ライフサイエンスコーパス: bioconjugation

1 icability for pH responsive surfaces and for bioconjugation.

2 st prompts use in both general synthesis and bioconjugation.

3 reporter and an activator molecule to assist bioconjugation.

4 nctional groups, which were used for surface bioconjugation.

5 cles may find many potential applications in bioconjugation.

6 for efficient synthesis of nanoparticles for bioconjugation.

7 ications ranging from polymer fabrication to bioconjugation.

8 ts its practice in certain situations, e.g., bioconjugation.

9 sm towards enabling site- and chemoselective bioconjugation.

10 as also been applied to peptide labeling and bioconjugation.

11 acrylic reagents for chemoselective cysteine bioconjugation.

12 group or carboxylic acid moiety) for further bioconjugation.

13 tegy for achieving ligation, attachment, and bioconjugation.

14 to the bay region for the purpose of further bioconjugation.

15 ules onto the gold nanoparticles followed by bioconjugation.

16 uperior to off-protein rates of many current bioconjugations.

17 isn -tags at the protein termini allow rapid bioconjugation and consequent purification through compl

18 ch second- and third-generation catalysts in bioconjugation and in cellular applications are highligh

19 e ]( *) is not significantly perturbed after bioconjugation and is available as a phototrigger of tyr

20 ediates, the methodology has been applied to bioconjugation and peptide labeling.

21 amely the thiol-ene photo-click reaction for bioconjugation and photocleavage reactions that allow fo

22 NAs can serve as tools for both non-covalent bioconjugation and structure-function nucleation.

23 BDSA and basic sites to facilitate gas-phase bioconjugation and to reduce charge sequestration and in

24 redox or fluorescent labeling, as well as in bioconjugations and modulation of interactions of DNA wi

25 em integrates yeast display, enzyme-mediated bioconjugation, and fluorescence-activated cell sorting

26 modern chemistry, including drug discovery, bioconjugation, and nanoscience.

27 e development, synthesis, scope of reaction, bioconjugation, and synthetic comparisons of four new ch

28 The development and bioconjugation applications of a novel Diels-Alder-based

29 w potential as benchtop reagents for diverse bioconjugation applications.

30 ins site-specifically using a chemoenzymatic bioconjugation approach.

31 a quartz slide was investigated with several bioconjugation approaches and an immunoassay for detecti

32 gnetic beads are embedded in the ECM through bioconjugation between the streptavidin-coated beads and

33 ant not only for expanding the repertoire of bioconjugation but also for the application of olefin me

34 of the acetylene allows the presentation of bioconjugation cargo to the enzyme for (18)F labelling.

35 rgeting probes (e.g., antibodies), multistep bioconjugation chemistries, different delivery strategie

36 Successful bioconjugation chemistry of Abs via a bifunctional polye

37 equivalent of a second thiol to give further bioconjugation, demonstrating that bromomaleimides offer

38 ed through a sonication-mediated method with bioconjugation flexibility.

39 (125)I-labeled triazoles functionalized with bioconjugation groups, fluorescent dyes, and biomolecule

40 Protein bioconjugation has been a crucial tool for studying biol

41 of robust surface attachment chemistries for bioconjugation has limited their uptake in biomedical di

42 oups suitable for derivatization and protein bioconjugation have also been developed.

43 cope and limitations of olefin metathesis in bioconjugation, however, remain unclear.

44 nitiated reaction that can achieve patterned bioconjugation in a highly chemoselective manner.

45 This strategy has been used extensively for bioconjugation in vitro and for protein-protein conjugat

46 In general, QD bioconjugation is completed within 1 day, and multiplexe

47 The potential of this novel bioconjugation is demonstrated through the preparation o

48 y concepts surrounding their preparation and bioconjugation is provided given the defining role these

49 ic methodologies and applications, including bioconjugation, labelling, surface functionalization, de

50 Here we report a simple and rapid protein bioconjugation method based on a one-step ligand exchang

51 A highly efficient protein bioconjugation method is described involving addition of

52 Bioconjugation methodologies have proven to play a centr

53 lly combining robust site-specific phosphine bioconjugation methods and a lipid-binding protein (SCP-

54 Site-selective bioconjugation methods are valuable because of their abi

55 The described microwave-assisted bioconjugation methods give an opportunity to synthesize

56 MOF mesopores, including succinimidyl ester bioconjugation moieties that allow for straightforward c

57 We demonstrate controlled in vivo bioconjugation of a targeted intracellular protein to se

58 The study provides a means of characterizing bioconjugation of AgNPs with aptamers and assessing biom

59 The effective bioconjugation of inorganic nanoparticles to the molecul

60 in the optical observation, fabrication, and bioconjugation of nanometer-sized gold or silver colloid

61 The bioconjugation of organometallic complexes with peptides

62 erein we report an umpolung strategy for the bioconjugation of selenocysteine in unprotected peptides

63 eveloped protocols for functionalization and bioconjugation of single-walled carbon nanotubes (SWNTs)

64 highlights the most exciting developments in bioconjugation of synthetic hydrogels targeted to tissue

65 We demonstrate bioconjugation of the squaraine Pdots and employ the Pdo

66 A covalent bioconjugation of these AuNCs with the desired antibody

67 Surface functionalisation and bioconjugation of these hybrid nanoparticles and nanocom

68 c anticancer vaccine 2 has been prepared via bioconjugation of unimolecular pentavalent construct 1-c

69 rms on demand with the help of sophisticated bioconjugation or radiolabeling techniques.

70 ch we observed known metabolic oxidation and bioconjugation pathways and turnover rates.

71 The broad utility of the bioconjugation platform was further corroborated by the

72 For this purpose, a reproducible bioconjugation procedure for preparing gold biohybrid na

73 osed amine groups in the initial step of the bioconjugation protocol.

74 hese new thaumatin variants are amenable for bioconjugation, providing chemical biology tools for tha

75 es provide the basis for the design of novel bioconjugation reactants or fluorogenic labeling agents.

76 rk, we report an electrochemically activated bioconjugation reaction as a mild, reagent-free strategy

77 After due optimization of such bioconjugation reaction, a molar ratio 1:3 (antibody:AuN

78 can be chemically modified using a standard bioconjugation reaction, showing mass transportation wit

79 Thus, bioconjugation reactions using DIBAC can be carried out

80 Maleimide groups are used extensively in bioconjugation reactions, but limited kinetic informatio

81 pholipids using abiotic but highly selective bioconjugation reactions.

82 useful for the detailed study of a number of bioconjugation reactions.

83 go-release strategies and organelle-specific bioconjugation reactions.

84 iable azido (18) F-arene clickable agent for bioconjugation reactions.

85 t and highly selective cysteine conjugation (bioconjugation) reactions that are rapid and robust unde

86 nthesis of isotopomeric Rhodamine dye-linked bioconjugation reagents enabled direct labeling of surfa

87 been synthesized for numerous applications, bioconjugation remains a challenge, often resulting in d

88 The bioconjugation results were confirmed by MS and Western

89 ing, amenability to quantitation, and facile bioconjugation schemes.

90 ellular delivery, and flexible chemistry for bioconjugations should generate broad applications of th

91 the area of PEGylation as the most important bioconjugation strategy are also summarized.

92 the cell penetrating peptide-photosensitiser bioconjugation strategy is a promising and versatile app

93 A novel bioconjugation strategy leading to ultrastable gold nano

94 This unprecedented bioconjugation strategy targets these under-utilized ami

95 lishes a unique chemoselective "unclickable" bioconjugation strategy to site-specifically modify prot

96 o-coupling reaction, and the utility of this bioconjugation strategy was further illustrated by gener

97 from a rotaxane synthesis tool into a useful bioconjugation technique.

98 od for rapid synthesis of the target Pcs and bioconjugation techniques for labeling of the oligonucle

99 Integrating the emerging advancements in bioconjugation techniques, DNA nanostructures can be rea

100 the exponential growth of new site-selective bioconjugation techniques, however very few methods have

101 Many common bioconjugation techniques, however, are inefficient, non

102 Three different bioconjugation techniques, reductive amination, amidatio

103 er a broad pH range and accessible to simple bioconjugation techniques, such as avidin-biotin binding

104 specific modification through tyrosine-based bioconjugation techniques, which leave the sensitive net

105 rface functionalization and develop flexible bioconjugation techniques.

106 hich rely heavily on robust and reproducible bioconjugation techniques.

107 nt of multifunctional materials via standard bioconjugation techniques.

108 With the availability of a novel bioconjugation technology it is expected that multivalen

109 Upon bioconjugation, the nanoprobes are magnetically focused

110 Their nanoparticle surfaces for versatile bioconjugation, their adaptable photophysical properties

111 As a fundamentally new approach to bioconjugation this methodology provides a blueprint tow

112 ort a strategy for chemoselective methionine bioconjugation through redox reactivity, using oxaziridi

113 We describe the effect of bioconjugation to colloidal Au nanoparticles on protein

114 d amino acids on virus capsids for uses from bioconjugation to crystal growth.

115 ult stem cells, and merging 3D printing with bioconjugation to fabricate hydrogels with anatomical ar

116 optical traps, we demonstrate how efficient bioconjugation to otherwise nonstick surfaces can benefi

117 t is beyond the scope of existing methods in bioconjugation to permit tagging of the "seemingly untag

118 concept, highlighting targeted intracellular bioconjugation to QDs, suggests that many cytoplasmic pr

119 ic carbene (NHC)-gold(I) complexes and their bioconjugation to the CCRF-CEM-leukemia-specific aptamer

120 "Click" chemistry bioconjugation using a poly(ethylene glycol) (PEG)-modif

121 Successful bioconjugation was confirmed by the use of fluorescent t

122 ology for covalent biomolecule modification (bioconjugation), we have developed a method that exploit

123 ies of PG9 and PG16 were further enhanced by bioconjugation with aplaviroc, a small-molecule inhibito

124 d to demonstrate facile applicability toward bioconjugation with biotin.

125 peptides are engineered with a Cys site for bioconjugation with maleimide-terminated chromophores, w