ライフサイエンスコーパス: biological clock

1 spe-26: reduced fertility; clk-1: an altered biological clock).

2 ronotype, is a manifestation of our internal biological clock.

3 development, are associated with a circadian biological clock.

4 cts, suppress melatonin, and phase-shift the biological clock.

5 eby meeting the three criteria that define a biological clock.

6 hich is important for the functionality of a biological clock.

7 eir products constitute building blocks of a biological clock.

8 scherichia coli cells expressing a synthetic biological clock.

9 re and reflect the activity of an endogenous biological clock.

10 N) of the hypothalamus function as the major biological clock.

11 iochemical ultradian drivers of the cellular biological clock.

12 and behavior are regulated by an endogenous biological clock.

13 the SCN resulting in phase resetting of the biological clock.

14 been implicated in the function of cellular biological clocks.

15 e metabolic and nutrient status to set their biological clocks?

16 We discuss how disruption of the biological clock, a consequence of modern society, can l

17 ATP, calcium, and the biological clock affect cell division and have been impl

18 Memory processes are modulated by the biological clock, although the mechanisms are unknown.

19 e that there is more than one way to build a biological clock, although there are parallels in the cy

20 ythms reflect age-related alterations in the biological clock and could be an indicator of disease.

21 e releases of neuropeptides derived from the biological clock and from a metabolic sensory organ as t

22 beta as a key factor that links autophagy to biological clock and maintains nutrient homeostasis thro

23 jacket for microECG telemetry unraveled the biological clock and normalization of QT intervals at 26

24 To investigate mechanistic links between the biological clock and pathways underlying inflammatory ar

25 the "circadian" receptors that regulate the biological clock and the pupillary reflex in mammals, is

26 ces that result in disparities between their biological clocks and how they entrain to exogenous cues

27 ights into biological problems as diverse as biological clocks and long-term memory.

28 hout life, referred to by many as the female biological clock, appears to be driven by a genetic prog

29 Most measurements on the biological clock are made at the macroscopic level of mi

30 Biological clocks are a ubiquitous ancient and adaptive

31 Biological clocks are autonomous anticipatory oscillator

32 Biological clocks are genetically encoded oscillators th

33 Biological clocks are self-sustained oscillators that ad

34 We propose that CR recruits biological clocks as a natural mechanism of metabolic op

35 Organisms have evolved endogenous biological clocks as internal timekeepers to coordinate

36 Biological clocks capture the imagination because of the

37 ental to health, deeper knowledge of how our biological clocks change with age may create valuable op

38 first to demonstrate a circadian rhythm of a biological clock component in identified neurons of a ma

39 Circadian biological clocks control many biological events, but th

40 An endogenous circadian biological clock controls the temporal aspects of life i

41 e ultradian time keepers (pacemakers) of the biological clock, COS cells were transfected with cDNAs

42 er, we found that strains with a functioning biological clock defeat clock-disrupted strains in rhyth

43 f the resetting of the multitude of internal biological clocks disrupted in a mouse model of jet lag.

44 All biological clocks entrain a set of regulatory genes to t

45 Circadian (daily) biological clocks express characteristics that are diffi

46 accumulated in these proteins to estimate a biological clock for temperate lambdoid phages.The putat

47 gland and in retinal layers associated with biological clock function provides two candidate opsinli

48 Because disruption of the biological clock has been associated with increased susc

49 Biological clocks have evolved as an adaptation to life

50 Recently, however, such biological 'clocks' have been discovered in several spec

51 the molecular machinery responsible for the biological clock in cyanobacteria and found that it exer

52 een the environmental lighting cycle and the biological clock in the suprachiasmatic nucleus (SCN) is

53 ction pathways in maintaining a synchronized biological clock in the suprachiasmatic nucleus (SCN).

54 Rhythmic behaviors are driven by endogenous biological clocks in pacemakers, which must reliably tra

55 rachiasmatic nuclei (SCN) contain the major 'biological clock' in mammals that controls most circadia

56 s to have potential for the investigation of biological clocks, including the description of internal

57 In this review we consider how sleep and biological clocks influence synaptic plasticity.

58 ion within the cell to a potential role as a biological clock, intracellular Ca is receiving a great

59 frequency, demonstrating that an endogenous biological clock is coupled to the mechanism of neurosec

60 rage intrinsic circadian period of the human biological clock is very close to 24 h.

61 at the Period3 gene, which forms part of the biological clock, is associated with altered sleep-wake

62 We first assessed if the biological clock located in suprachiasmatic nuclei (SCN)

63 An endogenous biological clock located in the hypothalamic suprachiasm

64 the endogenous human circadian pacemaker, a biological clock located in the hypothalamus.

65 es show that the molecular components of the biological clocks mediating tidal rhythms are likely dif

66 ring the machinery that underlies individual biological clocks, much less is known about how multiple

67 an visual system and indirect input from the biological clock nuclei.

68 zed for decades that mitochondria act as the biological clock of ageing, but the evidence is incomple

69 es a chronobiological mechanism by which the biological clock of morning types may be set to an earli

70 The biological clock of Neurospora crassa includes interconn

71 Thus, the biological clock of sinoatrial nodal pacemaker cells, li

72 CN) can be reset by light to synchronize the biological clock of the brain with the external environm

73 These data provide direct evidence that the biological clock of very premature primate infants is re

74 retina, absorbs blue light and triggers the "biological clock" of mammals by activating the suprachia

75 This biological clock orchestrates cellular events to occur i

76 Their "biological clock" orchestrates cellular events to occur

77 human homolog of the Caenorhabditis elegans biological clock protein CLK-2 (HCLK2), associated with

78 te an unexpected mechanism through which the biological clock regulates cholesterol homeostasis throu

79 nts strongly support the conclusion that the biological clock regulates the transcriptional activity

80 oughout torpor the suprachiasmatic nucleus ('biological clock') showed increasing activity, likely pa

81 ting the light sensitivity of the Neurospora biological clock, specifically the rapid induction by li

82 for E. gracilis, serving as an indicator of biological clock status, photosynthetic and respiratory

83 ough SCN neural networks, particularly since biological clocks such as the SCN are assumed to be temp

84 nct phases and suggests a mechanism by which biological clocks sustain high-amplitude feedback oscill

85 The biological clock synchronizes the organism with the envi

86 African-American women may have a different "biological clock" than white women, especially when unde

87 2 is a component of an output pathway of the biological clock that affects the circadian expression o

88 ctors play a crucial role in controlling the biological clock that controls circadian rhythm.

89 y homeostasis is controlled by an endogenous biological clock that is synchronized by light informati

90 Like most organisms, plants have endogenous biological clocks that coordinate internal events with t

91 Circadian rhythms are driven by endogenous biological clocks that regulate many biochemical, physio

92 d into multitissue systems which function as biological clocks that regulate the activities of the or

93 Living organisms possess biological clocks that resonate with environmental cycle

94 inant mutations in rodents with fast or slow biological clocks (that is, short or long endogenous per

95 circadian rhythms generated by the mammalian biological clock, the suprachiasmatic nucleus (SCN) of t

96 ganglion cells project predominately to our biological clock, the suprachiasmatic nucleus (SCN).

97 For biological clocks, timing, or phase, characteristics mus

98 ated profile of sensitivity of the mammalian biological clock to a melatonin signal.

99 lectric lighting has caused the near-24-hour biological clock to be set to a later time and that huma

100 sor systems that are not part of any natural biological clock to build an oscillating network, termed

101 behavior, and sets the responsiveness of the biological clock to subsequent changes in photoperiod.

102 Synchronization or entrainment of biological clocks to environmental time is adaptive and

103 warm/cold), synchronize (entrain) endogenous biological clocks to local time.

104 Most organisms use internal biological clocks to match behavioural and physiological

105 It has been proposed that the biological clock underlying the limited division potenti

106 he cellular responses of the elements of the biological clock which are induced by lighting cues to p

107 tia are associated with dysregulation of the biological clock, which contributes to disrupted circadi

108 Biological clocks with a period of approximately 24 h (c