ライフサイエンスコーパス: biological function

1 f the seed set (e.g. degree distribution and biological function).

2 ins and cells is important for understanding biological function.

3 de and time scales, and are often related to biological function.

4 ges of protein conformation that impacts its biological function.

5 domain swapping and subsequent activation of biological function.

6 els are critical in designing materials with biological function.

7 ss of self-cleaving ribozymes of yet unknown biological function.

8 cribed in the literature, according to their biological function.

9 embrane-bound K-Ras dimers are important for biological function.

10 etails about the capsid with implications to biological function.

11 et molecule to exert a desired modulation of biological function.

12 context of the client's folding pathway and biological function.

13 tural features are likely to strongly impact biological function.

14 ransformed our ability to record and actuate biological function.

15 form homo-oligomeric complexes to regulate a biological function.

16 ures based on physical proximity rather than biological function.

17 is no experimental evidence to indicate its biological function.

18 s with unknown or uncertain molecular and/or biological function.

19 definition of PM domain necessary to support biological function.

20 impacts nucleic acid structures; hence their biological function.

21 ith high selectivity, which is important for biological function.

22 uctures could enable new approaches to probe biological function.

23 g time evaluation were used to determine its biological function.

24 ight and finely tune dimerization to support biological function.

25 e already been analyzed with regard to their biological function.

26 MATE transporter with a defined and specific biological function.

27 nguishable profiles and may have a different biological function.

28 g in cold unfolding and impairment of normal biological function.

29 mine the importance of structural motifs for biological function.

30 the excited states that connect chemistry to biological function.

31 tating their folding and activating them for biological function.

32 modification of the protein's structure and biological function.

33 lecules, providing fundamental insights into biological function.

34 eterogeneous catalysis, electrochemistry, or biological function.

35 lights the importance of fluid elasticity in biological function.

36 ellular networks for signal transduction and biological function.

37 an indirect one, which may subserve distinct biological functions.

38 is known about their accessible chemical and biological functions.

39 tensive range of physiological processes and biological functions.

40 quitin regulates a diverse range of critical biological functions.

41 pecific cysteines and contributes to various biological functions.

42 ill delimits the achievable precision across biological functions.

43 reside in noncoding regions and have unknown biological functions.

44 suggests that the noncanonical TISs can have biological functions.

45 saturated fatty acids which regulate diverse biological functions.

46 mplex circuits that ultimately mediate basic biological functions.

47 c motifs is essential for Pck1 stability and biological functions.

48 cleic acids within organisms and alter their biological functions.

49 RNA enables us to understand and control its biological functions.

50 been implicated in the regulation of diverse biological functions.

51 ing structural diversity of viruses to their biological functions.

52 cleus where they appear required for various biological functions.

53 r UB to cellular proteins and regulate their biological functions.

54 and have been shown to have a wide range of biological functions.

55 thropocene era in a way that maintains their biological functions.

56 s are useful tools to dissect their distinct biological functions.

57 ype I (PPI) helices, as tools for modulating biological functions.

58 ed transcripts and identify their underlying biological functions.

59 ntaining the coded information with multiple biological functions.

60 ion of the noncanonical inflammasome and its biological functions.

61 on and the initialization of photoresponsive biological functions.

62 l how genes work together to carry out their biological functions.

63 ophosphate bonds and involved in a number of biological functions.

64 are IL-6 family members with a wide range of biological functions.

65 , protein-protein interactions, and specific biological functions.

66 d RNAi pathways in the regulation of diverse biological functions.

67 nsive understanding of a number of important biological functions.

68 tally important, complex, and highly evolved biological functions.

69 light energy into conformational changes for biological functions.

70 anization, modes of enzymatic catalysis, and biological functions.

71 to specific carbohydrates to perform certain biological functions.

72 es of homomers are associated with different biological functions.

73 ssays play an important role in the study of biological functions.

74 ions required for heme binding and for other biological functions.

75 ficantly mutated genes with highly plausible biological functions.

76 ch genes work together to carry out specific biological functions.

77 ands, ephrins (EFNs), have vital and diverse biological functions.

78 x fluids, whose properties are linked to key biological functions.

79 ental rhythms as well as temporally organize biological functions.

80 coconjugates are widely involved in numerous biological functions.

81 tion), and they have been implicated in many biological functions.

82 ulation to downstream effector molecules and biological functions.

83 leptin (LEP) in the regulation of human APC biological functions.

84 to specific 3D structures to carry out their biological functions.

85 deglycosylation activates them to carry out biological functions.

86 les and protein modifications with disparate biological functions.

87 of membrane proteins, only a few have known biological functions.

88 used on specific NRs and their wide range of biological functions.

89 SP conformation that may ultimately lead to biological functions.

90 of the viral community and also the pivotal biological functions affiliated with microbes in the nat

91 However, pseudo-enzymes still have biological function albeit non-enzymatic like serving as

92 Because of this important biological function, aminoacyl-tRNA synthetases have bee

93 the spliced sequences for further downstream biological function analysis.

94 her genetic variants in ceRNA can affect its biological function and disease development is still an

95 he current study was designed to explore the biological function and epigenetic regulation of miR-34a

96 This study provides structural insights into biological function and facilitates future structure-bas

97 lity of folded proteins is critical to their biological function and for the efficacy of protein ther

98 ondensates to both facilitate and respond to biological function and how their metastability may unde

99 ized SNPs in IFITM3 on the basis of putative biological function and identified rs34481144 in the 5'

100 However, their biological function and impact on miRNA networks are unc

101 We determined biological function and mechanism of action of this FZD4

102 Our findings indicate that the biological function and morphology of exosomes secreted

103 Biological function and network analysis of vegetally en

104 We sought to investigate biological function and protein structure of the myxoid

105 RNase A) to the cells without a loss in its biological function and structural integrity, resulting

106 o withstand forces arising from their normal biological function and that are often disulfide bonded.

107 of epidemiological SNP biomarkers and their biological function and will enable us to develop novel

108 Despite their important biological functions and abundance, less than 2% of all

109 ns of life where they perform a multitude of biological functions and adopt a diversity of chemical s

110 They play crucial biological functions and are implicated in neurological

111 th as a medical trace element with essential biological functions and as a potentially toxic environm

112 contributing to sexual dimorphisms in normal biological functions and disease processes in affected i

113 us, they can play a critical role in various biological functions and disease processes including can

114 ell surfaces and proteins; they have various biological functions and have been implicated in health

115 Sia and polySia mediate diverse biological functions and have great potential for therap

116 eils the gene networks associated with their biological functions and how these are disrupted in comm

117 Given their key biological functions and implications in human diseases,

118 roteins that have important roles in diverse biological functions and in genetic mutations.

119 biophysical properties, that drive distinct biological functions and pathologies among self-templati

120 essed genes revealed distinct differences in biological functions and pathways before and after onset

121 ons are of fundamental importance to various biological functions and processes.

122 cture (HOS) is a crucial determinant for the biological functions and quality attributes of protein t

123 for exploring molecular probes to elucidate biological functions and the therapeutic relevance of Br

124 elated investigations of surface morphology, biological function, and chemical composition of Arabido

125 s are one of the main indicators of impaired biological function, and hence, the ability to identify

126 a proxy methodology to predict nanoparticle biological function, and therefore cellular receptor eng

127 N-glycans fulfill multiple structural and biological functions, and are crucial for productive fol

128 teins within a complex, proteins with shared biological functions, and proteins disrupted across netw

129 al cathepsins regulate an exquisite range of biological functions, and their deregulation is associat

130 IDPs play important roles in a range of biological functions, and their dysregulation is central

131 Many biological functions are carried out by protein complexe

132 Whether and how the LTR lncRNAs serve biological functions are largely unknown.

133 ions, and identify additional patterns whose biological functions are not yet characterized.

134 The aberrant alterations of biological functions are well known in tumorigenesis and

135 is essential to mapping proteoforms to their biological functions as well as discovering novel proteo

136 eal development are involved in a variety of biological functions as, epidermal differentiation, intr

137 window showed enrichment among diseases and biological functions associated with cell survival and o

138 ving intricate, though not fully elucidated, biological functions at concentration regimes far lower

139 ential cellular processes, and the number of biological functions attributed to them continues to gro

140 This module was linked to the biological functions autophagy, phagosome maturation, an

141 er protein folding is essential not only for biological function but also for secretion itself.

142 nsembles of structured RNA's are crucial for biological function, but they remain difficult to elucid

143 ells can be used to modulate and study these biological functions by means of inducing functional pro

144 a growing interest in the photoregulation of biological functions, due to the high level of spatiotem

145 ain and lose mRNAs with related and emergent biological functions during evolution.

146 Our findings identify an unknown biological function for LCE3 proteins and suggest a role

147 Our work unveils a new biological function for uPA-uPAR as mediator of a neuron

148 vation and highlighted unexpected additional biological functions for this ancient system, for exampl

149 also discuss challenges faced in identifying biological functions for this large and complex class of

150 However, other biological functions for trout pIgR or trout secretory c

151 tin's physiological ligand and, accordingly, biological function has proven experimentally difficult.

152 oderm GRN, for which both circuit design and biological function have been described, we evaluate by

153 dependent biofilm formation, but no specific biological functions have been ascribed to any of the in

154 decipher questions in diverse realms such as biological function, human diseases, evolution, ecosyste

155 diating allocation of resources to competing biological functions (i.e., hormonal pleiotropy) [1].

156 mplementary strand 11 epitope retained their biological function in Arabidopsis and tomato (Solanum l

157 ant posttranslational modifications modulate biological function in eukaryotic cells.

158 rand break repair polymerase that impact its biological function in genome maintenance.DNA polymerase

159 hydrogels are often designed with a specific biological function in mind, requiring the chemical inco

160 The clinical relevance of PPARalpha and its biological function in pancreatic cancer radiosensitivit

161 nding flux models, can be used to understand biological function in physiological contexts.

162 hown to interact with multiple proteins, its biological function in the brain remains unclear.

163 d as an intestinal stem-cell marker, but its biological function in the intestine remains to be deter

164 elationship between structure, dynamics, and biological function in virus particles and other large p

165 amily members correlated with their proposed biological functions in base excision repair and nonhomo

166 nner membrane, could have potentially useful biological functions in Gram negative bacteria.

167 essed in the liver and has a wide variety of biological functions in innate and adaptive immunity tha

168 Several other volatiles having biological functions in other organisms, as well as nume

169 e with gene expression, their biogenesis and biological functions in plants remain poorly understood.

170 among many different SNPs that share similar biological functions in response to environmental and ec

171 activities can have unique, non-overlapping biological functions in the cell.

172 tin-binding proteins responsible for diverse biological functions in the context of regulating actin

173 h is used to find over- or under-represented biological functions in the data.

174 cell-cell interactions that regulate several biological functions in the extravascular tissue.

175 s not previously connected to EGFR and whose biological functions in tumorigenesis are not well under

176 d in internal loops and associated with many biological functions including translation, regulation a

177 cadian rhythms necessary to maintain optimal biological function, including the endocrine and immune

178 disassembled into peptides with an array of biological functions, including antimicrobial, angiotens

179 perfamily and has been implicated in various biological functions, including cancer cachexia, renal a

180 ue types and mediate an astonishing array of biological functions, including platelet aggregation, sm

181 cells use the endocytic pathway for key cell biological functions, including receptor turnover and ma

182 These loci highlight novel biological functions, including response to oxidative st

183 to-cell adhesion molecule implicated in many biological functions, including tissue morphogenesis and

184 anifested an in-depth understanding of their biological functions, intact membrane-bound bitopic prot

185 nderstanding of how EPS structure relates to biological function is lacking.

186 der proteins and how this is linked to their biological function is largely unknown.

187 Furthermore, we found that SOBER1's biological function is not restricted to Arabidopsis tha

188 human genome, but direct evidence for their biological function is scarce.

189 The interplay of polymeric properties with biological function is seldom discussed.

190 e PsbS protein has not been detected and its biological function is unknown.

191 ominant sex hormones that regulates multiple biological functions, is involved in symptoms of TMDs re

192 As lipids are assigned a plethora of biological functions, it is evident that dysregulated li

193 proteins to recognize DNA and achieve their biological functions, it is important to analyze structu

194 teins were involved in a number of different biological functions, metabolic pathways and pathophysio

195 tically active APOBEC proteins execute their biological functions mostly through deaminating cytosine

196 Here, we report new data on the biological function of a CML-interacting partner, PRR2 (

197 tes the catalytic activity and consequently, biological function of A3B remains relatively unknown.

198 Here, we investigate the elusive biological function of Bcl7a and Bcl7b, two newly identi

199 atoxins C3a and C5a, the binding partner and biological function of C4a have remained elusive.

200 nth anniversary of the identification of the biological function of CRISPR-Cas as adaptive immune sys

201 d such a tool is vital for investigating the biological function of essential genes in archaea.

202 To determine the biological function of FDXR, we generated a Fdxr-deficie

203 e editing technologies for understanding the biological function of genes, and the pathological signi

204 eutrophil elastase to be a key enzyme in the biological function of IL-36Ra and that neutrophils can

205 dy aimed to elucidate potential clinical and biological function of IL-6R mRNA expression in ovarian

206 ze methylated CpG (mCpG), here we report the biological function of mCpG-dependent gene regulation by

207 Our findings reveal a novel biological function of mTORC2 in the regulation of lipog

208 ur study reveals the molecular mechanism and biological function of OGT-dependent O-GlcNAcylation in

209 cyclobutane rings as well as their perceived biological function of organism protection.

210 The biological function of Pf1 remains largely elusive.

211 The biological function of protein assemblies has been conve

212 que mycomembrane has been proposed, the true biological function of Rv3802 remains uncertain.

213 ink between SOX9 and oncogenic Kras, studied biological function of SOX9, and identified SOX9-related

214 The biological function of sterol glucosides (SGs), the most

215 e locomotion capacity and platelet-mimicking biological function of the biomimetic nanomotors offer e

216 ation and extracellular (ex-) space, but the biological function of the ex-RNA is poorly understood.

217 Biological function of the plant-produced hOPN was also

218 These structures provide key details on the biological function of the type I viral fusion machine f

219 Furthermore, the exact biological function of these binding sites was confirmed

220 -shock proteins, but their connection to the biological function of these chaperones has remained unc

221 g of benenodin-1 may also be relevant to the biological function of these molecules.

222 enomes encode dynamin-like proteins, but the biological function of these proteins has remained large

223 However, the biological function of this golgin in skin is unknown.

224 However, the biological function of this protein remains unknown.

225 Based on our analyses, we propose that the biological function of thousands of uncharacterized lncR

226 We propose that an important biological function of widespread MAE might be the gener

227 Many biological functions of ABA in mammals are mediated by i

228 Furthermore, the biological functions of active DNA demethylation in vari

229 in mantle cell lymphoma (MCL); however, the biological functions of BACH2 and its regulation of B-ce

230 e whether iPSC-derived EVs can influence the biological functions of cardiac cells in vitro and to co

231 They have been shown to inhibit biological functions of cognate target proteins, and the

232 s offers a novel approach to investigate the biological functions of CS.

233 The biological functions of DEPs included roles in photosynt

234 gether, these observations shed light on the biological functions of disulfide linkages for in vivo D

235 provides a general framework to dissect the biological functions of DNA methylation readers and effe

236 arch over the past decade has focused on the biological functions of DNA topoisomerases, and several

237 rgets of EPHX2 were assessed to evaluate the biological functions of EPHX2 and their role in AN.

238 nd scalable assays to assess known and novel biological functions of genes.

239 teins plays a crucial role in modulating the biological functions of glycoproteins.

240 The biological functions of high-density lipoproteins (HDLs)

241 odifications (PTMs) allot versatility to the biological functions of highly conserved proteins.

242 impact of methionine (Met) oxidation on the biological functions of IgG1 antibodies.

243 offers a unique opportunity for testing the biological functions of ILC2s.

244 eral, which may reflect the evolution of the biological functions of MBF1s.

245 DPs is a rapidly growing area as the crucial biological functions of more of these proteins are uncov

246 that homo-trimerization is essential for the biological functions of Myrf N-terminal fragment, and th

247 The RBCNPs retain the complex biological functions of natural cell membranes while exh

248 Elucidating these pathways should reveal new biological functions of noncoding RNA.

249 Ventura explores the biological functions of noncoding RNAs in cancer and dev

250 l-oxo species, are the basis for the various biological functions of O2-utilizing metalloproteins.

251 A interaction could provide insight into the biological functions of PC4, which remain incompletely u

252 Many of the biological functions of phenazines, such as mediating si

253 Biological functions of RNA molecules are dependent upon

254 The biological functions of SPN and SLO have been extensivel

255 mATG8s and will be valuable in decoding the biological functions of the individual LC3/GABARAPs.

256 Opto-Dab1 may be useful to study the biological functions of the Reelin-Dab1 signaling pathwa

257 One of the major biological functions of the retinal pigmented epithelium

258 a decade, the DNA-binding activities and the biological functions of these proteins have been largely

259 We further infer the biological functions of those non-coding associated gene

260 To differentiate the biological functions of Uba1 and Uba6, we applied an ort

261 n of material surfaces that elicit specified biological functions once placed in the body.

262 d solely on the catalytic role of enzymes in biological function, overlooking the potentially critica

263 The remarkable plasticity and plethora of biological functions performed by macrophages have entic

264 gram of approximately 100 genes with diverse biological functions, regardless of cell type or cellula

265 her with the transcriptional module indicate biological functions related to seedling establishment.

266 vacuolar (V-type) ATP synthase fulfills its biological function remains largely fragmentary.

267 ull scale of their chemical capabilities and biological functions remains unknown.

268 Rewriting the genetic code could lead to new biological functions such as expanding protein chemistri

269 ons can yield useful insights into potential biological function, such as prediction of RNA-binding a

270 quence-dependent and enriched for particular biological functions, such as fatty acid synthesis, and

271 n mammalian cells and is involved in various biological functions, such as protein function, cancer p

272 ce in these devices they mimic most of their biological functions, such as reversible binding, cataly

273 In general, the biological functions supported by these diverse polypept

274 A critical biological function that can be compared among early mam

275 e, we will explore the current repertoire of biological functions that are associated with this essen

276 They define chromatin domains with distinct biological functions that come in sizes ranging from sin

277 KLK5 has biological functions that include degrading desmosomal p

278 products control diverse, cell type-specific biological functions that include mineral homeostasis.

279 e (IRAP) is an enzyme with several important biological functions that is known to process a large va

280 ially methylated regions show enrichment for biological functions that may affect the capacity of hat

281 Despite their important biological functions, the evolution and diversification

282 that selection is driven solely or mainly by biological function, these findings point to fine-tuned

283 revealed a mechanism that may regulate BRD4 biological function through phosphorylation, which, when

284 transcription factor, which evolved a novel biological function through well-characterized mechanism

285 uman cancer, has been known to regulate many biological functions through its non-histone substrates.

286 a crucial factor influencing a wide range of biological functions throughout all kingdoms of life.

287 Lipids are ubiquitous and serve numerous biological functions; thus lipids have been shown to hav

288 activity states, and reveals T-cell-related biological functions tied to, and possibly predicting or

289 f the same gene tend to be more divergent in biological function, tissue expression, and disease phen

290 has complicated the attribution of distinct biological functions to specific FZD and Wnt subtype int

291 research groups for their ability to predict biological functions using Gene Ontology and gene-diseas

292 10(-)(5) were prioritized according to their biological function, using RegulomeDB, haploreg, and Gen

293 of the RNA pyrophosphohydrolase RppH, whose biological function was previously assumed to be pyropho

294 plex organisms and have a critical impact on biological functions which could cause disease.

295 etabolites produced by microbes have diverse biological functions, which makes them a great potential

296 sent in all lines are enriched for essential biological functions, while genes present in only some l

297 g of how threonine phosphorylation regulates biological function will be accelerated by general metho

298 perspective the molecular mechanisms driving biological functions with the ones driving synthetic mol

299 art, illustrating the ability to incorporate biological function within the bulk material with possib

300 portance of this modification for regulating biological functions within this cellular compartment.