ライフサイエンスコーパス: bioanalytical

1 is study in general satisfy the more relaxed bioanalytical acceptance criteria for modern drug discov

2 at can be covalently modified for a range of bioanalytical and acoustophoretic sorting applications.

3 makes HMP very attractive as a component of bioanalytical and bioenergetic devices.

4 gen lasers are an attractive combination for bioanalytical and biomedical applications.

5 of new functional materials for a number of bioanalytical and biosensor technologies for medical dia

6 trodes represents a promising methodology in bioanalytical and chemical sensing.

7 indicates great promise for a wide range of bioanalytical and environmental applications.

8 o control biomolecular transport systems for bioanalytical and sensing applications, as well as for t

9 Also discussed are the potential bioanalytical and therapeutic applications of mismatch-b

10 on of DNA oligonucleotides onto surfaces for bioanalytical and top-down bio-inspired nanobiofabricati

11 The bioanalytical application of the method is demonstrated

12 inexpensive, portable, and accurate tool for bioanalytical applications in laboratory and clinical se

13 vidin for biotin has made it useful for many bioanalytical applications involving the immobilization

14 were used in this report to demonstrate the bioanalytical applications of ambient ion landing.

15 ntensity with CPL activity should enable new bioanalytical applications of macromolecules in chiral e

16 ely young field that explores biomedical and bioanalytical applications of organometallic complexes,

17 Two bioanalytical applications of this micropatterned surfac

18 Finally, we demonstrated potential bioanalytical applications of this SNA-based stochastic

19 that it is an advantageous configuration for bioanalytical applications such as therapeutic drug moni

20 An example is in bioanalytical applications where microsensing at live pr

21 Bioanalytical applications, however, require a subsequen

22 it an advantageous configuration for several bioanalytical applications, including doping in sports,

23 employing GFP or its mutants in a number of bioanalytical applications, such as clinical analysis an

24 propriate for pesticide residue analysis and bioanalytical applications, was demonstrated.

25 ioconjugated systems, biosensing and related bioanalytical applications.

26 d protein complexes commonly used in several bioanalytical applications.

27 agging of biomolecules for a wide variety of bioanalytical applications.

28 g (SERS) responses in immunoassays and other bioanalytical applications.

29 nanoliter volume solutions for microfluidic bioanalytical applications.

30 integrated fluorescence detection system for bioanalytical applications.

31 standards, probes, and templates in various bioanalytical applications.

32 le, and provides the requisite stability for bioanalytical applications.

33 us offers significant utility in a myriad of bioanalytical applications.

34 OC diagnostics, immunoassays and diversified bioanalytical applications.

35 , making it beneficial for environmental and bioanalytical applications.

36 ing IM-MS a powerful approach for a range of bioanalytical applications.

37 A bioanalytical approach was used to identify chemical con

38 hat adversely affects wildlife, we applied a bioanalytical approach.

39 re the ultimate limits of the performance of bioanalytical approaches based on the detection of indiv

40 he hard drive industry can be applied to the bioanalytical arena where submicrometer to 100 mum separ

41 t of protocols to move GMR concepts into the bioanalytical arena.

42 step in assuring the quality of an LC-MS/MS bioanalytical assay and the integrity of bioanalysis con

43 ough the method development of a uHPLC-MS/MS bioanalytical assay for the quantitation of ketoconazole

44 d sensitive affinity recognition elements in bioanalytical assay formats, thereby opening up the fiel

45 tography-tandem mass spectrometry (LC-MS/MS) bioanalytical assay of dapagliflozin in human plasma.

46 We describe a simple bioanalytical assay platform consisting of a large array

47 d internal standard (SIL-IS) for an LC-MS/MS bioanalytical assay.

48 reated a new method to amplify the signal of bioanalytical assays based on the autocatalytic activati

49 tools, immunogenicity assessments, and other bioanalytical assays can be used to better understand pr

50 ing whether this approach can lead to robust bioanalytical assays for proteins.

51 In conclusion, a series of bioanalytical assays should be performed to standardize

52 Versatile bioanalytical assays to detect chemically stabilized ham

53 5 assay could be used for the development of bioanalytical assays to provide preclinical and clinical

54 rapid method development of high-throughput bioanalytical assays using ultra high-performance liquid

55 opment, but necessitates extremely sensitive bioanalytical assays, typically in the pg/mL concentrati

56 undamental importance in many diagnostic and bioanalytical assays, yet current detection techniques t

57 sulting protein chips for the development of bioanalytical assays.

58 cured an important position for their use in bioanalytical assays.

59 l be a valuable tool for the design of novel bioanalytical assays.

60 e biomimetic tools for nanobiotechnology and bioanalytical assays.

61 t methods used in sample preparation for the bioanalytical assessment of disinfected drinking water r

62 Bioanalytical assessments of anti-drug antibodies (ADAs)

63 ys are hence compatible with a wide range of bioanalytical, biophysical, and cell biological studies

64 Besides protein complexity, the greatest bioanalytical challenge facing comprehensive analysis of

65 ce, the system was applied to a contemporary bioanalytical challenge, specifically the analysis of in

66 ptimization is to improve its analytical and bioanalytical characterization by assessing three main A

67 al tissue often presents a challenge for the bioanalytical chemist.

68 lation platform represents a new approach in bioanalytical chemistry based on active transport of pro

69 d practicality of nanobody-based reagents in bioanalytical chemistry is demonstrated.

70 sue engineering, cell implant protection and bioanalytical chemistry.

71 can find many applications in analytical and bioanalytical chemistry.

72 QDs have found their niche in the bioanalytical community due to their remarkable brightne

73 In response to the needs of the bioanalytical community, here we report the creation of

74 This strategy significantly improves bioanalytical data quality and saves time, costs, and re

75 gest promise for these devices in label-free bioanalytical detection systems.

76 g carboxylic functional films for label-free bioanalytical detection techniques.

77 -ray crystallography and revises the earlier bioanalytical determinations.

78 s substantial improvements as a substrate in bioanalytical devices and is likely to find widespread u

79 TRAP has application in lab-on-a-chip bioanalytical devices as well as in the fabrication of p

80 nces in the application of AuNPs as label in bioanalytical devices, especially electrochemical immuno

81 nd cooling in electronic, optoelectronic and bioanalytical devices, where cooling is currently achiev

82 d, sensitive, reproducible, and miniaturized bioanalytical devices, which exploit the high binding av

83 -8 properties limit its application in these bioanalytical devices.

84 f protein molecules in integrated, nanoscale bioanalytical devices.

85 rokinetic systems applicable to microfluidic bioanalytical devices.

86 ther lipid rich species and a wider range of bioanalytical end points.

87 antitative Western blotting is a long-sought bioanalytical goal in the life sciences.

88 s validated in accordance with international bioanalytical guidelines over the clinically relevant ra

89 A quantitative bioanalytical high-pressure liquid chromatography-tandem

90 A quantitative bioanalytical HPLC-MS/MS assay requiring small blood vol

91 Bioanalytical imaging techniques have been employed to i

92 sease have increased the demand for portable bioanalytical instrumentation and point-of-care.

93 s with least-squares regression algorithm in bioanalytical LC-MS/MS assays is reported.

94 ways be used as the weighting factor for all bioanalytical LC-MS/MS assays.

95 ration methods and established protocols for bioanalytical mass spectrometry, a high-throughput, smal

96 Quantitative bioanalytical measurements are commonly performed in a k

97 ctrometric determination in applications for bioanalytical measurements for these important compounds

98 e of these particles, making them useful for bioanalytical measurements, is also demonstrated.

99 ce architectures with potential relevance to bioanalytical, medical, or "BioMEMS" applications.

100 A bioanalytical method based on nanoflow liquid chromatogr

101 pectrometry (TOF-SIMS) is a well-established bioanalytical method for directly imaging the chemical d

102 hroughput selected reaction monitoring LC-MS bioanalytical method for the determination of idoxifene,

103 wing work describes a combined enzymatic and bioanalytical method that permits absolute quantitation

104 for idoxifene and tamoxifen satisfy current bioanalytical method validation criteria on two separate

105 osed method was fully validated according to bioanalytical method validation guidelines.

106 Therefore, a reliable bioanalytical method which can differentiate recovery lo

107 The complete bioanalytical method, based on the automated LLE and fas

108 generally adopted acceptance criteria for a bioanalytical method.

109 the feasibility and utility of the proposed bioanalytical method.

110 Bioanalytical methods based on automated solid-phase ext

111 ng technology that could replace many of the bioanalytical methods currently used in drug discovery,

112 ighly desirable, development of ADA-tolerant bioanalytical methods enabling unbiased measurement of b

113 rands is fundamental to nearly all molecular bioanalytical methods ranging from polymerase chain reac

114 nance spectroscopy (and, in principle, other bioanalytical methods that use derivatized SAMs on gold,

115 ctionalization, particles are widely used in bioanalytical methods to capture molecular targets.

116 nzyme conjugate is commonly employed in many bioanalytical methods to increase assay sensitivity.

117 the most critical issues associated with the bioanalytical methods used for dried blood spot (DBS) sa

118 dicines Agency in Guideline on Validation of Bioanalytical Methods was performed.

119 and elimination of the matrix effect in the bioanalytical methods, but the experimental procedures n

120 n data usually provided for the conventional bioanalytical methods, need to be conducted to confirm H

121 Using both radiolabeling and sensitive bioanalytical methods, we demonstrate that the formyl mo

122 genetic engineering techniques coupled with bioanalytical methods, we have employed site-directed mu

123 n each microchannel, achieved via optical or bioanalytical methods, yields quantitative data on the s

124 Single-cell bioanalytical microanalysis has also become increasingly

125 applied to capture and transport analytes in bioanalytical microdevices.

126 the detectability of single fluorophores for bioanalytical monitoring.

127 ensional electrophoresis is demonstrated for bioanalytical objectives where replicate experiments are

128 anoparticle tags thus show great promise for bioanalytical or product-tracking/identification/protect

129 a case study, we investigate and compare the bioanalytical performance of flow-through surface plasmo

130 routine clinical analysis and now provides a bioanalytical platform for the development of similar as

131 Here, we present a bioanalytical platform for the quantification of positio

132 the goal to develop a simple, rapid, and new bioanalytical platform of HLM useful for drug metabolism

133 materials offers new working perspectives as bioanalytical platforms.

134 of palladium(II) reagents in biochemical and bioanalytical practice.

135 on, such as the type of transducer platform, bioanalytical principles (affinity or kinetic), and bior

136 of their function are difficult for any one bioanalytical probe to measure.

137 roscopy, in a wide variety of analytical and bioanalytical problems.

138 t time and cost savings and greatly simplify bioanalytical procedures compared to current manual prac

139 This novel approach simplifies current bioanalytical procedures providing time and cost savings

140 rein originally introduce different reliable bioanalytical procedures using filter paper as well as n

141 Each water type had a characteristic bioanalytical profile with particular groups of toxicity

142 alf-life; therefore, (198)Au can be used for bioanalytical purposes.

143 High-throughput bioanalytical quantitation using pcSFC-MS/MS for pharmac

144 lly too low to be practical as diagnostic or bioanalytical reagents.

145 eriophage particles with aptamers for use as bioanalytical reporters, and demonstrate the use of thes

146 es based on gas-phase HDX more applicable in bioanalytical research.

147 practice is sometimes inadequate to confirm bioanalytical results that are unexpected.

148 evaluated, and proposed solutions to control bioanalytical risks from nonuniform matrix ion suppressi

149 od spots (DBS) as a widely used quantitative bioanalytical sampling technique for regulatory studies.

150 d present risk level-based 'fit-for-purpose' bioanalytical schemes for the investigations of treatmen

151 analyses and hence for wider applications in bioanalytical science.

152 Abundant opportunities exist for the bioanalytical sciences to help extend this revolutionary

153 Fc using biophysical (DSC, CD, and NMR) and bioanalytical (SEC and RP-HPLC-MS) methods.

154 anopores has found widespread application in bioanalytical sensing as a result of the inherent signal

155 ophysics and the production of surface-based bioanalytical sensor platforms.

156 also important embodiments of many types of bioanalytical sensors, pointing to an intriguing opportu

157 g a practical add-on unit in a wide range of bioanalytical setups, in particular as a first-dimension

158 Collectively, this study provides a bioanalytical strategy to validate the AR-interactome an

159 ated LLE techniques allowing high-throughput bioanalytical studies on small-volume samples using dire

160 standardized analytical approach to provide bioanalytical support for both preclinical and clinical

161 This assay can be widely used for bioanalytical support of future clinical studies for the

162 This new fluorogenic bioanalytical system is based on the GSH-mediated stabil

163 Given that the bioanalytical system is capable of processing promoter,

164 This bioanalytical system, furthermore, sophisticates in arra

165 el approach to extending the linear range of bioanalytical systems and biosensors by utilizing two en

166 reagent generation and to develop integrated bioanalytical systems for clinical diagnostics.

167 high-throughput organic synthesis products, bioanalytical target analysis for preclinical and clinic

168 linked glycans is among the most challenging bioanalytical tasks because of their complexity and vari

169 r these systems, which enable a range of new bioanalytical tasks with different samples and models in

170 ometry (MALDI-IMS) is an emerging label-free bioanalytical technique capturing the spatial distributi

171 l-free, spatially resolved, and multipurpose bioanalytical technique for direct analysis of biologica

172 salts on bacterial membrane was assessed by bioanalytical techniques including assays in model membr

173 ging versus those that could be utilized for bioanalytical techniques.

174 flow cytometry, and Western blot are common bioanalytical techniques.

175 s and opens new avenues for developing novel bioanalytical technologies for protein analysis.

176 tiple glycobiomarkers or as a rapid low-cost bioanalytical tool for glycoproteome analyses.

177 Effect-directed detection as bioanalytical tool for risk assessment showed coumarin t

178 that this approach could become an important bioanalytical tool to investigate the effect of treatmen

179 s (CE) has become increasingly valuable as a bioanalytical tool to quantify analytes from single cell

180 elucidation techniques is a straightforward bioanalytical tool, especially if microbiological assays

181 ens the door to greater utility of SIMS as a bioanalytical tool, such as lipid mapping of single cell

182 ple acoustic based mass sensor to a powerful bioanalytical tool.

183 ls when the micropallet arrays are used as a bioanalytical tool.

184 de surface has been shown to be an effective bioanalytical tool.

185 Consequently, bioanalytical tools can be applied complementary to chem

186 Conventional bioanalytical tools cannot efficiently examine ASV and P

187 n made in the development and application of bioanalytical tools for single cell metabolomics based o

188 crofluidic technologies are rapidly emerging bioanalytical tools that can miniaturize and revolutioni

189 this study demonstrates the applicability of bioanalytical tools to investigate DBP formation in a dr

190 recently developed RCA-based diagnostics and bioanalytical tools, and summarize the use of RCA to con

191 rea in Australia was assessed using in vitro bioanalytical tools, as well as through quantification o

192 ribed forms the basis for a diverse suite of bioanalytical tools, including DNA/RNA blotting and mult

193 tform for integrating SPR sensors with other bioanalytical tools.

194 compatibility of cascaded FF-IEF with common bioanalytical tools.

195 door to new applications for these important bioanalytical tools.

196 rticles is very important for affinity-based bioanalytical tools.

197 the discrete dispensing of biosamples into a bioanalytical unit.

198 L using 20 muL of plasma and met the regular bioanalytical validation requirements, both in the absen

199 linearity, accuracy, and precision data for bioanalytical validations with and without the inclusion

200 Bioanalytical verification requires both plasma generati

201 A bioanalytical workflow involving streptavidin chromatogr