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1 nt for our mechanistic understanding of cell biology.
2 such as cancer, developmental, and stem cell biology.
3 oblem solving is debated within the field of biology.
4 tion their proteins is a key problem in cell biology.
5 s is a widely-used method for assessing cell biology.
6 organs is a major question in developmental biology.
7 at, 30 years later, would be called chemical biology.
8 gressive exocrine tumor with largely unknown biology.
9 implications for their broader evolutionary biology.
10 e examples of its power when applied to cell biology.
11 ancing our understanding of RNA functions in biology.
12 is is an important question in developmental biology.
13 ty of eukaryotes represent a major enigma in biology.
14 thways that predict aggressive breast cancer biology.
15 tial context is a long-standing challenge in biology.
16 nate how prebiotic chemistry transitioned to biology.
17 ytic repertoire to functions that are new to biology.
18 sis thaliana), preventing its use in plastid biology.
19 ematopoietic stem and progenitor cell (HSPC) biology.
20 nome transfer in biotechnology and synthetic biology.
21 synthesis, medicinal chemistry, and chemical biology.
22 for the exploration of revascularized islet biology.
23 a quintessential challenge in global change biology.
24 e strain will assist in studies of iNKT cell biology.
25 protocols, and are broadly applicable across biology.
26 lnesses and so far little is known about its biology.
27 ant role in tissue homeostasis and stem cell biology.
28 ogy), requires a detailed knowledge of tumor biology.
29 are not guided by individual risk or disease biology.
30 d therapeutic strategies that target disease biology.
31 o distinct diagnoses based on the underlying biology.
32 g pathogens to discover disease-related cell biology.
33 esponse to increased understanding of cancer biology.
34 f interest to neuroscience and developmental biology.
35 ing telomere function and its roles in human biology.
36 the nexus of chemical genomics and synthetic biology.
37 seen an explosion in our knowledge of HLA-G biology.
38 as diverse as atmospheric chemistry and cell biology.
39 a structurally novel chemical probe for IAP biology.
40 amework to tackle lingering questions in DUB biology.
41 l for population monitoring and conservation biology.
42 yse the functional role of IL-31 in basophil biology.
43 ects of therapeutic intervention and disease biology.
44 xic stress has a strong impact on tumor cell biology.
45 the types of investigation possible in cell biology.
46 e diverse, yet with a poorly understood cell biology.
47 lular populations remains a key challenge in biology.
48 fitness is a central concept in evolutionary biology.
49 aradigm shift from descriptive to predictive biology.
50 and suggest that they had a mushroom feeding biology.
51 dual role that each has in mitochondrial RNA biology.
52 part of the routine data analysis in systems biology.
53 ology each has its ancestry in developmental biology.
54 ental change is a major goal of evolutionary biology.
55 with the selection of my research topic: RNA biology.
56 f speciation is a major goal in evolutionary biology.
57 synergy of computer science, statistics and biology.
58 fetal testis and alteration of the germ cell biology.
59 pportunity for medicine and also basic human biology.
60 ontributions of these essential nutrients in biology.
62 of the Cell Ontology based on standard cell biology and biochemistry textbooks and review articles.
65 d we offer a perspective on emerging network biology and computational solutions to exploit these phe
66 de a greater level of understanding of miRNA biology and critical insights into the many translationa
68 has focused research on understanding virus biology and developing a suite of strategies for disease
70 tion of gas-phase measurements in structural biology and drug discovery, the factors that govern prot
73 lutionary biology with mechanistic molecular biology and ecology, promising applications in medicine
75 acilitate further understanding of stem cell biology and engineering of stem cells for therapeutic ap
76 clusion, this study gives insights into apoE biology and establishes a robust screening system to mon
77 constitute a powerful resource for nematode biology and foreshadow similar atlases for other organis
78 ents for EBOV, a better understanding of the biology and functions of EBOV-host interactions that pro
79 ancet in 2012, advances in understanding the biology and genetics of non-Hodgkin lymphoma and the ava
82 s in the fields of computational and systems biology and highlight opportunities for researchers to u
83 s-answer long-standing questions in membrane biology and illustrate a fundamentally new approach for
85 and BB0323, play distinct roles in pathogen biology and infectivity although a significance of their
86 ncers continue to enhance its role in cancer biology and its utility as a biomarker and therapeutic t
91 wdsourcing knowledgebase that centralizes EV biology and methodology with the goal of stimulating aut
93 n that existing technology provides (systems biology and network medicine) so diagnosis, stratificati
95 many disciplines, especially in evolutionary biology and oncology, the developmental perspective is b
96 netics has greatly enhanced the study of the biology and pathology associated with parasites of the p
97 esponse to DEB-TACE is correlated with tumor biology and patients at risk for posttransplantation rec
98 this review, we provide an overview of FGF23 biology and physiology, summarize clinical outcomes that
99 brafish as a model organism in developmental biology and regeneration research, genetic techniques en
100 f KLFs in mammalian embryogenesis, stem cell biology and regeneration, as revealed by studies of anim
102 es the first comprehensive overview of DLBCL biology and the basis for future precision medicine appr
103 tical for our future understanding of cancer biology and the development and implementation of novel
104 lso a valuable resource for understanding GC biology and the mechanistic details of GR-regulated tran
105 luable resource to the field of inflammation biology and will be an important asset in future anti-in
106 ve mutations in a patient's cancer drive its biology and, by extension, its clinical features and tre
108 f inorganic nanoparticle colloids in optics, biology, and energy, their surface chemistry has become
109 l to understanding chemical and evolutionary biology, and for the exploitation of enzymes for biotech
110 chemical biology, proteomics, genomics, cell biology, and genetics that have propelled new discoverie
112 an excellent model for the study of integrin biology, and it has become clear that integrin outside-i
113 natural law making important predictions in biology, and its influence has spread from evolutionary
114 ors (MBIs) are widely employed in chemistry, biology, and medicine because of their exquisite specifi
116 elopmental biology, retinal physiology, cell biology, and other investigations, has been limited by l
117 new reactivity, transformations not known in biology, and reactivity inaccessible by small-molecule c
118 s have described roles for CXCR7 in vascular biology, and the downstream mechanism of CXCR7 in angiog
119 structures is a major theme in developmental biology, and the inter-relationship between spacing and
120 tions, its aberrations affect AML evolution, biology, and therapy response and usually predict poor p
124 DS AND We applied a well-established network biology approach (master regulator analysis) to combine
125 entually succeed, I suggest that a synthetic biology approach - moving free-living nematodes towards
127 rcome this barrier, we developed a synthetic-biology approach based on a technique known as codon shu
128 e therefore developed InFlo, a novel systems biology approach for characterizing complex biological p
129 the authors use for the first time a systems biology approach to comprehensively evaluate clinical pa
130 filament assembly, we have used a synthetic biology approach to reconstitute, in a nonnative heterol
137 phA4 has been found to play a role in cancer biology as well as in the pathogenesis of several neurol
138 es for scientific discovery in developmental biology as well as in translational research, but whethe
139 previously unresolved issues related to BDNF biology, as well as how BDNF may function as a downstrea
140 new researchers, without an explicit cancer biology background, a contemporary interpretation of bot
141 thogen panel (RP panel) is a novel molecular biology-based assay, developed by GenMark Diagnostics, I
142 are ideally suited for comparative chromatin biology because sequencing of numerous genomes from many
144 th Isomap and Laplacian Eigenmaps, synthetic biology biobircks are successfully visualized in two dim
146 sing an experimental approach combining cell biology, biochemistry, and mass spectrometry, we show th
147 CDDB has found broad usage by the structural biology, bioinformatics, analytical and pharmaceutical c
148 copy that helped answer questions about cell biology but also by clever genetic manipulations that di
149 Phenotyping is important to understand plant biology, but current solutions are costly, not versatile
150 pe is a fundamental expression of organismal biology, but its quantitative reconstruction in fossil v
152 a key fuel-cell reaction also carried out in biology by oxidase enzymes, includes the critical O-O bo
153 erate research into Candida pathogenesis and biology, by curating the scientific literature in real t
155 logy, metabolism, endocrinology, and systems biology discussed genetic and environmental determinants
157 ionary mechanisms, neurobiology, and systems biology each has its ancestry in developmental biology.
158 emethylation and as a component of synthetic biology efforts to valorize previously underused aromati
160 l to solving contemporary problems in modern biology, especially in domains such as cancer and system
161 There is a growing interest in modern cell biology for methods enabling force measurements in vivo.
166 Finally, we summarize recent progress in GLP biology, highlighting emerging concepts and scientific i
167 er exosomes in these three aspects of cancer biology, highlighting recent advances and potential limi
168 ur data provide mechanistic insight into RNR biology, highlighting RRM2B as a hypoxic-specific, anti-
169 tabolomics answers a fundamental question in biology: How does metabolism respond to genetic, environ
172 e natural history, ecology, and evolutionary biology in addition to genomics studies that are already
173 s is known about these basic aspects of cell biology in early-diverging Apicomplexan parasites, which
174 sequence, little is known regarding R. typhi biology in flea vectors that, importantly, do not suffer
176 nal cells and has implications for vitamin D biology in multiple sclerosis and perhaps other autoimmu
179 dedicated to different research areas of RNA biology including RNA structure analysis, RNA alignment,
181 ces several aspects of extracellular vesicle biology, including cargo sorting, release, and bioactivi
182 rofessional responsibilities as professor of biology, including climbing tall trees for her canopy re
183 ow that autophagy has a much broader role in biology, including organellar remodeling, protein and or
184 tand many natural phenomena, particularly in biology, including the cell-fate decision in development
186 ch field spanning from biochemistry and cell biology into nutritional sciences, environmental medicin
187 he spectrum of molecular biology to cellular biology, involving fields such as cancer, developmental,
188 aluating gene networks with respect to known biology is a common task but often a computationally cos
192 proliferation and disease, micro-RNA (miRNA) biology is of great importance and a potential therapeut
198 We cite specific examples from the synthetic biology literature that illustrate these principles and
199 didates not previously implicated in ciliary biology localized to cilia and further investigated ENKU
200 nd, with examples, demonstrate how synthetic biology may maximize CO2 uptake within and above storage
201 This knowledge can be obtained with systems biology/medicine approaches that account for the complex
205 romising opportunities for further synthetic biology modification and for a variety of biotechnologic
207 that the field of extracellular vesicle (EV) biology needs more transparent reporting to facilitate i
209 t challenge with relevance both to the basic biology of animal communication and to biomedicine.
210 tudies, and clinical trials, we examined the biology of AR and AR-related pathways, the potential for
211 obust cell line to study the novel molecular biology of ascovirus replication in vitro is lacking.
212 e to large gaps in our knowledge of the cell biology of astrocytes and the mechanisms they use to int
214 ed and analyzed to provide insights into the biology of cancer spread and response to therapy and to
217 he Musashi (Msi) have been implicated in the biology of different stem cell types, yet they have not
218 emonstrate its power to represent underlying biology of gene expression in microarray and RNA-Seq dat
219 s deficiency hampers investigations into the biology of glycan-binding proteins, which in turn compli
220 ent a new and simple tool to investigate the biology of HGSC, and the ID8 cell lines are freely avail
223 t is essential for understanding the complex biology of living organisms and of disease state and pro
225 -STAT activation, the cellular and molecular biology of myeloproliferative neoplasms (MPN) remains in
227 ew of the ecology and molecular and cellular biology of New World arenaviruses, as well as a discussi
228 primarily on the biochemistry and molecular biology of PARP-1 in DNA damage detection and repair, th
235 develop a better understanding of the basic biology of this parasite and how it interacts with its r
236 agulation cascade, representing the relevant biology of thrombin generation and the subsequent fibrin
238 and the results revealed new insights in the biology of tRNASec, led to the discovery of a novel bact
239 discuss how these marked differences in the biology of vaginal infection between these otherwise gen
241 l of biological disciplines." Genetics, cell biology, oncology, immunology, evolutionary mechanisms,
246 t of methodological approaches from chemical biology, proteomics, genomics, cell biology, and genetic
247 ide a promising tool for human developmental biology, regenerative therapies, disease modeling, and d
253 gms, examples, and techniques, developmental biology remains vigorous, pluripotent, and relatively un
255 c structures and functions of DNA and RNA in biology requires tools that can selectively and intimate
256 ever-increasing amounts of data produced in biology research, scientists are in need of efficient da
258 a common research subject for developmental biology, retinal physiology, cell biology, and other inv
259 de: Discussed herein is the ability to adapt biology's mechanisms for innovation and optimization to
261 along with Wang et al. (2017) in Nature Cell Biology, show how PAR protein oligomerization can dynami
262 myces cerevisiae as a platform for synthetic biology, strain engineering remains slow and laborious.
263 and integrate the complexities of lymphatic biology, stromal variability, chemoattractant distributi
265 In addition, we address new areas of lncRNA biology, such as the functions of enhancer RNAs, circula
268 basic research, biotechnology and synthetic biology that involve the multistep engineering of plasti
269 ese data identify LDIP as a new player in LD biology that modulates both LD size and cellular neutral
270 ng for two basic assumptions in Schwann cell biology: that myelin and Remak cells generate the elonga
272 one of the most challenging tasks in systems biology to automatically identify protein complexes.
273 l research, across the spectrum of molecular biology to cellular biology, involving fields such as ca
274 n widely studied in a variety of fields from biology to computer science, still little is known about
275 d its influence has spread from evolutionary biology to other fields including the social sciences.
276 yonic development and for applying stem cell biology to regenerative medicine and disease modeling.
277 unt of Semantic Web based knowledge bases in biology to use in machine learning and data analytics.
278 will be a valuable addition to the synthetic biology toolkit, facilitating the understanding of natur
279 nhibitors that we show to be useful chemical biology tools especially in determination of dissociatio
283 aches are adding to our understanding of the biology underlying disease development and progression.
286 d-20th century, reductionism as a concept in biology was challenged by key thinkers, including Ludwig
288 To examine its role in endothelial cell (EC) biology, we generated mice with catalytic inactivation o
289 part of the Reproducibility Project: Cancer Biology, we published a Registered Report, that describe
290 part of the Reproducibility Project: Cancer Biology, we published a Registered Report, that describe
291 serving as a surrogate for underlying tumor biology which can be utilized for prioritization of HCC
292 understanding disease mechanisms and target biology, which facilitate exciting translation of this r
293 other side chains in the protein scaffold in biology, which may alter the apparent DeltaDeltaGsc(o).
296 olistic approaches, integrating evolutionary biology with mechanistic molecular biology and ecology,
297 able, rapid progress in combining structural biology with other techniques is revealing the similarit
298 portant and widely used algorithm in systems biology, with applications in protein function predictio
299 ions is a long-standing goal in evolutionary biology, with important implications for conservation, m
300 red proteins play important roles throughout biology, yet our understanding of the relationship betwe
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