1 identity change, we performed mutational and
biochemical experiments.
2 llowing immediate use of the modified RNA in
biochemical experiments.
3 ther characterized by additional genetic and
biochemical experiments.
4 e used in a myriad of diverse biological and
biochemical experiments.
5 centration is an essential component of most
biochemical experiments.
6 gths similar to those obtained from ensemble
biochemical experiments.
7 characterized by an array of biophysical and
biochemical experiments.
8 f its catalytic role, consistent with recent
biochemical experiments.
9 ty of this interaction was confirmed through
biochemical experiments.
10 3 mM, consistent with extensive independent
biochemical experiments.
11 providing hypotheses for future genetic and
biochemical experiments.
12 units, we performed electrophysiological and
biochemical experiments.
13 hanism are usually inferred from a series of
biochemical experiments.
14 segments in reasonable quantity facilitates
biochemical experiments.
15 system that can be used in a wide variety of
biochemical experiments.
16 other single-molecule rotation and ensemble
biochemical experiments.
17 diated molecular switch, which we confirm by
biochemical experiments.
18 ing activity of CP and promotes uncapping in
biochemical experiments.
19 hotocrosslinking of subunits, as assessed by
biochemical experiments.
20 a nonspecific manner, which is confirmed in
biochemical experiments.
21 reduced to the small proton flux measured in
biochemical experiments.
22 ins to follow protein expression and perform
biochemical experiments.
23 On the basis of these genetic and
biochemical experiments,
a biosynthetic pathway for BE-7
24 Biochemical experiments also demonstrated that, although
25 Consistent with our previous
biochemical experiments,
analysis of the culture medium
26 r of wild-type and mutant CaMKIV proteins in
biochemical experiments and cellular transcriptional ass
27 A combination of
biochemical experiments and computer simulations shows t
28 Although
biochemical experiments and cryo-electron microscopy dat
29 f single metabolite can vary greatly between
biochemical experiments and even between instrument runs
30 Biochemical experiments and genomic sequence analysis sh
31 The proposed mechanism is supported by
biochemical experiments and is consistent with the effec
32 Biochemical experiments and molecular dynamics simulatio
33 Finally,
biochemical experiments and predictions show that initia
34 Biochemical experiments and proteomic analysis of the pu
35 Further
biochemical experiments and structural analysis show tha
36 of the depupylase Dop using a combination of
biochemical experiments and X-ray crystallographic studi
37 poptosome components, elegant structural and
biochemical experiments,
and analyses of the apoptosome
38 Sequence comparisons,
biochemical experiments,
and studies with mutants in tra
39 Here we show the results of
biochemical experiments as follows: (i) we demonstrate t
40 The
biochemical experiments assessing the hydrolysis of seve
41 In
biochemical experiments both phosphatases were able to r
42 sired results are achieved, or computed from
biochemical experiments carried out in vitro.
43 We characterize these residues using
biochemical experiments combined with high-resolution cr
44 Mutagenesis and
biochemical experiments confirm that C-terminal residues
45 fully formed only in the binary complex, and
biochemical experiments confirm this induced-fit behavio
46 Biochemical experiments confirm this interaction.
47 Biochemical experiments confirmed direct CADTK phosphory
48 Focused genetic and
biochemical experiments confirmed several conjectures ab
49 Biochemical experiments confirmed that some of these Pre
50 Biochemical experiments confirmed that the selected pept
51 Genetic and
biochemical experiments consistently demonstrated that t
52 Here,
biochemical experiments critical to testing this model w
53 usekeeping roles in Streptomyces avermitilis
Biochemical experiments define the attributes of an opti
54 Our
biochemical experiments defined the C. elegans cohesin c
55 Thus, the results of genetic and
biochemical experiments demonstrate that CDC25R1489E enc
56 Genetic and
biochemical experiments demonstrate that increased flux
57 Additional
biochemical experiments demonstrate that intact MAGUKs d
58 h in vivo and in vitro ChIP-Seq analysis and
biochemical experiments demonstrate that modulation of S
59 on of rsbN causes precocious sporulation and
biochemical experiments demonstrate that RsbN functions
60 Biochemical experiments demonstrate that stabilization o
61 These
biochemical experiments demonstrate that the anti-APC pe
62 Complementary
biochemical experiments demonstrate that the core U2AF h
63 NMR and
biochemical experiments demonstrate that the OCRE domain
64 t Pkd1l1 and Pkd2 localise to the cilium and
biochemical experiments demonstrate that they can physic
65 Polycomb complex 2 (PRC2) and H3K27me3, and
biochemical experiments demonstrate the ability of RBFox
66 Biochemical experiments demonstrate the presence of AsnR
67 In addition,
biochemical experiments demonstrated increased expressio
68 Biochemical experiments demonstrated that Dam1p binds di
69 Structural and
biochemical experiments demonstrated that nsp11 exists m
70 Biochemical experiments demonstrated that PHF11 stimulat
71 rescence cross-correlation spectroscopy, and
biochemical experiments demonstrated that the formation
72 Biochemical experiments demonstrated that the luminal do
73 Cell culture aggregation assays and
biochemical experiments demonstrated the ability of Neur
74 Biochemical experiments demonstrated the occurrence of b
75 In this report we present structural and
biochemical experiments demonstrating that formation of
76 protein function from sequence is useful for
biochemical experiment design, mutagenesis analysis, pro
77 U2AF subunits associate in a tight complex,
biochemical experiments designed to address the requirem
78 hich have also become indispensable tools in
biochemical experiments designed to probe antagonist bin
79 Biochemical experiments determined that Jak2 and tubulin
80 Pharmacological and
biochemical experiments determined that the IC50 values
81 Biochemical experiments establish a direct physical inte
82 Resequencing, expression analysis, and
biochemical experiments focused on one such locus (CYP39
83 it can be used to develop hypotheses guiding
biochemical experiments for establishing the role of the
84 Our
biochemical experiments further show that Sven6563 has a
85 Biochemical experiments further validate our model for F
86 1 based on genetic evidence, but conflicting
biochemical experiments have created uncertainty regardi
87 Recent
biochemical experiments have demonstrated that in the pr
88 Genetic and
biochemical experiments have demonstrated that the genes
89 Biochemical experiments have established that the metabo
90 Genetic and
biochemical experiments have found that increased modifi
91 Recent
biochemical experiments have implicated protein kinase C
92 Although
biochemical experiments have implicated RecJ exonuclease
93 In vitro and
biochemical experiments have implicated tyrosine kinases
94 Numerous
biochemical experiments have invoked a model in which B-
95 Independent
biochemical experiments have shown that MotCF binds to o
96 Biochemical experiments have shown that myosin-I membran
97 Concordant with
biochemical experiments,
however, MKK4 occupied compartm
98 Computing analysis and
biochemical experiments identified that constitutive Anx
99 Consistent with this interpretation,
biochemical experiments identify the upstream MAPKKKs Sl
100 Biochemical experiments illuminated a mechanism of inter
101 Accompanying
biochemical experiments illustrate that NP indeed has a
102 Genetic and
biochemical experiments implicate RecJ exonuclease in ho
103 crofluidic circuits that are able to perform
biochemical experiments in a parallel and autonomous man
104 roteins have been well characterized through
biochemical experiments in metazoans, their functions in
105 tic KRPs in yeast and Drosophila, as well as
biochemical experiments in other species, have suggested
106 We explain observations from previous
biochemical experiments in the light of results obtained
107 Structural modeling and
biochemical experiments in vitro have implicated a multi
108 Biochemical experiments in vitro indicate that secreted
109 e T362I RdRp exhibits a mutator phenotype in
biochemical experiments in vitro.
110 Biochemical experiments in yeast suggest a possible mech
111 Biochemical experiments including site-directed mutants
112 Genetic and
biochemical experiments,
including artificial induction
113 can be used for a variety of biophysical and
biochemical experiments,
including studies of DNA repair
114 Biochemical experiments indicate that activator proteins
115 S2 cell
biochemical experiments indicate that bantam regulates t
116 Colocalization and
biochemical experiments indicate that Barren associates
117 Biochemical experiments indicate that Bdf1 competes with
118 Biochemical experiments indicate that both catalyze fork
119 Biochemical experiments indicate that Ing4 is a subunit
120 Biochemical experiments indicate that peptides bound in
121 Genetic analysis, colocalization, and
biochemical experiments indicate that Prm3p interacts di
122 Biochemical experiments indicate that RECQL4 specificall
123 Biochemical experiments indicate that Rgr has GTP/GDP ex
124 Genetic and
biochemical experiments indicate that Rrp6p interacts wi
125 Biochemical experiments indicate that Ruml potently inhi
126 Further, recent
biochemical experiments indicate that the Aux/IAA protei
127 Biochemical experiments indicate that the basic function
128 Biochemical experiments indicate that the charge state o
129 Chromatin immunoprecipitation and
biochemical experiments indicate that the chromodomain o
130 Biochemical experiments indicate that the general transc
131 he conserved nuclease domains, and extensive
biochemical experiments indicate that the substrate spec
132 Biochemical experiments indicate that transcriptional el
133 Genetic and
biochemical experiments indicate that Ybp1 is rate-limit
134 Biochemical experiments indicated a specific interaction
135 Biochemical experiments indicated that Sec3p directly in
136 Limited proteolysis and
biochemical experiments indicated that the coat protein
137 A series of
biochemical experiments indicated that these miniprotein
138 f the Ca2+ sensor region (Cas) determined in
biochemical experiments is equal to 0.23 microM Ca2+ for
139 phosphorylation site, observed previously in
biochemical experiments,
is enabled by a network of cons
140 Using a series of biophysical and
biochemical experiments,
it has been demonstrated that t
141 Early
biochemical experiments measuring nearest neighbor frequ
142 ed in helices 90 and 92 were consistent with
biochemical experiments measuring the RNA binding and AT
143 rophysiological and fluorescence recordings,
biochemical experiments,
mutagenesis and molecular dynam
144 Nuclear magnetic resonance and
biochemical experiments now show that Tlg2p and Pep12p,
145 ide redox switch in the human BK channel and
biochemical experiments of heme, CO, and HO2 binding to
146 In
biochemical experiments on MsbA from Escherichia coli, w
147 In this study, based on prior
biochemical experiments on VKC and VKOR, we propose a he
148 Genetic and
biochemical experiments over the past decade have identi
149 tails of FtsY recruitment and, together with
biochemical experiments,
pinpoints G83 as the key RNA re
150 Genetic and
biochemical experiments previously demonstrated that the
151 Together, these NMR and
biochemical experiments provide additional insight into
152 The results, together with recent
biochemical experiments,
provide support for a mechanism
153 nction and provide information for designing
biochemical experiments require knowledge of the complet
154 Moreover, in vivo interference and
biochemical experiments reveal a key function for multip
155 Biochemical experiments reveal that the Rgf3 C-terminus
156 Immunofluorescence and
biochemical experiments reveal that this redistribution
157 Additional genetic and
biochemical experiments revealed a close relationship be
158 tracellular GABA complemented by a series of
biochemical experiments revealed a reduction of GAT acti
159 Combined cell imaging and
biochemical experiments revealed a robust increase in th
160 Structure-based
biochemical experiments revealed additional determinants
161 Moreover,
biochemical experiments revealed an association of the a
162 Furthermore, whole-cell recordings and
biochemical experiments revealed direct SVZ NSC response
163 Biochemical experiments revealed that cortactin co-immun
164 Our parallel
biochemical experiments revealed that inductions of the
165 Biochemical experiments revealed that Lnk directly binds
166 Biochemical experiments revealed that RGS7 binds to a co
167 Genetic and
biochemical experiments revealed that the epidermal grow
168 tion of nuclear magnetic resonance (NMR) and
biochemical experiments revealed that the minimal acidic
169 Biochemical experiments revealed that the Perd intracell
170 A series of
biochemical experiments revealed that the variation in f
171 Biochemical experiments revealed that TLR11 and TLR12 di
172 The crystal structure, together with
biochemical experiments,
reveals an unexpected four-stra
173 Our structure, supported by
biochemical experiments,
reveals that the SRP RNA adopts
174 Biochemical experiments show Dhh1p is preferentially ass
175 Biochemical experiments show that an IcmF in which the b
176 Biochemical experiments show that CDH23 homodimers inter
177 Biochemical experiments show that coatomer directly part
178 However,
biochemical experiments show that PATJ associates with b
179 Biochemical experiments show that peptides from ALIX and
180 Biochemical experiments show that PKD2 physically intera
181 Nevertheless,
biochemical experiments show that scaRNAs are present at
182 Genetic and
biochemical experiments show that sigma(E) activity is u
183 Biochemical experiments show that SmpA is involved in ma
184 Biochemical experiments show that the purified kinase in
185 Isothermal titration calorimetry and
biochemical experiments show that the two Ca(2+)/CaMs in
186 essary and sufficient for VP1 binding, while
biochemical experiments show that VP3 attachment has no
187 Our
biochemical experiments show that WRN and DNA2 interact
188 Genetic and
biochemical experiments show that, when released from th
189 Biochemical experiments showed that constitutive phospho
190 orescent protein-DIM/DWF1 fusion protein and
biochemical experiments showed that DIM/DWF1 is an integ
191 Genetic and
biochemical experiments showed that EcfO was located in
192 Consistent with this prediction,
biochemical experiments showed that PAGE4 preferentially
193 Biochemical experiments showed that Rac1 associates with
194 Physiological and
biochemical experiments showed that rods from mice with
195 Biochemical experiments showed that the major PDGFbetaR
196 Thus, these structures explain recent
biochemical experiments showing that M. jannaschii ProRS
197 Here we report
biochemical experiments showing that PF-3450074 (PF74),
198 Biochemical experiments suggest how scanning and engagem
199 present study, together with our preliminary
biochemical experiments suggest that catecholaminergic a
200 Results from crystallographic and
biochemical experiments suggest that CF I(m)25 makes use
201 Genetic, cytological, and
biochemical experiments suggest that Clp1p/Flp1p functio
202 Biochemical experiments suggest that general acid cataly
203 Structural, mechanical, and
biochemical experiments suggest that in order not to let
204 Biochemical experiments suggest that only CETP can trans
205 Biochemical experiments suggest that several warfarin-re
206 Biochemical experiments suggest that TFIIA is important
207 Because genetic and
biochemical experiments suggest that the processes of br
208 Biochemical experiments suggest that VPS41 functions in
209 oxic lesion 3-methyladenine and accompanying
biochemical experiments suggested that AlkA actively int
210 Biochemical experiments suggested that BLM resides in a
211 Microscopy and
biochemical experiments suggested that expression of KMS
212 Functional and
biochemical experiments suggested that PINS and BINS are
213 Biochemical experiments support a directional sliding of
214 Additional
biochemical experiments support a model whereby a single
215 Genetic and
biochemical experiments support a structural arrangement
216 These
biochemical experiments support the idea that yeast poly
217 RNA interference and
biochemical experiments support the model that ephrin-B3
218 n transcriptional analysis are indirect, but
biochemical experiments supported some of these deductio
219 remains uncertain with electrophysiology and
biochemical experiments supporting both a tetramer with
220 Structural analysis,
biochemical experiments,
surface electrostatics, and seq
221 We now report
biochemical experiments testing the interaction of E. co
222 demonstrate in cell culture, in vivo, and in
biochemical experiments that Akt regulation by Par-4 is
223 These results support genetic and
biochemical experiments that have implicated Bcl10 and i
224 ure of the Kv7.4 A-domain Tail together with
biochemical experiments that show that the domain is a s
225 ensional crystal structures and results from
biochemical experiments,
the phenotypes produced by thes
226 otein complexes have been identified through
biochemical experiments,
the precise molecular details a
227 Together with
biochemical experiments,
these data indicate that MTF1 u
228 ducin (PDC) has been shown in structural and
biochemical experiments to bind the Gbetagamma subunit o
229 dings, we present mass spectrometry data and
biochemical experiments to demonstrate that this lysine
230 Here we use single-molecule and bulk
biochemical experiments to determine how Cas9-RNA interr
231 the relatively much slower progress in using
biochemical experiments to determine their functions, it
232 d on these structural features, we performed
biochemical experiments to examine the interactions of D
233 roprotective drug and carried out additional
biochemical experiments to identify its mechanism of act
234 ased expression platform along with in vitro
biochemical experiments to identify the enzyme that cata
235 Biochemical experiments to isolate pUL6 were carried out
236 has also been implicated through genetic and
biochemical experiments to play a role in DNA repair pro
237 Here we use genetic and
biochemical experiments to show that the essential ATPas
238 proteins and performed in vitro and in vivo
biochemical experiments to test the physical model.
239 t al. (2017) use advanced mouse genetics and
biochemical experiments to unravel the ligand-specific a
240 Here we used a combination of in vitro
biochemical experiments together with phylogenetic compa
241 A series of
biochemical experiments tracked the specific location of
242 Exposure to genetic and
biochemical experiments typically occurs late in one's a
243 more direct fashion, we designed a series of
biochemical experiments using a modified version of the
244 ural work presented here in combination with
biochemical experiments using artificial tRNA or artific
245 Because
biochemical experiments using both purified RAG proteins
246 Biochemical experiments using Chd1p purified from yeast
247 dy of evidence derived largely from in vitro
biochemical experiments using purified proteins, cell-fr
248 In
biochemical experiments,
UvrA bound to heteroduplex subs
249 In a series of
biochemical experiments we demonstrate the following fin
250 related proteins, but in similar genetic and
biochemical experiments we fail to find evidence that Va
251 Through embryological and
biochemical experiments we find that: (1) CV2 functions
252 In
biochemical experiments,
we confirmed the specificity of
253 In a series of
biochemical experiments,
we demonstrate a specific assoc
254 In
biochemical experiments,
we demonstrate that mutant ATX3
255 Using various
biochemical experiments,
we demonstrate that the mechani
256 Based on genetic and
biochemical experiments,
we establish that the UbiI prot
257 ing a combination of genetic, molecular, and
biochemical experiments,
we establish that, in the absen
258 Through protein fractionation and
biochemical experiments,
we find that Ku70/Ku80 and DNA-
259 Using mutational analysis and
biochemical experiments,
we have discovered a previously
260 Using a series of
biochemical experiments,
we have studied protein-protein
261 In this study, using quantitative
biochemical experiments,
we have tested the role of a li
262 Based on structural analyses and genetic and
biochemical experiments,
we identify an alpha-helical sw
263 electron microscopy (EM), bioinformatics and
biochemical experiments,
we identify two highly conserve
264 To complement the
biochemical experiments,
we investigated the effects of
265 ation spectroscopy, respectively) as well as
biochemical experiments,
we obtained two novel findings;
266 and sequencing (ChIP-seq) and complementary
biochemical experiments,
we show that AR-Vs display a bi
267 RAP) and photoactivatable probes, coupled to
biochemical experiments,
we show that COPI subunit delta
268 omparisons to dynamin knock-out synapses and
biochemical experiments,
we suggest that synucleins act
269 A series of
biochemical experiments were carried out to characterize
270 Biochemical experiments were used to examine point mutat
271 P are validated in extensive mutagenesis and
biochemical experiments,
which also provide a thorough c
272 Biochemical experiments with Acf1-deficient embryo extra
273 interpreting the results of mutagenesis and
biochemical experiments with ArgR.
274 Here we employed computational modeling and
biochemical experiments with model cell lines and thymoc
275 Based on
biochemical experiments with modified oligonucleotides,
276 appeared to be much faster than observed in
biochemical experiments with muscle actin.
277 In this study, we combined
biochemical experiments with observations in egg chamber
278 Biochemical experiments with purified recombinant protei
279 Here, based on the results of
biochemical experiments with purified wild-type and vari
280 e ribosome provided significant insights but
biochemical experiments with RelE were required to clear
281 Biochemical experiments with rhodopsin, cone visual pigm
282 Biochemical experiments with RNase PH demonstrated that
283 Biochemical experiments with the use of recombinant DLP1
284 in a form that is suitable for quantitative
biochemical experiments with yields of 5 and 0.5 mg per
285 din/BMP-4 complexes at two specific sites in
biochemical experiments Xolloid mRNA blocks secondary ax