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1 identity change, we performed mutational and biochemical experiments.
2 llowing immediate use of the modified RNA in biochemical experiments.
3 ther characterized by additional genetic and biochemical experiments.
4 e used in a myriad of diverse biological and biochemical experiments.
5 centration is an essential component of most biochemical experiments.
6 gths similar to those obtained from ensemble biochemical experiments.
7 characterized by an array of biophysical and biochemical experiments.
8 f its catalytic role, consistent with recent biochemical experiments.
9 ty of this interaction was confirmed through biochemical experiments.
10  3 mM, consistent with extensive independent biochemical experiments.
11  providing hypotheses for future genetic and biochemical experiments.
12 units, we performed electrophysiological and biochemical experiments.
13 hanism are usually inferred from a series of biochemical experiments.
14  segments in reasonable quantity facilitates biochemical experiments.
15 system that can be used in a wide variety of biochemical experiments.
16  other single-molecule rotation and ensemble biochemical experiments.
17 diated molecular switch, which we confirm by biochemical experiments.
18 ing activity of CP and promotes uncapping in biochemical experiments.
19 hotocrosslinking of subunits, as assessed by biochemical experiments.
20  a nonspecific manner, which is confirmed in biochemical experiments.
21 reduced to the small proton flux measured in biochemical experiments.
22 ins to follow protein expression and perform biochemical experiments.
23            On the basis of these genetic and biochemical experiments, a biosynthetic pathway for BE-7
24                                              Biochemical experiments also demonstrated that, although
25                 Consistent with our previous biochemical experiments, analysis of the culture medium
26 r of wild-type and mutant CaMKIV proteins in biochemical experiments and cellular transcriptional ass
27                             A combination of biochemical experiments and computer simulations shows t
28                                     Although biochemical experiments and cryo-electron microscopy dat
29 f single metabolite can vary greatly between biochemical experiments and even between instrument runs
30                                              Biochemical experiments and genomic sequence analysis sh
31       The proposed mechanism is supported by biochemical experiments and is consistent with the effec
32                                              Biochemical experiments and molecular dynamics simulatio
33                                     Finally, biochemical experiments and predictions show that initia
34                                              Biochemical experiments and proteomic analysis of the pu
35                                      Further biochemical experiments and structural analysis show tha
36 of the depupylase Dop using a combination of biochemical experiments and X-ray crystallographic studi
37 poptosome components, elegant structural and biochemical experiments, and analyses of the apoptosome
38                        Sequence comparisons, biochemical experiments, and studies with mutants in tra
39                  Here we show the results of biochemical experiments as follows: (i) we demonstrate t
40                                          The biochemical experiments assessing the hydrolysis of seve
41                                           In biochemical experiments both phosphatases were able to r
42 sired results are achieved, or computed from biochemical experiments carried out in vitro.
43         We characterize these residues using biochemical experiments combined with high-resolution cr
44                              Mutagenesis and biochemical experiments confirm that C-terminal residues
45 fully formed only in the binary complex, and biochemical experiments confirm this induced-fit behavio
46                                              Biochemical experiments confirm this interaction.
47                                              Biochemical experiments confirmed direct CADTK phosphory
48                          Focused genetic and biochemical experiments confirmed several conjectures ab
49                                              Biochemical experiments confirmed that some of these Pre
50                                              Biochemical experiments confirmed that the selected pept
51                                  Genetic and biochemical experiments consistently demonstrated that t
52                                        Here, biochemical experiments critical to testing this model w
53 usekeeping roles in Streptomyces avermitilis Biochemical experiments define the attributes of an opti
54                                          Our biochemical experiments defined the C. elegans cohesin c
55             Thus, the results of genetic and biochemical experiments demonstrate that CDC25R1489E enc
56                                  Genetic and biochemical experiments demonstrate that increased flux
57                                   Additional biochemical experiments demonstrate that intact MAGUKs d
58 h in vivo and in vitro ChIP-Seq analysis and biochemical experiments demonstrate that modulation of S
59 on of rsbN causes precocious sporulation and biochemical experiments demonstrate that RsbN functions
60                                              Biochemical experiments demonstrate that stabilization o
61                                        These biochemical experiments demonstrate that the anti-APC pe
62                                Complementary biochemical experiments demonstrate that the core U2AF h
63                                      NMR and biochemical experiments demonstrate that the OCRE domain
64 t Pkd1l1 and Pkd2 localise to the cilium and biochemical experiments demonstrate that they can physic
65  Polycomb complex 2 (PRC2) and H3K27me3, and biochemical experiments demonstrate the ability of RBFox
66                                              Biochemical experiments demonstrate the presence of AsnR
67                                 In addition, biochemical experiments demonstrated increased expressio
68                                              Biochemical experiments demonstrated that Dam1p binds di
69                               Structural and biochemical experiments demonstrated that nsp11 exists m
70                                              Biochemical experiments demonstrated that PHF11 stimulat
71 rescence cross-correlation spectroscopy, and biochemical experiments demonstrated that the formation
72                                              Biochemical experiments demonstrated that the luminal do
73          Cell culture aggregation assays and biochemical experiments demonstrated the ability of Neur
74                                              Biochemical experiments demonstrated the occurrence of b
75     In this report we present structural and biochemical experiments demonstrating that formation of
76 protein function from sequence is useful for biochemical experiment design, mutagenesis analysis, pro
77  U2AF subunits associate in a tight complex, biochemical experiments designed to address the requirem
78 hich have also become indispensable tools in biochemical experiments designed to probe antagonist bin
79                                              Biochemical experiments determined that Jak2 and tubulin
80                          Pharmacological and biochemical experiments determined that the IC50 values
81                                              Biochemical experiments establish a direct physical inte
82       Resequencing, expression analysis, and biochemical experiments focused on one such locus (CYP39
83 it can be used to develop hypotheses guiding biochemical experiments for establishing the role of the
84                                          Our biochemical experiments further show that Sven6563 has a
85                                              Biochemical experiments further validate our model for F
86 1 based on genetic evidence, but conflicting biochemical experiments have created uncertainty regardi
87                                       Recent biochemical experiments have demonstrated that in the pr
88                                  Genetic and biochemical experiments have demonstrated that the genes
89                                              Biochemical experiments have established that the metabo
90                                  Genetic and biochemical experiments have found that increased modifi
91                                       Recent biochemical experiments have implicated protein kinase C
92                                     Although biochemical experiments have implicated RecJ exonuclease
93                                 In vitro and biochemical experiments have implicated tyrosine kinases
94                                     Numerous biochemical experiments have invoked a model in which B-
95                                  Independent biochemical experiments have shown that MotCF binds to o
96                                              Biochemical experiments have shown that myosin-I membran
97                              Concordant with biochemical experiments, however, MKK4 occupied compartm
98                       Computing analysis and biochemical experiments identified that constitutive Anx
99         Consistent with this interpretation, biochemical experiments identify the upstream MAPKKKs Sl
100                                              Biochemical experiments illuminated a mechanism of inter
101                                 Accompanying biochemical experiments illustrate that NP indeed has a
102                                  Genetic and biochemical experiments implicate RecJ exonuclease in ho
103 crofluidic circuits that are able to perform biochemical experiments in a parallel and autonomous man
104 roteins have been well characterized through biochemical experiments in metazoans, their functions in
105 tic KRPs in yeast and Drosophila, as well as biochemical experiments in other species, have suggested
106        We explain observations from previous biochemical experiments in the light of results obtained
107                      Structural modeling and biochemical experiments in vitro have implicated a multi
108                                              Biochemical experiments in vitro indicate that secreted
109 e T362I RdRp exhibits a mutator phenotype in biochemical experiments in vitro.
110                                              Biochemical experiments in yeast suggest a possible mech
111                                              Biochemical experiments including site-directed mutants
112                                  Genetic and biochemical experiments, including artificial induction
113 can be used for a variety of biophysical and biochemical experiments, including studies of DNA repair
114                                              Biochemical experiments indicate that activator proteins
115                                      S2 cell biochemical experiments indicate that bantam regulates t
116                           Colocalization and biochemical experiments indicate that Barren associates
117                                              Biochemical experiments indicate that Bdf1 competes with
118                                              Biochemical experiments indicate that both catalyze fork
119                                              Biochemical experiments indicate that Ing4 is a subunit
120                                              Biochemical experiments indicate that peptides bound in
121        Genetic analysis, colocalization, and biochemical experiments indicate that Prm3p interacts di
122                                              Biochemical experiments indicate that RECQL4 specificall
123                                              Biochemical experiments indicate that Rgr has GTP/GDP ex
124                                  Genetic and biochemical experiments indicate that Rrp6p interacts wi
125                                              Biochemical experiments indicate that Ruml potently inhi
126                              Further, recent biochemical experiments indicate that the Aux/IAA protei
127                                              Biochemical experiments indicate that the basic function
128                                              Biochemical experiments indicate that the charge state o
129            Chromatin immunoprecipitation and biochemical experiments indicate that the chromodomain o
130                                              Biochemical experiments indicate that the general transc
131 he conserved nuclease domains, and extensive biochemical experiments indicate that the substrate spec
132                                              Biochemical experiments indicate that transcriptional el
133                                  Genetic and biochemical experiments indicate that Ybp1 is rate-limit
134                                              Biochemical experiments indicated a specific interaction
135                                              Biochemical experiments indicated that Sec3p directly in
136                      Limited proteolysis and biochemical experiments indicated that the coat protein
137                                  A series of biochemical experiments indicated that these miniprotein
138 f the Ca2+ sensor region (Cas) determined in biochemical experiments is equal to 0.23 microM Ca2+ for
139 phosphorylation site, observed previously in biochemical experiments, is enabled by a network of cons
140            Using a series of biophysical and biochemical experiments, it has been demonstrated that t
141                                        Early biochemical experiments measuring nearest neighbor frequ
142 ed in helices 90 and 92 were consistent with biochemical experiments measuring the RNA binding and AT
143 rophysiological and fluorescence recordings, biochemical experiments, mutagenesis and molecular dynam
144               Nuclear magnetic resonance and biochemical experiments now show that Tlg2p and Pep12p,
145 ide redox switch in the human BK channel and biochemical experiments of heme, CO, and HO2 binding to
146                                           In biochemical experiments on MsbA from Escherichia coli, w
147                In this study, based on prior biochemical experiments on VKC and VKOR, we propose a he
148                                  Genetic and biochemical experiments over the past decade have identi
149 tails of FtsY recruitment and, together with biochemical experiments, pinpoints G83 as the key RNA re
150                                  Genetic and biochemical experiments previously demonstrated that the
151                      Together, these NMR and biochemical experiments provide additional insight into
152            The results, together with recent biochemical experiments, provide support for a mechanism
153 nction and provide information for designing biochemical experiments require knowledge of the complet
154           Moreover, in vivo interference and biochemical experiments reveal a key function for multip
155                                              Biochemical experiments reveal that the Rgf3 C-terminus
156                       Immunofluorescence and biochemical experiments reveal that this redistribution
157                       Additional genetic and biochemical experiments revealed a close relationship be
158 tracellular GABA complemented by a series of biochemical experiments revealed a reduction of GAT acti
159                    Combined cell imaging and biochemical experiments revealed a robust increase in th
160                              Structure-based biochemical experiments revealed additional determinants
161                                    Moreover, biochemical experiments revealed an association of the a
162       Furthermore, whole-cell recordings and biochemical experiments revealed direct SVZ NSC response
163                                              Biochemical experiments revealed that cortactin co-immun
164                                 Our parallel biochemical experiments revealed that inductions of the
165                                              Biochemical experiments revealed that Lnk directly binds
166                                              Biochemical experiments revealed that RGS7 binds to a co
167                                  Genetic and biochemical experiments revealed that the epidermal grow
168 tion of nuclear magnetic resonance (NMR) and biochemical experiments revealed that the minimal acidic
169                                              Biochemical experiments revealed that the Perd intracell
170                                  A series of biochemical experiments revealed that the variation in f
171                                              Biochemical experiments revealed that TLR11 and TLR12 di
172         The crystal structure, together with biochemical experiments, reveals an unexpected four-stra
173                  Our structure, supported by biochemical experiments, reveals that the SRP RNA adopts
174                                              Biochemical experiments show Dhh1p is preferentially ass
175                                              Biochemical experiments show that an IcmF in which the b
176                                              Biochemical experiments show that CDH23 homodimers inter
177                                              Biochemical experiments show that coatomer directly part
178                                     However, biochemical experiments show that PATJ associates with b
179                                              Biochemical experiments show that peptides from ALIX and
180                                              Biochemical experiments show that PKD2 physically intera
181                                Nevertheless, biochemical experiments show that scaRNAs are present at
182                                  Genetic and biochemical experiments show that sigma(E) activity is u
183                                              Biochemical experiments show that SmpA is involved in ma
184                                              Biochemical experiments show that the purified kinase in
185         Isothermal titration calorimetry and biochemical experiments show that the two Ca(2+)/CaMs in
186 essary and sufficient for VP1 binding, while biochemical experiments show that VP3 attachment has no
187                                          Our biochemical experiments show that WRN and DNA2 interact
188                                  Genetic and biochemical experiments show that, when released from th
189                                              Biochemical experiments showed that constitutive phospho
190 orescent protein-DIM/DWF1 fusion protein and biochemical experiments showed that DIM/DWF1 is an integ
191                                  Genetic and biochemical experiments showed that EcfO was located in
192             Consistent with this prediction, biochemical experiments showed that PAGE4 preferentially
193                                              Biochemical experiments showed that Rac1 associates with
194                            Physiological and biochemical experiments showed that rods from mice with
195                                              Biochemical experiments showed that the major PDGFbetaR
196        Thus, these structures explain recent biochemical experiments showing that M. jannaschii ProRS
197                               Here we report biochemical experiments showing that PF-3450074 (PF74),
198                                              Biochemical experiments suggest how scanning and engagem
199 present study, together with our preliminary biochemical experiments suggest that catecholaminergic a
200            Results from crystallographic and biochemical experiments suggest that CF I(m)25 makes use
201                    Genetic, cytological, and biochemical experiments suggest that Clp1p/Flp1p functio
202                                              Biochemical experiments suggest that general acid cataly
203                  Structural, mechanical, and biochemical experiments suggest that in order not to let
204                                              Biochemical experiments suggest that only CETP can trans
205                                              Biochemical experiments suggest that several warfarin-re
206                                              Biochemical experiments suggest that TFIIA is important
207                          Because genetic and biochemical experiments suggest that the processes of br
208                                              Biochemical experiments suggest that VPS41 functions in
209 oxic lesion 3-methyladenine and accompanying biochemical experiments suggested that AlkA actively int
210                                              Biochemical experiments suggested that BLM resides in a
211                               Microscopy and biochemical experiments suggested that expression of KMS
212                               Functional and biochemical experiments suggested that PINS and BINS are
213                                              Biochemical experiments support a directional sliding of
214                                   Additional biochemical experiments support a model whereby a single
215                                  Genetic and biochemical experiments support a structural arrangement
216                                        These biochemical experiments support the idea that yeast poly
217                         RNA interference and biochemical experiments support the model that ephrin-B3
218 n transcriptional analysis are indirect, but biochemical experiments supported some of these deductio
219 remains uncertain with electrophysiology and biochemical experiments supporting both a tetramer with
220                         Structural analysis, biochemical experiments, surface electrostatics, and seq
221                                We now report biochemical experiments testing the interaction of E. co
222 demonstrate in cell culture, in vivo, and in biochemical experiments that Akt regulation by Par-4 is
223            These results support genetic and biochemical experiments that have implicated Bcl10 and i
224 ure of the Kv7.4 A-domain Tail together with biochemical experiments that show that the domain is a s
225 ensional crystal structures and results from biochemical experiments, the phenotypes produced by thes
226 otein complexes have been identified through biochemical experiments, the precise molecular details a
227                                Together with biochemical experiments, these data indicate that MTF1 u
228 ducin (PDC) has been shown in structural and biochemical experiments to bind the Gbetagamma subunit o
229 dings, we present mass spectrometry data and biochemical experiments to demonstrate that this lysine
230         Here we use single-molecule and bulk biochemical experiments to determine how Cas9-RNA interr
231 the relatively much slower progress in using biochemical experiments to determine their functions, it
232 d on these structural features, we performed biochemical experiments to examine the interactions of D
233 roprotective drug and carried out additional biochemical experiments to identify its mechanism of act
234 ased expression platform along with in vitro biochemical experiments to identify the enzyme that cata
235                                              Biochemical experiments to isolate pUL6 were carried out
236 has also been implicated through genetic and biochemical experiments to play a role in DNA repair pro
237                      Here we use genetic and biochemical experiments to show that the essential ATPas
238  proteins and performed in vitro and in vivo biochemical experiments to test the physical model.
239 t al. (2017) use advanced mouse genetics and biochemical experiments to unravel the ligand-specific a
240       Here we used a combination of in vitro biochemical experiments together with phylogenetic compa
241                                  A series of biochemical experiments tracked the specific location of
242                      Exposure to genetic and biochemical experiments typically occurs late in one's a
243 more direct fashion, we designed a series of biochemical experiments using a modified version of the
244 ural work presented here in combination with biochemical experiments using artificial tRNA or artific
245                                      Because biochemical experiments using both purified RAG proteins
246                                              Biochemical experiments using Chd1p purified from yeast
247 dy of evidence derived largely from in vitro biochemical experiments using purified proteins, cell-fr
248                                           In biochemical experiments, UvrA bound to heteroduplex subs
249                               In a series of biochemical experiments we demonstrate the following fin
250 related proteins, but in similar genetic and biochemical experiments we fail to find evidence that Va
251                    Through embryological and biochemical experiments we find that: (1) CV2 functions
252                                           In biochemical experiments, we confirmed the specificity of
253                               In a series of biochemical experiments, we demonstrate a specific assoc
254                                           In biochemical experiments, we demonstrate that mutant ATX3
255                                Using various biochemical experiments, we demonstrate that the mechani
256                         Based on genetic and biochemical experiments, we establish that the UbiI prot
257 ing a combination of genetic, molecular, and biochemical experiments, we establish that, in the absen
258            Through protein fractionation and biochemical experiments, we find that Ku70/Ku80 and DNA-
259                Using mutational analysis and biochemical experiments, we have discovered a previously
260                            Using a series of biochemical experiments, we have studied protein-protein
261            In this study, using quantitative biochemical experiments, we have tested the role of a li
262 Based on structural analyses and genetic and biochemical experiments, we identify an alpha-helical sw
263 electron microscopy (EM), bioinformatics and biochemical experiments, we identify two highly conserve
264                            To complement the biochemical experiments, we investigated the effects of
265 ation spectroscopy, respectively) as well as biochemical experiments, we obtained two novel findings;
266  and sequencing (ChIP-seq) and complementary biochemical experiments, we show that AR-Vs display a bi
267 RAP) and photoactivatable probes, coupled to biochemical experiments, we show that COPI subunit delta
268 omparisons to dynamin knock-out synapses and biochemical experiments, we suggest that synucleins act
269                                  A series of biochemical experiments were carried out to characterize
270                                              Biochemical experiments were used to examine point mutat
271 P are validated in extensive mutagenesis and biochemical experiments, which also provide a thorough c
272                                              Biochemical experiments with Acf1-deficient embryo extra
273  interpreting the results of mutagenesis and biochemical experiments with ArgR.
274  Here we employed computational modeling and biochemical experiments with model cell lines and thymoc
275                                     Based on biochemical experiments with modified oligonucleotides,
276  appeared to be much faster than observed in biochemical experiments with muscle actin.
277                   In this study, we combined biochemical experiments with observations in egg chamber
278                                              Biochemical experiments with purified recombinant protei
279                Here, based on the results of biochemical experiments with purified wild-type and vari
280 e ribosome provided significant insights but biochemical experiments with RelE were required to clear
281                                              Biochemical experiments with rhodopsin, cone visual pigm
282                                              Biochemical experiments with RNase PH demonstrated that
283                                              Biochemical experiments with the use of recombinant DLP1
284  in a form that is suitable for quantitative biochemical experiments with yields of 5 and 0.5 mg per
285 din/BMP-4 complexes at two specific sites in biochemical experiments Xolloid mRNA blocks secondary ax

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