ライフサイエンスコーパス: biologically

1 a heterogeneous disease both clinically and biologically.

2 This likely prevents formation of biologically aberrant multi-layered capsids in the virio

3 This results in a more biologically accurate model of the evolution of learning

4 Studies on the photocontrol of biologically active agents mostly rely on UV light, whic

5 aggressors notably through the production of biologically active alkaloids.

6 In the majority of cases, the content of biologically active all trans vitamin K2MK-7 was below i

7 ctors to synthesize drugs, agrochemicals and biologically active and advanced materials.

8 ssing T. gondii's GRA15 and ROP16 kinase are biologically active and induced immunological phenotypes

9 iller yeasts, K28 is structurally stable and biologically active as a disulfide-bonded heterodimer, w

10 of other cell wall polymers may be similarly biologically active as elicitors and may help to reinfor

11 ABQs that contain substituent groups on the biologically active aziridine do not function as TbNTR o

12 Biofilms are likely the most abundant and biologically active biomass fraction in sewers.

13 nsive and effective means to create durable, biologically active biomaterials.

14 nt mice, GFAP-C3a transgenic mice expressing biologically active C3a in the central nervous system, a

15 have been widely applied to the synthesis of biologically active complex natural products containing

16 mines are a fundamentally important class of biologically active compounds and the ability to manipul

17 The method is based on extraction of these biologically active compounds into silicone oil, acting

18 A screening of 1,000 biologically active compounds revealed that a selective

19 n the efficient, gram-scale synthesis of key biologically active compounds targeting the cannabinoid

20 Butia contain several biologically active compounds with potential health bene

21 by the concise stereoselective syntheses of biologically active compounds, such as the antifungal in

22 re important building blocks for natural and biologically active compounds, used as spin-trap reagent

23 key structural moieties of numerous natural biologically active compounds.

24 ons are vital to access natural products and biologically active compounds.

25 hat the skin-penetrating aptamer retains its biologically active conformational structure capable of

26 d dog and allows a sustained delivery of the biologically active conjugate 1.

27 e two polymers were also used to deliver the biologically active Cre recombinase into a loxP-reporter

28 Substitution with biologically active factor H could potentially treat a v

29 Furthermore, biologically active fragments C3a and C5a, produced duri

30 pressed CCT5 chaperonin subunits, which form biologically active homooligomers, also promote the disa

31 ests show that a thioamide GLP-1 analogue is biologically active in rats, with an in vivo potency for

32 onfirmed that self-reproduced etanercept was biologically active in vitro.

33 Efficient intracellular delivery of biologically active macromolecules has been a challengin

34 ATEMENT It is well accepted that myelin is a biologically active membrane in active communication wit

35 BSTRACT: Previously we demonstrated that the biologically active metabolites of 17beta-oestradiol, 2-

36 , which are building blocks for a variety of biologically active molecules and natural products.

37 exes enables the synthesis of representative biologically active molecules and trifluoromethyl analog

38 The synthesis of complex, biologically active molecules by catalyst-controlled, se

39 which are found in many natural products and biologically active molecules, and offers a synthetic ha

40 Biologically active natriuretic peptides (NPs) are an in

41 hough a large number of reviews and books on biologically active natural products already exists, mos

42 and affinities up to 20 nM were obtained for biologically active oligopeptides in water.

43 There are many biologically active organic molecules that contain one o

44 lfide bonds are reduced to produce a linear, biologically active peptide.

45 , a multifunctional protease known to cleave biologically active peptides and aide in coronavirus ent

46 nd the reaction can be used to easily access biologically active phenethylamine derivatives.

47 en species (ROS/RNS) are assumed the central biologically active plasma components.

48 , these cells release a variety of preformed biologically active products, followed by a wave of medi

49 e strong and directional interaction between biologically active protein subunits.

50 s, in particular their capability to produce biologically active regulatory cytokines.

51 difficulty of delivering high quantities of biologically active single guide RNAs (sgRNAs).

52 Karplus and coworkers that proteins in their biologically active state should exhibit a dynamics simi

53 chniques for attaining the identities of the biologically active titanium species and how these inter

54 Unfortunately, wastewater contains biologically active, long-lived pharmaceuticals, even af

55 this apparent paradox with the discovery of biologically active, nuclear CD24 (nucCD24) and finding

56 Unfortunately, wastewater often contains biologically active, pseudopersistent pharmaceuticals, e

57 , particularly because such TPs might remain biologically active.

58 ng regulatory mechanisms, we developed three biologically anchored mathematical models: 1) parallel a

59 eculate that micromolar H2O2 is created both biologically and abiotically at natural oxic/anoxic inte

60 Varlilumab was biologically and clinically active.

61 riant, oncogenic fusions, Ewing Sarcoma is a biologically and clinically aggressive disease with a hi

62 p learning model can be trained to represent biologically and clinically meaningful abstractions of c

63 lergens and that such patterns might be more biologically and clinically relevant.

64 system has relevance to emerging classes of biologically and environmentally degradable electronic d

65 Many biologically and pharmaceutically active natural product

66 ting model circuit is thus fully constrained biologically and provides a functional interpretation fo

67 ed by greater community engagement targeting biologically and socioeconomically vulnerable groups, wo

68 istinct protein expression profiles that are biologically and therapeutically relevant.

69 Collectively, we decrypt molecularly, cell biologically, and genetically the importance of the dive

70 ression of these molecules is clinically and biologically associated with HP dependence.

71 accounts for half or more of the removal of biologically available nitrogen ("fixed N") from the oce

72 Removal of biologically available nitrogen (N) by the microbially m

73 event inhibitory MTA accumulation and retain biologically available sulfur, most organisms possess th

74 object manipulation, provides a continuous, biologically based concept for studying G as it pertains

75 tcome pathway (qAOP) consists of one or more biologically based, computational models describing key

76 rsus alternative, that is, reduced-input and biologically based-organic, management practices for a c

77 We biologically characterized a novel ZNF767-BRAF fusion fo

78 The identified and chemically and biologically characterized active compound, and its deri

79 kinetics than those measured in studies with biologically/chemically reduced model clays.

80 regularly produce the most topologically and biologically coherent alignments.

81 Herein, we synthesized novel biologically compatible Zn(2+)/Ln(3+) metallacrowns (MCs

82 To ensure that priorities are biologically comprehensive, multiple dimensions of diver

83 These reductions in permeability can only be biologically consequential in contexts where the diffusi

84 a novel LC-MS data annotation method, termed Biologically Consistent Annotation (BioCAn), that combin

85 r energy-positive wastewater treatment as it biologically couples CO2 and O2 fluxes.

86 ract II, a software toolbox for detection of biologically derived compounds.

87 g g(-1)), whereas relative Cd amounts in the biologically detoxified heat stable protein fraction wer

88 butable to heterogeneity of MDD, aggregating biologically different subtypes.

89 utually exclusive manner in ccRCC and define biologically distinct subsets of ccRCC.

90 es, and provided stronger discrimination for biologically driven biotypes than symptom-based diagnose

91 troscopy, we show that mineral deposition is biologically driven.

92 entification of the characteristics that are biologically driving AF risk, and recent studies suggest

93 The continental shelves are the most biologically dynamic regions of the ocean, and they are

94 ms through which social disadvantage becomes biologically embedded and devising measurements that can

95 Storing biologically equivalent indels as distinct entries in da

96 ows proteins to rapidly fold to their native biologically functional conformations.

97 related gene sets they could discover within biologically heterogeneous data collections, hampering t

98 d L407F mutant allele of Arabidopsis cry1 is biologically hyperactive and seems to mimic the ATP-boun

99 is comprised of only two disjoint regions, a biologically impermissible region and a region where eac

100 thods for training these networks are either biologically implausible, and/or require a continuous, r

101 portant class of foraging decisions might be biologically implemented, but also for understanding the

102 the primate auditory cortex to extract these biologically important acoustic structures.

103 Together these results demonstrate a biologically important activity of manassantin in the co

104 dence that fast-translating codons can be as biologically important as pause sites in coordinating co

105 its our ability to uncover more complex, yet biologically important associations between multiple set

106 Collectively, our data point to a biologically important function of ALCAM in maintaining

107 ctivities and were converted to a variety of biologically important gamma-butyrolactones.

108 ities and completely distinguished the three biologically important hexoses (glucose, mannose, and ga

109 esis (MCE) device was used to quantitate two biologically important histidine dipeptides, carnosine a

110 sue autofluorescence arises from a number of biologically important metabolites, such as the reduced

111 mic the zinc finger domain, a ubiquitous and biologically important metal-binding tertiary motif, and

112 e also observed a change in the abundance of biologically important nutrients phosphorus and nickel a

113 Hydrogen sulfide (H2S) is a biologically important small gaseous molecule that exhib

114 ort abundant genetic interactions underlying biologically important traits, whereas quantitative gene

115 s); the pathways through which they interact biologically in individuals and within populations, and

116 kin-23 pathway is implicated genetically and biologically in the pathogenesis of Crohn's disease.

117 ivity of the composites over free enzymes in biologically incompatible conditions is emphasized in ma

118 twenty-six DHC-derived features that provide biologically independent information across a variety of

119 The unique spectral signatures and biologically inert compositions of surface-enhanced reso

120 GPCRs) from their active state back to their biologically inert ground state is an integral part of G

121 silicone spray adjuvants that are considered biologically inert potentiate viral pathogenicity in hon

122 a pragmatic knowledge base for carrying out biologically informative metabolite measurements.

123 abrication and optical characterization of a biologically inspired antireflective surface that emulat

124 g inspired by numerical analysis, and also a biologically inspired definition for robustness under th

125 To study molecularly defined cell functions, biologically inspired materials that mimic the nanoscale

126 lopments in the fields of soft photonics and biologically inspired optics, emphasizes the ties betwee

127 is a fundamental goal in the development of biologically inspired systems.

128 Latency is the most biologically interesting and clinically vexing feature o

129 metal-free alternative for the synthesis of biologically interesting arylated heterocycles under mil

130 ngth-based classification module to identify biologically interesting classes of ROH.

131 ticle images, it unfortunately obscures some biologically interesting components of a virus.

132 ad to the risk of unintentionally correcting biologically interesting factors attributed to batch eff

133 y, and evaluates differential expressions at biologically interesting levels.

134 ption factors (TFs) as unobserved, provide a biologically interpretable modelling framework, integrat

135 anscriptional regulation using a simple, yet biologically interpretable, model to find the logic by w

136 3D spectroscopic microimaging and to furnish biologically interpretable, quantitative, and dynamic mo

137 t DOM component, identified as the nonhumic, biologically labile, "N-peak", which may be responsible

138 score results in more accurate, robust, and biologically meaningful clustering results in both simul

139 nefit individuals in mixed-species groups in biologically meaningful contexts such as finding food in

140 breast cancer dataset identified interesting biologically meaningful differentially co-expressed (DCX

141 f injury, suggesting that this organ lacks a biologically meaningful endogenous stem cell pool.

142 oung children can be clustered into distinct biologically meaningful groups by their metabolomics pro

143 xistence of master regulators and identifies biologically meaningful master regulators.

144 ime intensive labeling, reduce the number of biologically meaningful parameters and/or rely on expens

145 e of network analysis techniques to generate biologically meaningful partitions of brain structures.

146 ficient computational methods that guarantee biologically meaningful predictions that obey the true p

147 sion and transcription regulation, which are biologically meaningful processes that may underlie asth

148 Such global bias, although biologically meaningful, is often neglected when interpr

149 teractions, as long as both are specific and biologically meaningful.

150 RNA polymerase II (Pol II) transcription or biologically meaningful.

151 entropy would render the resulting affinity biologically meaningless.

152 This study provides direct proof of a biologically mediated mechanism of volatile emission.

153 deterioration, which might be attributed to biologically mediated mechanisms.

154 hemically dominated process and that it is a biologically mediated one.

155 at non-crystalline U((IV)) generated through biologically mediated U((VI)) reduction is the predomina

156 Magnetic separation based on biologically-modified magnetic particles is a preconcent

157 ght on how efficient nature is in preventing biologically momentous photodamage.

158 eity in the host structure is maximal in the biologically most plausible parameter range, namely when

159 Finally, we use FORCE training to create two biologically motivated model circuits.

160 non-negative matrix factorization with a new biologically motivated regularization function.

161 We propose a novel, biologically motivated, Bayesian multitask approach, whi

162 educed resistance to crossflow, and that the biologically observed shapes of hair bundles of outer ha

163 plant phenotyping and the quantification of biologically or commercially relevant molecules, such as

164 To identify more biologically pertinent SSRs, we also developed several f

165 ction of coral reef systems is economically, biologically, physically and culturally immense.

166 ed through simple neuronal circuitry that is biologically plausible and can easily be accommodated in

167 mulate visual hallucinatory experiences in a biologically plausible and ecologically valid way.

168 main postsynaptic target cell types and with biologically plausible assumptions regarding the spatial

169 s a vital role in cell adhesion, making it a biologically plausible candidate gene in ARVC pathogenes

170 Most loci harbor biologically plausible candidate genes.

171 The findings suggest that biologically plausible genetic factors may alter suscept

172 Here, we demonstrate that one specific biologically plausible Hebb-type learning rule generates

173 pecific subsequences; and (iii) enabling the biologically plausible learning of sequences, consistent

174 Here we show that a biologically plausible learning rule can train such recu

175 ierarchical architectures and a broad set of biologically plausible learning rules generate approxima

176 Using these frameworks helps to establish biologically plausible links between endocrine mechanism

177 ow that network phase entrainment provides a biologically plausible mechanism for neural oddball dete

178 tivity-dependent regulation) is a simple and biologically plausible mechanism that meets this criteri

179 They offer a biologically plausible model of our findings, which they

180 hasizing the importance of this parameter in biologically plausible models of saccade initiation.

181 ebbian learning tested, the simpler and more biologically plausible option better matches the data.

182 For biologically plausible parameter values, we find that th

183 f trauma-related psychopathology and provide biologically plausible support for the self-medication h

184 Keven & Akins (K&A) propose a biologically plausible view of neonatal imitation based

185 But whereas many such models are biologically plausible, none have looked to the oculomot

186 Significant results, which appear biologically plausible, were also obtained for rare nasa

187 virus transmission in men is weak, although biologically plausible.

188 erves or increases topological complexity is biologically plausible.

189 Degradation of the biologically potent octapeptide angiotensin Ang II-(1-8)

190 protein concentrations, and seems to be the biologically preferred mechanism for forming membraneles

191 reason, the generation of entangled light in biologically produced fluorescent proteins would be prom

192 ge is partially suppressed in this system by biologically produced organics.

193 ting of photonic boxes into active layers of biologically produced recombinant fluorescent protein in

194 ause developmentally matured B cells undergo biologically programmed strand-specific DNA mutagenesis

195 l pores and form contiguous helices that are biologically promiscuous and hemolytic.

196 smaller than the known associations with the biologically proximal environmental factors alcohol cons

197 AC) indicated the chicken litter contained a biologically reactive fluorescent DOM component, identif

198 ctrophotometric-potentiometric titrations at biologically realistic GSH/Cu(I) ratios, enabled by our

199 ethod reduces this space in a systematic and biologically reasonable manner and converges to a likely

200 s multiplatform genomic data on the level of biologically related sets of genes, and our methods are

201 ver and specific immune cell miRNAs that are biologically related, and the consequences of immune-med

202 s approach allows the selective synthesis of biologically relevant 3,5-disubstituted oxazolone framew

203 A significant variety of biologically relevant AA side chains are tolerated inclu

204 ntifies four CpGs which can be mapped to two biologically relevant and functional genes.

205 o identification by existing techniques, are biologically relevant and thus MCbiclust has great poten

206 ns in memory.SIGNIFICANCE STATEMENT We use a biologically relevant approach-avoidance conflict test i

207 ata with a spatial resolution similar to the biologically relevant area encompassing population dynam

208 ts support gamma-OHPdG as a mechanism-based, biologically relevant biomarker for predicting the risk

209 Furthermore, we apply the TS to reveal biologically relevant changes in VE-cadherin tension tha

210 s concluded that PSI does not undergo NPQ in biologically relevant conditions in Arabidopsis thaliana

211 lity of the GSH-Cu(I) complexes formed under biologically relevant conditions remain controversial.

212 These experiments-performed under biologically relevant conditions-answer long-standing qu

213 ation constants) difficult to quantify under biologically relevant conditions.

214 ate and a product of protein lipidation in a biologically relevant context.

215 gh the propensity score incorporated several biologically relevant covariates, only height, weight, a

216 and activity, as demonstrated for a range of biologically relevant cyclic peptides, including somatos

217 ocellular carcinoma (HCC) dataset identifies biologically relevant DE isoforms.

218 t the potential of WGS strategies to enhance biologically relevant discoveries across the frequency s

219 ial cells show greatest NO release following biologically relevant doses of UV-A.

220 Thus, integrating biologically relevant epigenetic information (here, from

221 Genomic coordinates may be biologically relevant features from a variety of sources

222 Vbeta6 binds pro-TGF-beta1 in an orientation biologically relevant for force-dependent release of TGF

223 They are biologically relevant for their roles in cellular physio

224 f C. albicans cells by human immune cells in biologically relevant functional assays.

225 This approach requires biologically relevant gene sets, which are currently cur

226 capillaries and increased expression of five biologically relevant genes (CXCL11, CCL4, MS4A7, MS4A6A

227 To investigate the ability of clinically and biologically relevant genes and gene signatures (GSs) me

228 s is a good alternative for the synthesis of biologically relevant glycoconjugates.

229 poral datasets allowed detection of multiple biologically relevant groups (e.g., Wnt signaling, neura

230 mple protocol provides structurally complex, biologically relevant heterocycles in a one-pot operatio

231 ulticatalytic reactions for the synthesis of biologically relevant heterocyclic compounds.

232 (p </= 0.02) distinguishing the most common biologically relevant hexoses using only femtomoles of h

233 g of infection was unknown, or following non-biologically relevant inoculation routes.

234 e based nanosensor, with response across the biologically relevant K(+) concentrations, from the extr

235 demonstrated in its ability to functionalize biologically relevant l-proline and l-trans-hydroxyproli

236 ressed lncRNAs in MDS and further prioritize biologically relevant lncRNAs using the NLCFA.

237 which greatly hinders their applications in biologically relevant media.

238 nto extensive networks at the interface with biologically relevant membrane systems or other soft sur

239 To do so, we explore the utility of a highly biologically relevant model system, mammalian cells unde

240 , representing the transmitted virus, a more biologically relevant model.

241 In this study, we aimed to identify biologically relevant molecular endotypes in patients wi

242 stems chemistry of the three classes of (pre)biologically relevant molecules and their oligomers, in

243 pporting the possibility of the emergence of biologically relevant molecules in a reducing atmosphere

244 Selective deuteration of drugs and biologically relevant molecules is becoming increasingly

245 bility of SCFAs and their incorporation into biologically relevant molecules was quantified.

246 rincipal component analysis (PCA) to extract biologically relevant motions from atomic trajectories o

247 O can achieve better performance in building biologically relevant networks than purely data-driven m

248 nerating realistic gene expression data from biologically relevant networks that can be user selected

249 ersible exchange with studies on a series of biologically relevant nicotinamides and methyl nicotinat

250 l physical insulation, which is a single and biologically relevant parameter.

251 D subjects based on endophenotypes unraveled biologically relevant pathway disruption and revealed a

252 he tangerine and red tomato juices differ in biologically relevant phytochemicals beyond carotenoids.

253 hylation, acetylation, or phosphorylation in biologically relevant positions.

254 iomolecular systems exhibit many dynamic and biologically relevant properties, such as conformational

255 g can be used to reliably identify and model biologically relevant protein assemblies at the proteome

256 teins are spatially proximal in at least one biologically relevant protein conformation within the fa

257 hout affecting the structure and function of biologically relevant proteins.

258 impact within the proteome, establishes the biologically relevant reactivity possible with this new

259 for -omics data exploitation, giving rise to biologically relevant results.

260 ibility that this unusual dimer might have a biologically relevant role in the regulation of full-len

261 Further, biologically relevant scaffolds, such as alpha-quaternar

262 resolutions are often too coarse relative to biologically relevant scales.

263 visualize GNR diffusion and distribution in biologically relevant scenarios ex vivo, in vitro and in

264 ted fatty acids, generating an assortment of biologically relevant signaling mediators.

265 Achieving this control directly in a biologically relevant solvent, without affecting cell vi

266 A new synthetic approach to biologically relevant spiro[pyrrolidine-3,3'-oxindoles]

267 human amygdala coordinates how we respond to biologically relevant stimuli, such as threat or reward.

268 using annotation which does not over-report biologically relevant structural details of identified l

269 tumors can be divided into more precise and biologically relevant subgroups has demanded a more glob

270 entity revealed a series of cancer genes and biologically relevant subtype diversity that represent a

271 al stability predictions for a wide range of biologically relevant systems.

272 activity that could be applied to many other biologically relevant targets.

273 myosin motors, and cross-linking proteins at biologically relevant time and length scales.

274 search for, detect, and fix DNA damage on a biologically relevant time scale.

275 e protein, can reorient in the membrane on a biologically relevant time scale.

276 Microvascular location is likely to be biologically relevant to many diseases, and so our spati

277 olomics data amenable to analyses describing biologically relevant variability, we propose mixture mo

278 acterize egg-shape diversity in terms of two biologically relevant variables, asymmetry and elliptici

279 in these highly similar Galpha proteins are biologically relevant, and some proteins are more flexib

280 ortant insights into how the introduction of biologically relevant, but poorly understood, modificati

281 Thus, we have discovered a new biologically relevant, lumisterogenic pathway, the metab

282 vant alterations, validating this dataset as biologically relevant.

283 Overall cellular responses to biologically-relevant stimuli are mediated by networks o

284 ns that its inhibition produces effects that biologically resemble the egress phenotype taken on by C

285 the flows of several harmful compounds into biologically rich surface water.

286 n coral reefs are protected ecologically and biologically significant areas that support global fishe

287 scle fibers release exosomes which can exert biologically significant effects on recipient cells, and

288 l and functional alterations are elicited by biologically significant electric fields and by naturall

289 tically conserved; strongly suggesting it is biologically significant.

290 ontologically defined biological pathways in biologically similar samples have similar behavior.

291 ulated flows of water-soluble compounds into biologically sparse deep water by 55%, while decreasing

292 d determine the set of analytes that exhibit biologically stable baselines after technical variabilit

293 d RNA probes because they are chemically and biologically stable, easily synthesized, and hybridize e

294 Biologically, the AR pathway has cross-talk with several

295 elements dissipate, and C) RAMP can identify biologically tolerable diversity of a metabolic network

296 d cardiomyocytes has largely been limited by biologically undefined factors including 3D nature of em

297 demism, and vulnerability may underrepresent biologically unique species as well as their functional

298 Aging is a biologically universal event, and yet the key events tha

299 mony of the regulatory processes, ruling out biologically unrealistic mechanisms.

300 ated with radiation and temozolomide and was biologically validated in an independent data set.