ライフサイエンスコーパス: biological membrane

1 the conformation of the APP-TM domain at the biological membrane.

2 brane domains, for transporter embedded in a biological membrane.

3 mediate the transfer of fatty acids across a biological membrane.

4 l species via a series of acceptors across a biological membrane.

5 disease) reside in close association with a biological membrane.

6 -association of the RET-TM was observed in a biological membrane.

7 turally occurring domains, such as rafts, in biological membranes.

8 highly conserved and essential components of biological membranes.

9 eins undergo random and passive diffusion in biological membranes.

10 ers use ATP to drive solute transport across biological membranes.

11 ilms and the role of lateral organization in biological membranes.

12 ame material determines the interaction with biological membranes.

13 t of water and small neutral solutes through biological membranes.

14 ls that translocate monovalent anions across biological membranes.

15 e to the heterogeneous and dynamic nature of biological membranes.

16 rom soluble proteins by their insertion into biological membranes.

17 stems that translocate cargo into and across biological membranes.

18 couple mechanosensitive elements in crowded biological membranes.

19 ane pores when in contact with detergents or biological membranes.

20 e of observed interactions between Abeta and biological membranes.

21 ated ion channels are excitable nanopores in biological membranes.

22 els that facilitate the flow of water across biological membranes.

23 rolling the dynamic structural properties of biological membranes.

24 phospholipids are an important component of biological membranes.

25 ng the organization and physical behavior of biological membranes.

26 noparticle assemblies, and interactions with biological membranes.

27 upon interaction with other proteins and/or biological membranes.

28 e these proteins to fuse two closely apposed biological membranes.

29 imulations cannot yet span the complexity of biological membranes.

30 d-protein interactions play pivotal roles in biological membranes.

31 inding of Cu between the dissolved phase and biological membranes.

32 protons that allow for fast diffusion along biological membranes.

33 s from static quenching FRET measurements in biological membranes.

34 investigating supramolecular interactions in biological membranes.

35 tting analysis of EX-TM-CYTO interactions in biological membranes.

36 the structural and functional properties of biological membranes.

37 d in concert with various proteins, RNA, and biological membranes.

38 mposition in the inner and outer leaflets of biological membranes.

39 mer's disease, potentially via disruption of biological membranes.

40 bilize cholesterol-dependent nanoclusters in biological membranes.

41 ions of integrin alphaIIbbeta3 TM helices in biological membranes.

42 ing proteins are predicted to be embedded in biological membranes.

43 processes, as well as their ability to mimic biological membranes.

44 es, associated proteins, and their effect on biological membranes.

45 uncommon challenges for its transport across biological membranes.

46 on about receptor-mediated processes in real biological membranes.

47 Rayleigh scattering) and high affinities for biological membranes.

48 the anticancer drug methotrexate across the biological membranes.

49 ous variety of small solute molecules across biological membranes.

50 (2) observed in artificial bilayers apply to biological membranes.

51 se fluorophores impart a strong affinity for biological membranes.

52 ngophospholipids, occurs in minor amounts in biological membranes.

53 ions against concentration gradients across biological membranes.

54 ns, small molecules or macromolecules across biological membranes.

55 that mediate substrate translocation across biological membranes.

56 f proteins in binding and transport of FA in biological membranes.

57 l parameter regulating functional aspects of biological membranes.

58 ed in terms of several established models of biological membranes.

59 y with, the activity of the same peptides in biological membranes.

60 acteria to humans, to pump substances across biological membranes.

61 ships in lipid vesicles to their activity in biological membranes.

62 /or conformations that occur in proximity to biological membranes.

63 ound effects on the fluidity and function of biological membranes.

64 ein concentration in fusion of heterogeneous biological membranes.

65 stigating models of ligand-gated channels in biological membranes.

66 ial creatine kinase and type I hexokinase on biological membranes.

67 nd hydrolysis to facilitate transport across biological membranes.

68 he mechanisms governing FFA transport across biological membranes.

69 on of larger scale dynamic rearrangements of biological membranes.

70 l the mechanism of attack translates to real biological membranes.

71 hat can quantify antibiotic transport across biological membranes.

72 as a general feature of the organization of biological membranes.

73 a passive structural role as the backbone of biological membranes.

74 h catalyze the transport of phospholipids in biological membranes.

75 id nanoparticles (liposomes) as a mimicry of biological membranes.

76 the bilayer normal that naturally occurs in biological membranes.

77 cific roles of lipid structure remodeling in biological membranes.

78 o control the transport of Cl(-) ions across biological membranes.

79 ons cause the softening or stiffening of the biological membranes.

80 pted 'universal' value (~1 microF/cm(2)) for biological membranes.

81 erve to transport a variety of anions across biological membranes.

82 ically coupled exchange of Cl- and H+ across biological membranes.

83 on the formation of oligomeric pores within biological membranes.

84 itectures, the most prominent examples being biological membranes.

85 on encountered for proteins diffusing within biological membranes.

86 olding steps or secretion across one or more biological membranes.

87 etic COSAN membranes and naturally occurring biological membranes.

88 tant principle for the spatial patterning of biological membranes.

89 However, in vivo, Rab11 recruits RCP onto biological membranes.

90 ments, especially oxidizing environments and biological membranes.

91 lateral heterogeneities in lipid systems and biological membranes.

92 is particularly appropriate for the study of biological membranes.

93 eins and the overall mechanical stability of biological membranes?

94 of FE tell us about the overall structure of biological membranes?

95 nal involvement of membrane micro-domains in biological membranes, alphaS-induced domain formation ma

96 a strong potential for self-association in a biological membrane and that this interaction occurs via

97 anostructure, which is able to cross several biological membranes and accumulate in tumor tissues by

98 ide (DDAB) was used to mimic lipid layers of biological membranes and acted as an interface between G

99 Polyunsaturated phospholipids are common in biological membranes and affect the lateral structure of

100 Supported lipid bilayers (SLBs) mimic biological membranes and are a versatile platform for a

101 constructs can serve as suitable mimetics of biological membranes and are fully soluble in aqueous en

102 roteins do not fare well when extracted from biological membranes and are unstable or lose activity i

103 ve important roles as structural entities of biological membranes and as regulators of cellular growt

104 ts into the thermodynamics and biophysics of biological membranes and binding of small molecules to m

105 liposomes, are versatile tools for modelling biological membranes and delivering foreign objects to c

106 e toxic alpha-synuclein oligomers to perturb biological membranes and disrupt cellular function; thes

107 and synthetic amphiphiles serve as mimics of biological membranes and enable the delivery of drugs, p

108 d JGDs serve as powerful tools for mimicking biological membranes and for biomedical applications suc

109 measurements of helix-helix interactions in biological membranes and genuine thermodynamic data from

110 es from proteins during translocation across biological membranes and hence play a vital role in cell

111 A(2)) enzymes become activated by binding to biological membranes and hydrolyze phospholipids to free

112 the importance of lipid species diversity in biological membranes and importantly, it suggests that m

113 ystem that mimics the mechanical behavior of biological membranes and is able to self-assemble into c

114 ade characterization of such organization in biological membranes and model systems difficult.

115 ve hydrophilic substrates across hydrophobic biological membranes and play key roles in plant nutriti

116 he nature of the interactions of alphaS with biological membranes and provide insights into their rol

117 ting their close proximity to the channel in biological membranes and supporting their functional rel

118 ayer-spanning, monovalent cation channels in biological membranes and synthetic bilayers.

119 of the lateral organization of components in biological membranes and the evolution of this arrangeme

120 ies alter subsequent interactions with model biological membranes and the Gram-negative bacterium She

121 underlying lateral heterogeneity (rafts) in biological membranes and the role of domains in the regu

122 and hybrid DSs, their similar thickness with biological membranes and their imaging by fluorescence a

123 ver, the widely observed differences between biological membranes and their in vitro counterparts are

124 e valuable models for fundamental studies of biological membranes and their interaction with biologic

125 ; however, TGs are not capable of traversing biological membranes and therefore need to be cleaved by

126 uipped to carry therapeutic molecules across biological membranes and, therefore, have been widely re

127 stinal tract, steric constraints in crossing biological membranes, and clearing by enterohepatic circ

128 Na,K-beta TMD homo-oligomerized in biological membranes, and mutation of the glycine zipper

129 rmation and membrane organization in complex biological membranes, and provide a background for unrav

130 ul new means to study molecular movements in biological membranes, and the technology is widely appli

131 Biological membranes are a crucial aspect of living syst

132 A significant fraction of lipids in biological membranes are charged.

133 Biological membranes are complex, self-organized structu

134 Biological membranes are constantly exposed to forces.

135 Biological membranes are densely packed with membrane pr

136 Because biological membranes are diverse and nonuniform, we expl

137 Biological membranes are exposed to a number of chemical

138 fects numerous biological processes and some biological membranes are exposed to extreme pH environme

139 Lipid bilayers and biological membranes are freely permeable to CO(2), and

140 Although biological membranes are involved in fibril plaque forma

141 Mechanical properties of biological membranes are known to regulate membrane prot

142 However, biological membranes are not composed solely of phosphol

143 tched surfaces provided strong evidence that biological membranes are organized as lipid bilayers wit

144 Biological membranes are organized into dynamic microdom

145 Unlike their model membrane counterparts, biological membranes are richly decorated with a heterog

146 Biological membranes are two dimensional, making the dis

147 understand the mechanism of transport in the biological membrane as a whole, the effects of the lipid

148 The curvature of biological membranes at the nanometer scale is criticall

149 l changes observed in synthetic and isolated biological membranes, BAs reorganized intact cell membra

150 ability to probe the viscoelastic effects of biological membranes, becoming a new tool for tribology

151 tion, tension regulation, and trafficking in biological membranes, but the mechanisms responsible for

152 enzymes that actively transport ions across biological membranes by interconverting between high (E1

153 imersomes (DSs), with similar thicknesses to biological membranes by simple injection from ethanol so

154 membrane-binding properties of alpha-syn to biological membranes by using bi-functional chemical cro

155 The diverse lipid environment of the biological membrane can modulate the structure and funct

156 The structure and composition of a biological membrane can severely influence the activity

157 nfirm that the global physical properties of biological membranes can act as information pathways bet

158 The structural organization of proteins in biological membranes can affect their function.

159 The electrostatic properties of biological membranes can be described by three parameter

160 Model biological membranes can be employed for systematic inve

161 In this contribution we show that biological membranes can catalyze the formation of supra

162 The simplest, single-component biological membrane challenges accepted models of macrom

163 In biological membranes, changes in lipid composition or me

164 nterest in developing synthetic analogues of biological membrane channels with high efficiency and ex

165 ry and many key transport characteristics of biological membrane channels.

166 he resulting biomimetic nanorobots possess a biological membrane coating consisting of diverse functi

167 Biological membranes composed of lipids and proteins are

168 Biological membranes consist of bilayer arrangements of

169 Biological membranes contain ion channels, which are nan

170 the transport of hydrophilic proteins across biological membranes continues to be an important undert

171 Interactions of macrolide antibiotics with biological membranes contribute to their bioavailability

172 We asked if a biological membrane could employ kinetic energy to trans

173 Biological membranes create compartments, and are usuall

174 protein scaffolding is a key feature of many biological membranes, creating gradients in nanoparticle

175 Biological membranes define not only the cell boundaries

176 bstitution, which precludes diffusion across biological membranes, e.g., blood-brain barrier.

177 rom synthetic membranes can be translated to biological membranes, enabling the formation of gel fibe

178 Curving biological membranes establishes the complex architectur

179 family, facilitate extraction of lipids from biological membranes for their loading onto CD1d molecul

180 These membranes have similar dimensions to biological membranes found in cells, and previously COSA

181 Biological membrane function, in part, depends upon the

182 Fluidity is essential for many biological membrane functions.

183 Additionally, two biological membrane fusion models-yeast cell mating and

184 dings showing membrane integrity loss during biological membrane fusion suggests new mechanistic mode

185 SNARE proteins catalyze many forms of biological membrane fusion, including Ca(2+)-triggered e

186 rcome, one which we estimate at 13 k(B)T for biological membranes, fusion involving small vesicles sh

187 Its interaction with the lipid part of biological membranes has been the subject of intensive s

188 Active transport in biological membranes has been traditionally studied usin

189 n lipid components in raftlike structures of biological membranes, has not been fully explored.

190 membrane abnormalities to various diseases, biological membranes have been acknowledged as targets f

191 For example, design features from biological membranes have been applied to break the perm

192 tner or capable of mimicking the fluidity of biological membranes have been conceived by multitopic i

193 Biological membranes have layers of varying hydrophobici

194 Biological membranes have long been thought of as elasti

195 nctional studies of lateral heterogeneity in biological membranes have underlined the importance of m

196 rovide an effective approach to characterize biological membrane heterogeneities.

197 blish and maintain phospholipid asymmetry in biological membranes; however, little is known about the

198 how this combined analysis can be applied to biological membranes, human erythrocytes were treated si

199 re it transports anticancer drugs across the biological membranes in an ATP-dependent manner.

200 aired monoacylglycerol lipase recruitment to biological membranes in post-mortem Alzheimer's tissues,

201 r mechanisms of protein translocation across biological membranes in precisely defined experimental c

202 -binding proteins that transport ions across biological membranes in response to light.

203 maximum stability and dynamic properties to biological membranes in response to nutritional or envir

204 hese bright Arch variants enable labeling of biological membranes in the far-red/infrared and exhibit

205 Furthermore, RemCA directly binds to biological membranes in vitro, shows higher affinity for

206 nal region, which suggests interactions with biological membranes in vivo.

207 likely to create cell-like hybrids from any biological membrane including human cells and thus may e

208 ter simulations are now widely used to study biological membranes, including increasingly mixed lipid

209 es, translocation of the permeant across the biological membrane is traditionally assumed to obey the

210 ination of inorganic gold nanoparticles with biological membranes is a compelling way to develop biom

211 equired for transport (ESCRT) machinery from biological membranes is a critical final step in cellula

212 The transfer of fatty acids across biological membranes is a largely uncharacterized proces

213 Gated ion transport across biological membranes is an intrinsic process regulated b

214 Signal transduction across biological membranes is central to life.

215 The lipid bilayer typical of hydrated biological membranes is characterized by a liquid-crysta

216 The curvature of biological membranes is controlled by membrane-bound pro

217 hich lipids regulate protein function within biological membranes is critical for understanding the m

218 Fine-tuning of the biophysical properties of biological membranes is essential for adaptation of cell

219 proteins and the lipid-bilayer component of biological membranes is expected to mutually influence t

220 The scission of biological membranes is facilitated by a variety of prot

221 Nitrate and nitrite transport across biological membranes is often facilitated by protein tra

222 on of light energy into ion gradients across biological membranes is one of the most fundamental reac

223 h artificial membranes, the interaction with biological membranes is rapidly reversible and is not dr

224 mbrane, revealing that the hydrophobicity of biological membranes is significantly higher than apprec

225 The fluid mosaic model of biological membranes is that of a two-dimensional lipid

226 The lateral organization of biological membranes is thought to take place on the nan

227 Proton diffusion along biological membranes is vitally important for cellular e

228 tes and participates in ion transport across biological membranes, is involved in genetic incompatibi

229 arnessing nanoscale mechanical energy within biological membranes, it is possible to promote controll

230 mining variable in confined systems, and, in biological membranes, it may provide a means to regulate

231 The fusion of sealed biological membranes joins their enclosed aqueous compar

232 Many S. aureus toxins damage biological membranes, leading to cell death.

233 in-induced lipid exchange is used to prepare biological membrane-like asymmetric small unilamellar ve

234 scinating yet poorly studied molecules among biological membrane lipids.

235 In biological membranes, many factors such as cytoskeleton,

236 cal requirement for charge to balance across biological membranes means that the transmembrane transp

237 As a biological membrane model, lipid monolayers at the gas-l

238 reflect lipid-phase separation events in the biological membrane of the GJ plaque, leading to increas

239 approach toward more complex systems such as biological membranes or energy conversion devices, adapt

240 hways are summarized briefly, and studies of biological membrane organization are described in greate

241 rs bound in a phospholipid bilayer akin to a biological membrane phase.

242 Biological membranes play an essential role in living or

243 Phase separation in biological membranes plays an important role in protein

244 Biological membranes present a highly fluid environment,

245 However, the mechanisms of transport across biological membranes remain unclear.

246 diffusion of cholesterol is fast relative to biological membrane remodeling.

247 pore formation in planar lipid bilayers and biological membranes, resulting in an inability to intox

248 Biological membranes segregate into specialized function

249 e investigated in situ the ultrastructure of biological membranes, selected from several cell types f

250 s well as the understanding of mechanisms of biological membrane shaping.

251 nt electrostatic interactions, colloidal and biological membranes share many of the same physical sym

252 the cell-penetrating-peptide (CPP) type on a biological membrane, single fluorescently labeled oligoa

253 Organization in biological membranes spans many orders of magnitude in l

254 in mammalian lipids have profound effects on biological membrane structure, dynamics and lipid second

255 In the Fluid Mosaic Model for biological membrane structure, proposed by Singer and Ni

256 nds, including those that may be embedded in biological membranes such as aT.

257 rfacial stability of such diverse systems as biological membranes such as lung surfactant and nanopar

258 s affect the composition and organization of biological membranes, suggesting a potential mechanism f

259 ers associated in distinct ways with various biological membranes, suggesting that a detailed investi

260 The biological membrane surrounding fat globules in milk (th

261 eir interaction strengths were measured in a biological membrane system.

262 terogeneous spatial-temporal organization of biological membrane systems.

263 rated that significant local deformations of biological membranes take place due to the fields of cha

264 ovide a better model for the organization of biological membranes than lipid mixtures with microscale

265 tions between receptor EX-TM-CYTO domains in biological membranes that are important in regulation of

266 In biological membranes the alignment of embedded proteins

267 In systems mimicking biological membranes, the CD3 chain localization is modu

268 e these are less than perfect mimics of true biological membranes, the structures are often confirmed

269 e membranes in fuel cells to ion channels in biological membranes, the well-specified control of ioni

270 of rhodopsin activation incurred by the non-biological membranes: the cationic membrane drives a tra

271 he ability to efficiently translocate across biological membranes through still poorly-characterized

272 How a nonenveloped virus transports across a biological membrane to cause infection remains mysteriou

273 n CA activity suggests that the tightness of biological membranes to CO(2) may uniquely be regulated

274 rstanding how alpha-synuclein interacts with biological membranes to promote neurological disease mig

275 Numerous bacterial toxins can cross biological membranes to reach the cytosol of mammalian c

276 study unveils a novel design concept of non-biological membranes to reconstitute and harness GPCR fu

277 Polar lipids must flip-flop rapidly across biological membranes to sustain cellular life [1, 2], bu

278 tors that couple proton translocation across biological membranes to the synthesis/hydrolysis of ATP.

279 receptor) proteins mediate fusion by pulling biological membranes together via a zippering mechanism.

280 Proton transfer across biological membranes underpins central processes in biol

281 s are pumps that transport substrates across biological membranes using the energy of ATP hydrolysis.

282 In biological membranes, various protein secretion devices

283 The fluid mosaic model for biological membranes was formulated 40 years ago.

284 ultiwalled carbon nanotubes (MWNTs) on model biological membranes was investigated using a quartz cry

285 ely charged lipids, similar to that found in biological membranes, was sufficient to drive alpha-synu

286 interactions affected domain organization in biological membranes, we assayed the effects of BAs on b

287 To mimic charged biological membranes, we studied phase separation and do

288 Asymmetric vesicles that mimic biological membranes were prepared with sphingomyelin (S

289 passively modulating the local properties of biological membranes, when in contact with a support suc

290 Membrane proteins are embedded in the biological membrane where the chemically diverse lipid e

291 tegrates indiscriminately into virtually any biological membrane, where it forms sevenfold pyramids.

292 d monolayers of defined composition to mimic biological membranes, which were probed by x-ray reflect

293 de mimics of double-bilayer and multibilayer biological membranes with dimensions and number of bilay

294 DS) micelles, which may be a better model of biological membranes with phospholipids that have anioni

295 dacy of glycodendrimersomes as new mimics of biological membranes with programmable glycan ligand pre

296 volves the interaction of these species with biological membranes, with a subsequent loss of integrit

297 measure the association of drugs to a single biological membrane without chemical modification.

298 ble to deliver its catalytic domain across a biological membrane without the need for any eukaryotic

299 adily soluble in aqueous buffer, yet crosses biological membranes without cellular assistance: an une

300 phospholipid constituents of virtually every biological membrane yet they play fundamental roles in c