-field splitting parameter D in two binuclear complexes, [Cu(CF(3)COO)(2) x CH(3)CN](2) and

89 escent molecular rotor, only observed in the binuclear compound, was decreased with increasing viscos

90 lent mu-eta(2):eta(2) peroxy bridged coupled binuclear copper active sites.

91 xidation of phenols to catechols through the binuclear copper centres.

92 rsion of carbon dioxide into oxalate using a binuclear copper complex and a mild reducing agent.

93 ted that this enzyme belonged to the coupled binuclear copper enzyme (CBC) family.

94 The binuclear copper enzyme tyrosinase activates O2 to form

95 In tyrosinase, a binuclear copper enzyme, a mu-eta(2):eta(2)-peroxodicopp

96 of aromatic substrates catalyzed by coupled binuclear copper enzymes has been observed with side-on-

97 Tyrosinases are ubiquitous binuclear copper enzymes that oxygenate to Cu(II) 2 O2 c

98 rises from TCNQ guest molecules bridging the binuclear copper paddlewheels in the framework, leading

99 sites in the oxidized form of the noncoupled binuclear copper protein peptidylglycine alpha-hydroxyla

100 erimentally derived mechanism of the coupled binuclear copper protein tyrosinase.

101 ional and spectroscopic model of the coupled binuclear copper protein tyrosinase.

102 Recent studies support a binuclear copper site as the catalytic center.

103 A homologous series of binuclear copper(II) complexes [Cu(II)(2)(Nn)(Y)(2)](2+)

104 opy (EXAFS), the formation of both bidentate binuclear corner-sharing ((2)C) and bidentate mononuclea

105 rdination at a distance of 3.43 A suggests a binuclear corner-sharing adsorption/incorporation U(IV)

106 suggested predominant formation of bidentate binuclear corner-sharing complexes ((2)C) for As(V), and

107 This anion was attracted via bidentate binuclear corner-sharing coordination between SeO3(2-) t

108 ixture of As(III) and As(V), forms primarily binuclear, corner-sharing As(V) surface complexes on EC

109 nds 4 mol equiv of Cu (I) to form an alpha3N binuclear Cu (I) 2S 4 cluster by X-ray absorption spectr

110 monooxygenase (PHM), which has a noncoupled binuclear Cu active site.

111 ase active sites, as compared to the coupled binuclear Cu active sites in hemocyanin, tyrosinase, and

112 These proteins have binuclear Cu active sites that are distant, that exhibit

113 d exchange coupling interactions between the binuclear Cu centers.

114 O(2) intermediates in the coupled binuclear Cu enzymes can be trapped and studied spectros

115 Possible intermediates in noncoupled binuclear Cu proteins can be defined through correlation

116 ferent intermediates in these two classes of binuclear Cu proteins exhibit different reactivities tha

117 Coupled binuclear Cu proteins include hemocyanin, tyrosinase, an

118 Noncoupled binuclear Cu proteins include peptidylglycine alpha-hydr

119 Binuclear Cu proteins play vital roles in O(2) binding a

120 Cu(I) and TEMPO-H are oxidized by O(2) via a binuclear Cu(2)O(2) intermediate and (2) "substrate oxid

121 ntain antiferromagnetically exchange-coupled binuclear Cu(2+) sites in which two Cu(2+) ions are brid

122 This binuclear Cu(I) site reacts with N2O to generate the exp

123 ](2+) active sites from the reaction between binuclear Cu(I) sites and N2O in the 10-membered rings C

124 rdinate was evaluated for two representative binuclear Cu(I) sites.

125 n contrast to the nucleophilic reactivity of binuclear Cu(II) end-on peroxo species.

126 structures confirm the complexes to contain binuclear Cu(II) paddlewheel nodes each bridged by four

127 ite contains a [4Fe-4S] cluster bridged to a binuclear Cu-Ni site.

128 consists of a [4Fe-4S] cluster bridged to a binuclear CuNi center with Cu at the proximal metal site

129 oroform gives a mixture of two regioisomeric binuclear diaminocarbene complexes.

130 or Si, on the other hand, are found to form binuclear dihydride complexes of the type Me(2)E(R(n)C(5

131 of classical ligand-bridged intermediates in binuclear eliminations) in halogen elimination reactions

132 CcrA is the prototypical binuclear enzyme belonging to the B1 MbetaL family, whic

133 a trinuclear Fe binding center comprising a binuclear Fe binding center (sites A and B), homologous

134 terized high-valent mono- and di-oxo bridged binuclear Fe model complexes.

135 -peroxo 3 are compared with those of related binuclear Fe- and Cu-peroxo compounds.

136 ith aryldiazoacetates was achieved using the binuclear gold catalyst (S)-xylylBINAP(AuCl)(2), activat

137 zoacetates with enol ethers catalyzed by the binuclear gold complex (R)-DTBMSegphos(AuCl)2 activated

138 The reaction employs a binuclear gold(I) bromide as a catalyst and Selectfluor

139 In part, this reaction is mediated by the binuclear heme a3/CuB active site of cytochrome c oxidas

140 mitochondrial respiration by binding to the binuclear heme a3/CuB center in cytochrome c oxidase.

141 n of the ferric/cupric state of the enzyme's binuclear heme a3/CuB center is coupled to proton pumpin

142 spin heme b(558) that donates electrons to a binuclear heme b(595)/heme d center.

143 ide on the redox properties of an engineered binuclear heme-copper center in myoglobin (Cu(B)Mb) were

144 5)H(3)N, reacts with excess H(2) to give the binuclear hydride species, {[N(3)]Ru(H)}(2)(mu-eta(1):et

145 d EXAFS results indicated that the bidentate binuclear inner sphere was the most probable type of lig

146 iple layer SCM by implementing the bidentate-binuclear inner-sphere complexation identified in the pr

147 ms both outer-sphere complexes and bidentate-binuclear inner-sphere complexes on ferrihydrite surface

148 e NMR results suggest formation of bidentate binuclear inner-sphere surface complexes was the dominan

149 Reductive elimination via ligand-bridged binuclear intermediates from bimetallic cores is one mec

150 Oxygenation occurs at the binuclear iron active centre in the hydroxylase componen

151 oli ribonucleotide reductase (R2) contains a binuclear iron cluster with inequivalent binding sites:

152 ld be a structural mechanism used by natural binuclear iron enzymes to drive their reactions past per

153 the four conserved His-Glu motifs suggest a binuclear iron mediated reaction mechanism, distinct fro

154 in which monomers A and B exhibit mono- and binuclear iron occupancy, respectively.

155 e to glutamate substitution (R2-D84E) at the binuclear iron site modifies the endogenous ligand set o

156 e of [FeFe] hydrogenase contains a catalytic binuclear iron subsite coordinated by CN(-) and CO ligan

157 n proposed that the electron transfer to the binuclear iron-copper center of O2 reduction initiates t

158 c cubane [4Fe-4S]-cluster (4FeH) linked to a binuclear iron-sulfur cluster (2FeH) that has an open co

159 Hydrolysis of a Pacman-shaped binuclear magnesium complex of a polypyrrolic Schiff bas

160 complex yields an unprecedented view of the binuclear manganese cluster and illuminates the structur

161 The structure and stability of the binuclear manganese cluster are critical for catalytic a

162 bridging coordination interactions with the binuclear manganese cluster in the arginase active site.

163 ide ion of the native enzyme and bridges the binuclear manganese cluster with an ionized NH(-) group.

164 The binuclear manganese metalloenzyme human arginase I (HAI)

165 Arginase is a binuclear manganese metalloenzyme that catalyzes the hyd

166 Arginase is a binuclear manganese metalloenzyme that catalyzes the hyd

167 Arginase is a binuclear manganese metalloenzyme that serves as a thera

168 ral comparisons of arginase with the related binuclear manganese metalloenzymes agmatinase and procla

169 A binuclear manganese molecular complex [(OH2)(terpy)Mn(mu

170 to propose a chemical mechanism for mono and binuclear MbetaLs.

171 ing NMR, EPR, and mass analyses, indicates a binuclear mechanism involving an O-atom transfer by a pe

172 at the binding of substrate analogues to the binuclear metal center diminishes the population of hydr

173 ly of hydrolytic enzymes is a mononuclear or binuclear metal center embedded within the confines of a

174 ile is mirrored by structural motions of the binuclear metal center in the active site.

175 +) or Mn(2+) produced a protein containing a binuclear metal center in the putative active site forme

176 Ligands to the binuclear metal center include His 68, His 70, His 201,

177 n folds as a (beta/alpha)7beta-barrel, and a binuclear metal center is found at the C-terminal end of

178 X-ray diffraction studies have shown that a binuclear metal center is positioned in the active site

179 onstrated that the active site consists of a binuclear metal center positioned at the C-terminal end

180 The active site is composed of a binuclear metal center similar to that found in phosphot

181 structure the phosphonate moiety bridges the binuclear metal center, and one oxygen atom interacts wi

182 that bridges the two divalent cations of the binuclear metal center.

183 rotonation of the hydroxide that bridges the binuclear metal center.

184 d through complexation with a mononuclear or binuclear metal center.

185 ia complexation to the beta-metal ion of the binuclear metal center.

186 ion that occupied the alpha site within the binuclear metal center.

187 In the binuclear metal centers, the carbonyl and phosphoryl gro

188 ld, with four acidic residues coordinating a binuclear metal cluster within the active site, whose to

189 A binuclear metal coordination complex of the first thiazy

190 Various binuclear metal ion clusters and complexes have been rec

191 The protein consists of a core binuclear metallo-phosphoesterase fold (exemplified by b

192 sterase (PTE) from Pseudomonas diminuta is a binuclear metalloenzyme that catalyzes the hydrolysis of

193 Phosphotriesterase (PTE) is a binuclear metalloenzyme that catalyzes the hydrolysis of

194 Simulating such binuclear metalloenzymes accurately but computationally

195 in the design of inhibitors targeting other binuclear metalloenzymes.

196 a for other phosphodiesterase members of the binuclear metallophosphoesterase family and draw inferen

197 Binuclear metallophosphoesterases are an enzyme superfam

198 stal structure and bound by coordinating the binuclear metals and forming hydrogen bonds and nonpolar

199 synthesized and characterized a panel of new binuclear mixed valence Cu(I,II) complexes containing su

200 1 sites is well defined, yet its role in the binuclear mixed-valent CuA sites is less clear.

201 reactive RNA ends are in the vicinity of the binuclear Mn(2+) active center, which provides detailed

202 cture and harboring the active site with the binuclear Mn(2+) ions.

203 i) mechanism for its transformation into the binuclear Mn(II) complex with ((H)O)L-L(OH) and its hydr

204 d the synthesis of a functionally equivalent binuclear Mn(II) species.

205 resents the first characterized example of a binuclear Mn(III)-peroxo, and a rare case in which more

206 on [Mn(II)] concentration, consistent with a binuclear Mn(O2(2-)) Mn peroxo.

207 Vibrational and metrical parameters for binuclear Mn-peroxo 3 are compared with those of related

208 ediate state trapped during reduction of the binuclear Mo/Cu enzyme CO dehydrogenase by CO.

209 active site of the native enzyme is a unique binuclear molybdenum- and copper-containing center.

210 zation of intermediates formed en route to a binuclear mono-oxo-bridged Mn(III) product {[Mn(III)(S(M

211 The synthesis of discrete, cationic binuclear mu-aryl dicopper complexes [Cu2(mu-eta(1):eta(

212 n one intermediate is observed en route to a binuclear mu-oxo-bridged product derived from O2.

213 The reactivity of these binuclear Ni complexes highlights the fundamental differ

214 The binuclear Ni(III) -Ni(III) intermediate lacks a Ni-Ni bo

215 ubunit of the ACDS complex and composed of a binuclear Ni-Ni site bridged by a cysteine thiolate to a

216 mposed of an [Fe(4)S(4)] center bridged to a binuclear Ni-Ni site.

217 A series of binuclear NiNi complexes supported by a single thiolate

218 This binuclear [(NO)Fe(N2S2)Fe(NO)2](+) complex maintains str

219 otein fold and primary ligand set of various binuclear non-heme iron enzymes.

220 ctivating step of the catalytic cycle of the binuclear nonheme iron enzyme Delta(9) desaturase.

221 High-valent intermediates of binuclear nonheme iron enzymes are structurally unknown

222 on the high-valent oxo intermediates in the binuclear nonheme iron enzymes.

223 Binuclear organometallic molecules are model systems for

224 Shown herein is that mono- and binuclear organoscandium complexes with a borate cocatal

225 ribution describes the implementation of the binuclear organotitanium "constrained geometry catalysts

226 ed by radicals and proceeds by an unexpected binuclear outer-sphere mechanism to cleanly form trans-i

227 bio-inspired electrochemical sensor using a binuclear oxo-manganese complex was evaluated and applie

228 ion the reducing equivalent is stored on the binuclear part, ([4Fe-4S](2+)Fe(II)Fe(I) --> [4Fe-4S](2+

229 escence intensity of the nano optical sensor binuclear Pd(atz,ur) complex at 457nm by the 2-chloro-4-

230 computational studies of the oxidation of a binuclear Pd(II) complex with "CF(3)(+)" reagents.

231 In contrast, oxidation of binuclear Pd(II) complexes with electrophilic trifluorom

232 Oxidation of binuclear Pd(II) complexes with PhICl(2) or PhI(OAc)(2)

233 nt, and formally electron-deficient (32e(-)) binuclear Pd(II)-C(0) complexes of 2-methyl-1H-indene we

234 The observation that binuclear Pd(III) and mononuclear Pd(IV) complexes are a

235 (OAc)(2) has previously been shown to afford binuclear Pd(III) complexes featuring a Pd-Pd bond.

236 agmentation of an initially formed, formally binuclear Pd(III), intermediate.

237 A new nano optical sensor binuclear Pd-(2-aminothiazole) (urea), Pd(atz,ur) comple

238 The new binuclear phenoxyiminato zirconium complex {1,7-(O)2C10H

239 nally designed butterfly-like phosphorescent binuclear platinum complexes that undergo controlled PSC

240 rivatives with regard to tetranuclear versus binuclear product formation is proposed to be connected

241 The binuclear Pt (pca)(bpy) has +II net charge which is very

242 escence intensity of the nano optical sensor binuclear Pt(pca) (bpy) at 528nm after excitation at 370

243 the luminescence intensity at 528nm of nano binuclear Pt(pca) (bpy) doped in sol-gel matrix by vario

244 tween 3-nitrotyrosine and the optical sensor binuclear Pt-2-pyrazinecarboxylic acid (pca)-Bipyridine

245 clear (RAs-Fe = 2.88-2.94 A) and monodentate binuclear (RAs-Fe = 3.35-3.41 A) complexes with Fe, thus

246 DFT modeling of the binuclear reaction pathway of the O-O bond formation in

247 me c oxidase from the cellular inside to the binuclear redox center (BNC) can occur through two disti

248 me c oxidase from the cellular inside to the binuclear redox center (BNC) can occur through two disti

249 ion of halide-bridged structures establishes binuclear reductive elimination as a viable mechanism fo

250 involve all monomeric Rh intermediates and a binuclear Rh intermediate in the other case, are propose

251 it quantitative comparisons with related 2D, binuclear Ru(II) ammine complex salts.

252 investigated DNA threading intercalation by binuclear ruthenium complex [mu-dppzip(phen)4Ru2](4+) (P

253 dent threading intercalation kinetics of the binuclear ruthenium complex Delta,Delta-[mu-bidppz-(phen

254 The dumbbell shaped binuclear ruthenium complex DeltaDelta-P requires transi

255 me, was investigated using a new photoactive binuclear ruthenium complex, [Ru(bipyrazine)2]2(quaterpy

256 Here, we characterize a family of binuclear ruthenium compounds that selectively target th

257 cal form of the cross-linked tyrosine in the binuclear site may be more significant in the catalytic

258 onstraints on the geometry and energy of the binuclear site of both R2-wt and variant R2s are also ex

259 of binding of formate to the heme a(3-)Cu(B) binuclear site of bovine cytochrome c oxidase has been o

260 iating the transfer of copper into the Cu(A) binuclear site.

261 nodentate end-on-bound O2 to one iron in the binuclear site.

262 to state O is initiated by hydration of the binuclear site.

263 tate, suggesting that the cobalt ions in the binuclear sites are not magnetically coupled.

264 an be classified into coupled and noncoupled binuclear sites based on the magnetic interaction betwee

265 on is very low, there is a small fraction of binuclear sites in EcMetAP formed through cooperative bi

266 In other cases a binuclear species can persist through the catalytic cycl

267 In contrast, monodentate binuclear species of (-O)2-COHx=[0,1], are expected to f

268 ate the dynamical flexibility of the bridged binuclear structural motif in the active site of arginas

269 The binuclear subsite Fe2(adt)(CO)3(CN)2 is attached through

270 ydrogenase with a selectively (57)Fe-labeled binuclear subsite is described.

271 ved in addition to the majority of bidentate binuclear surface complexes on a wet paste sample prepar

272 lanolytic chain-transfer processes, with the binuclear system exhibiting a sublinear relationship bet

273 orporation of electroactive units into these binuclear systems has been pursued, affording multicompo

274 nct metal sites (T1 in domain 3, T2, and the binuclear T3 at the interface between domains 1 and 3).

275 in the RO form of a high-potential MCO, the binuclear T3 Cu(II) site can be reduced via the 700 mV T

276 Alternatively, when this fully reduced binuclear T3 site is oxidized via the T1 Cu, a different

277 four Cu atoms, including T1, T2, and coupled binuclear T3 sites.

278 ononuclear eta(1)-superoxo species, and then binuclear trans-mu-1,2-peroxo-bridged complexes.

279 luding gliZ, encoding a putative Zn(2)Cys(6) binuclear transcription factor.

280 tic applications, allow us to propose that a binuclear transmetalation intermediate is the reactive s

281 r Cu cluster composed of a type 2 (T2) and a binuclear type 3 (T3) site that together catalyze the fo

282 unction with a mononuclear Type 2 (T2) and a binuclear Type 3 (T3) site, arranged in a trinuclear cop

283 xidized), because the type 2 and the coupled-binuclear type 3 Cu centers in the O(2)-reducing trinucl

284 type 1 (T1), one type 2 (T2), and a coupled binuclear type 3 Cu pair (T3).

285 ions: one type 1, one type 2, and a coupled binuclear type 3 site.

286 is reaction: the type 1, type 2, and coupled binuclear type 3 sites.

287 The coupled binuclear "type 3" Cu sites are found in hemocyanin (Hc)

288 Cu atoms: a type 1, a type 2, and a coupled binuclear, type 3 site.

289 ure, reactivity and magnetic properties of a binuclear uranium-oxo complex.

290 gene possesses sequence motifs found in the binuclear zinc (Cys 6-Zn 2) family of transcription fact

291 ing control by a transcription factor of the binuclear zinc cluster family.

292 (fluffy) gene of Neurospora crassa encodes a binuclear zinc cluster protein that regulates the produc

293 vel coordination sites, including an unusual binuclear zinc cluster.

294 ptor, the protease domain of PSMA contains a binuclear zinc site, catalytic residues, and a proposed

295 We show that this enzyme possesses a binuclear zinc-active site in which one of the zinc ions

296 A recognition motif domains and a C-terminal binuclear zinc-binding domain are required for mRNA bind

297 s are renowned for nucleic acid recognition, binuclear zinc-binding structural motifs, such as LIM (L

298 osphodiesterase (NPP), have nearly identical binuclear Zn(2+) catalytic centers but show tremendous d

299 Overall, the results suggest that the binuclear Zn(2+) catalytic site remains very similar bet

300 olynuclear unit consisting of an oxo-bridged binuclear ZrOCo(II) group coupled to an iridium oxide na