ライフサイエンスコーパス: biological effect

1 he contribution of detected chemicals to the biological effect.

2 uptake between cells resulted in influenced biological effect.

3 ronmental concentration that has significant biological effect.

4 synergize to give a significantly heightened biological effect.

5 hat influence signaling pathways to profound biological effect.

6 ability of EGCG is a limiting factor for its biological effect.

7 ve cytoplasm where they normally exert their biological effect.

8 hotolytically released to create the desired biological effect.

9 s functionally important for miR-31-mediated biological effects.

10 nanoparticles, suggesting the involvement of biological effects.

11 termines the availability of metals to exert biological effects.

12 displays an exceedingly diverse spectrum of biological effects.

13 ion mechanism by which 3OC12 can mediate its biological effects.

14 lators of EPO and EPOR expression, and EPO's biological effects.

15 ones and should be evaluated for undesirable biological effects.

16 demonstrate that the interaction has several biological effects.

17 decreased cardiac output, and various other biological effects.

18 changes in DNA sequence can often have major biological effects.

19 r than the scientific understanding of their biological effects.

20 rs Pb and explains the absence of measurable biological effects.

21 ranberry matrix may be responsible for these biological effects.

22 stewater treatment plant (WWTP) effluents to biological effects.

23 ar organisms, in which they display profound biological effects.

24 ural abundance has hampered mapping of their biological effects.

25 nique mechanism by which these changes exert biological effects.

26 nent and therefore long-lasting economic and biological effects.

27 ould be similarly exploited to achieve other biological effects.

28 pecific chromatin regions to elicit specific biological effects.

29 rrecting for batch effects and retaining the biological effects.

30 different types of host cells have different biological effects.

31 sducers of the signals responsible for these biological effects.

32 ular pathways, but they often have divergent biological effects.

33 important step toward predicting subsequent biological effects.

34 modulator of ERK pathway activation and its biological effects.

35 ractions with binding partners and resultant biological effects.

36 C to recognize NO and transduce its multiple biological effects.

37 ructures and related physical, chemical, and biological effects.

38 y focused on socio-environmental rather than biological effects.

39 he JAK/STAT signaling pathway to exert their biological effects.

40 non-SMAD pathways to elicit a wide array of biological effects.

41 NPs to enable the separation of physical and biological effects.

42 her understanding of their stereoselectivity biological effects.

43 ors that could contribute to their differing biological effects.

44 o their molecular functions and higher level biological effects.

45 DBPs) and hence likely tend to underestimate biological effects.

46 nalysis and to evaluate potentially relevant biological effects.

47 ppropriate performance indicators, including biological effects.

48 of drug development and understanding their biological effects.

49 sment and the straightforward elucidation of biological effects.

50 ablish a structural logic that governs these biological effects.

51 e exposure may result in potentially adverse biological effects.

52 ceive high doses (>20 Gy or 100 Sv [relative biological effect = 5]).

53 y that the oligomers could elicit a systemic biological effect after dietary intake.

54 These biological effects also required both PLD activity and m

55 s into gut tissues of lugworms, causing some biological effects, although clean sand transferred larg

56 ening large chemical libraries for a desired biological effect and, conversely, ensuring biological e

57 oride metabolism is critical to identify its biological effects and avoid fluoride toxicity in humans

58 des no mechanistic relationship to potential biological effects and is inadequate as a comprehensive

59 ay have independent, but also complementary- biological effects and reinforce the need to potentially

60 However, direct biological effects and underlying neurochemical mechanis

61 is driven by multiple common variants whose biological effects are not immediately clear.

62 which preliminary clinical data of possible biological effects are obtainable, prior to undertaking

63 he tested complexes showed similar or better biological effects as compared with Auranofin, but contr

64 ore the importance of considering downstream biological effects, as tumor suppression cannot be infer

65 wever, little attention has been paid to the biological effects associated with RNA content of FBS on

66 re to (2)(1)(0)Po may have subtle, long-term biological effects because of its tropism towards reprod

67 de () is a free radical with a wide range of biological effects, but practically impossible to visual

68 s stress signaling proteins that exert their biological effect by degrading the bacterial messenger c

69 ss of chemical probes and drugs that produce biological effects by irreversibly modifying proteins.

70 Part of their biological effects can be attributed to the transfer of

71 A range of biological effects can be triggered by soil biochar that

72 ssible to quantitatively predict macroscopic biological effects caused by ion radiation on the basis

73 n bioactives, including polyphenols, however biological effects compared with non-germinated grains a

74 pression in L1-transfected cells blocked the biological effects conferred by L1 overexpression in dri

75 vegetables have been shown to have numerous biological effects consistent with chemoprotective activ

76 es, i.e., the "exposome", and their specific biological effects constitutes a new paradigm for enviro

77 ty, total proteins, drug concentrations, and biological effects (cytotoxicity and anti-migration) on

78 HNO donors show biological effects different from NO donors.

79 ter protein structure and function and exert biological effects directly by binding to free thiol gro

80 ctivates various kinases and induces various biological effects directly linked to angiogenesis in vi

81 This explains the increasing number of biological effects discovered during the past few decade

82 this silver ion release and their subsequent biological effects distinct from delivered particulate m

83 A new way to increase selectivity of biological effects entails the identification of biased

84 nt ligands are capable of inducing different biological effects, even in the same cell.

85 t downstream events likely contribute to the biological effects evoked by the peptide.

86 rtunities to prioritize chemicals, sites, or biological effects for further investigation based on co

87 y between beta-arrestin isoforms governs the biological effects for most GPCRs, as yet unexplored for

88 At the highest concentrations, however, biological effects found for the first generation were c

89 ductivity potential and fails to incorporate biological effects, geographical location, or cultivatio

90 -1), yet a ligand that would account for its biological effects has remained unknown.

91 ution, considering how their composition and biological effects have detrimental effects on cardiovas

92 er (Ag(+)) led us to claim that the observed biological effects have resulted from the AgNPs and not

93 elicitation of these cells in vivo and their biological effect in cell to cell communication during t

94 eatment strategies are having their intended biological effect in humans may facilitate development o

95 ed chemicals explained less than 0.2% of the biological effect in the PXR activation, adaptive stress

96 t phosphorylation has been reported to exert biological effects in both the mitochondrial matrix and

97 ich the same enzyme, ACSL1, confers distinct biological effects in different cell types, and these di

98 pyrrolo[2,3-b]pyridine derivatives and their biological effects in experimental models of diffuse mal

99 ocused primarily on the link between adverse biological effects in exposed test organisms on the leng

100 Sunlight has important biological effects in human skin.

101 administered in elderly individuals and has biological effects in humans that are consistent with SI

102 key regions responsible for transmitting its biological effects in lymphocytes.

103 ntestinal and oral permeability; 7) proof of biological effects in mice after oral administration.

104 We conclude that IL-21 possesses important biological effects in mononuclear phagocyte cells and th

105 d for HSPCs), and this expression results in biological effects in multi-lineage competitive repopula

106 e constituent of Cannabis sativa, exerts its biological effects in part through the G-protein-coupled

107 course of 3 weeks to link Pb distribution to biological effects in periphyton.

108 ng and cytokine secretion that elicit unique biological effects in progenitors.

109 wever, if uric acid generated by XO also had biological effects in the gastrointestinal tract.

110 y understand the response to retinoic acid's biological effects in WT HL60 cells.

111 that may be transferred to, and exert potent biological effects in, recipient cells of the circulator

112 d polyphenolic molecules that have potential biological effects including anti-oxidative, anti-inflam

113 COSAN elicits a range of cell biological effects, including altered cell morphology, i

114 ptors to mediate both unique and overlapping biological effects, including cell migration, proliferat

115 in many cancers, where it mediates important biological effects, including cell proliferation, differ

116 ue, Hassan et al. focus on the signaling and biological effects induced by stress hormones that lead

117 sive parenting of young children has lasting biological effects into adulthood.

118 changes FKBP51 for FKBP52, and the NF-kappaB biological effect is triggered.

119 sformations to enzymes and elucidating their biological effects is undoubtedly challenging.

120 ls of neointimal proliferation and sustained biological effect </=90 days compared with a polymer-fre

121 ose found for cadmium salts, suggesting that biological effects may be attributed to cadmium leaching

122 t associations (P < 0.01) between pH and the biological effects measured in R philippinarum, except f

123 hat oxidative transformation is required for biological effects mediated by covalent adduction to pro

124 Moreover, the specific biological effect of 3.1a on the glioblastoma phylogenet

125 N platform now allows for the readout of the biological effect of a toxicant through metabolomic-deri

126 Complement is involved in the biological effect of anti-beta2GPI scFv-Fc, as demonstra

127 ulation mechanism is proposed to explain the biological effect of BARF1 on M-CSF:FMS signaling.

128 uppress B cell proliferation and because the biological effect of DcR3.Fc on B cells was not blocked

129 endogenous receptor assembly, mimicking the biological effect of decoy receptors that lack the death

130 The biological effect of ETS is underlain in part by a Dnm1l

131 An enhanced understanding of the biological effect of exposure to violence is critical.

132 ecular pathway, to predict and interpret the biological effect of genetic variation that may be disco

133 Our findings suggest a biological effect of HSCT.

134 This study tested the negative biological effect of hydrocarbon deposition onto titaniu

135 25 mAb treatment sensitizes Treg cell to the biological effect of IL-7, possibly rendering more commo

136 lated data were shown to predict well a true biological effect of increasing age on white matter deve

137 Here, we show that the differential biological effect of Lys-for-Arg replacements can be und

138 We sought to compare the biological effect of paclitaxel delivered by 2 different

139 be a sensitive biomarker for assessing early biological effect of PM2.5 exposure on the developing fe

140 But the biological effect of SDT on oral squamous cell carcinoma

141 residual unmeasured confounding, although a biological effect of smoking cannot be excluded.

142 rovide more accurate insights in to the true biological effect of specific mutations.

143 We demonstrate the biological effect of sphingosine-1-phosphate contained i

144 ht to be involved in immune defense, the net biological effect of the acute phase response remains un

145 We looked for a biological effect of the tau variant by performing real-

146 However, the biological effect of this variant has not been determine

147 The biological effects of 1alpha,25-dihydroxyvitamin D3 (1,2

148 The biological effects of 3 identify it as a novel, potent m

149 imple aryl group at the turn potentiates the biological effects of a polyamide targeting the sequence

150 l biosensors allows the investigation of the biological effects of a tested sample, as well as the bi

151 heless, most of the literature describes the biological effects of acute radiation.

152 We assessed the clinical and biological effects of ACY-1215, an HDAC6-specific inhibi

153 ent for FcgammaRIIB coengagement for optimal biological effects of agonistic anti-TNFR antibodies.

154 s sensitive in the detection of clinical and biological effects of allergen immunotherapy and may be

155 s musculus whole-genome probes to assess the biological effects of an industrial settlement on inhabi

156 ession; however, the expression profiles and biological effects of Angpts on ovarian cancer remain la

157 However, data on the biological effects of anionophores are scarce, and it re

158 in/ HIF1alpha pathway may attenuate untoward biological effects of anti-angiogenic agents and tumor h

159 in/ HIF1alpha pathway may attenuate untoward biological effects of anti-angiogenic agents and tumor h

160 this EC as a tool to study the transfer and biological effects of atmospheric PAH pollution in micro

161 -of-concept study evaluated the clinical and biological effects of BI 655066 in patients with moderat

162 Debate about the biological effects of biodiesel exhaust emissions exists

163 Here, in vitro and in vivo biological effects of BPs with and without titanium sulf

164 ibitory effect of Cetn3, suggesting that the biological effects of Cetn3 are due to the inhibition of

165 The beneficial biological effects of cinnamic acid derivatives and the

166 Therefore, we interrogated the biological effects of class I HDAC inhibitors with varyi

167 Biological effects of climate change are expected to var

168 for developing and testing hypotheses about biological effects of climate change.

169 The biological effects of coactivation of AKT and N-Ras were

170 The biological effects of coffee may be substantial and are

171 associated with complex diseases might have biological effects of considerable magnitude in homozygo

172 We consider such addiction in terms of the biological effects of deprivation of metabolic substrate

173 analysis of our current understanding of the biological effects of different elements of the storage

174 was used to generate images identifying the biological effects of different treatments using ultraso

175 and sensitive screening assays to assess the biological effects of emerging contaminants.

176 Although biological effects of endocrine disrupting chemicals (ED

177 The biological effects of FGF15/19 make it an attractive tar

178 type will be an important determinant of the biological effects of FGFR inhibitors in patients.

179 rait-based approaches to quantify uptake and biological effects of fluoxetine, a selective serotonin

180 gh understanding of the photoinduced adverse biological effects of functionalized fullerenes and thei

181 Biological effects of GLI mutations were tested in lucif

182 nt in guarana can contribute to the possible biological effects of guarana powder.

183 both an H2S source and sink, and many of the biological effects of H2S relate to its interactions wit

184 ve experience importantly regulates the cell biological effects of HDACi administration, however, has

185 vide a greater understanding of the vascular biological effects of HDL, with potential therapeutic im

186 The difference in the biological effects of high-energy charged particles comp

187 The biological effects of histamine are mediated by four his

188 or) as a target gene that is relevant to the biological effects of HoxA10.

189 In the current study, we investigate the biological effects of ID331 Triticum monococcum gliadin-

190 a gain-of-function mutant that enhanced the biological effects of IFN-alpha.

191 The biological effects of IL-1beta are mediated through IL-1

192 ight into pathogenetic pathways and into the biological effects of immunomodulatory agents will help

193 lytic processing that may provide a range of biological effects of importance in wound healing.

194 sease pathogenesis, we investigated the cell biological effects of increased TMEM106B expression.

195 screens and provide initial insight into the biological effects of insertions on candidate cancer gen

196 Careful specification of biological effects of interest is very important to fact

197 ims." The risk factors are acquired from the Biological Effects of Ionizing Radiation (BEIR) VII repo

198 The indirect biological effects of ionizing radiation (IR) are though

199 lculated using the approach described in the Biological Effects of Ionizing Radiation VII report.

200 eline using the approach of the Committee on Biological Effects of Ionizing Radiation VII.

201 garding their bioavailability, the potential biological effects of isoflavones and soyasaponins in in

202 This is the first study of the biological effects of LCs on pulmonary epithelia and our

203 To study the biological effects of low GSH levels, we disrupted its s

204 nvironmental exposure to (2)(1)(0)Po and the biological effects of low-dose exposure to it so that pu

205 To determine the biological effects of low-dose radiation from SPECT MPI,

206 wledge of the metabolism of lycopene and the biological effects of lycopene derivatives.

207 G-protein-coupled receptors mediate the biological effects of many hormones and neurotransmitter

208 thylcytosine conversion, indicating opposite biological effects of Mbd1 isoforms.

209 ation of p73 rescued the transcriptional and biological effects of Mdm2 loss, indicating that p73 med

210 Biological effects of microplastics on the health of biv

211 ng targets is critical for understanding the biological effects of microRNA (miRNA) expression.

212 is apparently responsible for the different biological effects of MkMPs versus PMPs on HSPCs.

213 ve target upstream of EGFR revealed that the biological effects of MND could be abrogated by pertussi

214 ll utilized for further understanding of the biological effects of nanoparticles.

215 However, the biological effects of neuronostatin on cardiac myocytes

216 and help provide a rationale for the diverse biological effects of NGF and proNGF at the molecular le

217 Many biological effects of NPs are mediated by guanylate cycl

218 terfacial interaction and help to understand biological effects of NPs.

219 r knowledge, this is the first report on the biological effects of omega-3-derived SPMs on the humora

220 butyric acidergic forebrain neurons to major biological effects of opiates, and also challenge the ca

221 Hopefully, they will also ameliorate the biological effects of poor parenting.

222 allow full STAT5 recruitment and promote the biological effects of PRL signaling.

223 However, the long-term biological effects of proton irradiation in cancer initi

224 intermediates is relevant to understand the biological effects of radiation and to explain formation

225 Here we compare the biological effects of reading an electronic book on a li

226 hematopoiesis and focus particularly on the biological effects of Runx1 in the generation of hematop

227 Biological effects of S100A1 have been attributed to its

228 y, beta-catenin/TCF-LEF pathway mediated the biological effects of SATB2 in CSCs.

229 However, the biological effects of selective PLC-beta isozymes are po

230 number-dependent manner, as a trigger of the biological effects of shock wave treatment.

231 Syntheses and biological effects of siderophoric, aminoglycosidic, amp

232 However, research into the biological effects of small molecule anionophores is sti

233 The biological effects of SMIs on the Notch signaling cascad

234 lated genes were novel genes with respect to biological effects of smoking and might represent therap

235 In this Review we discuss the known biological effects of smoking on cancer cell biology and

236 Our findings provide insight into the direct biological effects of social inequality on immune functi

237 um Trial to further our understanding of the biological effects of sodium intake beyond blood pressur

238 uses on the inducers, pathways, enzymes, and biological effects of Sp1 phosphorylation.

239 Identification of the biological effects of specific somatic variants on allos

240 45) is overexpressed in cancer, although few biological effects of SPF45 are known, and few splicing

241 current understanding of the mechanistic and biological effects of spliceosomal gene mutations in MDS

242 literature are discussed in relation to the biological effects of supposedly positive or normal expe

243 Here, signals, mediators, and biological effects of terrein production were studied in

244 anding of the biodistribution, clearance and biological effects of the chemical(s) of interest.

245 develop appropriate models to elucidate the biological effects of the contributing variants.

246 To further establish the biological effects of the IFNL4 and rs1297860 variations

247 identifies derivative 27c, which mimics the biological effects of the irreversible inhibitors at com

248 Here, we measure the biological effects of the R1500P and L1706P MPD1 mutatio

249 LktC-mediated acylation is necessary for the biological effects of the toxin.

250 conditions, miRNA families can fine tune the biological effects of their regulation by having individ

251 Analysis of the biological effects of these mutations has revealed the t

252 mark for biophysical models that predict the biological effects of these particles.

253 llular peptides, which may contribute to the biological effects of this drug.

254 site for TTR production, we investigated the biological effects of TTR proteins in the vasculature an

255 Many of the biological effects of XO were due to the hydrogen peroxi

256 odeficiency virus (HIV) infection, but their biological effect on HIV susceptibility is not fully und

257 and the peptide moieties and evaluated their biological effect on the GT activity of E. coli PBP1b an

258 G-CSF has diverse biological effects on a broad range of cells and IL-10 i

259 ave become the mainstay for studying diverse biological effects on a genome wide scale.

260 often adversely affect vector titres due to biological effects on cell metabolism and/or on the vect

261 ns and the biliary epithelium and exerts its biological effects on cholangiocytes by interaction with

262 er, its involvement in advanced CTCL and its biological effects on CTCL pathogenesis have not been ex

263 aminants following growing concern for their biological effects on fish and other animals.

264 testicular development, could be linked with biological effects on metamorphosis and gonadal phenotyp

265 PbT (330 nM Pb(2+)) did not have observable biological effects on photosynthesis, respiration, extra

266 ein folding can have profound and unexpected biological effects on such diverse processes as cancer,

267 issues, the GLMM effectively quantified true biological effects on zebrafish locomotor response.

268 he link between the sensor responses and the biological effect onto the ecosystem into which the wast

269 ism and excretion (pharmacokinetics) and the biological effects (pharmacodynamics) of the chemical on

270 nd chronic THC intake produces a spectrum of biological effects ranging from transient psychotropic e

271 Ten pMHCII-based nanomedicines show similar biological effects, regardless of genetic background, pr

272 otein kinases activation in Netrin-4-induced biological effects related to vascular development.

273 ompounds, being directly responsible for the biological effects some of them present.

274 This model accurately accounts for biological effects such as nutrient uptake, respiration,

275 fic chemicals, groups of chemicals or global biological effects such as toxicity or genotoxicity.

276 The catabolic products were isolated and biological effects tested using a normal human colonic e

277 ccess to signaling receptors, and also exert biological effects that are independent of IGF binding.

278 -1) may have utility as biomarkers, or cause biological effects that are unaffected by endothelin rec

279 ch of these omega-3 fatty acids has distinct biological effects that may have variable clinical effec

280 onutrients because they have a wide range of biological effects that provide health-related propertie

281 transfection produced protein knockdown and biological effects that were significantly longer in dur

282 activation kinetics are critical for to its biological effects, they are tightly regulated.

283 MET mediates its specific biological effects through different intracellular signa

284 r of nociceptive transmission and exerts its biological effects through interactions with 2 distinct

285 ctive phospholipid that mediates most of its biological effects through LPA receptors, of which six i

286 we demonstrated that YAP likely mediates its biological effects through the modulation of Survivin ex

287 Protein kinases are thought to mediate their biological effects through their catalytic activity.

288 such as tetrahydrocannabinol, produce their biological effects through their interactions with canna

289 e and is particularly important for studying biological effects under low-dose ionizing radiation, sa

290 at hepatic mTORC2 exerts a broad spectrum of biological effects under physiological conditions.

291 ggested to be responsible for CXCL12-induced biological effects until the recent discovery of its sec

292 is small, soluble protein triggers a host of biological effects upon binding and activating CXCR1, a

293 AT2, and IRF9, IFN-I can mediate significant biological effects via ISGF3-independent pathways.

294 Polyphenols and biological effects were compared between malted-wheat (M

295 Biological effects were confirmed by measuring transcrip

296 ut not knockout animals, confirming that the biological effects were due to GPR119 agonism.

297 No biological effects were observed at 28-42 mm away from t

298 ived from celiac tissues and associated with biological effects when passively transferred from celia

299 , and the stability to degradation and their biological effects (when known) are discussed.

300 sion were sufficient to trigger the observed biological effects, which were not modified by further i