ライフサイエンスコーパス: biochemical mechanism

1 that is rooted in non-linear descriptions of biochemical mechanism.

2 cells is based on a biophysical as well as a biochemical mechanism.

3 known about its molecular components and its biochemical mechanism.

4 wn for decades, hindering elucidation of the biochemical mechanism.

5 to selectively perturb or probe these basic biochemical mechanisms.

6 pulsivity in adulthood and examined possible biochemical mechanisms.

7 hallenges of "systems biology" as applied to biochemical mechanisms.

8 ing regulators that act through a variety of biochemical mechanisms.

9 odynamics and to delineate the corresponding biochemical mechanisms.

10 areas for inquiry of basic physiological and biochemical mechanisms.

11 We propose a biochemical mechanism accounting for the dependency of m

12 A biochemical mechanism accounting for the Raman red shift

13 Biochemical mechanisms accounting for direct participati

14 While biochemical mechanisms activating actin network assembly

15 tween NGAL and its cellular receptor or in a biochemical mechanism allowing the receptor to discrimin

16 n in the nucleus may not be due to random or biochemical mechanisms alone, but may result from the tr

17 Small GTPases share a biochemical mechanism and act as binary molecular switch

18 However, the biochemical mechanism and determinants of R-loop formati

19 mechanisms of action that are independent of biochemical mechanism and have implications for biomarke

20 i1-mediated actin assembly in vitro, but the biochemical mechanism and in vivo role of this activity

21 led by cell-cycle-dependent factors, but its biochemical mechanism and spatial regulation remain poor

22 m biology is the study of quantum effects on biochemical mechanisms and biological function.

23 We also show that biochemical mechanisms and parameters together determine

24 The identification of biochemical mechanisms and prediction of patients at ris

25 little is known about LGR5 signaling nor the biochemical mechanisms and receptor determinants that re

26 ance and dependence are mediated by multiple biochemical mechanisms and that MOR endocytosis plays a

27 distinguishing feature of brown-rot, but the biochemical mechanisms and underlying genetics are poorl

28 ulation of UVB-induced COX-2, the underlying biochemical mechanisms are completely unknown.

29 of statin on the vascular functions, but the biochemical mechanisms are incompletely understood.

30 However, the underlying biochemical mechanisms are not known.

31 mpeting models arises commonly as underlying biochemical mechanisms are often not fully known, hence

32 Heterogeneous intracellular pathways and biochemical mechanisms are responsible for generating th

33 PUFA) may protect against breast cancer but biochemical mechanisms are unclear.

34 covery because their domain compositions and biochemical mechanisms are unique compared to the mammal

35 Because many of the biochemical mechanisms are unknown, this is a preliminar

36 ination in immune signaling pathways and the biochemical mechanisms as to how linear polyubiquitin ex

37 alytical tools capable of characterizing the biochemical mechanisms associated with chemically induce

38 s become possible to more precisely tune the biochemical mechanisms associated with using nonviral ve

39 nteractions is fundamental for understanding biochemical mechanisms at the molecular level.

40 rch and faces challenges, mainly because the biochemical mechanisms behind the cancer-related VOCs ar

41 We have analyzed the underlying biochemical mechanism by carrying out alanine-scanning m

42 P-pVIc complexes along DNA illustrates a new biochemical mechanism by which a proteinase can locate i

43 there is a paucity of data available on the biochemical mechanism by which APOBEC3A deaminates ssDNA

44 together, these results demonstrate a novel biochemical mechanism by which ascorbate oxidation and t

45 In this study, we investigate the biochemical mechanism by which ATF6alpha activates trans

46 However, little is known about the biochemical mechanism by which BIN2 phosphorylates its s

47 However, the biochemical mechanism by which E3 ubiquitination is impa

48 that controls axon pruning and elucidate the biochemical mechanism by which ephrin-B reverse signals

49 Together, these results identify a direct biochemical mechanism by which Gadd45a induces skeletal

50 However, the biochemical mechanism by which IreB modulates cephalospo

51 e silencing, little is known of the specific biochemical mechanism by which it inactivates transcript

52 The biochemical mechanism by which mutations in nucleotide-b

53 min in human endothelial cells (ECs) and the biochemical mechanism by which neurofibromin regulates n

54 ponents, we demonstrate for the first time a biochemical mechanism by which Src phosphorylation of co

55 efore, our study provides the first feasible biochemical mechanism by which the +1166 A/C polymorphis

56 These results define a biochemical mechanism by which the BRCA1 enzymatic activ

57 A biochemical mechanism by which these transcription facto

58 However, the biochemical mechanism by which they cause immune dysfunc

59 The biochemical mechanism by which this single molecule cont

60 Here we dissected the biochemical mechanism by which TLR5 engagement mediates

61 This study examined the biochemical mechanism by which vitamin D supplementation

62 n this study, we have begun to elucidate the biochemical mechanisms by which BTLA functions to inhibi

63 The structural and biochemical mechanisms by which EBNA1 allows the long-te

64 n implicated in many cellular processes, the biochemical mechanisms by which it influences these dive

65 provides a powerful tool to investigate the biochemical mechanisms by which lysine methylation influ

66 te mitochondria-mediated cell death, but the biochemical mechanisms by which other factors promote or

67 However, biochemical mechanisms by which plants counteract NP tox

68 To gain insights into the biochemical mechanisms by which RON inhibits transcripti

69 sphatases to PD-1, little is known about the biochemical mechanisms by which these proteins contribut

70 These studies define cellular and biochemical mechanisms by which Vms1 locali-zation to mi

71 The biochemical mechanism comprising signal transfer from ph

72 These findings uncover a conserved biochemical mechanism coupling nutrient status with auto

73 n of CheBs in pheromone response may involve biochemical mechanisms critical for lipid metabolism in

74 These results reveal a biochemical mechanism differentiating the endocytic acti

75 ivates these two related targets by the same biochemical mechanism: direct phosphorylation of a conse

76 While knowledge of the biochemical mechanisms driving this process has accumula

77 and illustrate the sophisticated variety of biochemical mechanisms employed in fine-tuning its redox

78 orted in plants, little is known about their biochemical mechanisms, especially their relationships w

79 f intracellular pathogens in addition to the biochemical mechanisms examined here.

80 bulky DNA adducts, we conclude that a common biochemical mechanism exists for activation of DNA-PK, A

81 ofacial and limb development and providing a biochemical mechanism for additive signaling requirement

82 cross multiple clonal processes and define a biochemical mechanism for altered 3'SS choice.

83 ther, these results establish a novel direct biochemical mechanism for ASMase activation in which PKC

84 pathway in BRAF(WT) cells but also offers a biochemical mechanism for BRAF oncogenesis.

85 The phosphoswitch provides a biochemical mechanism for circadian temperature compensa

86 ing residue was C315(7.38) and suggested one biochemical mechanism for covalent binding.

87 mage and, therefore, provide a new plausible biochemical mechanism for diabetic cardiomyopathy.

88 We examined here the biochemical mechanism for directional strand passage of

89 Here, we demonstrate a distinct biochemical mechanism for DNA break processing employed

90 We support our data with a plausible biochemical mechanism for modified bioenergetics that in

91 This provides a biochemical mechanism for MSC-derived resistance to foro

92 Our study provides a biochemical mechanism for MT-dependent MT amplification

93 Results of this study identify a novel biochemical mechanism for regulation of sMLA-induced gen

94 Beyond the recognition of an alternative biochemical mechanism for the biosynthesis of cyclic ter

95 The molecular/biochemical mechanism for the differentiation suppressiv

96 These findings suggest a biochemical mechanism for the faulty cytokine balance se

97 ABPalpha and Gfi-1, and these data provide a biochemical mechanism for the generation of stable IL-7R

98 he cell-cycle machinery, thereby providing a biochemical mechanism for the genetic requirement for mu

99 These data provide a biochemical mechanism for the pathogenesis of this epile

100 Our data establish a biochemical mechanism for the role of Srs2 in crossover

101 Thus, our results provide a putative biochemical mechanism for the skeletal defects in human

102 The novel biochemical mechanism for these effects involves the abi

103 However, a biochemical mechanism for this effect has not been defin

104 sistance in several cell types, although the biochemical mechanism for this protection is unknown.

105 However, the biochemical mechanisms for electron transport between th

106 acteria and eukaryotes have evolved distinct biochemical mechanisms for producing tetrahymanol.

107 Thus, this study lends insights on key biochemical mechanisms for regulating KLF sites involved

108 Although biochemical mechanisms for repairing several forms of ge

109 arge panel of hTR variants revealed numerous biochemical mechanisms for telomerase loss of function,

110 hin, and meso-zeaxanthin, but the underlying biochemical mechanisms for this spatial- and species-spe

111 uted to the understanding of the genetic and biochemical mechanisms for TMAO degradation in M. silves

112 Consistent with this biochemical mechanism, genetic ablation of GATOR1 nullif

113 However, the biochemical mechanism governing DDB proteolysis and its

114 Despite its physiological importance, the biochemical mechanism governing Wnt acylation by Porcn i

115 ped family of helicases, whose structure and biochemical mechanisms have been studied in detail.

116 on stress and the presence of dehydrins, the biochemical mechanisms have remained somewhat elusive.

117 se findings indicate that FITs have a unique biochemical mechanism in mediating LD formation and impl

118 Here, we describe a biochemical mechanism in which PARI functions as an HR r

119 Antibiotics target specific biochemical mechanisms in bacteria.

120 servation and the coupling of mechanical and biochemical mechanisms in stabilizing motile cells.

121 Our study illuminates the biochemical mechanisms involved in insect immunity to xe

122 Here, we delineate the biochemical mechanisms involved in NOTCH-induced JAK3 ub

123 ts in our understanding of the molecular and biochemical mechanisms involved in quorum sensing as wel

124 e and fail to address pathophysiological and biochemical mechanisms involved with cartilage degenerat

125 s model insects to examine physiological and biochemical mechanisms involved with water balance, nutr

126 (MSC) cultures and delineate the underlying biochemical mechanisms involved.

127 man fetal brain, as well as the cellular and biochemical mechanisms involved.

128 Instead, biochemical mechanisms involving haploinsufficiency, dom

129 nt biotransformation reactions, but that the biochemical mechanism is not necessarily linked to ammon

130 ular dysfunction in the human heart, but the biochemical mechanism is poorly understood.

131 uch model involves a minimal number of known biochemical mechanisms: it basically relies on the inter

132 Biochemical mechanism leading from hyperglycemia to oxLD

133 of action of MMP-9 in cardiac tissue and the biochemical mechanisms leading to increased levels of MM

134 However, the biochemical mechanisms leading to the formation of this

135 unction in signaling pathways and downstream biochemical mechanisms leading to the PD phenotype.

136 The same thermodynamic and biochemical mechanisms linked to aging in somatic cells

137 l regulatory gene expression and providing a biochemical mechanism mediating O3-derived formation of

138 e is a major gap in our understanding of the biochemical mechanisms mediating their effects.

139 xperiments, this study demonstrates that the biochemical mechanisms modulated by two GCAPs in Ca(2+)

140 t histone methylation and acetylation as key biochemical mechanisms modulating KLF-mediated neurotran

141 gulate glucose uptake into cells, though the biochemical mechanism of action has been obscure.

142 biological and biochemical specificities and biochemical mechanism of action of EHT 1864.

143 m kinase Rad3 and the mediator Mrc1, but the biochemical mechanism of activation is not well understo

144 enzymes allowed us to shed some light on the biochemical mechanism of aglycon cell growth inhibition,

145 The chemical nature, order, and biochemical mechanism of all the oxygenative tailoring r

146 Together, our results establish a biochemical mechanism of an Argonaute-dependent sRNA bio

147 However, bioactive fractions and biochemical mechanism of anti-fibrotic properties of rhu

148 Together, these results indicate that the biochemical mechanism of arsenate respiration and reduct

149 NA and provides a testable hypothesis on the biochemical mechanism of cooperativity in protein assemb

150 In addition to providing a biochemical mechanism of EspF function, we find that Esp

151 Our data support the argument that the biochemical mechanism of Fe(III) reduction per se was no

152 ging questions in this regard relates to the biochemical mechanism of how exogenous environmental tri

153 mpartments critical for gene expression, the biochemical mechanism of how TDRD3 can affect the functi

154 We report here a biochemical mechanism of HURP regulation by Aurora A, a

155 The biochemical mechanism of MIIP in this process is associa

156 To elucidate the biochemical mechanism of miRNA processing, we developed

157 To better understand the biochemical mechanism of MYST autoacetylation and the im

158 Biochemical mechanism of NFIA function was evaluated usi

159 induced mTORC1 modulation and the underlying biochemical mechanism of NLK in mTORC1 inhibition in str

160 To gain insight into the biochemical mechanism of NTMT1, we have characterized th

161 Nevertheless, the biochemical mechanism of phy-induced PIF phosphorylation

162 orylation of PIF3 and PIF5 may represent the biochemical mechanism of primary signal transfer from ph

163 Here, we interrogate the biochemical mechanism of procaspase-3 activation on 1541

164 To characterize the biochemical mechanism of PUX1 action on AtCDC48, we have

165 tic properties of N348I RT and determine the biochemical mechanism of resistance to the NNRTI nevirap

166 Here we investigate the biochemical mechanism of RT inhibition and resistance to

167 nucleate the autophagosome membrane, but the biochemical mechanism of such nucleation activity remain

168 nhibitors results in a working model for the biochemical mechanism of Tax-induced activation.

169 plications of active site flexibility on the biochemical mechanism of TcTS.

170 ssembly pathway provides a framework for the biochemical mechanism of the checkpoint signaling and wi

171 conformation and provides insights into the biochemical mechanism of the luciferase oxidative step.

172 Here, we investigated the biochemical mechanism of the Top1-induced short deletion

173 To explore the biochemical mechanism of this effect, we examined the ef

174 chemokine receptors including CCR5, but the biochemical mechanism of this process has not been fully

175 To understand the biochemical mechanism of this stimulation, we directly v

176 show that UGTs play an integral role in the biochemical mechanism of TNT detoxification by plants.

177 To understand the underlying biochemical mechanism of various exocytotic processes me

178 Our studies reveal a previously unrecognized biochemical mechanism of Vpx-mediated SAMHD1 inhibition:

179 In this study, we investigate the biochemical mechanism of wild-type RAF (RAF(WT)) activat

180 However, the exact biochemical mechanism of YUCs has remained elusive.

181 cell culture systems, and their cellular and biochemical mechanisms of action are known.

182 and has provided valuable insights into the biochemical mechanisms of action of compounds with prove

183 nder different conditions differentiated the biochemical mechanisms of action of distinct M3 antagoni

184 The biochemical mechanisms of cell growth inhibition by ITCs

185 understanding of the underlying genetic and biochemical mechanisms of cephalosporin resistance in E.

186 h amino acid at each site lends insight into biochemical mechanisms of escape throughout the epitope,

187 into account in considering the genetic and biochemical mechanisms of frameshift mutagenesis in poly

188 Recent advances have helped understand the biochemical mechanisms of GlcNAc addition and removal an

189 The underlying biochemical mechanisms of how these mutations ablate act

190 Although substantial information about the biochemical mechanisms of intoxication exists, research

191 We investigated the biochemical mechanisms of KIC and leucine-stimulated ins

192 a valuable set of tools for delving into the biochemical mechanisms of lipid accumulation in algae an

193 features in T-cell progenitor cells, but the biochemical mechanisms of LMO2 function have not been fu

194 thus requires a deeper understanding of the biochemical mechanisms of pathogenicity.

195 phytanic content during food production and biochemical mechanisms of phytanic acid metabolism, as w

196 ations and epigenetics can help separate the biochemical mechanisms of regulation from the inheritanc

197 ls of biological analysis did not reveal the biochemical mechanisms of response to ocean acidificatio

198 Recent studies have revealed biochemical mechanisms of SAMHD1-mediated retroviral res

199 te investigations aimed at understanding the biochemical mechanisms of TAG metabolism in plants.

200 The biochemical mechanisms of these pathways have been well

201 B, which may provide future insight into the biochemical mechanisms of these systems.

202 w we describe how such approaches reveal the biochemical mechanisms of three NAPs that are believed t

203 Biochemical mechanisms of tissue repair were activated i

204 ches will set a new standard for elucidating biochemical mechanisms of UB-driven signaling systems.

205 egment assortment, and genome encapsidation, biochemical mechanisms of virion morphogenesis within in

206 s review summarizes the emerging data on the biochemical mechanisms, physiologic outcomes, and potent

207 KRAS(G12D) may activate PI3Kalpha by direct biochemical mechanisms, PI3'-lipid signaling remains rat

208 validate and complete this study, understand biochemical mechanisms promoting sepsis development, and

209 ifications, which are carried out by similar biochemical mechanisms, regulate nearly every aspect of

210 ardiovascular disease, as well as on a novel biochemical mechanism regulating clot stability and diss

211 cted locations will aid in understanding the biochemical mechanisms regulating circulative virus tran

212 Understanding the molecular and biochemical mechanisms regulating the blood-brain barrie

213 an lead to severe retinal pathology, but the biochemical mechanisms remain poorly defined.

214 om carnitine, the underpinning molecular and biochemical mechanisms remain unclear.

215 The underlying biochemical mechanisms remain unknown.

216 However, the underlying genetic and biochemical mechanisms remain unknown.

217 ve levels of induced plant defenses, precise biochemical mechanisms responsible for differing respons

218 To identify the biochemical mechanisms responsible for impaired insulin

219 for IMiD action, the complete molecular and biochemical mechanisms responsible for lenalidomide-medi

220 xylan synthesis through mutant analyses, the biochemical mechanisms responsible for synthesizing xyla

221 better characterize the underlying possible biochemical mechanisms responsible for the clinical find

222 In most cases, the biochemical mechanisms responsible for this signal speci

223 ses is necessary for characterization of the biochemical mechanism(s) for this class of enzymes.

224 n of activity patterns and investigations of biochemical mechanisms sensitive to physiological pertur

225 ne functionally accurate from the underlying biochemical mechanism standpoint.

226 Here, we review the biochemical mechanisms, structures, physiological functi

227 cribe its recombinant high level expression, biochemical mechanism, substrate preference, and regulat

228 The biochemical mechanism that coordinates filamentous actin

229 n in vitro transcription assay to identify a biochemical mechanism that explained the BRCA1 stimulato

230 these results identify a novel AKAP-mediated biochemical mechanism that increases TRPA1 sensitivity i

231 n vitro HtrA1 substrate suggests a potential biochemical mechanism that links ApoE4 regulation of AD

232 n general, and more specifically, identify a biochemical mechanism that may account for the significa

233 We also identify a biochemical mechanism that might contribute to this pola

234 phosphorylation is a ubiquitous, fundamental biochemical mechanism that regulates essential eukaryoti

235 The biochemical mechanisms that allow phytoplankton to limit

236 t phospholipid substitutions are fundamental biochemical mechanisms that allow phytoplankton to maint

237 iding important clues about the cellular and biochemical mechanisms that are active in normal and dis

238 Biochemical mechanisms that control the levels and activ

239 Biochemical mechanisms that control the levels and funct

240 tion is critical to our understanding of the biochemical mechanisms that control this critical tumor

241 nderstanding of the molecular structures and biochemical mechanisms that determine NF-kappaB dimer fo

242 However, the mechanical and biochemical mechanisms that ensure proper feedback contr

243 In contrast to the biochemical mechanisms that have been implicated in the

244 ver, little is known about the molecular and biochemical mechanisms that initiate this shift.

245 A central question is the biochemical mechanisms that make LTP and LTD persistent.

246 lated amylin polymerization on membranes and biochemical mechanisms that protect beta-cells from amyl

247 The biochemical mechanisms that regulate the process of canc

248 een circadian gene expression cycles and the biochemical mechanisms that ultimately facilitate circad

249 To elucidate the biochemical mechanisms that underlie detoxification and

250 e described as a model for understanding key biochemical mechanisms that underlie development and dif

251 d is, therefore, essential to understand the biochemical mechanisms that underlie genomic regulation.

252 ew we discuss the discrete biomechanical and biochemical mechanisms that underlie these architectural

253 cts has led to a deeper understanding of the biochemical mechanisms that underlie these processes.

254 The biochemical mechanisms through which eosinophils contrib

255 g clinical link between folate and NTDs, the biochemical mechanisms through which folic acid acts dur

256 presented for elucidating the molecular and biochemical mechanisms through which sex-steroid hormone

257 ng, indicating that RPM-1 utilizes different biochemical mechanisms to bind these molecules.

258 Microbes and plants have evolved biochemical mechanisms to communicate with each other.

259 Blood-feeding parasites have developed biochemical mechanisms to control heme intake and detoxi

260 eneration of reactive oxygen species and the biochemical mechanisms to detoxify and repair the damage

261 rate that P. chrysosporium has the necessary biochemical mechanisms to drive 6:2 FTOH biotransformati

262 which will be widely employed to explore the biochemical mechanisms to further understand the dynamic

263 ternative protein sequences that use diverse biochemical mechanisms to perform the derived function a

264 contain a functional allele; hence, similar biochemical mechanisms underlie the rejection of both "s

265 lecular Cell, Shiotani and Zou elucidate the biochemical mechanism underlying sequential ATM and ATR

266 We dissected the biochemical mechanism underlying the requirement for NAI

267 However, the biochemical mechanism underlying the transition from DSB

268 The biochemical mechanism underlying these abnormalities was

269 The results indicate that the genetic and biochemical mechanisms underlying accumulation of medica

270 To better understand the biochemical mechanisms underlying antithrombin antiangio

271 ractome of RNA modifications and reveals the biochemical mechanisms underlying m(6)A function in the

272 The basic biochemical mechanisms underlying many heritable human p

273 he lipidomic power for identification of the biochemical mechanisms underlying metabolic diseases.

274 Many of the molecular and biochemical mechanisms underlying methicillin resistance

275 However, the intrinsic biochemical mechanisms underlying morphogenesis and seco

276 timuli modulate mTORC1 signaling, the direct biochemical mechanisms underlying mTORC1 regulation rema

277 uld greatly facilitate identification of the biochemical mechanisms underlying numerous pathological

278 However, the biochemical mechanisms underlying Se methylation in micr

279 e to BMP stimulation, is well characterized, biochemical mechanisms underlying Smad dephosphorylation

280 However, little is known about the biochemical mechanisms underlying T cell stimulation or

281 e suggests that oleamide participates in the biochemical mechanisms underlying the drive to sleep, th

282 The biochemical mechanisms underlying their antitumor activi

283 However, the biochemical mechanisms underlying these double alteratio

284 The biological and biochemical mechanisms underlying these processes are no

285 Animal studies have explored the biochemical mechanisms underlying this effect.

286 animal model have prevented analysis of the biochemical mechanisms underlying this pathology.

287 d to human disease, and outline cellular and biochemical mechanisms underlying this phenomenon, incre

288 e data in our study reveal the molecular and biochemical mechanisms underpinning carnitine metabolism

289 ortance and power of the method for studying biochemical mechanisms underpinning disease states.

290 To understand the biochemical mechanisms underpinning DREAM function and r

291 nitrogen source; however, the molecular and biochemical mechanisms underpinning its growth remain un

292 The biochemical mechanisms used for dosage compensation must

293 he contribution of chromatin dynamics to the biochemical mechanisms utilized by these proteins to per

294 activate or repress promoters, although the biochemical mechanisms vary.

295 These simulations indicate that multiple biochemical mechanisms, when appropriately coupled, can

296 A novel approach for understanding the biochemical mechanism whereby RFUVA cross-linking stops

297 To identify the biochemical mechanisms whereby casein kinase1 (CK1) dete

298 GC B cells through both transcriptional and biochemical mechanisms, which collectively determine the

299 tabolic networks is governed by a variety of biochemical mechanisms, with inputs from other network n

300 n also facilitate elucidation of fundamental biochemical mechanisms within these systems.