ライフサイエンスコーパス: biological assay

1 lied to 800 000 compounds identified 153 for biological assay.

2 he compounds will be active or inactive in a biological assay.

3 hetic L-DKP insulin was fully active in this biological assay.

4 n Drosophila using wing-vein patterning as a biological assay.

5 ules and have evaluated them in a battery of biological assays.

6 oses significant challenges for contemporary biological assays.

7 potency of five common KD mutants in various biological assays.

8 nalyses and confirmed by RT-PCR analyses and biological assays.

9 /mL at pH 7.4), was further characterized in biological assays.

10 that may translate into clinically relevant biological assays.

11 nds were selected and tested for activity in biological assays.

12 useful analytical platform for a variety of biological assays.

13 by time-consuming microscopic, chemical, and biological assays.

14 fect HDAC1 activity in a number of surrogate biological assays.

15 FTIs and their potencies in biochemical and biological assays.

16 oach combining label-free visualization with biological assays.

17 little effect on tyrosine phosphorylation or biological assays.

18 nd the yield was determined via chemical and biological assays.

19 studies were confirmed later by traditional biological assays.

20 (e.g., p21) by using conventional molecular-biological assays.

21 icles (PRPs) as optical reporters in typical biological assays.

22 diagnostics, high-throughput screening, and biological assays.

23 zes the activity of TGF-beta in two separate biological assays.

24 unting for the behavior of these proteins in biological assays.

25 e effect of each mutation in biochemical and biological assays.

26 d time, offering advantages over traditional biological assays.

27 method in comparison to classical molecular biological assays.

28 ing of biological reagents for surface-based biological assays.

29 lity of this photocaging strategy to execute biological assays.

30 the functionality of parental antibodies in biological assays.

31 olumes is an essential process step for most biological assays.

32 nthesis, which was subsequently confirmed by biological assays.

33 g a variety of immunological, proteomic, and biological assays.

34 photometry for readout of fluorescence-based biological assays.

35 aling in multiple cell-based biochemical and biological assays.

36 a solvent for in vivo administration and in biological assays.

37 this with biochemical measurements and cell biological assays.

38 and prolonged duration of action in in vitro biological assays.

39 n antigen mimics, as we have demonstrated by biological assays.

40 inting or patterning, chemical reactions and biological assays.

41 s easy coupling with conventional downstream biological assays.

42 activities compared with 6-DHSG in multiple biological assays.

43 f a chemical library, followed by cell-based biological assays.

44 by flow cytometry analysis and in vitro cell biological assays.

45 plex functional surfaces for high throughput biological assays.

46 try (CCMS) and were confirmed by independent biological assays.

47 Products were desilylated for biological assays.

48 ling, computation-based virtual screens, and biological assays.

49 a and thus is applicable to a wider range of biological assays.

50 erpreting the effects of PPIase mutations in biological assays.

51 ined almost complete activity in preliminary biological assays.

52 at may be useful for fluorescence-based cell biological assays.

53 ened for binding in a series of 26 different biological assays; 7-IBVM (14) exhibited affinity only f

54 o identify compounds that may interfere with biological assays, allowing their removal from screening

55 A biological assay analyzing beta-lactamase activity of C.

56 lectron donor was confirmed by both the disk biological assay and by reversed-phase HPLC analysis of

57 out using neutralizing Abs to these IFNs in biological assays and by quantitative RT-PCR.

58 ges compared with traditional biochemical or biological assays and can impact the new way of high-thr

59 ination of polymer and analytical chemistry, biological assays and computational modelling has been u

60 rganic compounds represent prerequisites for biological assays and for respective applications as pha

61 enerate visible light and is widely used for biological assays and imaging.

62 Biological assays and mutagenesis indicate that the C-te

63 ted here can be generalized to other sets of biological assays and other chemical descriptors.

64 atile sensing strategy required in practical biological assays and potentially in vivo analysis.

65 evice and method may facilitate quantitative biological assays and spur the development of the next g

66 for EGF receptor binding, and recognition in biological assays and Western blots by two HB-EGF antise

67 Enzyme-linked immunosorbent assay (ELISA), biological assay, and flow cytometry studies confirmed t

68 ed nicotinamide riboside was detected with a biological assay, and intracellular levels of nicotinami

69 he isolation of the authentic e-antigen, its biological assay, and its stabilization as an immune com

70 testing theory, operating characteristics of biological assays, and a model of viral dynamics during

71 s including surface-enhanced spectroscopies, biological assays, and chemical separations.

72 environments for cells, immune barriers, new biological assays, and self-assembly of ordered thick me

73 s based on calibration models common to most biological assays, and the resulting chip-specific param

74 ompound-buffer solutions used in the various biological assays are quantitated by LC/UV/CLND to deter

75 predict their biological activity, for which biological assays are required.

76 M(1) methyl glycoside has been submitted for biological assays as potential ligands for bacterial and

77 We employed biophysical and biological assays, as well as x-ray crystallography to s

78 ement in the detection of dopamine levels in biological assays at low femtomolar concentrations.

79 s approach, we demonstrate a high-throughput biological assay based on fluorescence resonance energy

80 Using a biological assay based on particle infectivity, we demon

81 promising for quantification of chemical and biological assays based on adsorbate-induced ordering tr

82 inase families will be determined once those biological assays become available.

83 ds should be studied using several different biological assays before being recommended to the genera

84 Paper devices can be modified for biological assays by adding appropriate reagents to the

85 probes for the development of ultrasensitive biological assays, cell imaging, or studies of single mo

86 Using proteomic biochemical and cell biological assays combined with time-lapse imaging in li

87 In biological assays conducted in an AP1 cell line expressi

88 the pyrrolotriazine-4-one series in in vitro biological assays correlated with the magnitude of the t

89 While physical and biological assays demonstrate that gpNu1DeltaK does not

90 Biological assays demonstrated a reduced proinflammatory

91 Our biological assays demonstrated for the first time that b

92 Using biological assays followed by similar in silico analysis

93 Biological assays for binding affinities and adenylate c

94 Biological assays for binding affinities and adenylate c

95 Both biological assays for enumerating functional virions wer

96 In vitro biological assays for motility, adhesion, and aggregatio

97 These 20 clones were evaluated in several biological assays for phenotypes associated with particu

98 possibility of clinical in vitro cell based biological assays for various pulmonary diseases such as

99 Multicolor optical coding for biological assays has been achieved by embedding differe

100 Biological assays have shown that ( R)-beta-amino-gamma-

101 ve inhibitors of wild-type HIV-1 protease in biological assays having Kis of 0.31-0.35 nM for 9, 0.16

102 ased parallelism of many common functions in biological assays; however, development of a practical t

103 The major modules for realizing molecular biological assays in a micro-total analysis system (muTA

104 tide microarray technology and by performing biological assays in asexual-stage Plasmodium falciparum

105 Cell biological assays in C. elegans neurons show that NRA-2

106 of advanced melanoma, there are no standard biological assays in clinical usage that can predict met

107 when carrying out genetic, genomic or other biological assays in cultured cells.

108 module, which allows a sensitive readout of biological assays in point-of-care (POC) tests, is prese

109 bstitution), with potent activity in several biological assays including tumor growth.

110 acterized by a range of biochemical and cell biological assays, including a novel high-throughput-scr

111 Signaling and biological assays incorporating ER-retained vIL-6 and hI

112 Biological assays (inflammatory mediators, oxidative str

113 e integration of information from a range of biological assays into a single conceptual framework.

114 ng expression of the genes in an independent biological assay involving mouse calvaria (skull bone) p

115 e for the isolation of any gene as long as a biological assay is available.

116 Biochemical and biological assays of 13-15 and related analogues demonst

117 ning and queries from the patent literature, biological assays of 308 selected compounds (representin

118 Traditional biological assays of phage numbers such as plaque counti

119 Circular dichroism spectra and biological assays of the analogues indicated that removi

120 Biological assays of the p16(INK4a) and p19(ARF) alleles

121 econdary and tertiary structure analyses and biological assays of the released proteins showed that e

122 Biological assays of these analogues showed that the tru

123 The biological assays of these novel structures showed cytot

124 Nevertheless, most biological assays of vascular spouting are conducted in

125 goal would be to use genetic sequence and/or biological assays of viral traits to identify those non-

126 Finally, biological assays on specific cancer cell lines showed t

127 The biological assays on the synthetic iGb3 analogues were p

128 However, expression for biological assay or at levels sufficient for recovery an

129 this indexing approach to other chemical and biological assays performed on a microfluidic chip.

130 nds from microbial sources and a reliance on biological assays rather than direct binding to monitor

131 nds from microbial sources and a reliance on biological assays, rather than direct binding, to monito

132 activity in a series of in vitro and in vivo biological assays reflective of the SERM profile.

133 ation mutagenesis--coupled to an appropriate biological assay--represents a fundamental means of achi

134 Many biological assays require the ability to isolate and pro

135 Furthermore, the biological assays reveal preferential membrane localizat

136 Biological assays reveal that both the desmethyl and C1-

137 Biological assays reveal that only Cd(II) and, to a less

138 aracterization of these iridoid analogues in biological assays revealed novel small-molecule inhibito

139 Biological assays revealed that the extract had indeed a

140 similarity in performance for a given set of biological assays should help prioritize synthesis decis

141 A protocol of two biological assays showed conclusively that inhibition oc

142 e mimetics to be selective TrkC ligands, and biological assays showed one mimetic to be an antagonist

143 Biological assays showed that Y361 was essential for the

144 nities for sophisticated and high-throughput biological assays such as cell sorting, rare cell detect

145 tion that allows implementation of different biological assays such as cell tracking or ancestry reco

146 isothermal titration calorimetry (ITC), and biological assays, such as imaging and actin binding.

147 ully extend our photothermal system to other biological assays, such as isothermal nucleic acid ampli

148 understanding of HCV biology and the lack of biological assays suitable for drug screening.

149 of measurements derived from cells and other biological assay systems treated with small molecules.

150 f robotics and automation, together with new biological assay technologies (e.g., homogeneous time re

151 lity of these measurements is dependent on a biological assay that has not been well standardized bet

152 a conformational variance was tested using a biological assay that showed that the hCG-alpha-hCG-beta

153 ptimized compound, NT-7-16, was evaluated in biological assays that confirm that it has potent activi

154 Biological assays that examine the effect of variants on

155 This system enables many types of cell biological assays that have been performed with immortal

156 In biological assays the compounds displayed anti-fungal an

157 nsor based screening method and the in vitro biological assay, the compounds 9 and 11 (propyl and ben

158 In cell biological assays, the actin cross-linking domain (ACD)

159 In biological assays, the corresponding isolated lipid A wa

160 In a panel of in vitro biological assays, the peptides act as full agonists and

161 Remarkably, in some biological assays, the simple structure is more potent t

162 e choice of displacement radioligand in each biological assay, their CoMFA StDevCoeff contour plots r

163 ves testing a large number of compounds in a biological assay to identify active compounds.

164 limited, we combined molecular modeling with biological assays to ascertain how modifications of phos

165 nts recent progress in using high-throughput biological assays to decipher aberrant pathways and netw

166 e combined biophysical characterization with biological assays to probe HD6 structure and function.

167 transmembrane domain dimerization using the biological assay TOXCAT.

168 Taken together, the results of biological assays, ultrastructural studies, and gene exp

169 SMFA is one of the few biological assays used in preclinical and early clinical

170 y and tertiary structure analyses as well as biological assays using single molecule analyses and qua

171 inhibitors in secondary in vitro and in vivo biological assays using three OvCa cell lines: HeyA8, SK

172 These biological assays usually possess high sensitivity but l

173 A biological assay was developed with corneal tissue used

174 A biological assay was performed to assess the protein val

175 With combined biochemical and biological assays we found that AME binds to the Stat3 p

176 n how stereochemistry affects performance in biological assays, we prepared a disaccharide library co

177 techniques and a well-characterized array of biological assays, we prepared original modifications to

178 Biological assays were assessed to evaluate the cytotoxi

179 determine the impact of NKA on DAR function, biological assays were conducted with NKA and DARs co-ex

180 ter than (-)-thiocolchicione (2a) in all the biological assays were three (-)-aS,7S optically pure en

181 fulness of these Al-based substrates in many biological assays where high concentration of salts are

182 The biological assays which include binding to five recombin

183 nates the diffusion limitations of a typical biological assay, which increases the sensitivity.

184 inhibit NF-kappaB driven transcription in a biological assay with a human reporter cell line; and di

185 By combining cell biological assays with cross-linking mass spectrometry,

186 Here, we employ functional biological assays with mutated TRK receptors to assess a

187 5%) so that they could be used in first-pass biological assays without further purification.