ライフサイエンスコーパス: biomaterial

1 nse fibrin matrix and can be used as healing biomaterial.

2 e extracellular matrix and a common clinical biomaterial.

3 ntism and for producing the world's toughest biomaterial.

4 biochemical properties that make it an ideal biomaterial.

5 ot, a dynamic and heterogeneous fibrin-based biomaterial.

6 e electronic devices, sensors and structural biomaterials.

7 its sustainable transformation to fuels and biomaterials.

8 ydrides (NCAs) are one of the most important biomaterials.

9 olled antibacterial release in this class of biomaterials.

10 s in both aerospace development and metallic biomaterials.

11 for such dangerous and time-sensitive target biomaterials.

12 ptides to the development of light-sensitive biomaterials.

13 ility, stability and modularity of synthetic biomaterials.

14 which extend to developing new antibacterial biomaterials.

15 otechnological utilization of these abundant biomaterials.

16 ptimizing manufacturing, and screening drugs/biomaterials.

17 array of invertebrate and vertebrate animal biomaterials.

18 using 3D bioprinted cardiac patches, free of biomaterials.

19 operties or designing novel xyloglucan-based biomaterials.

20 essential in predicting GNR interaction with biomaterials.

21 is imperative to develop novel antimicrobial biomaterials.

22 s a reinforcing phase of polymeric composite biomaterials.

23 ee mechanical characterization of tissue and biomaterials.

24 lopment of new types of mechanically tunable biomaterials.

25 easingly important role in drug delivery and biomaterials.

26 terionic materials and their applications as biomaterials.

27 lecular hydrogels/hydrogelators as molecular biomaterials.

28 iology, therapeutic protein development, and biomaterials.

29 in organic electronics, polymer science and biomaterials.

30 is known regarding cells' global response to biomaterials.

31 parative responses associated with implanted biomaterials.

32 ectivity, and minimally disruptive impact on biomaterials.

33 feedstock for the production of biofuels and biomaterials.

34 insights have yet to be applied in designing biomaterials.

35 the GONR-FET sensor is suitable for sensing biomaterials.

36 rts to replicate silk-based high-performance biomaterials.

37 ogical assembly to engineering peptide-based biomaterials.

38 es with the aim to arrive at multi-component biomaterials.

39 ailable for conjugations of biomolecules and biomaterials.

40 lications is as a marker in the detection of biomaterials.

41 means to create durable, biologically active biomaterials.

42 mesothelium of the peritoneal membrane via a biomaterial abrogates the release of active MMP2 in resp

43 ants of one of the most widely used hydrogel biomaterials, alginate.

44 he system is the use of natural silk protein biomaterial allowing us to leverage its biocompatibility

45 upramolecular hydrogel may be beneficial for biomaterial and biomedical applications.

46 reading by overriding the soft signal of the biomaterial and impacting actin organization and adhesio

47 tween the active locales of enzymes or other biomaterials and a transducer surface.

48 these approaches, outlines the use of common biomaterials and advanced hybrid scaffolds, and describe

49 approach for the high-resolution imaging of biomaterials and biological systems.

50 understanding the structure and function of biomaterials and biological systems.

51 Implanted biomaterials and biomedical devices generally induce for

52 rating their practical utility in functional biomaterials and biotechnology.

53 result in a more than 1000-fold reduction in biomaterials and cells consumption when engineering opti

54 e wide biomedical applications especially in biomaterials and drug delivery field.

55 d in fields as diverse as polymer chemistry, biomaterials and hydrogels, dynamic combinatorial chemis

56 leading experts in the fields of stem cells, biomaterials and immunoregulation.

57 ty measurement of aqueous solutions and soft biomaterials and is of great value to cryopreservation o

58 ng healthcare in low-resource settings using biomaterials and nanoplasmonics.

59 ons from disease modulation to the design of biomaterials and peptides in synthetic biology.

60 new materials such as flexible solar panels, biomaterials and printable tissues, new catalysts, polym

61 een increasingly tailored for characterizing biomaterials and probing their interactions with biologi

62 micropatterning to the synthesis of complex biomaterials and sequence-controlled polymers.

63 ystem constitutes a living interface between biomaterials and stem cells.

64 building blocks for future high-performance biomaterials and textiles due to their high ultimate str

65 as those concerning the provenance of human biomaterials and the use of gene-editing technologies.

66 icrobial and therapeutic effects of TA-nHP66 biomaterials and their in vivo silver release kinetics.

67 ive roles of polarized macrophages encompass biomaterials and tissue remodeling needs, yet harnessing

68 Engineering the interface between biomaterials and tissues is important to increase implan

69 ers from the low scattering cross-section of biomaterials and X-ray damage to the sample.

70 highlight the role of mucus as a responsive biomaterial, and reveal a mechanism of mucus restructuri

71 us starfish, extract and separate the active biomaterials, and compare the effects of each fraction o

72 hod for the development of self-synthesizing biomaterials, and may shed light on understanding life's

73 n the fungal decay process of lignocellulose biomaterials, and more broadly fungal metabolism, has im

74 Biomaterials, and particularly hydrogels, have been deve

75 approaches for developing oxygen-generating biomaterials, and their potential as 3D scaffolds for re

76 Recently, the biomaterials application of GNR has been explored, for e

77 e mechanical integrity is important for most biomaterial applications, proper function and integratio

78 Self-assembled biomaterials are an important class of materials that ca

79 nanostructure of bone, nanodopant composite biomaterials are gaining special attention for their abi

80 eraction with natural tissue, supramolecular biomaterials are promising candidates for regenerative m

81 , lipids, scaffolds, microneedles, and other biomaterials are rapidly emerging as technologies to imp

82 We refer to these hybrid biomaterials as 'enveloped protein nanocages' (EPNs).

83 mensional myocardial tissue constructs using biomaterials as an implantable hiPSC-derived myocardium

84 this report, we used cell walls from natural biomaterials as non-toxic, stable, and inexpensive suppo

85 ly stable pectin-coated LPN from all natural biomaterials as potential oral delivery vehicles.

86 made possible through the unique features of biomaterials, as well as the important questions for fur

87 uss the properties of several supramolecular biomaterials, as well as their applications in drug deli

88 phosphoproteomic method was used to identify biomaterial-associated changes in the phosphorylation pa

89 Despite many advances, biomaterial-associated infections continue to be a major

90 hould be compatible with other viable active biomaterials at interfaces, and we envision its use to p

91 elease suggests that the potential impact of biomaterials at the abutment or bone interfaces may have

92 chemical control of charge transport across biomaterial-based devices.

93 Biomaterial-based immunomodulation strategies can signif

94 Biomaterial-based presentation of regulatory basement me

95 ing advances arises the prospect of improved biomaterial-based therapies, yet practical constraints f

96 Biomaterial-based tissue culture platforms have emerged

97 e method of fibrosis inhibition, and improve biomaterial biocompatibility without the need for broad

98 lecules could find use in polymer chemistry, biomaterials, biomedical imaging, and protein tagging.

99 l for use in a range of applications such as biomaterials, biorecognition, nanomachines and as therap

100 Molecules can be immobilized onto biomaterials by a chemical vapor deposition (CVD) coatin

101 ow that the host response to a proangiogenic biomaterial can be drastically affected by the mode of i

102 cisely controlled integrin activation from a biomaterial can be harnessed to direct therapeutic vesse

103 Specific polymeric biomaterials can be prepared for use in varied medical a

104 and immune-mediated foreign body response to biomaterials can compromise the performance of implanted

105 ns between inflammatory cells and injectable biomaterials can induce beneficial extracellular matrix

106 nd excellent water retention, hydrogel-based biomaterials can mimic critical properties of the native

107 Such tissue-like biomaterials can provide an appropriate microenvironment

108 ted tissue engineers the ability to assemble biomaterials, cells, and signaling molecules into anatom

109 increased following implantation of multiple biomaterial classes: ceramic, polymer and hydrogel.

110 ons of supramolecular hydrogels as molecular biomaterials, classified by their applications in cell c

111 the chemical engineering, drug delivery and biomaterial communities.

112 MS, ESI-MS, and IM-MS to the polymer-peptide biomaterial confirmed its composition.

113 Hence, as a simple but intelligent biomaterial consisting of mainly edible starch and RB po

114 More sophisticated biomaterials could be built if both the structure of the

115 pernyi silk meets the major biochemical and biomaterial criteria for spinal repair, and may have pot

116 with orthotopic xenograft assays, the novel biomaterial cultures we developed better preserved the p

117 Lastly, better controlled biomaterial degradation significantly improved osteointe

118 , hemicellulose, and lignin as well as other biomaterials derived from wood, in regard to their major

119 body responses, which will lead to improved biomaterial design and will reduce foreign body reaction

120 ghput bioassays that, if incorporated into a biomaterial design framework, could help achieve unprece

121 Our strategy provides a new avenue in biomaterial design to advance tissue engineering and cel

122 Despite the increasing sophistication of biomaterials design and functional characterization stud

123 The vast opportunities for biomaterials design and functionality enabled by mimicki

124 orporation of next-generation bioassays into biomaterials design to effectively optimize function whi

125 ation of cell fusion and can be exploited in biomaterials design to induce desirable biomaterial-tiss

126 This framework can inspire biomaterials designs that maximize functionality and tra

127 We study a unique biomaterial developed from fungal mycelium, the vegetati

128 Biomaterial development for tissue engineering applicati

129 ces for a range of applications ranging from biomaterials development to peptides with therapeutic us

130 ite its growing importance in biology and in biomaterials development, liquid-liquid phase separation

131 oxyalkanoates (PHAs) are excellent candidate biomaterials due to their exceptional biodegradability a

132 es (e.g., protein, gene, and cell based) and biomaterials (e.g., resorbable, nonresorbable, and 3-dim

133 In this study, we present a brain-mimetic biomaterial ECM platform for 3D culturing of patient-der

134 in live microalgae is crucial for efficient biomaterial engineering, but conventional methods fail t

135 lization strategy for the next generation of biomaterial engineering.

136 anipulating the adaptive immune system using biomaterials engineering may support the development of

137 vancements in systems and synthetic biology, biomaterials engineering, and traditional microbiology.

138 ure of valvular interstitial cells (VICs) in biomaterial environments containing pathological amounts

139 tal advance in the generation of crosslinked biomaterials, especially in the form of soft matter coll

140 These biomaterials establish a highly efficient model of PKD c

141 inders their widespread use as bioenergy and biomaterial feedstocks.

142 udy, we focus on a prototypical hierarchical biomaterial, fibrin, which is one of the most resilient

143 gro-industrial residues is promising for the biomaterial field, especially in the preparation of hydr

144 e nonfouling elastomer is a highly promising biomaterial for biomedical and engineering applications.

145 disrupt CIL, thus illustrating a new kind of biomaterial for regulating cell behavior.

146 resented for use as a tunable, dual response biomaterial for the capture and release of circulating t

147 n be applied toward the synthesis of complex biomaterials for a wide range of applications.

148 ng supramolecular hydrogelators as molecular biomaterials for addressing the societal needs at variou

149 ly of peptide nanotubes (PNTs) would provide biomaterials for applications in nanotechnology and synt

150 a versatile tool to combine gene therapy and biomaterials for applications in regenerative medicine.

151 ions and as an important design parameter of biomaterials for cell culture.

152 progress toward the development of SMP-based biomaterials for clinically relevant biomedical applicat

153 Correspondingly, capability of nano-biomaterials for developing highly sensitive and more ef

154 nite for preparation of nano-engineered nano/biomaterials for food and pharmaceutical applications.

155 drogels are an especially appealing class of biomaterials for gene delivery vehicles as they can be i

156 The increasing progress in using nano-biomaterials for medical purposes has opened new horizon

157 ned hybrid hydrogels have potential as novel biomaterials for pharmaceutical and biomedical applicati

158 inning is explored for reconstructing living biomaterials for regenerative biology and medicine.

159 lar polymers into multi-component functional biomaterials for regenerative medicine applications.

160 le mice were extracted and encapsulated into biomaterials for subsequent transplantation into adult m

161 verview of the latest studies on engineering biomaterials for the enhancement of anticancer immunity

162 The promise of (nano)biomaterials for the treatment of cancer can only be rea

163 roperties of soft tissue and are widely used biomaterials for tissue engineering and regenerative med

164 The resulting hybrid biomaterials form thermotropic columnar hexagonal mesoph

165 and infection prevention in response to new biomaterial formulations for craniofacial tissue enginee

166 This class of biomaterials has opened a new window for overcoming the

167 Future work exploiting engineered biomaterials has the potential to generate manufacturing

168 ues from 3D printing, tissue engineering and biomaterials has yielded a new class of engineered biolo

169 e excellent mechanical properties of natural biomaterials have attracted intense attention from resea

170 arbon nano tubes, polymers, microspheres and biomaterials have been evoked.

171 In recent years, synthetic biomaterials have been used to study a wide range of out

172 Biomaterials have dramatically increased in functionalit

173 These novel triacrylate-based biomaterials have potential to enable novel regenerative

174 combine synthetic nanoparticles with natural biomaterials have recently gained much attention.

175 Recent studies on biomaterials have revealed that many structural biomater

176 Biological machines consisting of cells and biomaterials have the potential to dynamically sense, pr

177 injuries, a variety of natural and synthetic biomaterials have undergone robust research, leading to

178 Injectable, acellular biomaterials hold promise to limit left ventricular remo

179 genicity in a clinically relevant xenogeneic biomaterial (i.e. BP) and further validates a rapid, hig

180 omplex tissue organization using appropriate biomaterials impacts success in tissue engineering endea

181 s of cellular and molecular events following biomaterial implantation poses an important bottleneck f

182 Upon subcutaneous biomaterial implantation, Sox10(+) stem cells were activ

183 Porous silica is an attractive biomaterial in many applications, including drug-deliver

184 l reports have highlighted the importance of biomaterials in assisting directed differentiation.

185 principal barrier for expanding use of such biomaterials in clinical practice.

186 , which has implications for use of such ECM biomaterials in clinical practice.

187 show great value in the fulfilment of smart biomaterials in emerging areas.

188 Many structural biomaterials in nature are found to have modulus mismatc

189 daptive immune system responses to implanted biomaterials in rodents and non-human primates.

190 hat compared the performance of PRF to other biomaterials in the treatment of Miller Class I or II gi

191 roper function and integration also requires biomaterial incorporation into complex surrounding tissu

192 etic or biologic meshes has reported chronic biomaterial infections and high hernia recurrence rates.

193 esponse and develop strategies for effective biomaterial integration.

194 Research over the past decade on the cell-biomaterial interface has shifted to the third dimension

195 olic synthons as the building blocks for new biomaterials is based on the early application and succe

196 asic concept of many of these supramolecular biomaterials is based on their ability to adapt to cell

197 vascular networks within cell-laden hydrogel biomaterials is introduced.

198 The use of tough hydrogels as biomaterials is limited as a consequence of time-consumi

199 The issue with porous silica biomaterials is the rate at which they resorb and the si

200 A remarkable feature of biomaterials is their ability to deform in response to c

201 ple length scales are found in numerous hard biomaterials, like bone, wood, and glass sponge skeleton

202 Biomaterials made of calcium phosphate or bioactive glas

203 Therefore, the TA-nHP66 scaffold biomaterials may be further explored as an effective adj

204 eiling the key components that contribute to biomaterial-mediated inflammatory responses.

205 The use of 3D biomaterial microarrays can, if optimized correctly, res

206 Three dimensional (3D) biomaterial microarrays hold enormous promise for regene

207 molecules for bottom-up self-assembly of new biomaterials mimicking the ECM to directly impact cell b

208 erties as well as to rationally design novel biomaterials of required mechanical strength with desire

209 Herein, we discuss the impact of biomaterials on the iPSC field, from derivation to tissu

210 Incorporation of GAGs into biomaterials opens up new routes for the presentation of

211 s can open up opportunities in extracellular biomaterial or bioelectric systems.

212 We postulate possibilities to utilize biomaterial physicochemical modifications to modulate th

213 e used a fully defined, 3D, thermoresponsive biomaterial platform to rapidly generate large numbers o

214 omprised of two synthetic controlled-release biomaterials, poly(lactide-co-glycolide; PLGA) micropart

215 Injection of a conductive biomaterial polymer that restores impulse propagation co

216 his goal GICs were incorporated into various biomaterials possessing antibacterial activities.

217 examples of these functional supramolecular biomaterials reaching the clinic have been reported.

218 The topography of a biomaterial regulates cellular interactions and determin

219 ion sensing, drug delivery, data storage and biomaterial replacement.

220 Thus, 3D microscale biomaterials represent a promising platform for the tran

221 gical activity, providing a new resource for biomaterials research and further understanding of regen

222 Lattice defects at the biomaterial's surface greatly promote interaction with p

223 ization in material fabrication, hundreds of biomaterial samples can be rapidly produced, which can t

224 tures of the microenvironment, including the biomaterial scaffold and the niche constructed by cells

225 une-mediated tissue regeneration driven by a biomaterial scaffold is emerging as an innovative regene

226 arvest autoimmune T cells in vivo by using a biomaterial scaffold loaded with protein antigens.

227 em cells were activated and recruited to the biomaterial scaffold, and differentiated into fibroblast

228 mation should benefit the design of improved biomaterial scaffolds for medically relevant application

229 organs, by growing patient-derived cells in biomaterial scaffolds in the presence of pertinent physi

230 These data demonstrate the utility of biomaterial scaffolds loaded with disease-specific antig

231 We investigated how biomaterial scaffolds shape the immune microenvironment

232 e engineering cells are seeded within porous biomaterial scaffolds to create functional cardiac patch

233 f biologically active ChABC and NEP1-40 from biomaterial scaffolds was achieved by loading ChABC into

234 both HA content and mechanical properties of biomaterial scaffolds was required to achieve this resul

235 tn-primed human ASCs seeded in 3D-bioprinted biomaterial scaffolds yielded newly formed adipose tissu

236 evant to tissue engineers that grow cells on biomaterial scaffolds.

237 Although biomaterials scaffolds provide initially well-defined mi

238 ding cell-based therapies, tissue-engineered biomaterials, scaffolds and implantable devices, have be

239 in areas ranging from medicinal chemistry to biomaterial science.

240 brought to bear on the problem of analyzing biomaterial screening data.

241 ocessing techniques are being adapted to the biomaterials setting.

242 The ideal biomaterial should promote attachment, proliferation and

243 Groups that received biomaterials showed greater values (P <0.05).

244 ol, fumarate) gives rise to almost limitless biomaterial structural possibilities, functionality, and

245 dependent of the stiffness of the underlying biomaterial substrate, indicating subtle spectral variat

246 he first contact between bacterial cells and biomaterial substrates remain poorly understood.

247 ineage progression of stem cells cultured on biomaterial substrates with graded nanotopographies and

248 f wearable electronic devices and structural biomaterials such as cartilage.

249 The complex mechanical properties of biomaterials such as hair, horn, skin, or bone are deter

250 Nature's biomaterials such as peptides and proteins represent a v

251 Mechanical designs in other structural biomaterials, such as nacre and bone, have been studied

252 Biofilm accumulation on biomaterial surfaces is a major health concern and signi

253 step in the design of novel cell-instructive biomaterial surfaces.

254 ealing, environmental problems, and nano and biomaterials synthesis.

255 Here we report an efficient biomaterial system to generate human amnion-like tissue

256 Translational biomaterials targeted toward the regeneration of large b

257 materials have revealed that many structural biomaterials tend to be fractured, under sufficiently hi

258 As a candidate for a rapid detection of biomaterials, terahertz (THz) spectroscopy system can be

259 ysiological presentation of BMP-2 by using a biomaterial that harbors tunable mechanical properties t

260 sition has been from permissive to promoting biomaterials that are no longer bioinert but bioactive.

261 of the IEDDA reaction in the construction of biomaterials that are used for drug delivery and multimo

262 of supramolecular interactions gives rise to biomaterials that can sense and respond to physiological

263 ilar phase separation, allowing formation of biomaterials that closely mimic the material properties

264 y implemented in surface modification and as biomaterials that exhibit exceptional hydrophilicity, bi

265 ation of insulin-producing cells with porous biomaterials that function as an immune barrier.

266 partially circumvented by using macroporous biomaterials that improve the survival of transplanted s

267 Biomaterials that mimic aspects of the extracellular mat

268 There is a critical need for biomaterials that overcome this key challenge in the dev

269 Combination of these factors along with biomaterials that permit tunable release profiles would

270 to be involved in the initial attachment to biomaterials, the first stage of biofilm formation.

271 gn criteria of these multi-component fibrous biomaterials, they are used as elastomeric materials or

272 rs synthesize silk fibres, nature's toughest biomaterial, through the controlled assembly of fibroin

273 ng a timely practical guide to better assess biomaterial-tissue interactions both in vitro and in viv

274 n and embryogenesis to cancer metastasis and biomaterial-tissue interactions.

275 d in biomaterials design to induce desirable biomaterial-tissue interactions.

276 This review discusses the use of engineered biomaterials to control human cell manufacturing.

277 can provide abundant information of detected biomaterials to help deep understanding of fundamental o

278 Finally, we discuss the increasing use of biomaterials to mimic healthy and diseased hearts and ho

279 unctional proteins within defined regions of biomaterials to produce customizable structures for targ

280 These findings are relevant to the design of biomaterials to promote healing and regeneration in both

281 ing 3D scaffolds made from oxygen-generating biomaterials to tackle transport limitations deep within

282 There is an acute need for biomaterial tools that recreate the heterogeneous brain-

283 ury or disease combined with that mounted to biomaterials, transplanted cells, proteins, and gene the

284 te bovine pericardium (BP) being the primary biomaterial used in heart valve bioprostheses, recipient

285 r different types of payloads, surveying the biomaterials used to construct the functional carriers.

286 renewed interest in developing antimicrobial biomaterials using antiseptic silver ions to treat osteo

287 Chiral organizations ubiquitously exist in biomaterials via hierarchical assembly of chiral molecul

288 of thermal conductivity of aqueous and soft biomaterials was developed using microfabricated thermal

289 experienced dramatic amplification when nano-biomaterials were included in the immunosensor modificat

290 sely mimics that of cuttlebone -a structural biomaterial whose porosity exceeds that of most other na

291 We envision that supramolecular biomaterials will contribute to the development of new t

292 This new glass-ceramic biomaterial with inherent bactericidal and fungicidal pr

293 Therefore, the HCCS-PDA biomaterial with the aid of rMSCs can be used to develop

294 ilic protein that self-assembles into robust biomaterials with remarkable properties including stabil

295 Engineered biomaterials with smart and tunable properties offer an

296 using DNA to create multifunctional periodic biomaterials with tunable optical, chemical, and physica

297 n studied, including renewable cell sources, biomaterials with tunable properties, mitigation of host

298 Molecular design of biomaterials with unique features recapitulating nature'

299 Many biomaterials with unusual microstructures can be found i

300 te delivery system consisting of two natural biomaterials, zein (ZN) and chitosan (CS), to mediate or