ライフサイエンスコーパス: bioactive peptide

1 fied and should be considered as a potential bioactive peptide.

2 nd strategies followed for the generation of bioactive peptides.

3 tease that inactivates enkephalins and other bioactive peptides.

4 nd adipose tissues), generates at least four bioactive peptides.

5 ics approach for the discovery of endogenous bioactive peptides.

6 overy and structure-function studies of many bioactive peptides.

7 me, to transform recombinant precursors into bioactive peptides.

8 dent metallopeptidases that metabolize small bioactive peptides.

9 can serve as a bioorthogonal modification of bioactive peptides.

10 ing of a number of physiologically important bioactive peptides.

11 incorporated into the structure of selected bioactive peptides.

12 tensin I, des-Arg bradykinin, and many other bioactive peptides.

13 me that converts prohormone intermediates to bioactive peptides.

14 dogenous pro-opiomelanocortin to the correct bioactive peptides.

15 me, catalyzes the COOH-terminal amidation of bioactive peptides.

16 surface enzyme that hydrolyzes BLP and other bioactive peptides.

17 formation on sites with highest abundance of bioactive peptides.

18 onnective tissue protein extracts to produce bioactive peptides.

19 sites that, when cleaved, releases multiple bioactive peptides.

20 ve oil production based on the extraction of bioactive peptides.

21 hydrolysis to identify previously unreported bioactive peptides.

22 grade caseins at low temperature and produce bioactive peptides.

23 affect protein digestibility and release of bioactive peptides.

24 glass slides were selectively patterned with bioactive peptides.

25 ss spectrometry and to look for and quantify bioactive peptides.

26 at STP hydrolysates are potential sources of bioactive peptides.

27 Cyclotides are useful scaffolds to stabilize bioactive peptides.

28 successfully applied in the synthesis of two bioactive peptides: 2-aminoadamantane-2-carboxylic acid

29 Moreover, bioactive peptide 25 (Ki = 9 nM) achieved oral bioavaila

30 e P and thymosin-beta4, the precursor to the bioactive peptide Ac-SDKP.

31 n in a mouse model of acute colitis than the bioactive peptide alone, and showed enhanced stability i

32 The microchip was used for separation of bioactive peptides and amino acids labeled with a fluoro

33 tease, inactivates or degrades some of these bioactive peptides and chemokines, thereby regulating ce

34 These probiotics enhanced the generation of bioactive peptides and could possibly be commercially ap

35 etallopeptidase that metabolizes a number of bioactive peptides and degrades peptides released by the

36 e P (SP) belongs to the tachykinin family of bioactive peptides and exerts its many biological effect

37 Meprin substrates include bioactive peptides and extracellular matrix proteins.

38 ize a wide range of inorganic materials with bioactive peptides and have the potential to be used in

39 ny additional peptides, including additional bioactive peptides and proline rich peptides (PRPs).

40 The work herein was carried out to identify bioactive peptides and proteins that are susceptible to

41 the specific health benefits associated with bioactive peptides and the reduction of protein allergen

42 the specific health benefits associated with bioactive peptides and the reduction of protein allergen

43 ical opioid prohormones can generate several bioactive peptides, and these divergent families of proh

44 om a physiological point of view is that the bioactive peptides, angiotensins I and II and vasoactive

45 ein content with good amino acid balance and bioactive peptides (antioxidant, antihypertensive, immun

46 d 3) prevention of the inactivation of other bioactive peptides apart from GLP-1, such as glucose-dep

47 alpha-MSH and other bioactive peptides are cleavage products of pro-opiomela

48 ia californica as the model, a wide range of bioactive peptides are detected within each vesicle.

49 Several bioactive peptides are encrypted within the sequence of

50 The cleaved bioactive peptides are known to possess activities that

51 Bioactive peptides are oligopeptides that consist of 2-2

52 Bioactive peptides are packaged in large dense-core secr

53 es in these mice showed a decrease in mature bioactive peptides as a result of a decrease in both car

54 133 on the production of soybean flours with bioactive peptides as modulators of oxidative stress and

55 ulate physico- and biochemical properties of bioactive peptides as well as chiral inducers in asymmet

56 Numerous low molecular mass bioactive peptides (BAPs) can be generated during the hy

57 We designed a series of bioactive peptides based on deep analysis of VEGFR2-bind

58 trate, it will have multifactorial uses as a bioactive peptide by itself or in tissue engineering.

59 peptidase that yields endothelin-3, a potent bioactive peptide, by cleavage of big endothelin-3, a la

60 d in the biosynthesis of the broad family of bioactive peptides called ribosomally synthesized and po

61 ty to rapidly filter sequences for potential bioactive peptides can greatly compress the time between

62 Nonribosomally and ribosomally synthesized bioactive peptides constitute a source of molecules of g

63 In the current context of food safety, bioactive peptides could be of interest as preservatives

64 e present study was to determine whether the bioactive peptides could have been amelogenin protein de

65 searched the literature for all instances of bioactive peptides derived from milk proteins from any m

66 ate independently the secretion of different bioactive peptides derived from the same gene product.

67 is study provides support for the concept of bioactive peptide design based on protein surface epitop

68 e development of the PepSAVI-MS pipeline for bioactive peptide discovery.

69 is showed the production of multi-functional bioactive peptides due to the hydrolysis of whey protein

70 well as the loss in functional properties of bioactive peptides during storage.

71 to the detection of greater numbers of known bioactive peptides (e.g., peptide hormones) during the a

72 ZmPep1 is a bioactive peptide encoded by a previously uncharacterize

73 Bioactive peptide extracted at a hydrolysis condition of

74 carrier designed to prolong the presence of bioactive peptides following intraarticular delivery.

75 otential dual imaging probes consisting of a bioactive peptide for tumor targeting, a biocompatible d

76 kaline solution can be a potential source of bioactive peptides for addition to foods.

77 f random peptide libraries has yielded novel bioactive peptides for cell surface receptors.

78 It should be possible to identify novel bioactive peptides for orphan GPCRs by the combination o

79 ent observation of the very high affinity of bioactive peptides for oxidized fatty acids and phosphol

80 sts with other tumor systems, where multiple bioactive peptide fractions have been detected.

81 source of high quality proteins with various bioactive peptide fractions.

82 Bioactive peptides frequently terminate with an essentia

83 assembly of the C-36 peptide, a circulating bioactive peptide from the alpha1-antitrypsin serine pro

84 novel cyclic peptide that comprises a small bioactive peptide from the annexin A1 protein grafted in

85 rough the successful identification of known bioactive peptides from a botanical species, Viola odora

86 nsive, energy-efficient production of potent bioactive peptides from caseins in milk at low temperatu

87 oteases responsible for the release of these bioactive peptides from CgA have not been established.

88 hnology for the cost-effective production of bioactive peptides from lentil proteins during enzymatic

89 is by different proteases and the release of bioactive peptides from lentil proteins.

90 were considered for efficient production of bioactive peptides from RBP.

91 ection that can lead to efficient release of bioactive peptides from rice bran proteins for functiona

92 significantly inhibited in roots expressing bioactive peptides fused to the maize cytokinin oxidase/

93 fibroblast cell migration behavior across a bioactive peptide gradient illustrates preservation of p

94 xible technique for the covalent addition of bioactive peptide gradients to a surface or gel and a si

95 es validated the sequences of the synthetic, bioactive peptides HA and BMP2, which contained highly b

96 0 toxins from an estimated number of >70,000 bioactive peptides have been identified in the genus Con

97 gy in solid-phase peptide synthesis, several bioactive peptides have been prepared including cyclic,

98 Bioactive peptides have evolved to optimally fulfill spe

99 Bioactive peptides have multiple conformations in soluti

100 ble for the processing of CgA and release of bioactive peptides have not been established.

101 suggesting that it could yield more than one bioactive peptide; however, no in vivo activity has been

102 ccurrence of direct interaction between milk bioactive peptides, Ile-Asn-Tyr-Trp, Leu-Asp-Gln-Trp, an

103 so may contribute to an understanding of the bioactive peptides important in chondrocyte signaling.

104 es, and mammals illustrate the importance of bioactive peptides in controlling numerous complex behav

105 This is the first report of tyrosine-rich bioactive peptides in Conus venom.

106 rent works have demonstrated the presence of bioactive peptides in different soybean-based foodstuffs

107 pplied for expression and secretion of small bioactive peptides in mammalian cells.

108 nsible for processing the precursors of many bioactive peptides in mammals.

109 Clear evidence is shown of the presence of bioactive peptides in the jejunum of healthy humans who

110 egies to generate competitive antagonists of bioactive peptides include several possible structural m

111 POMC) is a precursor polypeptide for various bioactive peptides, including adrenocorticotropic hormon

112 successfully applied to a growing number of bioactive peptides, including alpha-, mu-, and omega-con

113 ase activity and degraded a variety of small bioactive peptides, including bradykinin, neurotensin, a

114 nc metallopeptidase that metabolizes several bioactive peptides, including insulin and the amyloid be

115 Insulin-degrading enzyme (IDE) hydrolyzes bioactive peptides, including insulin, amylin, and the a

116 a cell surface endopeptidase that hydrolyses bioactive peptides, including the bombesin-like peptides

117 PK2 is a bioactive peptide initially discovered as a regulator of

118 These cells are likely to secrete the bioactive peptides into the intestinal lumen in response

119 addition of the coupling agent gradient, the bioactive peptide is added.

120 An in vitro system for the preparation of bioactive peptides is described.

121 tion to the classical cleavages, a subset of bioactive peptides is generated by processing at "noncla

122 In contrast, a subset of bioactive peptides is generated by processing at non-cla

123 Search for bioactive peptides is intensifying because of the risks

124 However, the clinical usefulness of such bioactive peptides is limited because they are rapidly d

125 protein essential to the production of many bioactive peptides, is cleaved and enters the regulated

126 port on the anti-cancer potential of a novel bioactive peptide isolated from Momordica charantia in v

127 A large number of bioactive peptides isolated from natural sources are kno

128 on, M13 phages with genetically incorporated bioactive peptide ligands direct both soft and hard tiss

129 ith particular attention paid to identifying bioactive peptide ligands generated by post-translationa

130 Bioactive peptide LL-37/hCAP18, the only human member of

131 s used to measure the specific uptake of the bioactive peptide melittin into N-isopropylacrylamide (N

132 344SQ encapsulated in bioactive peptide-modified, matrix metalloproteinase-deg

133 Among the milk-derived bioactive peptides, only minor amounts of mono-phosphory

134 , confers resistance to polymyxin B and to a bioactive peptide (P2) derived from the human bactericid

135 for G protein-coupled receptors sensitive to bioactive peptides (peptide GPCRs).

136 Because these bioactive peptides play a role in the inflammatory respo

137 enzymes to convert inactive precursors into bioactive peptides plus several cytosolic proteins to go

138 ented shrimp pastes are potential sources of bioactive peptides possessing ACE inhibitory and antioxi

139 s encoding potential ligands and describe 22 bioactive peptide precursors.

140 composition, interactions, and properties of bioactive peptides present in different food matrices.

141 toglobulin or caseins, intensely studied for bioactive peptide production, relatively little attentio

142 that amyloids undergo transformation to the bioactive peptide/protein forms under specific condition

143 D7 isoform was produced and processed into a bioactive peptide referred to as nonadecaneuropeptide (N

144 d as a useful behavior for understanding how bioactive peptides regulate CNS function.

145 To review this large dataset, the bioactive peptides reported in the literature were visua

146 The production and regulated secretion of bioactive peptides require a series of lumenal enzymes t

147 Many bioactive peptides require amidation of their carboxy te

148 to explore the limits of affinity, with the bioactive peptide RGD as a model ligand.

149 Bioactive peptides (RQRK and VIK) were generated.

150 Bioactive peptide separated by gel-filtration chromatogr

151 a concise yet extensive survey of key short bioactive peptide sequences for a range of applications

152 gastrointestinal tract and may contain novel bioactive peptide sequences.

153 ts depending on the protease used to release bioactive peptide sequences.

154 ide a useful tool for cellular dissection of bioactive peptide signaling in a variety of organisms an

155 o pursue a comprehensive genetic analysis of bioactive peptide signaling, we have scanned the recentl

156 normal human lung and which hydrolyzes small bioactive peptides, some of which act as growth factors

157 using 125I-labeled GLP-1 confirmed that all bioactive peptides specifically displaced tracer with hi

158 ecialization of this neuropeptidase to small bioactive peptide substrates without bulky secondary and

159 e (IDE) is involved in the clearance of many bioactive peptide substrates, including insulin and amyl

160 is a protease that cleaves insulin and other bioactive peptides such as amyloid-beta.

161 biquitously participate in the catabolism of bioactive peptides such as neurotensin and bradykinin.

162 ansglutaminase-catalyzed covalent binding of bioactive peptides targeted to mineralized collagenous d

163 mass spectrometry and statistics to identify bioactive peptide targets from complex biological sample

164 A bioactive peptide that combines glucagon with the thyroi

165 yl tail, a beta-sheet forming peptide, and a bioactive peptide that is displayed on the surface of th

166 ed as the source of beta-casomorphins (BCMs) bioactive peptides that are implicated with various phys

167 connective tissue protein extracts produces bioactive peptides that are non-cytotoxic, should be sta

168 (GLP-1) and several other naturally produced bioactive peptides that contain preferentially a proline

169 oadrenal system, are processed by plasmin to bioactive peptides that feed back to inhibit secretagogu

170 r (EGFR) mediates the actions of a family of bioactive peptides that include epidermal growth factor

171 serves as a prohormone that is cleaved into bioactive peptides that inhibit catecholamine release, p

172 a novel platform for display and delivery of bioactive peptides that links the biological properties

173 es specialize in the hydrolysis of the small bioactive peptides that play a variety of signaling role

174 tonin (sCT) is an example of one of the many bioactive peptides that require amidation of the carboxy

175 P12 belongs to a new class of bioactive peptides that they have named epiviosamines.

176 putative roles and targets to host factors (bioactive peptides) that control gene expression in the

177 catalyzes the carboxyl-terminal amidation of bioactive peptides through a two-step reaction involving

178 e importance of disulfide bridges in a small bioactive peptide to bring together frustrated structure

179 poly(ethylene glycol), or PEG, modified with bioactive peptides to study murine models of lung adenoc

180 The construction of bioactive peptides using beta-amino acid-containing sequ

181 The bioactive peptide was identified as a nonmutated nonamer

182 Antioxidative bioactive peptide was successfully identified from pearl

183 The bioactive peptides, well-known to be in atrial gland ves

184 Antioxidative and antihypertensive bioactive peptides were successfully derived from Parkia

185 These novel bioactive peptides were suggested to be beneficial to nu

186 tegies represent an approach for stabilizing bioactive peptides while keeping their full potencies an

187 Lunasin is a 5-kDa soybean bioactive peptide with demonstrated anti-cancer and anti

188 rocesses big ET-3, generating ET-3, a potent bioactive peptide with multiple biological roles.

189 In this technique, bioactive peptides with a terminal cysteine are bound vi

190 In conclusion, bioactive peptides with distinctive properties could pot

191 o our knowledge, this is the first time that bioactive peptides with glucose uptake activity have bee

192 a model system for studying interactions of bioactive peptides with membranes.

193 e anti-biofilm surfaces were developed using bioactive peptides with proved activity to antibiotic re

194 s currently being applied to other important bioactive peptides with short half-lives.

195 onic side chains can be employed to generate bioactive peptides with significant systemic stability.

196 extracellular deposits represents a site of bioactive peptides with the ability to provide inappropr

197 probe for investigating the interactions of bioactive peptides with their receptors.

198 t important precursor of peptides, including bioactive peptides with various activities.

199 Two potential bioactive peptides, Xen-dorphin-1A and -1B, that were ch